IT8420940A0 - Sali stabili della solfo-adenosil-l-metionina (same)particolarmente idonei per uso farmaceutico orale. - Google Patents
Sali stabili della solfo-adenosil-l-metionina (same)particolarmente idonei per uso farmaceutico orale.Info
- Publication number
- IT8420940A0 IT8420940A0 IT8420940A IT2094084A IT8420940A0 IT 8420940 A0 IT8420940 A0 IT 8420940A0 IT 8420940 A IT8420940 A IT 8420940A IT 2094084 A IT2094084 A IT 2094084A IT 8420940 A0 IT8420940 A0 IT 8420940A0
- Authority
- IT
- Italy
- Prior art keywords
- adenosyl
- sulfo
- methionine
- same
- particularly suitable
- Prior art date
Links
- FVSFGYXQNHBRHP-TWBCTODHSA-N (2S)-2-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-sulfoamino]-4-methylsulfanylbutanoic acid Chemical compound O[C@@H]1[C@H](O)[C@@H](CN([C@@H](CCSC)C(O)=O)S(O)(=O)=O)O[C@H]1N1C2=NC=NC(N)=C2N=C1 FVSFGYXQNHBRHP-TWBCTODHSA-N 0.000 title 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/921—Candida
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/94—Saccharomyces
- Y10S435/942—Saccharomyces cerevisiae
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Cephalosporin Compounds (AREA)
- Detergent Compositions (AREA)
Priority Applications (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20940/84A IT1173992B (it) | 1984-05-16 | 1984-05-16 | Sali stabili della solfo-adenosil-l-metionina (same) particolarmente idonei per uso farmaceutico orale |
EP85105001A EP0162324B1 (en) | 1984-05-16 | 1985-04-25 | Stable sulpho+adenosyl-l-methionine (same) salts, particularly suitable for oral pharmaceutical use |
AT85105001T ATE36541T1 (de) | 1984-05-16 | 1985-04-25 | Stabile sulpho-adenosyl-l-methionin (same)-salze, im besonderen geeignet fuer orale pharmazeutische verwendung. |
DE8585105001T DE3564436D1 (en) | 1984-05-16 | 1985-04-25 | Stable sulpho+adenosyl-l-methionine (same) salts, particularly suitable for oral pharmaceutical use |
ZA853296A ZA853296B (en) | 1984-05-16 | 1985-05-02 | Stable sulpho-adenosyl-l-methionine(same)salts,particularly suitable for oral pharmaceutical use |
IN346/CAL/85A IN162826B (it) | 1984-05-16 | 1985-05-06 | |
MX8511549U MX7438E (es) | 1984-05-16 | 1985-05-08 | Un procedimiento para producir sales estables de sulfo-adenosil-l-metionina |
US06/731,722 US5128249A (en) | 1984-05-16 | 1985-05-08 | Stable sulpho-adenosyl-l-methionine (same) salts, particularly suitable for oral pharmaceutical use |
PT80453A PT80453B (pt) | 1984-05-16 | 1985-05-13 | Processo de preparacao de sais estaveis da sulfo-adenosil-l-metionina (same) especialmente adequados para medicamento oral |
IE118885A IE58694B1 (en) | 1984-05-16 | 1985-05-13 | Stable sulpho-adenosyl-l-methionine (SAMe) salts, particularly suitable for oral pharmaceutical use |
CA000481420A CA1241611A (en) | 1984-05-16 | 1985-05-13 | Stable sulpho-adenosyl-l-methionine (same) salts, particularly suitable for oral pharmaceutical use |
YU801/85A YU44498B (en) | 1984-05-16 | 1985-05-14 | Process for obtaining stable sulphoadenozyil-l-methioninic salts |
GR851183A GR851183B (it) | 1984-05-16 | 1985-05-15 | |
NO851963A NO163744C (no) | 1984-05-16 | 1985-05-15 | Fremgangsmaate ved fremstilling av stabile salter av sulfo-adenosyl-l-methionin (same). |
DK215685A DK161971C (da) | 1984-05-16 | 1985-05-15 | Sulfo-adenosyl-l-methioninsalte, fremgangsmaade til fremstilling deraf samt farmaceutisk praeparat indeholdende et eller flere saadanne salte |
SU85A SU1487816A3 (ru) | 1984-05-16 | 1985-05-15 | СПОСОБ ПОЛУЧЕНИЯ СОЛЕЙ СУЛЬФОАДЕНОЗИЛ-ьЛ-МЕТИОНИНА |
AU42517/85A AU568435B2 (en) | 1984-05-16 | 1985-05-15 | Salts of same with sulphonic sulphuric and dioctylsulphosuccinic acids |
EG305/85A EG17393A (en) | 1984-05-16 | 1985-05-16 | Stable sulpho-adenosyl-l-methionine(same)salts,particularly suitable for oral pharmaceutical use |
JP60102795A JPH0630606B2 (ja) | 1984-05-16 | 1985-05-16 | 経口薬剤用に特に適した安定なスルホーアデノシル‐l‐メチオニン塩 |
ES543198A ES543198A0 (es) | 1984-05-16 | 1985-05-16 | Un procedimiento para producir sales estables de sulfo-ade- nosil-l-metionina |
FI851953A FI85288C (fi) | 1984-05-16 | 1985-05-16 | Foerfarande foer framstaellning av stabila sulfoadenosyl-l-metionin (same)-salter. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20940/84A IT1173992B (it) | 1984-05-16 | 1984-05-16 | Sali stabili della solfo-adenosil-l-metionina (same) particolarmente idonei per uso farmaceutico orale |
Publications (3)
Publication Number | Publication Date |
---|---|
IT8420940A0 true IT8420940A0 (it) | 1984-05-16 |
IT8420940A1 IT8420940A1 (it) | 1985-11-16 |
IT1173992B IT1173992B (it) | 1987-06-24 |
Family
ID=11174364
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT20940/84A IT1173992B (it) | 1984-05-16 | 1984-05-16 | Sali stabili della solfo-adenosil-l-metionina (same) particolarmente idonei per uso farmaceutico orale |
Country Status (21)
Country | Link |
---|---|
US (1) | US5128249A (it) |
EP (1) | EP0162324B1 (it) |
JP (1) | JPH0630606B2 (it) |
AT (1) | ATE36541T1 (it) |
AU (1) | AU568435B2 (it) |
CA (1) | CA1241611A (it) |
DE (1) | DE3564436D1 (it) |
DK (1) | DK161971C (it) |
EG (1) | EG17393A (it) |
ES (1) | ES543198A0 (it) |
FI (1) | FI85288C (it) |
GR (1) | GR851183B (it) |
IE (1) | IE58694B1 (it) |
IN (1) | IN162826B (it) |
IT (1) | IT1173992B (it) |
MX (1) | MX7438E (it) |
NO (1) | NO163744C (it) |
PT (1) | PT80453B (it) |
SU (1) | SU1487816A3 (it) |
YU (1) | YU44498B (it) |
ZA (1) | ZA853296B (it) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1173990B (it) * | 1984-05-16 | 1987-06-24 | Bioresearch Spa | Sali stabili della solfo-adenosil-l-metionina (same) particolarmente adatti per uso parenterale |
IT1177373B (it) * | 1984-12-06 | 1987-08-26 | Bioresearch Spa | Sali della 5'-metiltio-5'-deossiadenosina con acidi solfonici a lunga catena alchilica |
IT1200589B (it) * | 1985-02-14 | 1989-01-27 | Gibipharma Spa | Derivati naturali attivita farmagologica |
AU2538588A (en) * | 1987-10-09 | 1989-05-02 | Mario De Rosa | Lipophilic salts of s-adenosyl-l-methionine (sam) with acylated taurine derivatives |
GB9211779D0 (en) * | 1992-06-03 | 1992-07-15 | Ciba Geigy Ag | Amine salts |
CA2122342A1 (en) * | 1992-09-04 | 1994-03-17 | Hironori Kawabata | Pharmaceutical composition |
US6492349B1 (en) | 1993-03-31 | 2002-12-10 | Nutramax Laboratories, Inc. | Aminosugar and glycosaminoglycan composition for the treatment and repair of connective tissue |
US6255295B1 (en) | 1996-12-23 | 2001-07-03 | Nutramax Laboratories, Inc. | Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue |
IT1317920B1 (it) * | 2000-10-20 | 2003-07-15 | Univ Roma | S-adenosilmetionina e suoi derivati per il trattamento e laprevenzione della malattia di alzheimer. |
US6759395B2 (en) | 2000-12-18 | 2004-07-06 | Orchid Chemicals & Pharmaceuticals, Ltd. | Soft-gelatin capsule comprising S-adenosylmethionine and a method for producing the same |
AU2002228321A1 (en) * | 2000-12-18 | 2002-07-01 | Orchid Chemicals And Pharmaceuticals Limited | A novel soft-gelatin capsule comprising s-adenosylmethionine and a method for producing the same |
US6649753B2 (en) | 2001-06-07 | 2003-11-18 | Orchid Chemicals & Pharmaceuticals Ltd. | Stable salts of S-adenosyl-L-methionine (SAMe) and the process for their preparation |
WO2002102823A1 (en) * | 2001-06-14 | 2002-12-27 | Orchid Chemicals & Pharmaceuticals Limited | Stable salts of s-adenosyl-l-methionine (same) and the process for their preparation |
DE60102938T2 (de) * | 2001-12-12 | 2005-03-31 | Chemistry & Health International B.V. | Lagerstabile Granulate, die S-Adenosylmethionin enthalten, und Verfahren zu ihrer Herstellung |
US20050272687A1 (en) * | 2004-06-08 | 2005-12-08 | Hebert Rolland F | Stable S-adenosyl-l-methionine |
US20090012036A1 (en) * | 2005-05-24 | 2009-01-08 | Hebert Rolland F | Stable S-adenosyl-L-methionine |
US8148348B2 (en) * | 2006-01-17 | 2012-04-03 | Mitsubishi Gas Chemical Company, Inc. | Method of stabilizing S-adenosyl-L-methionine and stabilized composition |
US20090088404A1 (en) * | 2007-01-31 | 2009-04-02 | Methylation Sciences International Srl | Extended Release Pharmaceutical Formulations of S-Adenosylmethionine |
CA2677053C (en) * | 2007-01-31 | 2016-03-15 | Methylation Sciences International Srl | Extended release pharmaceutical formulations of s-adenosylmethionine |
US20090197824A1 (en) * | 2008-01-31 | 2009-08-06 | Methylation Sciences International Srl | Extended Release Pharmaceutical Formulations of S-Adenosylmethionine |
US20100004191A1 (en) * | 2008-07-01 | 2010-01-07 | Rolland F Hebert | Compositions of S-adenosyl-L-methionine. |
US8329208B2 (en) | 2009-07-28 | 2012-12-11 | Methylation Sciences International Srl | Pharmacokinetics of S-adenosylmethionine formulations |
US20110027342A1 (en) * | 2009-07-28 | 2011-02-03 | Msi Methylation Sciences, Inc. | S-adenosylmethionine formulations with enhanced bioavailability |
CN106074589A (zh) | 2012-10-17 | 2016-11-09 | 甲基化物科学国际有限公司 | 包含s‑腺苷甲硫氨酸及没食子酸酯的组合物 |
EP2945959B1 (en) | 2013-01-16 | 2020-05-13 | Hebert Sam-E LLC | Stable indole-3-propionate salts of s-adenosyl-l-methionine |
CN103265595B (zh) * | 2013-05-21 | 2015-12-23 | 南京基准生物科技有限公司 | 一种酿酒酵母发酵液中提取s-腺苷甲硫氨酸的方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE37913B1 (en) * | 1972-08-02 | 1977-11-09 | Bioresearch Sas | Salt of s-adenosyl-l-methionine |
IE39517B1 (en) * | 1973-06-27 | 1978-10-25 | Bioresearch Sas | Double salts of s-adenosyl-l-methhionine |
AR221676A1 (es) * | 1974-07-12 | 1981-03-13 | Bioresearch Sas | Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico |
JPS53107485A (en) * | 1977-02-28 | 1978-09-19 | Yamasa Shoyu Co Ltd | Preparation of s-adenosyl-l-methionine salt |
GB2064523B (en) * | 1979-12-04 | 1983-06-29 | Kanegafuchi Chemical Ind | Stable composition of s-adenosyl-l-methionine |
GB2116172B (en) * | 1982-02-25 | 1986-07-09 | Nippon Zeon Co | Microbial cells containing s-adenosyl methionine in high concentrations and process for production of s adenosyl methionine |
IT1169773B (it) * | 1983-08-24 | 1987-06-03 | Bioresearch Spa | Processo per la produzione di sali stabili della solfo-adenosil-l-metionina |
JPS60102796A (ja) * | 1983-11-09 | 1985-06-06 | 三洋電機株式会社 | リ−ドレス部品の端子接続方法 |
IT1173990B (it) * | 1984-05-16 | 1987-06-24 | Bioresearch Spa | Sali stabili della solfo-adenosil-l-metionina (same) particolarmente adatti per uso parenterale |
-
1984
- 1984-05-16 IT IT20940/84A patent/IT1173992B/it active
-
1985
- 1985-04-25 AT AT85105001T patent/ATE36541T1/de not_active IP Right Cessation
- 1985-04-25 DE DE8585105001T patent/DE3564436D1/de not_active Expired
- 1985-04-25 EP EP85105001A patent/EP0162324B1/en not_active Expired
- 1985-05-02 ZA ZA853296A patent/ZA853296B/xx unknown
- 1985-05-06 IN IN346/CAL/85A patent/IN162826B/en unknown
- 1985-05-08 MX MX8511549U patent/MX7438E/es unknown
- 1985-05-08 US US06/731,722 patent/US5128249A/en not_active Expired - Fee Related
- 1985-05-13 IE IE118885A patent/IE58694B1/en not_active IP Right Cessation
- 1985-05-13 CA CA000481420A patent/CA1241611A/en not_active Expired
- 1985-05-13 PT PT80453A patent/PT80453B/pt not_active IP Right Cessation
- 1985-05-14 YU YU801/85A patent/YU44498B/xx unknown
- 1985-05-15 DK DK215685A patent/DK161971C/da not_active IP Right Cessation
- 1985-05-15 AU AU42517/85A patent/AU568435B2/en not_active Ceased
- 1985-05-15 SU SU85A patent/SU1487816A3/ru active
- 1985-05-15 GR GR851183A patent/GR851183B/el unknown
- 1985-05-15 NO NO851963A patent/NO163744C/no unknown
- 1985-05-16 EG EG305/85A patent/EG17393A/xx active
- 1985-05-16 ES ES543198A patent/ES543198A0/es active Granted
- 1985-05-16 JP JP60102795A patent/JPH0630606B2/ja not_active Expired - Lifetime
- 1985-05-16 FI FI851953A patent/FI85288C/fi not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
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TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970530 |