JOP20200007A1 - عوامل، استخدامات وطرق للعلاج - Google Patents

عوامل، استخدامات وطرق للعلاج

Info

Publication number
JOP20200007A1
JOP20200007A1 JOP/2020/0007A JOP20200007A JOP20200007A1 JO P20200007 A1 JOP20200007 A1 JO P20200007A1 JO P20200007 A JOP20200007 A JO P20200007A JO P20200007 A1 JOP20200007 A1 JO P20200007A1
Authority
JO
Jordan
Prior art keywords
treatment
agents
methods
antibodies
pgrn
Prior art date
Application number
JOP/2020/0007A
Other languages
Arabic (ar)
English (en)
Inventor
Paul Parren
Soren Christensen
Ibrahim John Malik
Kasper Dyrberg Rand
Tina Stummann
Jan Egebjerg
Ronn Lars Christian Biilmann
Jeffrey B Stavenhagen
Den Brink Edward Van
Esben Trabjerg
Arnout Gerritsen
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of JOP20200007A1 publication Critical patent/JOP20200007A1/ar

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/286—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against neuromediator receptors, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JOP/2020/0007A 2017-07-20 2018-07-18 عوامل، استخدامات وطرق للعلاج JOP20200007A1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201700419 2017-07-20
PCT/EP2018/069460 WO2019016247A2 (en) 2017-07-20 2018-07-18 AGENTS, USES AND METHODS OF TREATMENT

Publications (1)

Publication Number Publication Date
JOP20200007A1 true JOP20200007A1 (ar) 2020-01-15

Family

ID=63113476

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2020/0007A JOP20200007A1 (ar) 2017-07-20 2018-07-18 عوامل، استخدامات وطرق للعلاج

Country Status (25)

Country Link
US (2) US10894833B2 (https=)
EP (1) EP3655438A2 (https=)
JP (2) JP7563975B2 (https=)
KR (1) KR102800556B1 (https=)
CN (3) CN119161481A (https=)
AR (1) AR112563A1 (https=)
AU (1) AU2018303175B2 (https=)
BR (1) BR112019005428A2 (https=)
CA (1) CA3069391A1 (https=)
CL (1) CL2020000070A1 (https=)
CO (1) CO2019014090A2 (https=)
CR (1) CR20200027A (https=)
DO (1) DOP2020000006A (https=)
EA (1) EA201992688A1 (https=)
EC (1) ECSP20002935A (https=)
IL (1) IL271728B2 (https=)
JO (1) JOP20200007A1 (https=)
MA (1) MA49633A (https=)
NI (1) NI202000005A (https=)
PE (1) PE20210467A1 (https=)
PH (1) PH12019502869A1 (https=)
RU (1) RU2019140933A (https=)
SG (1) SG11201912228WA (https=)
TW (1) TW201908342A (https=)
WO (1) WO2019016247A2 (https=)

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LT3618928T (lt) 2018-07-13 2023-04-11 Alector Llc Anti-sortilino antikūnai ir jų panaudojimo būdai
SG11202108398YA (en) * 2019-02-01 2021-08-30 Novarock Biotherapeutics Ltd Anti-claudin 18 antibodies and methods of use thereof
EP3983441A1 (en) * 2019-06-11 2022-04-20 Alector LLC Anti-sortilin antibodies for use in therapy
BR112022026508A2 (pt) * 2020-06-24 2023-03-07 Prothena Biosciences Ltd Anticorpos que reconhecem sortilina
KR20250028349A (ko) 2022-06-23 2025-02-28 드라우프니르 바이오 에이피에스 리소좀 내 세포외 표적의 분해를 선택적으로 유도하는 이작용성 분자

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Also Published As

Publication number Publication date
KR102800556B1 (ko) 2025-04-24
RU2019140933A3 (https=) 2021-10-28
CN119161480A (zh) 2024-12-20
JP7563975B2 (ja) 2024-10-08
CN110945029A (zh) 2020-03-31
WO2019016247A2 (en) 2019-01-24
AU2018303175B2 (en) 2025-01-23
CA3069391A1 (en) 2019-01-24
CR20200027A (es) 2020-04-17
JP2020527152A (ja) 2020-09-03
ECSP20002935A (es) 2020-02-28
EA201992688A1 (ru) 2020-05-20
DOP2020000006A (es) 2020-07-15
BR112019005428A2 (pt) 2019-07-16
CO2019014090A2 (es) 2020-01-17
PE20210467A1 (es) 2021-03-08
IL271728B1 (en) 2024-01-01
IL271728A (en) 2020-02-27
US20190023788A1 (en) 2019-01-24
CN119161481A (zh) 2024-12-20
EP3655438A2 (en) 2020-05-27
MA49633A (fr) 2020-05-27
AU2018303175A1 (en) 2020-01-16
TW201908342A (zh) 2019-03-01
US10894833B2 (en) 2021-01-19
IL271728B2 (en) 2024-05-01
NI202000005A (es) 2020-05-20
US20210292414A1 (en) 2021-09-23
CN110945029B (zh) 2024-10-01
SG11201912228WA (en) 2020-01-30
AR112563A1 (es) 2019-11-13
KR20200031610A (ko) 2020-03-24
JP2024119866A (ja) 2024-09-03
CL2020000070A1 (es) 2020-06-12
RU2019140933A (ru) 2021-08-20
PH12019502869A1 (en) 2020-09-28
WO2019016247A3 (en) 2019-06-20

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