HUP0104347A2 - Propionil-L-karnitint és egy flavonoidot tartalmazó antioxidáns készítmény, amely a trombózis és az ateroszklerózis kezelésében alkalmazható - Google Patents

Propionil-L-karnitint és egy flavonoidot tartalmazó antioxidáns készítmény, amely a trombózis és az ateroszklerózis kezelésében alkalmazható

Info

Publication number
HUP0104347A2
HUP0104347A2 HU0104347A HUP0104347A HUP0104347A2 HU P0104347 A2 HUP0104347 A2 HU P0104347A2 HU 0104347 A HU0104347 A HU 0104347A HU P0104347 A HUP0104347 A HU P0104347A HU P0104347 A2 HUP0104347 A2 HU P0104347A2
Authority
HU
Hungary
Prior art keywords
flavonoid
carnitine
propionyl
atherosclerosis
antioxidant composition
Prior art date
Application number
HU0104347A
Other languages
English (en)
Inventor
Claudio Cavazza
Original Assignee
Sigma-Tau Healthscience S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Healthscience S.P.A. filed Critical Sigma-Tau Healthscience S.P.A.
Publication of HUP0104347A2 publication Critical patent/HUP0104347A2/hu
Publication of HUP0104347A3 publication Critical patent/HUP0104347A3/hu
Publication of HU229061B1 publication Critical patent/HU229061B1/hu

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • A23L33/165Complexes or chelates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

A tal lm nyban egy olyan készítményre vonatkozik, melyben a jellemzőaktív hatóanyagok a propionil-L-karnitin és egy flavonoid - típikusana kvercetin vagy annak 3-rutinozidja, a rutin - a szabadgy"k"k és atrombotikus vagy ateroszklerotikus eltérések okozta sz mos kóroseltérés és patológi s llapot megelőzésére és/vagy ter pi s kezelésére;a készítmény lehet étrendi kiegészítő, étrendi pótlék vagy egygyógyszer. Ó
HU0104347A 1998-11-13 1999-11-05 Propionil-L-karnitint és egy flavonoidot tartalmazó antioxidáns készítmény, amely a trombózis és az ateroszklerózis kezelésében alkalmazható HU229061B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998RM000706A IT1302863B1 (it) 1998-11-13 1998-11-13 Composizione ad attivita' antiossidante e preventiva di alterazionitrombotiche e aterosclerotiche comprendente una carnitina ed un
PCT/IT1999/000351 WO2000028986A1 (en) 1998-11-13 1999-11-05 Antioxidant composition comprising propionyl l-carnitine and a flavonoid against thrombosis and atherosclerosis

Publications (3)

Publication Number Publication Date
HUP0104347A2 true HUP0104347A2 (hu) 2002-04-29
HUP0104347A3 HUP0104347A3 (en) 2003-01-28
HU229061B1 HU229061B1 (hu) 2013-07-29

Family

ID=11406214

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104347A HU229061B1 (hu) 1998-11-13 1999-11-05 Propionil-L-karnitint és egy flavonoidot tartalmazó antioxidáns készítmény, amely a trombózis és az ateroszklerózis kezelésében alkalmazható

Country Status (19)

Country Link
EP (1) EP1128822B1 (hu)
AR (1) AR021089A1 (hu)
AT (1) ATE306258T1 (hu)
AU (1) AU766402B2 (hu)
CA (1) CA2350220C (hu)
CZ (1) CZ20011609A3 (hu)
DE (1) DE69927701T2 (hu)
DK (1) DK1128822T3 (hu)
ES (1) ES2249039T3 (hu)
HU (1) HU229061B1 (hu)
IL (1) IL143001A0 (hu)
IT (1) IT1302863B1 (hu)
MA (1) MA25592A1 (hu)
NO (1) NO20012338D0 (hu)
PL (1) PL201896B1 (hu)
SK (1) SK6162001A3 (hu)
TN (1) TNSN99212A1 (hu)
TR (1) TR200101344T2 (hu)
WO (1) WO2000028986A1 (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1316998B1 (it) * 2000-03-02 2003-05-26 Sigma Tau Healthscience Spa Composizione per la prevenzione e/o il trattamento degli effetticitotossici indotti dall'uso di agenti immunosoppressori.
IT1317035B1 (it) * 2000-05-30 2003-05-26 Sigma Tau Healthscience Spa Integratore ad attivita' antiossidante comprendente unaalcanoilcarnitina ed una associazione di polifenoli estratti dal
US7338971B2 (en) * 2001-08-30 2008-03-04 El-Naggar Mawaheb M Treatment of inflammatory, cancer, and thrombosis disorders
US6923960B2 (en) 2001-10-03 2005-08-02 Vsl Pharmaceuticals Inc. Antioxidant combination composition and use thereof
GB0819960D0 (en) * 2008-10-31 2008-12-10 Provexis Natural Products Ltd Therapeutic composition
EP2353596A1 (en) * 2010-02-02 2011-08-10 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Combination composition, comprising as active ingredients L-carnitine or propionyl L-carnitine, for the prevention or treatment of chronic venous insufficiency
KR101758949B1 (ko) * 2010-04-09 2017-07-17 시구마-토우인더스트리에파아마슈우티히리유니트에스.피이.에이. 활성 성분으로 l-카르니틴 또는 프로피오닐 l-카르니틴을 포함하는, 만성 정맥 기능부전의 예방 또는 치료용 복합 조성물
US10391096B2 (en) * 2011-10-13 2019-08-27 Quercegen Pharmaceuticals Llc Method for treating thrombotic disorders using quercetin-containing compositions
BR112021010500A2 (pt) 2018-11-30 2021-08-24 Beth Israel Deaconess Medical Center, Inc. Método para reduzir a p-selectina solúvel em um paciente com câncer, método para reduzir ou prevenir a formação de um trombo em um paciente com câncer, método para promover a regressão tumoral em um paciente com câncer, método para estabilizar ou reduzir o câncer metastático em um paciente com câncer, composição farmacêutica para reduzir a p-selectina solúvel em um paciente com câncer, composição farmacêutica para reduzir ou prevenir a formação de um trombo em um paciente com câncer, composição farmacêutica para promover a regressão tumoral em um paciente com câncer e composição farmacêutica para estabilizar ou reduzir câncer metastático em um paciente com câncer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1275434B (it) * 1995-05-19 1997-08-07 Farmila Farma Milano Composizioni farmaceutiche e/o dietetiche ad attivita' antiossidante
EP0755633B1 (de) * 1995-07-28 1999-10-27 Herbert Schlachter Zwei-Phasen-Präparat
AU6141498A (en) * 1997-02-04 1998-08-25 John V. Kosbab Compositions and methods for prevention and treatment of vascular degenerative diseases
US5976568A (en) * 1997-02-21 1999-11-02 Medical Doctors' Research Institute, Inc. Modular system of dietary supplement compositions for optimizing health benefits and methods
EP0928565B1 (de) * 1997-12-17 2003-09-10 Meta Handelsgesellschaft m.b.H. Trinkflüssigkeit
DE19806890A1 (de) * 1998-02-19 1999-08-26 Beiersdorf Ag Kosmetische und dermatologische Wirkstoffkombinationen aus mindestens einer Substanz gewählt aus der Gruppe, bestehend aus Carnitin und den Acylcarnitinen, und mindestens einem Antioxidans sowie Zubereitungen mit einem Gehalt an solchen Wirkstoffkombinationen
ID24710A (id) * 1998-05-12 2000-08-03 Nutricia Nv Komposisi nutrisi untuk perawatan luka karena tekanan
IT1299191B1 (it) * 1998-06-23 2000-02-29 Sigma Tau Healthscience Spa Composizione atta a prevenire e trattare l'osteoporosi e le alterazioni legate alla menopausa

Also Published As

Publication number Publication date
IL143001A0 (en) 2002-04-21
CA2350220A1 (en) 2000-05-25
DE69927701T2 (de) 2006-07-20
AR021089A1 (es) 2002-06-12
CA2350220C (en) 2008-06-17
ATE306258T1 (de) 2005-10-15
NO20012338L (no) 2001-05-11
AU766402B2 (en) 2003-10-16
NO20012338D0 (no) 2001-05-11
IT1302863B1 (it) 2000-10-10
ITRM980706A0 (it) 1998-11-13
SK6162001A3 (en) 2001-10-08
MA25592A1 (fr) 2002-12-31
PL201896B1 (pl) 2009-05-29
ITRM980706A1 (it) 2000-05-13
WO2000028986A1 (en) 2000-05-25
HU229061B1 (hu) 2013-07-29
TNSN99212A1 (fr) 2005-11-10
PL348515A1 (en) 2002-06-03
DE69927701D1 (de) 2006-02-23
DK1128822T3 (da) 2006-02-06
CZ20011609A3 (cs) 2002-01-16
ES2249039T3 (es) 2006-03-16
HUP0104347A3 (en) 2003-01-28
TR200101344T2 (tr) 2001-10-22
EP1128822B1 (en) 2005-10-12
EP1128822A1 (en) 2001-09-05
AU1294100A (en) 2000-06-05

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Legal Events

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GB9A Succession in title

Owner name: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P., IT

Free format text: FORMER OWNER(S): SIGMA-TAU HEALTHSCIENCE S.P.A., IT

MM4A Lapse of definitive patent protection due to non-payment of fees