UA108912C2 - БІЛОК, ЯКИЙ ЗВ'ЯЗУЄ TNF-α - Google Patents
БІЛОК, ЯКИЙ ЗВ'ЯЗУЄ TNF-αInfo
- Publication number
- UA108912C2 UA108912C2 UAA201308481A UAA201308481A UA108912C2 UA 108912 C2 UA108912 C2 UA 108912C2 UA A201308481 A UAA201308481 A UA A201308481A UA A201308481 A UAA201308481 A UA A201308481A UA 108912 C2 UA108912 C2 UA 108912C2
- Authority
- UA
- Ukraine
- Prior art keywords
- tnf
- protein
- binding protein
- binds tnf
- activity
- Prior art date
Links
Classifications
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- C07—ORGANIC CHEMISTRY
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- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
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Abstract
Винахід належить до зв'язувального білка, який зв'язує TNF-α, фармацевтичної композиції, що містить зв'язувальний білок, клітини-хазяїна, способів застосування зв'язувального білка для зниження активності TNF-α та для лікування захворювання або порушення, при якому активність TNF-α є шкідливою.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42099910P | 2010-12-08 | 2010-12-08 | |
PCT/US2011/063955 WO2012078878A2 (en) | 2010-12-08 | 2011-12-08 | TNF-α BINDING PROTEINS |
Publications (1)
Publication Number | Publication Date |
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UA108912C2 true UA108912C2 (uk) | 2015-06-25 |
Family
ID=45510463
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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UAA201308481A UA108912C2 (uk) | 2010-12-08 | 2011-12-08 | БІЛОК, ЯКИЙ ЗВ'ЯЗУЄ TNF-α |
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US (3) | US8877194B2 (uk) |
EP (1) | EP2649189A4 (uk) |
JP (1) | JP2014503202A (uk) |
KR (1) | KR20130101123A (uk) |
CN (1) | CN103459609A (uk) |
AR (1) | AR084210A1 (uk) |
AU (1) | AU2011338313A1 (uk) |
BR (1) | BR112013014278A2 (uk) |
CA (1) | CA2820671A1 (uk) |
CL (1) | CL2013001625A1 (uk) |
CO (1) | CO6781489A2 (uk) |
CR (1) | CR20130266A (uk) |
DO (1) | DOP2013000129A (uk) |
GT (1) | GT201300149A (uk) |
MX (1) | MX2013006428A (uk) |
NZ (1) | NZ612394A (uk) |
PE (1) | PE20141186A1 (uk) |
RU (1) | RU2013131007A (uk) |
SG (1) | SG191074A1 (uk) |
TW (1) | TW201307387A (uk) |
UA (1) | UA108912C2 (uk) |
UY (1) | UY33786A (uk) |
WO (1) | WO2012078878A2 (uk) |
ZA (1) | ZA201304905B (uk) |
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TW201323441A (zh) * | 2011-10-24 | 2013-06-16 | Abbvie Inc | 抗tnf之雙特異性免疫結合物 |
CA2853357A1 (en) | 2011-10-24 | 2013-05-02 | Abbvie Inc. | Immunobinders directed against tnf |
MX2014004977A (es) | 2011-10-24 | 2014-09-11 | Abbvie Inc | Inmunoaglutinantes dirigidos contra esclerostina. |
US10501531B2 (en) * | 2013-03-13 | 2019-12-10 | Prothena Biosciences Limited | Tau immunotherapy |
CN104004762B (zh) * | 2014-05-20 | 2016-03-30 | 南京医科大学附属南京儿童医院 | Tgf-r反义序列及其在制备抗气道炎症反应药物中的应用 |
US11111284B2 (en) | 2014-08-21 | 2021-09-07 | The General Hospital Corporation | Tumor necrosis factor superfamily and TNF-like ligand muteins and methods of preparing |
AR102417A1 (es) * | 2014-11-05 | 2017-03-01 | Lilly Co Eli | Anticuerpos biespecíficos anti-tnf- / anti-il-23 |
DK3277719T3 (da) | 2015-03-31 | 2022-05-02 | Sorriso Pharmaceuticals Inc | Polypeptider |
GB201510758D0 (en) | 2015-06-18 | 2015-08-05 | Ucb Biopharma Sprl | Novel TNFa structure for use in therapy |
AU2016335912B2 (en) * | 2015-10-05 | 2023-08-31 | Circle33 Llc | Antibodies with improved stability to intestinal digestion |
AU2016362777B2 (en) | 2015-12-04 | 2020-01-30 | Novartis Ag | Antibody cytokine engrafted compositions and methods of use for immunoregulation |
GB201522394D0 (en) | 2015-12-18 | 2016-02-03 | Ucb Biopharma Sprl | Antibodies |
US11326182B2 (en) | 2016-04-29 | 2022-05-10 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
WO2017189964A2 (en) | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
US20180126000A1 (en) | 2016-06-02 | 2018-05-10 | Abbvie Inc. | Glucocorticoid receptor agonist and immunoconjugates thereof |
EP3519438A1 (en) | 2016-09-30 | 2019-08-07 | VHsquared Limited | Compositions |
KR20190082263A (ko) * | 2016-11-02 | 2019-07-09 | 나노프로테아젠 | 중합체 나노입자 |
GB201621907D0 (en) * | 2016-12-21 | 2017-02-01 | Ucb Biopharma Sprl And Sanofi | Antibody epitope |
US20200158721A1 (en) * | 2017-01-26 | 2020-05-21 | Vital Biosciences, Inc. | Magnetic particle-based immunoassay and methods of using the same |
GB201701404D0 (en) * | 2017-01-27 | 2017-03-15 | Micropharm Ltd | Therapies for treating inflammatory disorders |
WO2018156180A1 (en) | 2017-02-24 | 2018-08-30 | Kindred Biosciences, Inc. | Anti-il31 antibodies for veterinary use |
CN107903323B (zh) * | 2017-11-15 | 2020-04-17 | 中国药科大学 | 抗hTNF-α全人源抗体及其用途 |
KR20200095477A (ko) | 2017-12-01 | 2020-08-10 | 애브비 인코포레이티드 | 글루코코르티코이드 수용체 작용제 및 이의 면역접합체 |
PL3743088T3 (pl) * | 2018-01-26 | 2023-03-20 | F. Hoffmann-La Roche Ag | Kompozycje i sposoby stosowania il-22 fc |
EP3746478A4 (en) * | 2018-01-29 | 2022-01-19 | The Regents of The University of California | THERAPIES AND METHODS OF TREATMENT OF TLR2-MEDIATED DISEASES AND DISORDERS |
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KR102141546B1 (ko) | 2018-12-24 | 2020-08-05 | 고려대학교 산학협력단 | 난청 예후 예측방법 및 이를 이용한 키트 |
BR112021022682A2 (pt) | 2019-05-14 | 2022-02-22 | Provention Bio Inc | Métodos e composições para prevenir diabetes do tipo 1 |
EP3986931A1 (en) | 2019-06-21 | 2022-04-27 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
AU2020294980A1 (en) | 2019-06-21 | 2022-02-17 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
CA3182445A1 (en) | 2020-06-11 | 2021-12-16 | Francisco Leon | Methods and compositions for preventing type 1 diabetes |
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DE3631229A1 (de) * | 1986-09-13 | 1988-03-24 | Basf Ag | Monoklonale antikoerper gegen humanen tumornekrosefaktor (tnf) und deren verwendung |
NZ512006A (en) * | 1996-02-09 | 2005-05-27 | Abbott Biotech Ltd | Medical treatment with human TNF-alpha antibodies |
ES2347239T3 (es) * | 2002-12-02 | 2010-10-27 | Amgen Fremont Inc. | Anticuerpos dirigidos al factor de necrosis tumoral y usos de los mismos. |
US20060024308A1 (en) | 2004-07-06 | 2006-02-02 | Roberto Crea | High affinity anti-TNF-alpha antibodies and method |
KR101457223B1 (ko) * | 2005-06-07 | 2014-11-04 | 에스바테크 - 어 노바티스 컴파니 엘엘씨 | TNFα를 억제하는 안정적이고 가용성인 항체 |
JP5723769B2 (ja) * | 2008-06-03 | 2015-05-27 | アッヴィ・インコーポレイテッド | 二重可変ドメイン免疫グロブリン及びその使用 |
EP2321422A4 (en) * | 2008-07-08 | 2013-06-19 | Abbvie Inc | PROSTAGLANDINE E2 VARIABLE DOUBLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF |
AU2011237679B2 (en) | 2010-04-07 | 2014-11-06 | Abbvie Inc. | TNF-alpha binding proteins |
AR084210A1 (es) | 2010-12-08 | 2013-05-02 | Abbott Lab | PROTEINAS DE UNION AL TNF-a |
TW201323441A (zh) * | 2011-10-24 | 2013-06-16 | Abbvie Inc | 抗tnf之雙特異性免疫結合物 |
MX2014004977A (es) * | 2011-10-24 | 2014-09-11 | Abbvie Inc | Inmunoaglutinantes dirigidos contra esclerostina. |
CA2853357A1 (en) | 2011-10-24 | 2013-05-02 | Abbvie Inc. | Immunobinders directed against tnf |
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2011
- 2011-12-07 AR ARP110104589 patent/AR084210A1/es unknown
- 2011-12-08 SG SG2013044334A patent/SG191074A1/en unknown
- 2011-12-08 AU AU2011338313A patent/AU2011338313A1/en not_active Abandoned
- 2011-12-08 PE PE2013001369A patent/PE20141186A1/es not_active Application Discontinuation
- 2011-12-08 MX MX2013006428A patent/MX2013006428A/es not_active Application Discontinuation
- 2011-12-08 CA CA2820671A patent/CA2820671A1/en not_active Abandoned
- 2011-12-08 RU RU2013131007/10A patent/RU2013131007A/ru not_active Application Discontinuation
- 2011-12-08 BR BR112013014278A patent/BR112013014278A2/pt not_active IP Right Cessation
- 2011-12-08 UA UAA201308481A patent/UA108912C2/uk unknown
- 2011-12-08 NZ NZ612394A patent/NZ612394A/en not_active IP Right Cessation
- 2011-12-08 UY UY33786A patent/UY33786A/es not_active Application Discontinuation
- 2011-12-08 US US13/314,878 patent/US8877194B2/en active Active
- 2011-12-08 JP JP2013543343A patent/JP2014503202A/ja active Pending
- 2011-12-08 EP EP11846172.2A patent/EP2649189A4/en not_active Withdrawn
- 2011-12-08 KR KR1020137017771A patent/KR20130101123A/ko not_active Application Discontinuation
- 2011-12-08 CN CN2011800653303A patent/CN103459609A/zh active Pending
- 2011-12-08 TW TW100145384A patent/TW201307387A/zh unknown
- 2011-12-08 WO PCT/US2011/063955 patent/WO2012078878A2/en active Application Filing
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2013
- 2013-06-06 DO DO2013000129A patent/DOP2013000129A/es unknown
- 2013-06-06 CL CL2013001625A patent/CL2013001625A1/es unknown
- 2013-06-07 GT GT201300149A patent/GT201300149A/es unknown
- 2013-06-07 CR CR20130266A patent/CR20130266A/es unknown
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- 2013-07-01 ZA ZA2013/04905A patent/ZA201304905B/en unknown
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2014
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2016
- 2016-02-15 US US15/044,059 patent/US20160272703A1/en not_active Abandoned
Also Published As
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MX2013006428A (es) | 2014-06-11 |
CO6781489A2 (es) | 2013-10-31 |
TW201307387A (zh) | 2013-02-16 |
US20120230911A1 (en) | 2012-09-13 |
US20160272703A1 (en) | 2016-09-22 |
BR112013014278A2 (pt) | 2017-08-01 |
AR084210A1 (es) | 2013-05-02 |
DOP2013000129A (es) | 2013-11-15 |
JP2014503202A (ja) | 2014-02-13 |
CR20130266A (es) | 2013-09-18 |
EP2649189A1 (en) | 2013-10-16 |
EP2649189A4 (en) | 2014-05-14 |
US20150111251A1 (en) | 2015-04-23 |
UY33786A (es) | 2012-01-31 |
NZ612394A (en) | 2015-07-31 |
AU2011338313A1 (en) | 2013-05-02 |
SG191074A1 (en) | 2013-08-30 |
RU2013131007A (ru) | 2015-01-20 |
GT201300149A (es) | 2014-02-21 |
WO2012078878A2 (en) | 2012-06-14 |
PE20141186A1 (es) | 2014-10-12 |
KR20130101123A (ko) | 2013-09-12 |
US8877194B2 (en) | 2014-11-04 |
CA2820671A1 (en) | 2012-06-14 |
ZA201304905B (en) | 2014-12-23 |
CL2013001625A1 (es) | 2014-02-21 |
CN103459609A (zh) | 2013-12-18 |
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