|
US4971791A
(en)
*
|
1985-08-26 |
1990-11-20 |
The Procter & Gamble Company |
Taste masking compositions
|
|
US5843445A
(en)
*
|
1987-06-24 |
1998-12-01 |
Autoimmune, Inc. |
Method of treating rheumatoid arthritis with type II collagen
|
|
US4857337A
(en)
*
|
1988-05-24 |
1989-08-15 |
American Home Products Corp. (Del) |
Enteric coated aspirin tablets
|
|
DK0594607T3
(da)
|
1990-03-02 |
1998-04-14 |
Autoimmune Inc |
Forøgelse af nedreguleringen af autoimmune sygdomme ved oral eller enteral indgivelse af autoantigener
|
|
FR2660317B1
(fr)
*
|
1990-03-27 |
1994-01-14 |
Seppic |
Produit filmogene destine a l'enrobage des formes solides; son procede de fabrication et produits revetus de ce produit.
|
|
IL99699A
(en)
|
1990-10-10 |
2002-04-21 |
Autoimmune Inc |
Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes
|
|
US5427614A
(en)
*
|
1992-02-14 |
1995-06-27 |
Warner-Lambert Company |
Starch based formulations
|
|
US6224911B1
(en)
*
|
1993-03-16 |
2001-05-01 |
Syntex (U.S.A.) Llc |
Process for the preparation of enteric coated pharmaceutical dosage forms
|
|
US5436011A
(en)
*
|
1993-04-16 |
1995-07-25 |
Bristol-Myers Squibb Company |
Solid pharmaceutical dosage form and a method for reducing abrasion
|
|
US5800831A
(en)
*
|
1993-07-28 |
1998-09-01 |
Pfizer Inc. |
Psoriasis treatment with polymer film
|
|
US6113893A
(en)
*
|
1993-07-28 |
2000-09-05 |
Pfizer Inc. |
Psoriasis treatment
|
|
JPH09501947A
(ja)
*
|
1993-08-30 |
1997-02-25 |
ワーナー−ランバート・コンパニー |
改良された錠剤コーティング方法
|
|
ATE414509T1
(de)
*
|
1994-07-08 |
2008-12-15 |
Astrazeneca Ab |
Aus vielen einzeleinheiten zusammengesetzte tablettierte dosisform
|
|
US5733575A
(en)
*
|
1994-10-07 |
1998-03-31 |
Bpsi Holdings, Inc. |
Enteric film coating compositions, method of coating therewith, and coated forms
|
|
US5591721A
(en)
*
|
1994-10-25 |
1997-01-07 |
Hybridon, Inc. |
Method of down-regulating gene expression
|
|
US6608035B1
(en)
|
1994-10-25 |
2003-08-19 |
Hybridon, Inc. |
Method of down-regulating gene expression
|
|
US6645943B1
(en)
|
1994-10-25 |
2003-11-11 |
Hybridon, Inc. |
Method of down-regulating gene expression
|
|
SE9500422D0
(sv)
*
|
1995-02-06 |
1995-02-06 |
Astra Ab |
New oral pharmaceutical dosage forms
|
|
US5683718A
(en)
*
|
1995-04-04 |
1997-11-04 |
Time-Cap Labs, Inc. |
Enteric coated tablet with raised identification character and method of manufacture
|
|
US5856446A
(en)
*
|
1995-07-07 |
1999-01-05 |
Autoimmune Inc. |
Method of treating rheumatoid arthritis with low dose type II collagen
|
|
US6624293B1
(en)
|
1995-08-17 |
2003-09-23 |
Hybridon, Inc. |
Modified protein kinase A-specific oligonucleotides and methods of their use
|
|
US7074768B2
(en)
|
1995-08-17 |
2006-07-11 |
Idera Pharmaceuticals, Inc. |
Modified protein kinase A-specific oligonucleotides and methods of their use
|
|
SE9600071D0
(sv)
|
1996-01-08 |
1996-01-08 |
Astra Ab |
New oral formulation of two active ingredients I
|
|
SE9600072D0
(sv)
*
|
1996-01-08 |
1996-01-08 |
Astra Ab |
New oral formulation of two active ingredients II
|
|
SE512835C2
(sv)
*
|
1996-01-08 |
2000-05-22 |
Astrazeneca Ab |
Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare
|
|
SE9600070D0
(sv)
|
1996-01-08 |
1996-01-08 |
Astra Ab |
New oral pharmaceutical dosage forms
|
|
US5807580A
(en)
*
|
1996-10-30 |
1998-09-15 |
Mcneil-Ppc, Inc. |
Film coated tablet compositions having enhanced disintegration characteristics
|
|
US20070149472A1
(en)
*
|
1997-08-13 |
2007-06-28 |
Mckay Robert |
Antisense oligonucleotide compositions and methods for the modulation of jnk proteins
|
|
US6809193B2
(en)
|
1997-08-13 |
2004-10-26 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide compositions and methods for the modulation of JNK proteins
|
|
US5877309A
(en)
|
1997-08-13 |
1999-03-02 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotides against JNK
|
|
US6133246A
(en)
*
|
1997-08-13 |
2000-10-17 |
Isis Pharmaceuticals Inc. |
Antisense oligonucleotide compositions and methods for the modulation of JNK proteins
|
|
JP2001514884A
(ja)
|
1997-08-19 |
2001-09-18 |
ハイブリドン・インク |
新規なhiv特異的合成オリゴヌクレオチド及びその使用方法
|
|
ATE241341T1
(de)
|
1997-09-10 |
2003-06-15 |
Takeda Chemical Industries Ltd |
Stabilisierte pharmazeutische zusammensetzung
|
|
US6559158B1
(en)
|
1997-11-03 |
2003-05-06 |
Ur Labs, Inc. |
Use of methylnaltrexone and related compounds to treat chronic opioid use side affects
|
|
US6274591B1
(en)
*
|
1997-11-03 |
2001-08-14 |
Joseph F. Foss |
Use of methylnaltrexone and related compounds
|
|
US20030158220A1
(en)
*
|
1997-11-03 |
2003-08-21 |
Foss Joseph F. |
Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
|
|
UA69413C2
(uk)
|
1998-05-22 |
2004-09-15 |
Брістол-Майерс Сквібб Компані |
Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції
|
|
US7122207B2
(en)
|
1998-05-22 |
2006-10-17 |
Bristol-Myers Squibb Company |
High drug load acid labile pharmaceutical composition
|
|
UA73092C2
(uk)
|
1998-07-17 |
2005-06-15 |
Брістол-Майерс Сквібб Компані |
Таблетка з ентеросолюбільним покриттям і спосіб її приготування
|
|
US6300320B1
(en)
|
1999-01-05 |
2001-10-09 |
Isis Pharmaceuticals, Inc. |
Modulation of c-jun using inhibitors of protein kinase C
|
|
US6432448B1
(en)
|
1999-02-08 |
2002-08-13 |
Fmc Corporation |
Edible coating composition
|
|
US6723342B1
(en)
|
1999-02-08 |
2004-04-20 |
Fmc Corporation |
Edible coating composition
|
|
US6878749B2
(en)
*
|
1999-09-17 |
2005-04-12 |
Novartis Ag |
Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
|
|
US6559188B1
(en)
|
1999-09-17 |
2003-05-06 |
Novartis Ag |
Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
|
|
WO2001068124A2
(en)
|
2000-03-15 |
2001-09-20 |
The Brigham And Women's Hospital, Inc. |
Suppression of vascular disorders by mucosal administration of heat shock protein peptides
|
|
DE60129552T2
(de)
|
2000-05-24 |
2008-04-17 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
E-selectin zur behandlung oder vorbeugung von schlaganfall
|
|
EP1381376B1
(en)
|
2000-11-20 |
2008-01-02 |
Sorbent Therapeutics, Inc. |
Water-absorbent polymers and their use
|
|
US6932861B2
(en)
|
2000-11-28 |
2005-08-23 |
Fmc Corporation |
Edible PGA coating composition
|
|
EP1339395A2
(en)
|
2000-11-28 |
2003-09-03 |
Fmc Corporation |
Edible pga (propylene glycol alginate) coating composition
|
|
AU2002314967B2
(en)
*
|
2001-06-05 |
2007-09-20 |
University Of Chicago |
Use of methylnaltrexone to treat immune suppression
|
|
GB0203296D0
(en)
*
|
2002-02-12 |
2002-03-27 |
Glaxo Group Ltd |
Novel composition
|
|
ES2322896T3
(es)
*
|
2002-04-29 |
2009-07-01 |
Supernus Pharmaceuticals, Inc. |
Formulaciones farmaceuticas con biodisponibilidad mejorada.
|
|
WO2004012741A1
(en)
*
|
2002-07-29 |
2004-02-12 |
Glaxo Group Limited |
Sustained release formulations comprising lamotrigine
|
|
US8637512B2
(en)
*
|
2002-07-29 |
2014-01-28 |
Glaxo Group Limited |
Formulations and method of treatment
|
|
HRP20150037T4
(hr)
|
2003-04-08 |
2022-09-02 |
Progenics Pharmaceuticals, Inc. |
Farmaceutske formulacije koje sadrže metilnaltrekson
|
|
AU2004229464A1
(en)
*
|
2003-04-08 |
2004-10-28 |
Progenics Pharmaceuticals, Inc. |
Combination therapy for constipation comprising a laxative and a peripheral opioid antagonist
|
|
BRPI0409128A
(pt)
*
|
2003-04-08 |
2006-03-28 |
Progenics Pharm Inc |
uso de antagonistas de opióides periféricos, especialmente metilnaltrexona para tratar sìndrome de intestino irritável
|
|
US20040202755A1
(en)
*
|
2003-04-08 |
2004-10-14 |
Myers Gale D. |
Speckled confection pieces
|
|
EP1633307A4
(en)
|
2003-06-03 |
2009-06-24 |
Isis Pharmaceuticals Inc |
Modulation of survivin expression
|
|
JP4771956B2
(ja)
|
2003-11-04 |
2011-09-14 |
スパーナス ファーマシューティカルズ インコーポレイテッド |
バイオアベイラビリティーエンハンサを含む第四級アンモニウム化合物の組成物
|
|
ATE493981T1
(de)
|
2003-11-04 |
2011-01-15 |
Supernus Pharmaceuticals Inc |
Einmal tägliche dosierformen von trospium
|
|
ES2571252T3
(es)
|
2004-02-06 |
2016-05-24 |
Pharmatel (R&D) Pty Ltd As Trustee For The Pharmatel (R & D) Trust |
Uso de aminosalicilatos en el síndrome de intestino irritable con predominio de diarrea
|
|
NZ554277A
(en)
|
2004-10-20 |
2010-09-30 |
Antisense Therapeutics Ltd |
Antisense modulation of integrin alpha 4 expression
|
|
EP1835933A4
(en)
|
2005-01-04 |
2015-01-07 |
Yeda Res & Dev |
HSP60, HSP60-PEPTIDES AND T-CELL VACCINES FOR IMMUNOMODULATION
|
|
MX2007008756A
(es)
*
|
2005-01-20 |
2007-09-27 |
Progenics Pharm Inc |
Uso de metilnaltrexona y compuestos relacionados para el tratamiento de disfuncion gastrointestinal postoperatoria.
|
|
US8518962B2
(en)
|
2005-03-07 |
2013-08-27 |
The University Of Chicago |
Use of opioid antagonists
|
|
US8524731B2
(en)
|
2005-03-07 |
2013-09-03 |
The University Of Chicago |
Use of opioid antagonists to attenuate endothelial cell proliferation and migration
|
|
US9662325B2
(en)
|
2005-03-07 |
2017-05-30 |
The University Of Chicago |
Use of opioid antagonists to attenuate endothelial cell proliferation and migration
|
|
ES2714198T3
(es)
|
2005-03-07 |
2019-05-27 |
Univ Chicago |
Uso de antagonistas opioideos para atenuar la proliferación y la migración de células endoteliales
|
|
EP1874334A4
(en)
*
|
2005-04-15 |
2011-03-30 |
Vascular Biogenics Ltd |
COMPOSITIONS WITH BETA 2-GLYCOPROTEIN I-PEPTIDES FOR THE PREVENTION AND / OR TREATMENT OF VASCULAR DISEASES
|
|
AR057325A1
(es)
|
2005-05-25 |
2007-11-28 |
Progenics Pharm Inc |
Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
|
|
AR057035A1
(es)
|
2005-05-25 |
2007-11-14 |
Progenics Pharm Inc |
SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
|
|
US20080194611A1
(en)
*
|
2005-06-03 |
2008-08-14 |
Alverdy John C |
Modulation of Cell Barrier Dysfunction
|
|
US20070098790A1
(en)
*
|
2005-10-31 |
2007-05-03 |
David Jiang |
Nutritional supplement for the enhancement of the health of the liver
|
|
TWI489984B
(zh)
|
2006-08-04 |
2015-07-01 |
Wyeth Corp |
用於非經腸道傳輸化合物之配方及其用途
|
|
US7731604B2
(en)
*
|
2006-10-31 |
2010-06-08 |
Taylor Made Golf Company, Inc. |
Golf club iron head
|
|
JP5495792B2
(ja)
*
|
2007-01-05 |
2014-05-21 |
チバ ホールディング インコーポレーテッド |
有機顔料とヒュームドシリカとの共粉砕
|
|
AR065877A1
(es)
|
2007-03-29 |
2009-07-08 |
Progenics Pharm Inc |
Antagonoistas del receptor opioide periferico y usos de los mismos
|
|
CA2682129A1
(en)
|
2007-03-29 |
2008-10-09 |
Progenics Pharmaceuticals, Inc. |
Crystal forms and uses thereof
|
|
JP5469593B2
(ja)
|
2007-03-29 |
2014-04-16 |
ワイス・エルエルシー |
末梢性オピオイド受容体アンタゴニストおよびその使用
|
|
MX2009012188A
(es)
|
2007-05-11 |
2010-02-24 |
Univ Jefferson |
Métodos de tratamiento y prevención de enfermedades y desórdenes neurodegenerativos.
|
|
BRPI0810336A2
(pt)
*
|
2007-05-11 |
2019-03-19 |
The Trustees Of The University Of Pennsylvania |
"método para tratar e/ou prevenir úlceras de pele em um indivíduo"
|
|
CN101896170A
(zh)
*
|
2007-11-13 |
2010-11-24 |
赫尔克里士公司 |
用于营养品和药物剂型的水分散性肠溶衣配制物
|
|
ES2709633T3
(es)
*
|
2007-12-21 |
2019-04-17 |
Dr Willmar Schwabe Gmbh & Co Kg |
Uso de un extracto de hojas de Ginkgo biloba
|
|
WO2009099411A1
(en)
|
2008-02-06 |
2009-08-13 |
Progenics Pharmaceuticals, Inc. |
Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
|
|
JP5647098B2
(ja)
|
2008-03-21 |
2014-12-24 |
ザ ユニヴァーシティー オヴ シカゴ |
オピオイド拮抗薬とmTOR阻害薬を用いた治療
|
|
WO2010002576A1
(en)
|
2008-07-01 |
2010-01-07 |
University Of Chicago |
Particles containing an opioid receptor antagonist and methods of use
|
|
US20100034959A1
(en)
*
|
2008-08-07 |
2010-02-11 |
Vector Corporation |
High solids, high molecular weight polymer coating
|
|
CA2676881C
(en)
|
2008-09-30 |
2017-04-25 |
Wyeth |
Peripheral opioid receptor antagonists and uses thereof
|
|
EP2651403B1
(en)
|
2010-12-17 |
2020-12-02 |
Glaxo Group Limited |
Use of lp-pla2 inhibitors in the treatment and prevention of eye diseases
|
|
WO2013045352A1
(de)
|
2011-09-30 |
2013-04-04 |
Basf Se |
Verfahren zur herstellung von festen pigmenthaltigen filmüberzugsmitteln in form von granulaten auf basis von magensaftresistenten filmbildnern für pharmazeutische dosierungsformen
|
|
WO2013082275A1
(en)
|
2011-11-30 |
2013-06-06 |
Trustees Of Boston College |
Inhibitors of phosphodiesterases 11 (pde11) and methods of use to elevate cortisol production
|
|
CA2857546A1
(en)
|
2011-12-01 |
2013-06-06 |
Glaxo Group Limited |
Methods of treatment and prevention of eye diseases
|
|
US8277842B1
(en)
*
|
2012-01-20 |
2012-10-02 |
Dart Neuroscience (Cayman) Ltd. |
Enteric-coated HT-2157 compositions and methods of their use
|
|
CA2908096C
(en)
|
2013-03-27 |
2022-05-03 |
Isarna Therapeutics Gmbh |
Modified tgf-beta oligonucleotides
|
|
CA3002137A1
(en)
|
2014-10-17 |
2016-04-21 |
Salix Pharmaceuticals, Inc. |
Use of methylnaltrexone to attenuate tumor progression
|
|
EP3211081A1
(en)
|
2016-02-26 |
2017-08-30 |
Secarna Pharmaceuticals GmbH & Co. KG |
Novel approach for treating inflammatory disorders
|
|
US10647987B2
(en)
|
2016-02-26 |
2020-05-12 |
Secama Pharmaceuticals GmbH & Co KG |
Approach for treating inflammatory disorders
|
|
WO2017173327A1
(en)
|
2016-03-31 |
2017-10-05 |
The Schepens Eye Research Institute, Inc. |
Endomucin inhibitor as an anti-angiogenic agent
|
|
CN110191952A
(zh)
|
2016-10-07 |
2019-08-30 |
瑟卡尔纳制药有限公司 |
治疗癌症的新方法
|
|
EP4520828A3
(en)
|
2016-11-15 |
2025-07-09 |
The Schepens Eye Research Institute, Inc. |
Compositions and methods for the treatment of aberrant angiogenesis
|
|
US11260048B2
(en)
|
2017-10-03 |
2022-03-01 |
The Schepens Eye Research Institute, Inc. |
Compounds and compositions for inhibiting retinal pigment epithelium degeneration and methods using the same
|
|
WO2019099560A1
(en)
|
2017-11-14 |
2019-05-23 |
The Schepens Eye Research Institute, Inc. |
Runx1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition
|
|
AU2020269886A1
(en)
|
2019-05-03 |
2021-12-02 |
Secarna Pharmaceuticals Gmbh & Co. Kg |
PD-L1 antisense oligonucleotides for use in tumor treatment
|