GB2228198B - Novel cyclosporin galenic forms - Google Patents

Novel cyclosporin galenic forms

Info

Publication number
GB2228198B
GB2228198B GB9003616A GB9003616A GB2228198B GB 2228198 B GB2228198 B GB 2228198B GB 9003616 A GB9003616 A GB 9003616A GB 9003616 A GB9003616 A GB 9003616A GB 2228198 B GB2228198 B GB 2228198B
Authority
GB
United Kingdom
Prior art keywords
galenic forms
novel cyclosporin
cyclosporin galenic
novel
forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB9003616A
Other versions
GB9003616D0 (en
GB2228198A (en
Inventor
Ulrich Posanski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10651981&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB2228198(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB9003616D0 publication Critical patent/GB9003616D0/en
Publication of GB2228198A publication Critical patent/GB2228198A/en
Application granted granted Critical
Publication of GB2228198B publication Critical patent/GB2228198B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB9003616A 1989-02-20 1990-02-16 Novel cyclosporin galenic forms Expired - Lifetime GB2228198B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898903804A GB8903804D0 (en) 1989-02-20 1989-02-20 Improvements in or relating to organic compounds

Publications (3)

Publication Number Publication Date
GB9003616D0 GB9003616D0 (en) 1990-04-11
GB2228198A GB2228198A (en) 1990-08-22
GB2228198B true GB2228198B (en) 1992-12-16

Family

ID=10651981

Family Applications (2)

Application Number Title Priority Date Filing Date
GB898903804A Pending GB8903804D0 (en) 1984-07-24 1989-02-20 Improvements in or relating to organic compounds
GB9003616A Expired - Lifetime GB2228198B (en) 1989-02-20 1990-02-16 Novel cyclosporin galenic forms

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB898903804A Pending GB8903804D0 (en) 1984-07-24 1989-02-20 Improvements in or relating to organic compounds

Country Status (9)

Country Link
JP (1) JPH0611703B2 (en)
BE (1) BE1005236A3 (en)
CH (1) CH680650A5 (en)
CY (1) CY1886A (en)
DE (1) DE4005190A1 (en)
FR (1) FR2643262B1 (en)
GB (2) GB8903804D0 (en)
HK (1) HK149595A (en)
IT (1) IT1240765B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7799340B2 (en) 1996-01-22 2010-09-21 Watson Laboratories, Inc. Pharmaceutical compositions for lipophilic drugs
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
GB8904182D0 (en) * 1989-02-23 1989-04-05 Glaxo Canada Pharmaceutical compositions
HU208491B (en) * 1990-11-27 1993-11-29 Gyogyszerkutato Intezet Process for producing oral pharmaceutical composition containing cyclosporin
GB9113872D0 (en) * 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
IL102236A0 (en) * 1991-06-27 1993-01-14 Ltt Inst Co Ltd Topical preparations containing cyclosporin
AU688920B2 (en) * 1991-06-27 1998-03-19 Novartis Ag Transesterified corn oil products
SG45449A1 (en) 1992-05-13 1998-01-16 Sandoz Ltd Ophthalmic compositions
US5759566A (en) * 1992-07-28 1998-06-02 Poli Industria Chimica Spa Microemulsion pharmaceutical compositions for the delivery of pharmaceutically active agents
ES2168271T3 (en) * 1992-09-25 2002-06-16 Novartis Ag PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLOSPORINS.
DE4412201A1 (en) * 1993-04-20 1994-11-10 Rentschler Arzneimittel New pharmaceutical preparations for oral administration containing cyclosporin
PT697881E (en) † 1993-04-20 2002-10-31 Novartis Ag NEW PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLOSPORINE FOR ORAL ADMINISTRATION
NZ247516A (en) * 1993-04-28 1995-02-24 Bernard Charles Sherman Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant
DE4322826A1 (en) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmaceutical preparation
DE4340781C3 (en) * 1993-11-30 2000-01-27 Novartis Ag Liquid preparations containing cyclosporin and process for their preparation
US5891846A (en) * 1994-02-17 1999-04-06 Shiseido Company, Ltd. Cyclosporin-containing emulsion composition
EP0694308A4 (en) * 1994-02-17 1997-09-10 Shiseido Co Ltd Cyclosporin-containing emulsion composition
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
US5474979A (en) * 1994-05-17 1995-12-12 Allergan, Inc. Nonirritating emulsions for sensitive tissue
PT789580E (en) 1994-11-03 2002-09-30 Novartis Ag CYCLOSPORINE FORMULATIONS FOR ORAL ADMINISTRATION WITH SIMPLE COMPOSITION AND HIGH BIODISPONIBILITY AND PROCESS FOR ITS PRODUCTION
US5603951A (en) * 1994-11-09 1997-02-18 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
KR0167613B1 (en) * 1994-12-28 1999-01-15 한스 루돌프 하우스, 니콜 케르커 Cyclosporin-containing soft capsule compositions
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) * 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
DE19549852B4 (en) 1995-11-29 2009-06-04 Novartis Ag Cyclosporin containing preparations
CZ288631B6 (en) * 1996-01-18 2001-08-15 Galena, A. S. Therapeutic preparations containing cyclosporin
CZ295207B6 (en) 1997-01-30 2005-06-15 Novartis Ag Hard gelatin capsule containing cyclosporin A
TR199902199T2 (en) * 1997-03-12 2002-06-21 Abbott Laboratories Hydrophilic binary systems for cyclosporine administration.
JP2001515491A (en) * 1997-03-12 2001-09-18 アボツト・ラボラトリーズ Lipophilic binary system for administration of lipophilic compounds
RU2202346C2 (en) * 1997-07-29 2003-04-20 Фармация Энд Апджон Компани Pharmaceutical composition for acid lipophilic compounds in form of self-emulsifying composition
BR9810866B1 (en) 1997-07-29 2010-07-13 pharmaceutical composition in a self-emulsifying formulation form for lipophilic compounds.
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
US5981607A (en) * 1998-01-20 1999-11-09 Allergan Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers
ID25908A (en) * 1998-03-06 2000-11-09 Novartis Ag EMULSION PRACTONCENTRATES CONTAINING CYCLOSPORINE OR MACROLIDES
DE19859910C2 (en) * 1998-12-23 2001-03-22 Ratiopharm Gmbh Oral medicine
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
GB9912476D0 (en) 1999-05-28 1999-07-28 Novartis Ag Organic compounds
AU2127400A (en) * 1999-11-02 2001-05-14 Cipla Limited A pharmaceutical composition for the administration of water-insoluble pharmaceutically active substances and process for preparation thereof
GB2362573A (en) * 2000-05-25 2001-11-28 Cipla Ltd Cyclosporin formulation
PT1151755E (en) * 2000-05-04 2005-05-31 Panacea Biotec Ltd PHARMACEUTICAL COMPOSITIONS UNDERSTANDING CYCLOSPORIN AS AN ACTIVE SUBSTANCE
DE10030378A1 (en) * 2000-06-21 2002-03-14 Audit Inst For Medical Service New pharmaceutical composition for topical application of water-insoluble and / or poorly water-soluble active ingredients
US6979672B2 (en) 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
JP4381037B2 (en) 2003-06-04 2009-12-09 花王株式会社 Oil composition
US8673351B2 (en) 2005-03-21 2014-03-18 Ivax Pharmaceuticals S.R.O. Crystallization inhibitor and its use in gelatin capsules
EP2985026B1 (en) 2005-04-15 2022-08-03 Clarus Therapeutics, Inc. Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same
US8492369B2 (en) 2010-04-12 2013-07-23 Clarus Therapeutics Inc Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same
FR2914188B1 (en) * 2007-03-28 2012-06-22 Trophos NEW CHOLEST-4-EN-3-ONE OXIME COMPOSITION
GB2451811A (en) 2007-08-09 2009-02-18 Ems Sa Delivery composition for solubilising water-insoluble pharmaceutical active ingredients
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
CA2690490C (en) * 2010-01-19 2012-06-26 Accucaps Industries Limited Pharmaceutical formulations of loratadine for encapsulation and combinations thereof
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
JP6448553B2 (en) 2014-01-16 2019-01-09 マルホ株式会社 External preparation for transdermal administration
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US20180147215A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy
CA3134550A1 (en) * 2019-04-11 2020-10-15 R.P. Scherer Technologies, Llc Formulation for oral delivery of proteins, peptides and small molecules with poor permeability

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4388307A (en) * 1978-03-07 1983-06-14 Sandoz Ltd. Galenical compositions
BE895724A (en) * 1982-02-01 1983-07-28 Sandoz Sa NEW THERAPEUTIC USE OF DIHYDROCYCLOSPORIN D

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH641356A5 (en) * 1979-02-27 1984-02-29 Sandoz Ag Pharmaceutical compositions containing cyclosporin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4388307A (en) * 1978-03-07 1983-06-14 Sandoz Ltd. Galenical compositions
BE895724A (en) * 1982-02-01 1983-07-28 Sandoz Sa NEW THERAPEUTIC USE OF DIHYDROCYCLOSPORIN D

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7799340B2 (en) 1996-01-22 2010-09-21 Watson Laboratories, Inc. Pharmaceutical compositions for lipophilic drugs
US7988995B1 (en) 1996-01-22 2011-08-02 Watson Laboratories, Inc. Pharmaceutical compositions for lipophilic drugs
US8119157B2 (en) 1996-01-22 2012-02-21 Watson Laboratories, Inc. Pharmaceutical compositions for lipophilic drugs
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters

Also Published As

Publication number Publication date
GB8903804D0 (en) 1989-04-05
CY1886A (en) 1996-04-05
DE4005190A1 (en) 1990-08-23
IT1240765B (en) 1993-12-17
GB9003616D0 (en) 1990-04-11
JPH02255623A (en) 1990-10-16
CH680650A5 (en) 1992-10-15
GB2228198A (en) 1990-08-22
IT9047650A1 (en) 1990-08-21
IT9047650A0 (en) 1990-02-20
FR2643262A1 (en) 1990-08-24
FR2643262B1 (en) 1993-06-11
JPH0611703B2 (en) 1994-02-16
BE1005236A3 (en) 1993-06-08
HK149595A (en) 1995-09-29

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PE20 Patent expired after termination of 20 years

Expiry date: 20100215