IT9019220A1 - Combinazione di un inibitore della hmg coa reduttasi e di un inibitore della squalene sintetasi per fare abbassare il colesterolo nel siero - Google Patents

Combinazione di un inibitore della hmg coa reduttasi e di un inibitore della squalene sintetasi per fare abbassare il colesterolo nel siero

Info

Publication number
IT9019220A1
IT9019220A1 IT019220A IT1922090A IT9019220A1 IT 9019220 A1 IT9019220 A1 IT 9019220A1 IT 019220 A IT019220 A IT 019220A IT 1922090 A IT1922090 A IT 1922090A IT 9019220 A1 IT9019220 A1 IT 9019220A1
Authority
IT
Italy
Prior art keywords
inhibitor
synthetase
combination
coa reductase
serum cholesterol
Prior art date
Application number
IT019220A
Other languages
English (en)
Other versions
IT9019220A0 (it
IT1238080B (it
Inventor
Scott A Biller
Eric M Gordon
Donald S Karanewsky
William A Scott
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT9019220A0 publication Critical patent/IT9019220A0/it
Publication of IT9019220A1 publication Critical patent/IT9019220A1/it
Application granted granted Critical
Publication of IT1238080B publication Critical patent/IT1238080B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT01922090A 1989-02-01 1990-02-01 Combinazione di un inibitore della hmg coa reduttasi e di un inibitoredella squalene sintetasi per fare abbassare il colesterolo nel siero IT1238080B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30534389A 1989-02-01 1989-02-01

Publications (3)

Publication Number Publication Date
IT9019220A0 IT9019220A0 (it) 1990-02-01
IT9019220A1 true IT9019220A1 (it) 1990-08-02
IT1238080B IT1238080B (it) 1993-07-05

Family

ID=23180410

Family Applications (1)

Application Number Title Priority Date Filing Date
IT01922090A IT1238080B (it) 1989-02-01 1990-02-01 Combinazione di un inibitore della hmg coa reduttasi e di un inibitoredella squalene sintetasi per fare abbassare il colesterolo nel siero

Country Status (6)

Country Link
JP (1) JPH02235821A (it)
CA (1) CA2007643A1 (it)
DE (1) DE4002836C2 (it)
FR (1) FR2642311B1 (it)
GB (1) GB2227662B (it)
IT (1) IT1238080B (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05239075A (ja) * 1991-08-27 1993-09-17 Eisai Co Ltd 含リンイソプレノイド誘導体
EP0688325A1 (en) 1993-03-08 1995-12-27 Eisai Co., Ltd. Phosphonic acid derivatives
AU4988100A (en) * 1999-05-07 2000-11-21 Brigham And Women's Hospital Use of hmgcoa reductase inhibitors in the prevention of diseases whose pathogenesis is dependent on neovascularization
DE10038043B4 (de) * 2000-08-02 2006-09-07 Walter, Michael, Dr. Phamakologisch wirksame Substanz zur Behandlung kardiovaskulärer Erkrankungen
AUPR549901A0 (en) 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
CN1547475B (zh) 2001-07-27 2010-12-15 生命健康科学有限公司 含电子转移试剂的磷酸酯衍生物的皮肤制剂
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
AU2003901812A0 (en) * 2003-04-15 2003-05-01 Vital Health Sciences Pty Ltd Phosphates of secondary alcohols
JP4847437B2 (ja) 2004-03-03 2011-12-28 バイタル ヘルス サイエンシズ プロプライアタリー リミティド アルカロイド製剤
AR054368A1 (es) * 2005-06-01 2007-06-20 Takeda Pharmaceutical Metodo para tratar hiperlipidemia
MX2007015949A (es) 2005-06-17 2008-03-07 Vital Health Sciences Pty Ltd Un vehiculo que comprende uno o mas derivados de fosfato de di- y/o mono-(agentes de transferencia de electrones) o complejos de los mismos.
AU2011213557B2 (en) 2010-02-05 2015-05-07 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
RU2553350C2 (ru) 2010-03-30 2015-06-10 Фосфейдженикс Лимитед Трансдермальные пластыри
WO2012122586A1 (en) 2011-03-15 2012-09-20 Phosphagenics Limited New composition
EP3383371B1 (en) 2015-12-09 2024-05-01 Avecho Biotechnology Limited Pharmaceutical formulation
JP7198754B2 (ja) 2016-12-21 2023-01-04 アベーチョ バイオテクノロジー リミテッド 方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE503210C2 (sv) * 1987-05-22 1996-04-22 Squibb & Sons Inc Fosforhaltiga HMG- CoA- Reduktasinhibitoret, nya intermediat och sätt
US4871721A (en) * 1988-01-11 1989-10-03 E. R. Squibb & Sons, Inc. Phosphorus-containing squalene synthetase inhibitors
CA2003478A1 (en) * 1988-12-12 1990-06-12 Leonard G. Dennick Combination of an hmg coa reductase inhibitor and other type of serum cholesterol reducing agent and method for lowering serum cholesterol using such combination

Also Published As

Publication number Publication date
GB9002016D0 (en) 1990-03-28
FR2642311A1 (fr) 1990-08-03
DE4002836A1 (de) 1990-08-02
IT9019220A0 (it) 1990-02-01
FR2642311B1 (fr) 1991-10-25
JPH02235821A (ja) 1990-09-18
IT1238080B (it) 1993-07-05
DE4002836C2 (de) 1998-08-27
CA2007643A1 (en) 1990-08-01
GB2227662B (en) 1993-03-17
GB2227662A (en) 1990-08-08

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970227