IT9047650A1 - Composizioni farmaceutiche a base di ciclosporine. - Google Patents
Composizioni farmaceutiche a base di ciclosporine.Info
- Publication number
- IT9047650A1 IT9047650A1 IT047650A IT4765090A IT9047650A1 IT 9047650 A1 IT9047650 A1 IT 9047650A1 IT 047650 A IT047650 A IT 047650A IT 4765090 A IT4765090 A IT 4765090A IT 9047650 A1 IT9047650 A1 IT 9047650A1
- Authority
- IT
- Italy
- Prior art keywords
- pharmaceutical compositions
- cyclosporine
- cyclosporine pharmaceutical
- compositions
- pharmaceutical
- Prior art date
Links
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
- 108010036949 Cyclosporine Proteins 0.000 title 1
- 229960001265 ciclosporin Drugs 0.000 title 1
- 229930182912 cyclosporin Natural products 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898903804A GB8903804D0 (en) | 1989-02-20 | 1989-02-20 | Improvements in or relating to organic compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT9047650A0 IT9047650A0 (it) | 1990-02-20 |
| IT9047650A1 true IT9047650A1 (it) | 1990-08-21 |
| IT1240765B IT1240765B (it) | 1993-12-17 |
Family
ID=10651981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT47650A IT1240765B (it) | 1989-02-20 | 1990-02-20 | Composizioni farmaceutiche a base di ciclosporine. |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPH0611703B2 (it) |
| BE (1) | BE1005236A3 (it) |
| CH (1) | CH680650A5 (it) |
| CY (1) | CY1886A (it) |
| DE (1) | DE4005190A1 (it) |
| FR (1) | FR2643262B1 (it) |
| GB (2) | GB8903804D0 (it) |
| HK (1) | HK149595A (it) |
| IT (1) | IT1240765B (it) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639724A (en) | 1984-07-24 | 1997-06-17 | Sandoz Ltd. | Cyclosporin galenic forms |
| GB8904182D0 (en) * | 1989-02-23 | 1989-04-05 | Glaxo Canada | Pharmaceutical compositions |
| HU208491B (en) * | 1990-11-27 | 1993-11-29 | Gyogyszerkutato Intezet | Process for producing oral pharmaceutical composition containing cyclosporin |
| US6262022B1 (en) | 1992-06-25 | 2001-07-17 | Novartis Ag | Pharmaceutical compositions containing cyclosporin as the active agent |
| GB9113872D0 (en) * | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
| AU688920B2 (en) * | 1991-06-27 | 1998-03-19 | Novartis Ag | Transesterified corn oil products |
| IL102236A0 (en) * | 1991-06-27 | 1993-01-14 | Ltt Inst Co Ltd | Topical preparations containing cyclosporin |
| WO1993023010A1 (en) | 1992-05-13 | 1993-11-25 | Sandoz Ltd. | Ophthalmic compositions containing a cyclosporin |
| US5759566A (en) * | 1992-07-28 | 1998-06-02 | Poli Industria Chimica Spa | Microemulsion pharmaceutical compositions for the delivery of pharmaceutically active agents |
| DK0589843T3 (da) | 1992-09-25 | 2002-04-02 | Novartis Ag | Cyclosporinholdige farmaceutiske præparater |
| DE4310643A1 (de) * | 1993-04-01 | 1994-10-06 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| SK283442B6 (sk) † | 1993-04-20 | 2003-07-01 | Novartis Ag | Farmaceutický prípravok na orálne podanie |
| DE4412201A1 (de) * | 1993-04-20 | 1994-11-10 | Rentschler Arzneimittel | Neue pharmazeutische Zubereitungen zur oralen Verabreichung enthaltend Cyclosporin |
| NZ247516A (en) * | 1993-04-28 | 1995-02-24 | Bernard Charles Sherman | Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant |
| DE4322826A1 (de) * | 1993-07-08 | 1995-01-12 | Galenik Labor Freiburg Gmbh | Pharmazeutisches Präparat |
| DE4340781C3 (de) * | 1993-11-30 | 2000-01-27 | Novartis Ag | Cyclosporin enthaltende flüssige Zubereitungen und Verfahren zu ihrer Herstellung |
| US5891846A (en) * | 1994-02-17 | 1999-04-06 | Shiseido Company, Ltd. | Cyclosporin-containing emulsion composition |
| WO1995022343A1 (fr) * | 1994-02-17 | 1995-08-24 | Shiseido Company, Ltd. | Composition d'emulsion a base de cyclosporine |
| GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
| US5474979A (en) * | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
| DE69511539T2 (de) * | 1994-06-01 | 2000-03-30 | Yuhan Corp., Seoul/Soul | Eine cyclosporin enthaltende zubereitung und ein verfahren für ihre herstellung |
| ATE218359T1 (de) | 1994-11-03 | 2002-06-15 | Novartis Erfind Verwalt Gmbh | Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung |
| US5603951A (en) * | 1994-11-09 | 1997-02-18 | Hanmi Pharm. Ind. Co., Ltd. | Cyclosporin-containing soft capsule compositions |
| KR0167613B1 (ko) * | 1994-12-28 | 1999-01-15 | 한스 루돌프 하우스, 니콜 케르커 | 사이클로스포린-함유 연질캅셀제 조성물 |
| US5834017A (en) * | 1995-08-25 | 1998-11-10 | Sangstat Medical Corporation | Oral cyclopsporin formulations |
| US5827822A (en) * | 1996-03-25 | 1998-10-27 | Sangstat Medical Corporation | Cyclosporin a formulations as nanoparticles |
| US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| US5766629A (en) * | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| DE19549852B4 (de) | 1995-11-29 | 2009-06-04 | Novartis Ag | Cyclosporin enthaltende Präparate |
| CZ288631B6 (cs) * | 1996-01-18 | 2001-08-15 | Galena, A. S. | Léčivé přípravky s obsahem cyklosporinu |
| US5858401A (en) * | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
| JP2000516256A (ja) | 1997-01-30 | 2000-12-05 | ノバルティス アクチエンゲゼルシャフト | サイクロスポリンaを含む無油医薬組成物 |
| EP0973502A1 (en) * | 1997-03-12 | 2000-01-26 | Abbott Laboratories | Lipophilic binary systems for the administration of lipophilic compounds |
| CZ301382B6 (cs) * | 1997-03-12 | 2010-02-10 | Abbott Laboratories Chad377/Ap6D-2 | Hydrofilní binární systémy pro podávání cyklosporinu |
| RU2202346C2 (ru) | 1997-07-29 | 2003-04-20 | Фармация Энд Апджон Компани | Фармацевтическая композиция для кислотных липофильных соединений в форме самоэмульгирующейся композиции |
| DK0999838T3 (da) * | 1997-07-29 | 2002-07-08 | Upjohn Co | Selv-emulgerende formulering for lipofile forbindelser |
| US6187747B1 (en) | 1997-09-08 | 2001-02-13 | Panacea Biotech Limited | Pharmaceutical composition comprising cyclosporin |
| US6008191A (en) * | 1997-09-08 | 1999-12-28 | Panacea Biotec Limited | Pharmaceutical compositions containing cyclosporin |
| US6346511B1 (en) | 1997-09-08 | 2002-02-12 | Panacea Biotec Limited | Pharmaceutical composition comprising cyclosporin |
| US5981607A (en) * | 1998-01-20 | 1999-11-09 | Allergan | Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers |
| ID25908A (id) * | 1998-03-06 | 2000-11-09 | Novartis Ag | Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida |
| DE19859910C2 (de) * | 1998-12-23 | 2001-03-22 | Ratiopharm Gmbh | Orales Arzneimittel |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| GB9912476D0 (en) | 1999-05-28 | 1999-07-28 | Novartis Ag | Organic compounds |
| GB2362573A (en) * | 2000-05-25 | 2001-11-28 | Cipla Ltd | Cyclosporin formulation |
| AU2127400A (en) * | 1999-11-02 | 2001-05-14 | Cipla Limited | A pharmaceutical composition for the administration of water-insoluble pharmaceutically active substances and process for preparation thereof |
| PT1151755E (pt) * | 2000-05-04 | 2005-05-31 | Panacea Biotec Ltd | Composicoes farmaceuticas compreendendo a ciclosporina como substancia activa |
| DE10030378A1 (de) * | 2000-06-21 | 2002-03-14 | Audit Inst For Medical Service | Neue pharmazeutische Zusammensetzung zur topischen Anwendung von wasserunlöslichen und/oder schwer wasserlöslichen Wirkstoffen |
| CA2461730C (en) | 2001-10-19 | 2012-05-15 | Isotechnika Inc. | Novel cyclosporin analog microemulsion preconcentrates |
| US6979672B2 (en) | 2002-12-20 | 2005-12-27 | Polichem, S.A. | Cyclosporin-based pharmaceutical compositions |
| JP4381037B2 (ja) | 2003-06-04 | 2009-12-09 | 花王株式会社 | 油脂組成物 |
| EP1885342B8 (en) | 2005-03-21 | 2016-06-22 | Teva Czech Industries s.r.o. | Crystallization inhibitor and its use in gelatin capsules |
| EP2985026B1 (en) | 2005-04-15 | 2022-08-03 | Clarus Therapeutics, Inc. | Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same |
| US8492369B2 (en) | 2010-04-12 | 2013-07-23 | Clarus Therapeutics Inc | Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same |
| FR2914188B1 (fr) * | 2007-03-28 | 2012-06-22 | Trophos | Nouvelle composition a base d'oxime de cholest-4-en-3-one |
| GB2451811A (en) | 2007-08-09 | 2009-02-18 | Ems Sa | Delivery composition for solubilising water-insoluble pharmaceutical active ingredients |
| US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
| CA2690490C (en) * | 2010-01-19 | 2012-06-26 | Accucaps Industries Limited | Pharmaceutical formulations of loratadine for encapsulation and combinations thereof |
| US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US20180153904A1 (en) | 2010-11-30 | 2018-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
| ES2944263T3 (es) * | 2014-01-16 | 2023-06-20 | Maruho Kk | Agente tópico para administración transdérmica |
| WO2016033556A1 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS |
| US20170246187A1 (en) | 2014-08-28 | 2017-08-31 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
| US20160361322A1 (en) | 2015-06-15 | 2016-12-15 | Lipocine Inc. | Composition and method for oral delivery of androgen prodrugs |
| CA3078723A1 (en) | 2016-11-28 | 2018-05-31 | Nachiappan Chidambaram | Oral testosterone undecanoate therapy |
| CA3107214A1 (en) | 2018-07-20 | 2020-01-23 | Lipocine Inc. | Liver disease |
| SG11202111251SA (en) | 2019-04-11 | 2021-11-29 | R P Scherer Technologies Llc | Formulation for oral delivery of proteins, peptides and small molecules with poor permeability |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI65914C (fi) * | 1978-03-07 | 1984-08-10 | Sandoz Ag | Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a |
| CH641356A5 (en) * | 1979-02-27 | 1984-02-29 | Sandoz Ag | Pharmaceutical compositions containing cyclosporin |
| AU558155B2 (en) * | 1982-02-01 | 1987-01-22 | Sandoz Ltd. | Treating multiple sclerosis with dihydro-cyclosporin d |
-
1989
- 1989-02-20 GB GB898903804A patent/GB8903804D0/en active Pending
-
1990
- 1990-02-16 GB GB9003616A patent/GB2228198B/en not_active Expired - Lifetime
- 1990-02-16 CH CH504/90A patent/CH680650A5/de not_active IP Right Cessation
- 1990-02-19 BE BE9000181A patent/BE1005236A3/fr not_active IP Right Cessation
- 1990-02-19 DE DE4005190A patent/DE4005190A1/de not_active Ceased
- 1990-02-19 FR FR9002086A patent/FR2643262B1/fr not_active Expired - Lifetime
- 1990-02-19 JP JP2038168A patent/JPH0611703B2/ja not_active Expired - Lifetime
- 1990-02-20 IT IT47650A patent/IT1240765B/it active IP Right Grant
-
1995
- 1995-09-21 HK HK149595A patent/HK149595A/xx not_active IP Right Cessation
-
1996
- 1996-04-05 CY CY188696A patent/CY1886A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE1005236A3 (fr) | 1993-06-08 |
| JPH02255623A (ja) | 1990-10-16 |
| IT1240765B (it) | 1993-12-17 |
| GB2228198A (en) | 1990-08-22 |
| IT9047650A0 (it) | 1990-02-20 |
| CY1886A (en) | 1996-04-05 |
| FR2643262A1 (fr) | 1990-08-24 |
| HK149595A (en) | 1995-09-29 |
| GB8903804D0 (en) | 1989-04-05 |
| GB9003616D0 (en) | 1990-04-11 |
| GB2228198B (en) | 1992-12-16 |
| CH680650A5 (it) | 1992-10-15 |
| DE4005190A1 (de) | 1990-08-23 |
| JPH0611703B2 (ja) | 1994-02-16 |
| FR2643262B1 (fr) | 1993-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970226 |