JO3437B1 - أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها - Google Patents

أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها

Info

Publication number
JO3437B1
JO3437B1 JOP/2010/0374A JOP20100374A JO3437B1 JO 3437 B1 JO3437 B1 JO 3437B1 JO P20100374 A JOP20100374 A JO P20100374A JO 3437 B1 JO3437 B1 JO 3437B1
Authority
JO
Jordan
Prior art keywords
antibodies
human
fractalkin
enhanced anti
enhanced
Prior art date
Application number
JOP/2010/0374A
Other languages
Arabic (ar)
English (en)
Inventor
Nishimura Miyuki
Kawano Tetsu
Imai Toshio
Sakamoto Yoshimasa
Original Assignee
Esai R & D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43922220&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JO3437(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Esai R & D Man Co Ltd filed Critical Esai R & D Man Co Ltd
Application granted granted Critical
Publication of JO3437B1 publication Critical patent/JO3437B1/ar

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JOP/2010/0374A 2009-10-30 2010-10-27 أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها JO3437B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25652109P 2009-10-30 2009-10-30

Publications (1)

Publication Number Publication Date
JO3437B1 true JO3437B1 (ar) 2019-10-20

Family

ID=43922220

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2010/0374A JO3437B1 (ar) 2009-10-30 2010-10-27 أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها

Country Status (33)

Country Link
US (1) US8932592B2 (enExample)
EP (1) EP2493930B1 (enExample)
JP (2) JP5631991B2 (enExample)
KR (2) KR102099596B1 (enExample)
CN (1) CN102597003B (enExample)
AR (2) AR078796A1 (enExample)
AU (1) AU2010312408B2 (enExample)
BR (1) BR112012010266A2 (enExample)
CA (1) CA2778895C (enExample)
CL (2) CL2012001143A1 (enExample)
CY (1) CY1121167T1 (enExample)
DK (1) DK2493930T3 (enExample)
ES (1) ES2698389T3 (enExample)
HR (1) HRP20181973T1 (enExample)
HU (1) HUE041952T2 (enExample)
IL (1) IL219470A (enExample)
JO (1) JO3437B1 (enExample)
LT (1) LT2493930T (enExample)
MX (1) MX2012005052A (enExample)
MY (1) MY158481A (enExample)
NZ (1) NZ599779A (enExample)
PE (1) PE20121645A1 (enExample)
PH (1) PH12012500828A1 (enExample)
PL (1) PL2493930T3 (enExample)
PT (1) PT2493930T (enExample)
RS (1) RS58142B1 (enExample)
RU (1) RU2569109C2 (enExample)
SI (1) SI2493930T1 (enExample)
SM (1) SMT201800637T1 (enExample)
TW (1) TWI414308B (enExample)
UA (1) UA105073C2 (enExample)
WO (1) WO2011052799A1 (enExample)
ZA (1) ZA201203002B (enExample)

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US9415118B2 (en) * 2013-03-13 2016-08-16 Novartis Ag Antibody drug conjugates
LT3221346T (lt) 2014-11-21 2020-11-10 Bristol-Myers Squibb Company Antikūnai, apimantys modifikuotas sunkiosios grandinės pastoviąsias sritis
KR20230125855A (ko) 2014-11-21 2023-08-29 브리스톨-마이어스 스큅 컴퍼니 Cd73에 대항한 항체 및 그의 용도
EP3159007A1 (en) 2015-10-19 2017-04-26 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating rheumatoid arthritis
JP2017154975A (ja) * 2016-02-29 2017-09-07 エーザイ・アール・アンド・ディー・マネジメント株式会社 クローン病を治療するための医薬組成物
JP2018070473A (ja) * 2016-10-26 2018-05-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 関節リウマチを治療するための医薬組成物
JP2018177701A (ja) * 2017-04-14 2018-11-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 クローン病を治療するための医薬組成物
WO2020214166A1 (en) * 2019-04-17 2020-10-22 The Governors Of The University Of Alberta Treatment of autoimmune liver disease
EP3960198A4 (en) 2019-04-23 2023-01-11 Eisai R&D Management Co., Ltd. BIOMARKERS FOR TREATMENT OF RHEUMATOID ARTHRITIS
US20230043034A1 (en) * 2019-12-09 2023-02-09 Alexion Pharmaceuticals, Inc. Anti-c5 antibody for the treatment of neuromyelitis optica spectrum disorder
CN113087795B (zh) * 2019-12-23 2025-06-10 上海普铭生物科技有限公司 针对趋化因子cx3cl1的抗体及其应用
CN116472061A (zh) 2020-10-30 2023-07-21 卫材R&D管理有限公司 药物组合物

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US6172197B1 (en) 1991-07-10 2001-01-09 Medical Research Council Methods for producing members of specific binding pairs
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CN1196733A (zh) 1995-06-30 1998-10-21 持田制药株式会社 抗Fas配体抗体和利用抗Fas配体抗体的测定方法
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Also Published As

Publication number Publication date
KR101627605B1 (ko) 2016-06-07
MY158481A (en) 2016-10-14
EP2493930A4 (en) 2013-12-04
ZA201203002B (en) 2013-06-26
JP2015027304A (ja) 2015-02-12
CL2015000114A1 (es) 2015-04-10
IL219470A (en) 2017-10-31
AU2010312408A1 (en) 2012-06-21
JP5631991B2 (ja) 2014-11-26
CN102597003B (zh) 2016-03-23
BR112012010266A2 (pt) 2016-12-06
AR109533A2 (es) 2018-12-19
IL219470A0 (en) 2012-06-28
DK2493930T3 (en) 2018-12-17
MX2012005052A (es) 2012-05-29
PL2493930T3 (pl) 2019-03-29
KR20120104560A (ko) 2012-09-21
HRP20181973T1 (hr) 2019-01-25
TW201127401A (en) 2011-08-16
EP2493930B1 (en) 2018-09-19
US20120213799A1 (en) 2012-08-23
PT2493930T (pt) 2018-11-29
LT2493930T (lt) 2019-01-10
JP2013509158A (ja) 2013-03-14
CA2778895A1 (en) 2011-05-05
TWI414308B (zh) 2013-11-11
RU2012122203A (ru) 2013-12-10
CN102597003A (zh) 2012-07-18
RU2569109C2 (ru) 2015-11-20
SMT201800637T1 (it) 2019-01-11
PE20121645A1 (es) 2012-12-06
US8932592B2 (en) 2015-01-13
WO2011052799A1 (en) 2011-05-05
CA2778895C (en) 2018-08-07
NZ599779A (en) 2014-03-28
CY1121167T1 (el) 2020-05-29
CL2012001143A1 (es) 2012-10-05
KR20160066055A (ko) 2016-06-09
KR102099596B1 (ko) 2020-04-10
EP2493930A1 (en) 2012-09-05
AU2010312408B2 (en) 2015-07-09
AR078796A1 (es) 2011-12-07
SI2493930T1 (sl) 2018-12-31
ES2698389T3 (es) 2019-02-04
RS58142B1 (sr) 2019-02-28
UA105073C2 (uk) 2014-04-10
HUE041952T2 (hu) 2019-06-28
PH12012500828A1 (en) 2013-01-07

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