IT8322110A0 - Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico. - Google Patents

Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico.

Info

Publication number
IT8322110A0
IT8322110A0 IT8322110A IT2211083A IT8322110A0 IT 8322110 A0 IT8322110 A0 IT 8322110A0 IT 8322110 A IT8322110 A IT 8322110A IT 2211083 A IT2211083 A IT 2211083A IT 8322110 A0 IT8322110 A0 IT 8322110A0
Authority
IT
Italy
Prior art keywords
phenylmidazole
preparation
pharmaceutical use
amidine derivatives
substitute processes
Prior art date
Application number
IT8322110A
Other languages
English (en)
Other versions
IT1206498B (it
Inventor
Giuseppe Bietti
Enzo Cereda
Arturo Donetti
Antonio Giachetti
Ferdinando Pagani
Original Assignee
Angeli Inst Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeli Inst Spa filed Critical Angeli Inst Spa
Publication of IT8322110A0 publication Critical patent/IT8322110A0/it
Priority to IT8322110A priority Critical patent/IT1206498B/it
Priority to AT84200659T priority patent/ATE45149T1/de
Priority to EP84200659A priority patent/EP0131973B1/en
Priority to DE8484200659T priority patent/DE3479212D1/de
Priority to US06/610,958 priority patent/US4649150A/en
Priority to FI842432A priority patent/FI842432A/fi
Priority to YU1154/84A priority patent/YU43367B/xx
Priority to JP59142099A priority patent/JPS6038367A/ja
Priority to PH30966A priority patent/PH21566A/en
Priority to PL1984254625A priority patent/PL143732B1/pl
Priority to IL72417A priority patent/IL72417A/xx
Priority to PL1984248779A priority patent/PL143303B1/pl
Priority to DD84265319A priority patent/DD232696A5/de
Priority to KR1019840004177A priority patent/KR910000661B1/ko
Priority to ZA845490A priority patent/ZA845490B/xx
Priority to SU843770847A priority patent/SU1322979A3/ru
Priority to CA000459030A priority patent/CA1257274A/en
Priority to HU842781A priority patent/HU193292B/hu
Priority to NO842921A priority patent/NO162857C/no
Priority to ES534375A priority patent/ES8505962A1/es
Priority to DK350084A priority patent/DK350084A/da
Priority to GB08418149A priority patent/GB2149395B/en
Priority to NZ208920A priority patent/NZ208920A/en
Priority to ES534376A priority patent/ES8601910A1/es
Priority to GR75327A priority patent/GR79981B/el
Priority to CS845542A priority patent/CS244141B2/cs
Priority to CS852801A priority patent/CS244150B2/cs
Priority to AU30800/84A priority patent/AU565292B2/en
Priority to PT78935A priority patent/PT78935B/pt
Priority to SU853844125A priority patent/SU1313345A3/ru
Priority to YU1126/86A priority patent/YU43701B/xx
Priority to SG486/87A priority patent/SG48687G/en
Priority to HK742/87A priority patent/HK74287A/xx
Application granted granted Critical
Publication of IT1206498B publication Critical patent/IT1206498B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatment Of Sludge (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Processing Of Solid Wastes (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT8322110A 1983-07-18 1983-07-18 Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico. IT1206498B (it)

Priority Applications (33)

Application Number Priority Date Filing Date Title
IT8322110A IT1206498B (it) 1983-07-18 1983-07-18 Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico.
AT84200659T ATE45149T1 (de) 1983-07-18 1984-05-08 Amidine derivate von 2-substituierten-4phenylimidazolen.
EP84200659A EP0131973B1 (en) 1983-07-18 1984-05-08 New amidine derivatives of 2-substituted 4-phenilimidazole
DE8484200659T DE3479212D1 (en) 1983-07-18 1984-05-08 New amidine derivatives of 2-substituted 4-phenilimidazole
US06/610,958 US4649150A (en) 1983-07-18 1984-05-16 Antiulcerogenic amidine derivatives of 2-substituted 4-phenylimidazole
FI842432A FI842432A (fi) 1983-07-18 1984-06-15 Amidinderivat av 2-substituerad 4-fenyl-imidazoler, foerfarande foer deras framstaellning och deras farmaceutiska anvaendning.
YU1154/84A YU43367B (en) 1983-07-18 1984-07-02 Process for making new amidine derivatives of 2-substituted 4-phenylimidazole
JP59142099A JPS6038367A (ja) 1983-07-18 1984-07-09 フエニルイミダゾールのアミジン誘導体
PH30966A PH21566A (en) 1983-07-18 1984-07-11 Amidine derivatives of 2-substituted 4-phenylimidazole
PL1984254625A PL143732B1 (en) 1983-07-18 1984-07-16 Method of obtaining amidine derivatives of 2-substituted 4-phenylamidazolone
IL72417A IL72417A (en) 1983-07-18 1984-07-16 Amidine derivatives of 2-substituted 4-phenylimidazole,their preparation and pharmaceutical compositions containing them
PL1984248779A PL143303B1 (en) 1983-07-18 1984-07-16 Method of obtaining novel amidino-derivatives of 2-substituted 4-phenylimidazolone
DD84265319A DD232696A5 (de) 1983-07-18 1984-07-16 Neue amidinderivate 2-substituierter 4-phenylimidazole
KR1019840004177A KR910000661B1 (ko) 1983-07-18 1984-07-16 2-치환된 4-페닐이미다졸 아미딘 유도체의 제조방법
CA000459030A CA1257274A (en) 1983-07-18 1984-07-17 Amidine derivatives of 2-substituted 4- phenylimidazole
SU843770847A SU1322979A3 (ru) 1983-07-18 1984-07-17 Способ получени производных имидазолилфениламидина или их кислотно-аддитивных солей
ZA845490A ZA845490B (en) 1983-07-18 1984-07-17 Imidazole derivatives,processes for their preparation and pharmaceutical compositions thereof
HU842781A HU193292B (en) 1983-07-18 1984-07-17 Process for production of new amidin derivatives of 2-substituated-4-phenol imidasoles
NO842921A NO162857C (no) 1983-07-18 1984-07-17 Analogifremgangsmaate for fremstilling av terapeutisk aktive amidin-derivater av 2-substituert 4-fenylimidazol.
ES534375A ES8505962A1 (es) 1983-07-18 1984-07-17 Un procedimiento para preparar nuevos derivados amidinicos de 4-fenilimidazol sustituido en la posicion 2
DK350084A DK350084A (da) 1983-07-18 1984-07-17 2-substituerede 4-phenylimidazolderivater, fremgangsmaader til fremstilling deraf samt farmaceutiske praeparater indeholdende disse
GB08418149A GB2149395B (en) 1983-07-18 1984-07-17 Amidines derived from 4-phenyl-2-substituted imidazoles
NZ208920A NZ208920A (en) 1983-07-18 1984-07-17 Phenylimidazoles and pharmaceutical compositions
ES534376A ES8601910A1 (es) 1983-07-18 1984-07-17 Un procedimiento para preparar nuevos derivados amidinicos de 4-fenilimidazol sustituido en la posicion 2
GR75327A GR79981B (it) 1983-07-18 1984-07-17
CS845542A CS244141B2 (en) 1983-07-18 1984-07-18 Method of 2-substituted 4-phenylimidazole's new amidine derivatives production
CS852801A CS244150B2 (cs) 1983-07-18 1984-07-18 Způsob výroby nových amidinových derivátů 2-substituovaného 4-fenylimidazolu
AU30800/84A AU565292B2 (en) 1983-07-18 1984-07-18 Amidine derivatives of 2-subsituted 4-phenyl imidazole
PT78935A PT78935B (de) 1983-07-18 1984-07-18 New amidine derivatives of 2-substituted 4-phenylimidazole
SU853844125A SU1313345A3 (ru) 1983-07-18 1985-01-29 Способ получени производных имидазолилфениламидина или их кислотно-аддитивных солей
YU1126/86A YU43701B (en) 1983-07-18 1986-06-26 Process for preparing new amidinic derivatives of 2-substituted 4-phenyl-imidazole
SG486/87A SG48687G (en) 1983-07-18 1987-06-03 Imidazolylphenyl amidines
HK742/87A HK74287A (en) 1983-07-18 1987-10-15 Imidazolylphenyl amidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8322110A IT1206498B (it) 1983-07-18 1983-07-18 Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico.

Publications (2)

Publication Number Publication Date
IT8322110A0 true IT8322110A0 (it) 1983-07-18
IT1206498B IT1206498B (it) 1989-04-27

Family

ID=11191639

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8322110A IT1206498B (it) 1983-07-18 1983-07-18 Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico.

Country Status (28)

Country Link
US (1) US4649150A (it)
EP (1) EP0131973B1 (it)
JP (1) JPS6038367A (it)
KR (1) KR910000661B1 (it)
AT (1) ATE45149T1 (it)
AU (1) AU565292B2 (it)
CA (1) CA1257274A (it)
CS (1) CS244141B2 (it)
DD (1) DD232696A5 (it)
DE (1) DE3479212D1 (it)
DK (1) DK350084A (it)
ES (2) ES8505962A1 (it)
FI (1) FI842432A (it)
GB (1) GB2149395B (it)
GR (1) GR79981B (it)
HK (1) HK74287A (it)
HU (1) HU193292B (it)
IL (1) IL72417A (it)
IT (1) IT1206498B (it)
NO (1) NO162857C (it)
NZ (1) NZ208920A (it)
PH (1) PH21566A (it)
PL (2) PL143732B1 (it)
PT (1) PT78935B (it)
SG (1) SG48687G (it)
SU (2) SU1322979A3 (it)
YU (2) YU43367B (it)
ZA (1) ZA845490B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888348A (en) * 1986-09-04 1989-12-19 Ciba-Geigy Corporation Substituted thioureas, isothioureas and carbodiimides
HUP0003934A3 (en) 1997-07-03 2002-01-28 Pfizer A part of diaryl imidazole derivatives, pharmaceutical composit
US6887870B1 (en) 1999-10-12 2005-05-03 Bristol-Myers Squibb Company Heterocyclic sodium/proton exchange inhibitors and method
ES2243337T3 (es) 1999-12-16 2005-12-01 Schering Corporation Imidazoles sustituidos antagonistas del receptor y5 del neuropeptido y.
FR2917087B1 (fr) 2007-06-05 2012-09-21 Galderma Res & Dev Nouveaux 4-phenyl-imidazole-2-thiones comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique.
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209431B (it) * 1980-11-28 1989-07-16 Angeli Inst Spa Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione.

Also Published As

Publication number Publication date
DE3479212D1 (en) 1989-09-07
ZA845490B (en) 1986-03-26
ES534376A0 (es) 1985-11-01
GR79981B (it) 1984-10-31
HUT34959A (en) 1985-05-28
US4649150A (en) 1987-03-10
EP0131973A1 (en) 1985-01-23
NO162857C (no) 1990-02-28
PH21566A (en) 1987-12-11
YU115484A (en) 1986-12-31
NO842921L (no) 1985-01-21
HK74287A (en) 1987-10-23
NO162857B (no) 1989-11-20
PL143732B1 (en) 1988-03-31
PL254625A1 (en) 1986-05-06
DK350084A (da) 1985-01-19
YU43367B (en) 1989-06-30
YU43701B (en) 1989-10-31
AU3080084A (en) 1985-01-24
GB2149395B (en) 1986-11-26
PT78935B (de) 1986-10-23
NZ208920A (en) 1987-03-31
CA1257274A (en) 1989-07-11
FI842432A (fi) 1985-01-19
KR910000661B1 (ko) 1991-01-31
YU112686A (en) 1987-12-31
HU193292B (en) 1987-09-28
ES534375A0 (es) 1985-06-16
CS554284A2 (en) 1985-08-15
PT78935A (de) 1984-08-01
IL72417A (en) 1988-03-31
SG48687G (en) 1987-07-24
JPS6038367A (ja) 1985-02-27
FI842432A0 (fi) 1984-06-15
EP0131973B1 (en) 1989-08-02
SU1322979A3 (ru) 1987-07-07
IL72417A0 (en) 1984-11-30
GB2149395A (en) 1985-06-12
PL248779A1 (en) 1985-12-03
ES8601910A1 (es) 1985-11-01
IT1206498B (it) 1989-04-27
ATE45149T1 (de) 1989-08-15
KR850001173A (ko) 1985-03-16
AU565292B2 (en) 1987-09-10
DK350084D0 (da) 1984-07-17
PL143303B1 (en) 1988-02-29
CS244141B2 (en) 1986-07-17
ES8505962A1 (es) 1985-06-16
GB8418149D0 (en) 1984-08-22
DD232696A5 (de) 1986-02-05
SU1313345A3 (ru) 1987-05-23

Similar Documents

Publication Publication Date Title
IT1217327B (it) Metodo per la preparazione di derivati gangliosidici e loro uso in preparazioni farmaceutiche
IT8748014A0 (it) Procedimento per la produzione di acido 3-indolpiruvico e suoi derivati loro uso farmaceutico
IT8547852A0 (it) Ciclosporine,processi per la loro preparazione,uso farmaceutico delle stesse e composizioni farmaceutiche che le contengono
IT8167545A0 (it) Derivati dell idronaftalene loro preparazione ed impiego farmaceutico
IT1153437B (it) Derivati 5-amminometil-ossazolidinici, procedimento per la loro preparazione, e loro applicazione in terapia
IT8621125A0 (it) Poli-4-aminopirrol-2-carbossamido derivati e procedimento per la loro preparazione.
IT8847871A0 (it) Ne e loro impiego come medicamenti derivati peptidici,loro preparazio-
IT1203108B (it) Procedimento per la preparazione di derivati di dipertidi e relativi prodotti ad uso farmaceutico
IT1175924B (it) Cefem derivati e procedimenti per la loro preparazione
IT8322110A0 (it) Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico.
IT8248970A0 (it) Derivati xantinici, procedimento per la loro preparazione, composizione farmaceutiche che li contengono e loro impiego terapeutico
IT8667976A0 (it) Derivati teofillinmetilditiolanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono
IT1188185B (it) 2-piridilcarbossammide particolarmente per uso farmaceutico
IT1201523B (it) Eterociclilfenilfomramidine,processi per la loro preparazione e loro uso farmaceutico
IT8320278A0 (it) Derivati delle rifamicine eprocedimento per la loro preparazione.
IT1214726B (it) Derivati di glucosilmoranolina eprocedimento per la loro preparazione
IT1157126B (it) N(vinblastin-23-il)derivati di aminoacidi loro preparazione ed applicazione terapeutica
IT1193723B (it) Derivati di 1 fenil 4 morfolino 1 buten 3 olo procedimento per la loro preparazione e loro uso farmaceutico
IT8249042A0 (it) Derivati imidazolici e procedimento per la loro preparazione
IT8748656A0 (it) Derivati azolici,procedimento per la loro produzione,preparati farmaceutici che li contengono,e loro impiego
IT1210711B (it) Derivati di amminopropilamminobleomicina e procedimento per la loro preparazione
IT1190711B (it) Derivati di alchilen-diammina e procedimento per la loro preparazione
IT1168183B (it) Terpenil aralchilamine, processi per la loro preparazione e loro uso farmaceutico
IT8220637A0 (it) Cefem derivati e procedimento per la loro preparazione.
IT8819545A0 (it) Derivati piperazinici eprocedimento per la loro preparazione.