UA105073C2 - Антитіло проти фракталкіну, композиція і спосіб для лікування запальних порушень - Google Patents
Антитіло проти фракталкіну, композиція і спосіб для лікування запальних порушеньInfo
- Publication number
- UA105073C2 UA105073C2 UAA201206559A UAA201206559A UA105073C2 UA 105073 C2 UA105073 C2 UA 105073C2 UA A201206559 A UAA201206559 A UA A201206559A UA A201206559 A UAA201206559 A UA A201206559A UA 105073 C2 UA105073 C2 UA 105073C2
- Authority
- UA
- Ukraine
- Prior art keywords
- composition
- inflammatory disorders
- treating inflammatory
- fractalkine antibody
- antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Abstract
Винахід належить до антитіла або його фракталкінзв'язуючого фрагмента, які специфічно зв’язують фракталкін, фармацевтичної композиції, що містить антитіло або його фракталкінзв'язуючий фрагмент, способу отримання антитіла або його фракталкінзв'язуючого фрагмента, фармацевтичної композиції, що містить антитіло або його фракталкінзв'язуючий фрагмент, нуклеїнової кислоти, вектора, клітини-хазяїна та застосування для терапевтичних цілей.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25652109P | 2009-10-30 | 2009-10-30 | |
PCT/JP2010/069653 WO2011052799A1 (en) | 2009-10-30 | 2010-10-28 | Compositions and methods for treating inflammatory disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
UA105073C2 true UA105073C2 (uk) | 2014-04-10 |
Family
ID=43922220
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA201206559A UA105073C2 (uk) | 2009-10-30 | 2010-10-28 | Антитіло проти фракталкіну, композиція і спосіб для лікування запальних порушень |
Country Status (31)
Country | Link |
---|---|
US (1) | US8932592B2 (uk) |
EP (1) | EP2493930B1 (uk) |
JP (2) | JP5631991B2 (uk) |
KR (2) | KR102099596B1 (uk) |
CN (1) | CN102597003B (uk) |
AR (2) | AR078796A1 (uk) |
AU (1) | AU2010312408B2 (uk) |
BR (1) | BR112012010266A2 (uk) |
CA (1) | CA2778895C (uk) |
CL (2) | CL2012001143A1 (uk) |
CY (1) | CY1121167T1 (uk) |
DK (1) | DK2493930T3 (uk) |
ES (1) | ES2698389T3 (uk) |
HR (1) | HRP20181973T1 (uk) |
HU (1) | HUE041952T2 (uk) |
IL (1) | IL219470A (uk) |
JO (1) | JO3437B1 (uk) |
LT (1) | LT2493930T (uk) |
MX (1) | MX2012005052A (uk) |
MY (1) | MY158481A (uk) |
NZ (1) | NZ599779A (uk) |
PE (1) | PE20121645A1 (uk) |
PL (1) | PL2493930T3 (uk) |
PT (1) | PT2493930T (uk) |
RS (1) | RS58142B1 (uk) |
RU (1) | RU2569109C2 (uk) |
SI (1) | SI2493930T1 (uk) |
TW (1) | TWI414308B (uk) |
UA (1) | UA105073C2 (uk) |
WO (1) | WO2011052799A1 (uk) |
ZA (1) | ZA201203002B (uk) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9415118B2 (en) * | 2013-03-13 | 2016-08-16 | Novartis Ag | Antibody drug conjugates |
MY189836A (en) | 2014-11-21 | 2022-03-11 | Bristol Myers Squibb Co | Antibodies against cd73 and uses thereof |
CA2968382A1 (en) | 2014-11-21 | 2016-05-26 | Bristol-Myers Squibb Company | Antibodies comprising modified heavy constant regions |
EP3159007A1 (en) | 2015-10-19 | 2017-04-26 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating rheumatoid arthritis |
JP2017154975A (ja) * | 2016-02-29 | 2017-09-07 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | クローン病を治療するための医薬組成物 |
JP2018070473A (ja) * | 2016-10-26 | 2018-05-10 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 関節リウマチを治療するための医薬組成物 |
JP2018177701A (ja) * | 2017-04-14 | 2018-11-15 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | クローン病を治療するための医薬組成物 |
WO2020214166A1 (en) * | 2019-04-17 | 2020-10-22 | The Governors Of The University Of Alberta | Treatment of autoimmune liver disease |
JPWO2020218232A1 (uk) | 2019-04-23 | 2020-10-29 | ||
CN113087795A (zh) * | 2019-12-23 | 2021-07-09 | 上海普铭生物科技有限公司 | 针对趋化因子cx3cl1的抗体及其应用 |
CN116472061A (zh) | 2020-10-30 | 2023-07-21 | 卫材R&D管理有限公司 | 药物组合物 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2919890B2 (ja) | 1988-11-11 | 1999-07-19 | メディカル リサーチ カウンスル | 単一ドメインリガンド、そのリガンドからなる受容体、その製造方法、ならびにそのリガンドおよび受容体の使用 |
US6291158B1 (en) | 1989-05-16 | 2001-09-18 | Scripps Research Institute | Method for tapping the immunological repertoire |
US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
US5397703A (en) | 1992-07-09 | 1995-03-14 | Cetus Oncology Corporation | Method for generation of antibodies to cell surface molecules |
CA2163345A1 (en) | 1993-06-16 | 1994-12-22 | Susan Adrienne Morgan | Antibodies |
US6180377B1 (en) | 1993-06-16 | 2001-01-30 | Celltech Therapeutics Limited | Humanized antibodies |
US6114507A (en) | 1995-06-30 | 2000-09-05 | Mochida Pharmaceutical Co., Ltd. | Anti-Fas ligand antibody and assay method using the anti-Fas ligand antibody |
US6096312A (en) | 1995-06-30 | 2000-08-01 | Mochida Pharmaceutical Co., Ltd. | Agent for suppressing a reduction of CD4+ lymphocytes |
CN1196733A (zh) * | 1995-06-30 | 1998-10-21 | 持田制药株式会社 | 抗Fas配体抗体和利用抗Fas配体抗体的测定方法 |
US7115379B1 (en) | 1996-01-24 | 2006-10-03 | Schering Corporation | Anti-mammalian CX3C cytokine antibodies |
US6548654B1 (en) | 1996-01-24 | 2003-04-15 | Schering Corporation | DNA encoding mammalian CX3C chemokine genes |
US6566503B2 (en) | 1996-01-24 | 2003-05-20 | Schering Corporation | Mammalian CX3C chemokine |
EP0876487B1 (en) | 1996-01-24 | 2008-03-12 | Schering Corporation | Mammalian cx3c chemokine genes |
WO1997042224A1 (en) | 1996-05-07 | 1997-11-13 | Millennium Biotherapeutics, Inc. | Neurotactin and uses therefor |
US6043086A (en) | 1996-05-07 | 2000-03-28 | Millenium Biotherapeutics, Inc. | Neurotactin and uses therefor |
SE9802729D0 (sv) | 1998-08-13 | 1998-08-13 | Astra Pharma Prod | Novel Compounds |
US6420121B1 (en) | 1998-08-31 | 2002-07-16 | Oregon Health Sciences University | Prevention of cell migration initiation with CMV US28 receptor antagonists |
JP2001218581A (ja) | 1999-11-30 | 2001-08-14 | Eisai Co Ltd | モノクローナル抗体の作製法 |
US6677321B1 (en) | 1999-12-09 | 2004-01-13 | Bruce Levin | Methods and compositions for treatment of inflammatory disease |
WO2001060406A1 (en) | 2000-02-18 | 2001-08-23 | Millennium Pharmaceuticals, Inc. | Therapeutic methods that target fractalkine or cx3cr1 |
US8647612B2 (en) | 2008-03-05 | 2014-02-11 | Encore Health, Llc | Dithiol compounds, derivatives, and treatment of presbyopia |
US20020192212A1 (en) | 2001-03-19 | 2002-12-19 | Toshio Imai | Uses of anti-CX3CR1 antibody, anti-fractalkine antibody and fractalkine |
JP4263391B2 (ja) * | 2001-03-19 | 2009-05-13 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗cx3cr1抗体、抗フラクタルカイン抗体及びフラクタルカインの利用 |
SE0101082D0 (sv) | 2001-03-27 | 2001-03-27 | Astrazeneca Ab | Novel use |
AU2002323570A1 (en) | 2001-08-30 | 2003-03-10 | Chemocentryx, Inc. | Bicyclic compounds as inhibitors of chemokine binding to us28 |
JP2006512313A (ja) | 2002-10-31 | 2006-04-13 | アムジェン インコーポレイテッド | 抗炎症剤 |
TWI374893B (en) | 2003-05-30 | 2012-10-21 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
EP1520586A1 (en) | 2003-09-30 | 2005-04-06 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Inhibition of fractalkine or of its receptor for the treatment of atopic allergic diseases |
EP1671648A4 (en) | 2003-10-02 | 2009-07-08 | Eisai R&D Man Co Ltd | PREVENTION AND TREATMENT OF GVHD |
WO2005033115A1 (en) | 2003-10-07 | 2005-04-14 | Astrazeneca Ab | New 2-substituted, 4-amino-thiazolo[4,5-d] pyrimidines, useful as chemokine receptor antagonists, esp. cx3cr1 |
EP1810979B1 (en) | 2004-09-22 | 2012-06-20 | Kyowa Hakko Kirin Co., Ltd. | STABILIZED HUMAN IgG4 ANTIBODIES |
WO2006046739A1 (ja) | 2004-10-29 | 2006-05-04 | Eisai R & D Management Co., Ltd. | 炎症性疾患治療剤 |
AR053347A1 (es) | 2005-04-06 | 2007-05-02 | Astrazeneca Ab | Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos |
UA90707C2 (en) | 2005-04-06 | 2010-05-25 | Астразенека Аб | Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives |
SI2094728T1 (sl) | 2006-10-26 | 2013-06-28 | Janssen Biotech, Inc. | Postopki za uporabo za humano-adaptivnost monoklonskih protiteles |
US20100226925A1 (en) * | 2007-09-14 | 2010-09-09 | Amgen Inc. | Homogeneous Antibody Populations |
-
2010
- 2010-10-27 JO JOP/2010/0374A patent/JO3437B1/ar active
- 2010-10-28 MY MYPI2012001924A patent/MY158481A/en unknown
- 2010-10-28 UA UAA201206559A patent/UA105073C2/uk unknown
- 2010-10-28 WO PCT/JP2010/069653 patent/WO2011052799A1/en active Application Filing
- 2010-10-28 JP JP2012520621A patent/JP5631991B2/ja active Active
- 2010-10-28 HU HUE10826929A patent/HUE041952T2/hu unknown
- 2010-10-28 SI SI201031803T patent/SI2493930T1/sl unknown
- 2010-10-28 RU RU2012122203/10A patent/RU2569109C2/ru active
- 2010-10-28 LT LTEP10826929.1T patent/LT2493930T/lt unknown
- 2010-10-28 US US13/504,742 patent/US8932592B2/en active Active
- 2010-10-28 RS RS20181424A patent/RS58142B1/sr unknown
- 2010-10-28 MX MX2012005052A patent/MX2012005052A/es active IP Right Grant
- 2010-10-28 PE PE2012000580A patent/PE20121645A1/es active IP Right Grant
- 2010-10-28 KR KR1020167014386A patent/KR102099596B1/ko active IP Right Grant
- 2010-10-28 KR KR1020127014048A patent/KR101627605B1/ko active IP Right Grant
- 2010-10-28 NZ NZ599779A patent/NZ599779A/en not_active IP Right Cessation
- 2010-10-28 PL PL10826929T patent/PL2493930T3/pl unknown
- 2010-10-28 CA CA2778895A patent/CA2778895C/en active Active
- 2010-10-28 PT PT10826929T patent/PT2493930T/pt unknown
- 2010-10-28 AU AU2010312408A patent/AU2010312408B2/en active Active
- 2010-10-28 TW TW099137131A patent/TWI414308B/zh active
- 2010-10-28 DK DK10826929.1T patent/DK2493930T3/en active
- 2010-10-28 EP EP10826929.1A patent/EP2493930B1/en active Active
- 2010-10-28 CN CN201080049138.0A patent/CN102597003B/zh active Active
- 2010-10-28 BR BR112012010266A patent/BR112012010266A2/pt not_active Application Discontinuation
- 2010-10-28 AR ARP100103947A patent/AR078796A1/es active IP Right Grant
- 2010-10-28 ES ES10826929T patent/ES2698389T3/es active Active
-
2012
- 2012-04-24 ZA ZA2012/03002A patent/ZA201203002B/en unknown
- 2012-04-29 IL IL219470A patent/IL219470A/en active IP Right Grant
- 2012-04-30 CL CL2012001143A patent/CL2012001143A1/es unknown
-
2014
- 2014-09-18 JP JP2014189668A patent/JP2015027304A/ja not_active Abandoned
-
2015
- 2015-01-15 CL CL2015000114A patent/CL2015000114A1/es unknown
-
2017
- 2017-09-15 AR ARP170102555A patent/AR109533A2/es unknown
-
2018
- 2018-11-23 HR HRP20181973TT patent/HRP20181973T1/hr unknown
- 2018-11-29 CY CY20181101274T patent/CY1121167T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UA105073C2 (uk) | Антитіло проти фракталкіну, композиція і спосіб для лікування запальних порушень | |
MX2010008096A (es) | Anticuerpos de ferroportina y metodos de uso. | |
MX2012011771A (es) | Aptameros para beta-ngf y su uso en el tratamiento de enfermedades y trastornos mediados por beta-ngf. | |
WO2010151799A3 (en) | Compounds for modulating rna binding proteins and uses therefor | |
PH12017500864A1 (en) | Anti-notch1 antibodies | |
WO2010151797A3 (en) | Compounds for modulating rna binding proteins and uses therefor | |
WO2011020783A3 (en) | Targeted immunoconjugates | |
IN2014KN02933A (uk) | ||
BR112014028785A2 (pt) | proteínas de ligação a antígeno de st2 | |
UA108912C2 (uk) | БІЛОК, ЯКИЙ ЗВ'ЯЗУЄ TNF-α | |
MX2015002873A (es) | Metodos para tratar la dermatitis atopica mediante la administracion de un antagonista de il-4r. | |
EP4324845A3 (en) | Methods and pharmaceutical composition for the treatment and the prevention of cardiomyopathy due to energy failure | |
PH12016500275A1 (en) | Antibodies | |
IN2014DN08481A (uk) | ||
MX2015005874A (es) | Anticuerpos especificos del factor de crecimiento b derivados de plaquetas y composiciones y usos de estos. | |
WO2012083969A3 (en) | Microrna for diagnosis of pancreatic cancer | |
GB2496342A (en) | Combination pharmaceutical compositions and method of treatment of vertigo, kinetosis and vegetative-vascular dystonia | |
WO2012068317A3 (en) | Methods for producing recombinant proteins | |
PH12015501687A1 (en) | Novel binding proteins from pcsk9 | |
WO2014205266A3 (en) | Compositions and methods for detecting and treating glioblastoma | |
UA105384C2 (uk) | Лікування порушень, пов'язаних з інсулінорезистентністю | |
FI20115328A (fi) | Uusia kutinaaseja, niiden tuottaminen ja käytöt | |
MX2015014198A (es) | Anticuerpos cuyo objetivo es m-csf. | |
WO2011085134A8 (en) | Methods and compositions for the diagnosis, prognosis and treatment of cancer | |
WO2011103028A3 (en) | Compositions and methods for inhibiting mmset |