ITRM980706A0 - Composizione ad attivita' antiossidante e preventiva di alterazioni trombotiche e aterosclerotiche comprendente una carnitina ed un - Google Patents
Composizione ad attivita' antiossidante e preventiva di alterazioni trombotiche e aterosclerotiche comprendente una carnitina ed unInfo
- Publication number
- ITRM980706A0 ITRM980706A0 IT98RM000706A ITRM980706A ITRM980706A0 IT RM980706 A0 ITRM980706 A0 IT RM980706A0 IT 98RM000706 A IT98RM000706 A IT 98RM000706A IT RM980706 A ITRM980706 A IT RM980706A IT RM980706 A0 ITRM980706 A0 IT RM980706A0
- Authority
- IT
- Italy
- Prior art keywords
- carnitine
- thrombotic
- antioxidant
- composition
- preventive activity
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 1
- 230000004075 alteration Effects 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 title 1
- 230000003078 antioxidant effect Effects 0.000 title 1
- 230000003143 atherosclerotic effect Effects 0.000 title 1
- 229960004203 carnitine Drugs 0.000 title 1
- 230000003449 preventive effect Effects 0.000 title 1
- 230000001732 thrombotic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
- A23L33/165—Complexes or chelates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Inorganic Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Priority Applications (20)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998RM000706A IT1302863B1 (it) | 1998-11-13 | 1998-11-13 | Composizione ad attivita' antiossidante e preventiva di alterazionitrombotiche e aterosclerotiche comprendente una carnitina ed un |
| ARP990105588A AR021089A1 (es) | 1998-11-13 | 1999-11-04 | Composicion preventiva antioxidante contra anormalidades tromboticas y ateroscleroticas, que comprende una carnitina y un flavonoide |
| CZ20011609A CZ20011609A3 (cs) | 1998-11-13 | 1999-11-05 | Antioxidační přípravek proti tromboze a ateroskleroze obsahující propionyl- L-karnitin a flavonoid |
| AT99956311T ATE306258T1 (de) | 1998-11-13 | 1999-11-05 | Antioxidative zusammensetzung enthaltend propionyl l-carnitin und ein flavonoid gegen thrombose und atherosklerose |
| PL348515A PL201896B1 (pl) | 1998-11-13 | 1999-11-05 | Zastosowanie propionylo-L-karnityny i kwercetyny |
| DK99956311T DK1128822T3 (da) | 1998-11-13 | 1999-11-05 | Antioxidantsammensætning, der omfatter propionyl-L-carnitin og et flavonoid mod trombose og aterosklerose |
| AU12941/00A AU766402B2 (en) | 1998-11-13 | 1999-11-05 | Antioxidant composition comprising propionyl L-carnitine and a flavonoid against thrombosis and atherosclerosis |
| HU0104347A HU229061B1 (hu) | 1998-11-13 | 1999-11-05 | Propionil-L-karnitint és egy flavonoidot tartalmazó antioxidáns készítmény, amely a trombózis és az ateroszklerózis kezelésében alkalmazható |
| ES99956311T ES2249039T3 (es) | 1998-11-13 | 1999-11-05 | Composicion antioxidante que comprende propionil l-carnitina y un flavonoide contra la trombosis y la ateroesclerosis. |
| CA002350220A CA2350220C (en) | 1998-11-13 | 1999-11-05 | Antioxidant composition comprising propionyl l-carnitine and a flavonoid against thrombosis and atherosclerosis |
| PCT/IT1999/000351 WO2000028986A1 (en) | 1998-11-13 | 1999-11-05 | Antioxidant composition comprising propionyl l-carnitine and a flavonoid against thrombosis and atherosclerosis |
| SK616-2001A SK6162001A3 (en) | 1998-11-13 | 1999-11-05 | Antioxidant composition comprising propionyl l-carnitine and a flavonoid against thrombosis and atherosclerosis |
| DE69927701T DE69927701T2 (de) | 1998-11-13 | 1999-11-05 | Antioxidative zusammensetzung enthaltend propionyl l-carnitin und ein flavonoid gegen thrombose und atherosklerose |
| IL14300199A IL143001A0 (en) | 1998-11-13 | 1999-11-05 | Antioxidant composition comprising propionyl l-carnitine and a flavonoid against thrombosis and atherosclerosis |
| TR2001/01344T TR200101344T2 (tr) | 1998-11-13 | 1999-11-05 | Propionil L-karnitinden ve bir flavonoid'den oluşan antioksidan bileşim |
| EP99956311A EP1128822B1 (en) | 1998-11-13 | 1999-11-05 | Antioxidant compositioncomprising propionyl l-carnitine and a flavonoid against thrombosis and atherosclerosis |
| MA25841A MA25592A1 (fr) | 1998-11-13 | 1999-11-09 | Composition antioxydante et preventive contre les anomalies thrombotiques et atherosclerotiques comportant un carnitine et un flavonoide |
| TNTNSN99212A TNSN99212A1 (fr) | 1998-11-13 | 1999-11-11 | Composition antioxydante et preventive contre les anomalies thrombotiques et atherosclerotiques, comportant un carnitine et un flavonoide |
| NO20012338A NO20012338D0 (no) | 1998-11-13 | 2001-05-11 | Antioksydasjonsmiddel-preparat omfattende propionyl L- karnitin og et flavonoid mot trombose og aterosklerose |
| US10/453,787 US20030206895A1 (en) | 1998-11-13 | 2003-06-04 | Antioxidant composition comprising propionyl L-carnitine and a flavonoid against throm-bosis and atherosclerosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998RM000706A IT1302863B1 (it) | 1998-11-13 | 1998-11-13 | Composizione ad attivita' antiossidante e preventiva di alterazionitrombotiche e aterosclerotiche comprendente una carnitina ed un |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM980706A0 true ITRM980706A0 (it) | 1998-11-13 |
| ITRM980706A1 ITRM980706A1 (it) | 2000-05-13 |
| IT1302863B1 IT1302863B1 (it) | 2000-10-10 |
Family
ID=11406214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT1998RM000706A IT1302863B1 (it) | 1998-11-13 | 1998-11-13 | Composizione ad attivita' antiossidante e preventiva di alterazionitrombotiche e aterosclerotiche comprendente una carnitina ed un |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1128822B1 (it) |
| AR (1) | AR021089A1 (it) |
| AT (1) | ATE306258T1 (it) |
| AU (1) | AU766402B2 (it) |
| CA (1) | CA2350220C (it) |
| CZ (1) | CZ20011609A3 (it) |
| DE (1) | DE69927701T2 (it) |
| DK (1) | DK1128822T3 (it) |
| ES (1) | ES2249039T3 (it) |
| HU (1) | HU229061B1 (it) |
| IL (1) | IL143001A0 (it) |
| IT (1) | IT1302863B1 (it) |
| MA (1) | MA25592A1 (it) |
| NO (1) | NO20012338D0 (it) |
| PL (1) | PL201896B1 (it) |
| SK (1) | SK6162001A3 (it) |
| TN (1) | TNSN99212A1 (it) |
| TR (1) | TR200101344T2 (it) |
| WO (1) | WO2000028986A1 (it) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1316998B1 (it) * | 2000-03-02 | 2003-05-26 | Sigma Tau Healthscience Spa | Composizione per la prevenzione e/o il trattamento degli effetticitotossici indotti dall'uso di agenti immunosoppressori. |
| IT1317035B1 (it) * | 2000-05-30 | 2003-05-26 | Sigma Tau Healthscience Spa | Integratore ad attivita' antiossidante comprendente unaalcanoilcarnitina ed una associazione di polifenoli estratti dal |
| US7338971B2 (en) * | 2001-08-30 | 2008-03-04 | El-Naggar Mawaheb M | Treatment of inflammatory, cancer, and thrombosis disorders |
| US6923960B2 (en) | 2001-10-03 | 2005-08-02 | Vsl Pharmaceuticals Inc. | Antioxidant combination composition and use thereof |
| GB0819960D0 (en) * | 2008-10-31 | 2008-12-10 | Provexis Natural Products Ltd | Therapeutic composition |
| EP2353596A1 (en) * | 2010-02-02 | 2011-08-10 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Combination composition, comprising as active ingredients L-carnitine or propionyl L-carnitine, for the prevention or treatment of chronic venous insufficiency |
| JP5923044B2 (ja) * | 2010-04-09 | 2016-05-24 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニＳｉｇｍａ−Ｔａｕ Ｉｎｄｕｓｔｒｉｅ Ｆａｒｍａｃｅｕｔｉｃｈｅ Ｒｉｕｎｉｔｅ Ｓｏｃｉｅｔａ Ｐｅｒ Ａｚｉｏｎｉ | 活性成分としてｌ−カルニチンまたはプロピオニルｌ−カルニチンを含む慢性静脈不全の予防または治療のための併用組成物 |
| US10391096B2 (en) * | 2011-10-13 | 2019-08-27 | Quercegen Pharmaceuticals Llc | Method for treating thrombotic disorders using quercetin-containing compositions |
| BR112021010500A2 (pt) | 2018-11-30 | 2021-08-24 | Beth Israel Deaconess Medical Center, Inc. | Método para reduzir a p-selectina solúvel em um paciente com câncer, método para reduzir ou prevenir a formação de um trombo em um paciente com câncer, método para promover a regressão tumoral em um paciente com câncer, método para estabilizar ou reduzir o câncer metastático em um paciente com câncer, composição farmacêutica para reduzir a p-selectina solúvel em um paciente com câncer, composição farmacêutica para reduzir ou prevenir a formação de um trombo em um paciente com câncer, composição farmacêutica para promover a regressão tumoral em um paciente com câncer e composição farmacêutica para estabilizar ou reduzir câncer metastático em um paciente com câncer |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1275434B (it) * | 1995-05-19 | 1997-08-07 | Farmila Farma Milano | Composizioni farmaceutiche e/o dietetiche ad attivita' antiossidante |
| ATE185949T1 (de) * | 1995-07-28 | 1999-11-15 | Herbert Schlachter | Zwei-phasen-präparat |
| WO1998033494A1 (en) * | 1997-02-04 | 1998-08-06 | Kosbab John V | Compositions and methods for prevention and treatment of vascular degenerative diseases |
| US5976568A (en) * | 1997-02-21 | 1999-11-02 | Medical Doctors' Research Institute, Inc. | Modular system of dietary supplement compositions for optimizing health benefits and methods |
| DE59809565D1 (de) * | 1997-12-17 | 2003-10-16 | Meta Handelsgesellschaft M B H | Trinkflüssigkeit |
| DE19806890A1 (de) * | 1998-02-19 | 1999-08-26 | Beiersdorf Ag | Kosmetische und dermatologische Wirkstoffkombinationen aus mindestens einer Substanz gewählt aus der Gruppe, bestehend aus Carnitin und den Acylcarnitinen, und mindestens einem Antioxidans sowie Zubereitungen mit einem Gehalt an solchen Wirkstoffkombinationen |
| EP0960572A1 (en) * | 1998-05-12 | 1999-12-01 | N.V. Nutricia | Nutritional composition for the treatment of pressure ulcers |
| IT1299191B1 (it) * | 1998-06-23 | 2000-02-29 | Sigma Tau Healthscience Spa | Composizione atta a prevenire e trattare l'osteoporosi e le alterazioni legate alla menopausa |
-
1998
- 1998-11-13 IT IT1998RM000706A patent/IT1302863B1/it active IP Right Grant
-
1999
- 1999-11-04 AR ARP990105588A patent/AR021089A1/es unknown
- 1999-11-05 CZ CZ20011609A patent/CZ20011609A3/cs unknown
- 1999-11-05 WO PCT/IT1999/000351 patent/WO2000028986A1/en active IP Right Grant
- 1999-11-05 IL IL14300199A patent/IL143001A0/xx unknown
- 1999-11-05 DE DE69927701T patent/DE69927701T2/de not_active Expired - Lifetime
- 1999-11-05 CA CA002350220A patent/CA2350220C/en not_active Expired - Fee Related
- 1999-11-05 ES ES99956311T patent/ES2249039T3/es not_active Expired - Lifetime
- 1999-11-05 HU HU0104347A patent/HU229061B1/hu not_active IP Right Cessation
- 1999-11-05 SK SK616-2001A patent/SK6162001A3/sk unknown
- 1999-11-05 TR TR2001/01344T patent/TR200101344T2/xx unknown
- 1999-11-05 AT AT99956311T patent/ATE306258T1/de active
- 1999-11-05 EP EP99956311A patent/EP1128822B1/en not_active Expired - Lifetime
- 1999-11-05 AU AU12941/00A patent/AU766402B2/en not_active Ceased
- 1999-11-05 PL PL348515A patent/PL201896B1/pl unknown
- 1999-11-05 DK DK99956311T patent/DK1128822T3/da active
- 1999-11-09 MA MA25841A patent/MA25592A1/fr unknown
- 1999-11-11 TN TNTNSN99212A patent/TNSN99212A1/fr unknown
-
2001
- 2001-05-11 NO NO20012338A patent/NO20012338D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU1294100A (en) | 2000-06-05 |
| NO20012338L (no) | 2001-05-11 |
| ES2249039T3 (es) | 2006-03-16 |
| DE69927701T2 (de) | 2006-07-20 |
| EP1128822A1 (en) | 2001-09-05 |
| WO2000028986A1 (en) | 2000-05-25 |
| HUP0104347A2 (hu) | 2002-04-29 |
| PL348515A1 (en) | 2002-06-03 |
| HU229061B1 (hu) | 2013-07-29 |
| CZ20011609A3 (cs) | 2002-01-16 |
| HUP0104347A3 (en) | 2003-01-28 |
| EP1128822B1 (en) | 2005-10-12 |
| TR200101344T2 (tr) | 2001-10-22 |
| CA2350220A1 (en) | 2000-05-25 |
| AR021089A1 (es) | 2002-06-12 |
| DE69927701D1 (de) | 2006-02-23 |
| CA2350220C (en) | 2008-06-17 |
| ATE306258T1 (de) | 2005-10-15 |
| MA25592A1 (fr) | 2002-12-31 |
| TNSN99212A1 (fr) | 2005-11-10 |
| SK6162001A3 (en) | 2001-10-08 |
| IL143001A0 (en) | 2002-04-21 |
| PL201896B1 (pl) | 2009-05-29 |
| ITRM980706A1 (it) | 2000-05-13 |
| IT1302863B1 (it) | 2000-10-10 |
| NO20012338D0 (no) | 2001-05-11 |
| AU766402B2 (en) | 2003-10-16 |
| DK1128822T3 (da) | 2006-02-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |