FR2642311B1 - Association d'un inhibiteur de la hmg coa reductase et d'un inhibiteur de la squalene synthetase, permettant d'abaisser la cholesterolemie - Google Patents

Association d'un inhibiteur de la hmg coa reductase et d'un inhibiteur de la squalene synthetase, permettant d'abaisser la cholesterolemie

Info

Publication number
FR2642311B1
FR2642311B1 FR909001124A FR9001124A FR2642311B1 FR 2642311 B1 FR2642311 B1 FR 2642311B1 FR 909001124 A FR909001124 A FR 909001124A FR 9001124 A FR9001124 A FR 9001124A FR 2642311 B1 FR2642311 B1 FR 2642311B1
Authority
FR
France
Prior art keywords
inhibitor
cholesterolemia
lowering
combination
coa reductase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR909001124A
Other languages
English (en)
French (fr)
Other versions
FR2642311A1 (fr
Inventor
Donald S Karanewsky
Scott A Biller
Eric M Gordon
William A Scott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2642311A1 publication Critical patent/FR2642311A1/fr
Application granted granted Critical
Publication of FR2642311B1 publication Critical patent/FR2642311B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR909001124A 1989-02-01 1990-01-31 Association d'un inhibiteur de la hmg coa reductase et d'un inhibiteur de la squalene synthetase, permettant d'abaisser la cholesterolemie Expired - Fee Related FR2642311B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30534389A 1989-02-01 1989-02-01

Publications (2)

Publication Number Publication Date
FR2642311A1 FR2642311A1 (fr) 1990-08-03
FR2642311B1 true FR2642311B1 (fr) 1991-10-25

Family

ID=23180410

Family Applications (1)

Application Number Title Priority Date Filing Date
FR909001124A Expired - Fee Related FR2642311B1 (fr) 1989-02-01 1990-01-31 Association d'un inhibiteur de la hmg coa reductase et d'un inhibiteur de la squalene synthetase, permettant d'abaisser la cholesterolemie

Country Status (6)

Country Link
JP (1) JPH02235821A (it)
CA (1) CA2007643A1 (it)
DE (1) DE4002836C2 (it)
FR (1) FR2642311B1 (it)
GB (1) GB2227662B (it)
IT (1) IT1238080B (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05239075A (ja) * 1991-08-27 1993-09-17 Eisai Co Ltd 含リンイソプレノイド誘導体
EP0688325A1 (en) 1993-03-08 1995-12-27 Eisai Co., Ltd. Phosphonic acid derivatives
AU4988100A (en) * 1999-05-07 2000-11-21 Brigham And Women's Hospital Use of hmgcoa reductase inhibitors in the prevention of diseases whose pathogenesis is dependent on neovascularization
DE10038043B4 (de) * 2000-08-02 2006-09-07 Walter, Michael, Dr. Phamakologisch wirksame Substanz zur Behandlung kardiovaskulärer Erkrankungen
AUPR549901A0 (en) 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
CN1547475B (zh) 2001-07-27 2010-12-15 生命健康科学有限公司 含电子转移试剂的磷酸酯衍生物的皮肤制剂
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
AU2003901812A0 (en) * 2003-04-15 2003-05-01 Vital Health Sciences Pty Ltd Phosphates of secondary alcohols
JP4847437B2 (ja) 2004-03-03 2011-12-28 バイタル ヘルス サイエンシズ プロプライアタリー リミティド アルカロイド製剤
AR054368A1 (es) * 2005-06-01 2007-06-20 Takeda Pharmaceutical Metodo para tratar hiperlipidemia
MX2007015949A (es) 2005-06-17 2008-03-07 Vital Health Sciences Pty Ltd Un vehiculo que comprende uno o mas derivados de fosfato de di- y/o mono-(agentes de transferencia de electrones) o complejos de los mismos.
AU2011213557B2 (en) 2010-02-05 2015-05-07 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
RU2553350C2 (ru) 2010-03-30 2015-06-10 Фосфейдженикс Лимитед Трансдермальные пластыри
WO2012122586A1 (en) 2011-03-15 2012-09-20 Phosphagenics Limited New composition
EP3383371B1 (en) 2015-12-09 2024-05-01 Avecho Biotechnology Limited Pharmaceutical formulation
JP7198754B2 (ja) 2016-12-21 2023-01-04 アベーチョ バイオテクノロジー リミテッド 方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE503210C2 (sv) * 1987-05-22 1996-04-22 Squibb & Sons Inc Fosforhaltiga HMG- CoA- Reduktasinhibitoret, nya intermediat och sätt
US4871721A (en) * 1988-01-11 1989-10-03 E. R. Squibb & Sons, Inc. Phosphorus-containing squalene synthetase inhibitors
CA2003478A1 (en) * 1988-12-12 1990-06-12 Leonard G. Dennick Combination of an hmg coa reductase inhibitor and other type of serum cholesterol reducing agent and method for lowering serum cholesterol using such combination

Also Published As

Publication number Publication date
GB9002016D0 (en) 1990-03-28
FR2642311A1 (fr) 1990-08-03
DE4002836A1 (de) 1990-08-02
IT9019220A0 (it) 1990-02-01
JPH02235821A (ja) 1990-09-18
IT1238080B (it) 1993-07-05
IT9019220A1 (it) 1990-08-02
DE4002836C2 (de) 1998-08-27
CA2007643A1 (en) 1990-08-01
GB2227662B (en) 1993-03-17
GB2227662A (en) 1990-08-08

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Legal Events

Date Code Title Description
ST Notification of lapse