IT8322110A0 - Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico. - Google Patents
Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico.Info
- Publication number
- IT8322110A0 IT8322110A0 IT8322110A IT2211083A IT8322110A0 IT 8322110 A0 IT8322110 A0 IT 8322110A0 IT 8322110 A IT8322110 A IT 8322110A IT 2211083 A IT2211083 A IT 2211083A IT 8322110 A0 IT8322110 A0 IT 8322110A0
- Authority
- IT
- Italy
- Prior art keywords
- phenylmidazole
- preparation
- pharmaceutical use
- amidine derivatives
- substitute processes
- Prior art date
Links
- 150000001409 amidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Treatment Of Sludge (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Processing Of Solid Wastes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Priority Applications (33)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8322110A IT1206498B (it) | 1983-07-18 | 1983-07-18 | Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico. |
| DE8484200659T DE3479212D1 (en) | 1983-07-18 | 1984-05-08 | New amidine derivatives of 2-substituted 4-phenilimidazole |
| AT84200659T ATE45149T1 (de) | 1983-07-18 | 1984-05-08 | Amidine derivate von 2-substituierten-4phenylimidazolen. |
| EP84200659A EP0131973B1 (en) | 1983-07-18 | 1984-05-08 | New amidine derivatives of 2-substituted 4-phenilimidazole |
| US06/610,958 US4649150A (en) | 1983-07-18 | 1984-05-16 | Antiulcerogenic amidine derivatives of 2-substituted 4-phenylimidazole |
| FI842432A FI842432A (fi) | 1983-07-18 | 1984-06-15 | Amidinderivat av 2-substituerad 4-fenyl-imidazoler, foerfarande foer deras framstaellning och deras farmaceutiska anvaendning. |
| YU1154/84A YU43367B (en) | 1983-07-18 | 1984-07-02 | Process for making new amidine derivatives of 2-substituted 4-phenylimidazole |
| JP59142099A JPS6038367A (ja) | 1983-07-18 | 1984-07-09 | フエニルイミダゾールのアミジン誘導体 |
| PH30966A PH21566A (en) | 1983-07-18 | 1984-07-11 | Amidine derivatives of 2-substituted 4-phenylimidazole |
| KR1019840004177A KR910000661B1 (ko) | 1983-07-18 | 1984-07-16 | 2-치환된 4-페닐이미다졸 아미딘 유도체의 제조방법 |
| PL1984248779A PL143303B1 (en) | 1983-07-18 | 1984-07-16 | Method of obtaining novel amidino-derivatives of 2-substituted 4-phenylimidazolone |
| DD84265319A DD232696A5 (de) | 1983-07-18 | 1984-07-16 | Neue amidinderivate 2-substituierter 4-phenylimidazole |
| PL1984254625A PL143732B1 (en) | 1983-07-18 | 1984-07-16 | Method of obtaining amidine derivatives of 2-substituted 4-phenylamidazolone |
| IL72417A IL72417A (en) | 1983-07-18 | 1984-07-16 | Amidine derivatives of 2-substituted 4-phenylimidazole,their preparation and pharmaceutical compositions containing them |
| NZ208920A NZ208920A (en) | 1983-07-18 | 1984-07-17 | Phenylimidazoles and pharmaceutical compositions |
| GR75327A GR79981B (it) | 1983-07-18 | 1984-07-17 | |
| ES534375A ES534375A0 (es) | 1983-07-18 | 1984-07-17 | Un procedimiento para preparar nuevos derivados amidinicos de 4-fenilimidazol sustituido en la posicion 2 |
| SU843770847A SU1322979A3 (ru) | 1983-07-18 | 1984-07-17 | Способ получени производных имидазолилфениламидина или их кислотно-аддитивных солей |
| DK350084A DK350084A (da) | 1983-07-18 | 1984-07-17 | 2-substituerede 4-phenylimidazolderivater, fremgangsmaader til fremstilling deraf samt farmaceutiske praeparater indeholdende disse |
| CA000459030A CA1257274A (en) | 1983-07-18 | 1984-07-17 | Amidine derivatives of 2-substituted 4- phenylimidazole |
| ZA845490A ZA845490B (en) | 1983-07-18 | 1984-07-17 | Imidazole derivatives,processes for their preparation and pharmaceutical compositions thereof |
| GB08418149A GB2149395B (en) | 1983-07-18 | 1984-07-17 | Amidines derived from 4-phenyl-2-substituted imidazoles |
| NO842921A NO162857C (no) | 1983-07-18 | 1984-07-17 | Analogifremgangsmaate for fremstilling av terapeutisk aktive amidin-derivater av 2-substituert 4-fenylimidazol. |
| HU842781A HU193292B (en) | 1983-07-18 | 1984-07-17 | Process for production of new amidin derivatives of 2-substituated-4-phenol imidasoles |
| ES534376A ES534376A0 (es) | 1983-07-18 | 1984-07-17 | Un procedimiento para preparar nuevos derivados amidinicos de 4-fenilimidazol sustituido en la posicion 2 |
| PT78935A PT78935B (de) | 1983-07-18 | 1984-07-18 | New amidine derivatives of 2-substituted 4-phenylimidazole |
| CS852801A CS244150B2 (cs) | 1983-07-18 | 1984-07-18 | Způsob výroby nových amidinových derivátů 2-substituovaného 4-fenylimidazolu |
| AU30800/84A AU565292B2 (en) | 1983-07-18 | 1984-07-18 | Amidine derivatives of 2-subsituted 4-phenyl imidazole |
| CS845542A CS244141B2 (en) | 1983-07-18 | 1984-07-18 | Method of 2-substituted 4-phenylimidazole's new amidine derivatives production |
| SU853844125A SU1313345A3 (ru) | 1983-07-18 | 1985-01-29 | Способ получени производных имидазолилфениламидина или их кислотно-аддитивных солей |
| YU1126/86A YU43701B (en) | 1983-07-18 | 1986-06-26 | Process for preparing new amidinic derivatives of 2-substituted 4-phenyl-imidazole |
| SG486/87A SG48687G (en) | 1983-07-18 | 1987-06-03 | Imidazolylphenyl amidines |
| HK742/87A HK74287A (en) | 1983-07-18 | 1987-10-15 | Imidazolylphenyl amidines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8322110A IT1206498B (it) | 1983-07-18 | 1983-07-18 | Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8322110A0 true IT8322110A0 (it) | 1983-07-18 |
| IT1206498B IT1206498B (it) | 1989-04-27 |
Family
ID=11191639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8322110A IT1206498B (it) | 1983-07-18 | 1983-07-18 | Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico. |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4649150A (it) |
| EP (1) | EP0131973B1 (it) |
| JP (1) | JPS6038367A (it) |
| KR (1) | KR910000661B1 (it) |
| AT (1) | ATE45149T1 (it) |
| AU (1) | AU565292B2 (it) |
| CA (1) | CA1257274A (it) |
| CS (1) | CS244141B2 (it) |
| DD (1) | DD232696A5 (it) |
| DE (1) | DE3479212D1 (it) |
| DK (1) | DK350084A (it) |
| ES (2) | ES534376A0 (it) |
| FI (1) | FI842432A (it) |
| GB (1) | GB2149395B (it) |
| GR (1) | GR79981B (it) |
| HK (1) | HK74287A (it) |
| HU (1) | HU193292B (it) |
| IL (1) | IL72417A (it) |
| IT (1) | IT1206498B (it) |
| NO (1) | NO162857C (it) |
| NZ (1) | NZ208920A (it) |
| PH (1) | PH21566A (it) |
| PL (2) | PL143732B1 (it) |
| PT (1) | PT78935B (it) |
| SG (1) | SG48687G (it) |
| SU (2) | SU1322979A3 (it) |
| YU (2) | YU43367B (it) |
| ZA (1) | ZA845490B (it) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4888348A (en) * | 1986-09-04 | 1989-12-19 | Ciba-Geigy Corporation | Substituted thioureas, isothioureas and carbodiimides |
| US6121260A (en) | 1997-07-03 | 2000-09-19 | Neurogen Corporation | Method of treating conditions susceptible to modulation of NPY receptors with diarylimidazole derivatives |
| US6887870B1 (en) | 1999-10-12 | 2005-05-03 | Bristol-Myers Squibb Company | Heterocyclic sodium/proton exchange inhibitors and method |
| DE60022386T2 (de) | 1999-12-16 | 2006-06-22 | Schering Corp. | Substituierte imidazole als neuropeptide y y5 rezeptor antagonisten |
| FR2917087B1 (fr) | 2007-06-05 | 2012-09-21 | Galderma Res & Dev | Nouveaux 4-phenyl-imidazole-2-thiones comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique. |
| US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1209431B (it) * | 1980-11-28 | 1989-07-16 | Angeli Inst Spa | Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione. |
-
1983
- 1983-07-18 IT IT8322110A patent/IT1206498B/it active
-
1984
- 1984-05-08 AT AT84200659T patent/ATE45149T1/de not_active IP Right Cessation
- 1984-05-08 EP EP84200659A patent/EP0131973B1/en not_active Expired
- 1984-05-08 DE DE8484200659T patent/DE3479212D1/de not_active Expired
- 1984-05-16 US US06/610,958 patent/US4649150A/en not_active Expired - Fee Related
- 1984-06-15 FI FI842432A patent/FI842432A/fi not_active Application Discontinuation
- 1984-07-02 YU YU1154/84A patent/YU43367B/xx unknown
- 1984-07-09 JP JP59142099A patent/JPS6038367A/ja active Pending
- 1984-07-11 PH PH30966A patent/PH21566A/en unknown
- 1984-07-16 KR KR1019840004177A patent/KR910000661B1/ko active IP Right Grant
- 1984-07-16 PL PL1984254625A patent/PL143732B1/pl unknown
- 1984-07-16 IL IL72417A patent/IL72417A/xx unknown
- 1984-07-16 DD DD84265319A patent/DD232696A5/de unknown
- 1984-07-16 PL PL1984248779A patent/PL143303B1/pl unknown
- 1984-07-17 ZA ZA845490A patent/ZA845490B/xx unknown
- 1984-07-17 GB GB08418149A patent/GB2149395B/en not_active Expired
- 1984-07-17 NZ NZ208920A patent/NZ208920A/en unknown
- 1984-07-17 ES ES534376A patent/ES534376A0/es active Granted
- 1984-07-17 ES ES534375A patent/ES534375A0/es active Granted
- 1984-07-17 NO NO842921A patent/NO162857C/no unknown
- 1984-07-17 HU HU842781A patent/HU193292B/hu not_active IP Right Cessation
- 1984-07-17 DK DK350084A patent/DK350084A/da not_active Application Discontinuation
- 1984-07-17 CA CA000459030A patent/CA1257274A/en not_active Expired
- 1984-07-17 SU SU843770847A patent/SU1322979A3/ru active
- 1984-07-17 GR GR75327A patent/GR79981B/el unknown
- 1984-07-18 PT PT78935A patent/PT78935B/pt unknown
- 1984-07-18 AU AU30800/84A patent/AU565292B2/en not_active Ceased
- 1984-07-18 CS CS845542A patent/CS244141B2/cs unknown
-
1985
- 1985-01-29 SU SU853844125A patent/SU1313345A3/ru active
-
1986
- 1986-06-26 YU YU1126/86A patent/YU43701B/xx unknown
-
1987
- 1987-06-03 SG SG486/87A patent/SG48687G/en unknown
- 1987-10-15 HK HK742/87A patent/HK74287A/xx unknown
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