IT8322540A0 - Procedimento per la preparazione di derivati della 2,4-diammino-5-benzil-pirimidina. - Google Patents

Procedimento per la preparazione di derivati della 2,4-diammino-5-benzil-pirimidina.

Info

Publication number
IT8322540A0
IT8322540A0 IT8322540A IT2254083A IT8322540A0 IT 8322540 A0 IT8322540 A0 IT 8322540A0 IT 8322540 A IT8322540 A IT 8322540A IT 2254083 A IT2254083 A IT 2254083A IT 8322540 A0 IT8322540 A0 IT 8322540A0
Authority
IT
Italy
Prior art keywords
diamino
benzyl
procedure
preparation
pyrimidine derivatives
Prior art date
Application number
IT8322540A
Other languages
English (en)
Other versions
IT1194372B (it
IT8322540A1 (it
Inventor
Ivan Peck
Janos Egri
Elemer Jakfalvi
Gyorgyi Kovanyi
Eva Furdyga
Istvan Simonyi
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of IT8322540A0 publication Critical patent/IT8322540A0/it
Publication of IT8322540A1 publication Critical patent/IT8322540A1/it
Application granted granted Critical
Publication of IT1194372B publication Critical patent/IT1194372B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/12—Saturated ethers containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Liquid Crystal Substances (AREA)
IT22540/83A 1982-08-13 1983-08-12 Procedimento per la preparazione di derivati della 2,4-diammino-5-benzil-pirimidina IT1194372B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU822604A HU188588B (en) 1982-08-13 1982-08-13 Process for the production of 2,4-diamino-5-benzyl-pyrimidine-derivatives

Publications (3)

Publication Number Publication Date
IT8322540A0 true IT8322540A0 (it) 1983-08-12
IT8322540A1 IT8322540A1 (it) 1985-02-12
IT1194372B IT1194372B (it) 1988-09-22

Family

ID=10960229

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22540/83A IT1194372B (it) 1982-08-13 1983-08-12 Procedimento per la preparazione di derivati della 2,4-diammino-5-benzil-pirimidina

Country Status (8)

Country Link
JP (1) JPS5993061A (it)
AT (1) AT387216B (it)
CH (1) CH657611A5 (it)
DE (1) DE3329226A1 (it)
GB (1) GB2125044B (it)
HU (1) HU188588B (it)
IT (1) IT1194372B (it)
SU (1) SU1222194A3 (it)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1720031A1 (de) * 1966-02-19 1972-08-03 Wellcome Found Biologisch wirksame 5-Benzylpyrimidin-Derivate und Verfahren zu ihrer Herstellung
CH598231A5 (it) * 1973-07-27 1978-04-28 Hoffmann La Roche
DK136470B (da) * 1973-11-08 1977-10-17 Hoffmann La Roche Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzylpyrimidinderivater eller salte deraf.
AR207671A1 (es) * 1975-01-03 1976-10-22 Prayon Procedimiento para la obtencion de un pigmento basico de oxido de hierro en forma alfa-fe2o3
DE2559752C3 (de) * 1975-10-17 1978-12-07 Ludwig Heumann & Co Gmbh, 8500 Nuernberg 2,4-Diamino-5-(3-methoxy-4-hydroxy-5-methyl-benzyl)-pyrimidin, Verfahren zu seiner Herstellung und diese Verbindung enthaltendes Arzneimittel
DE2546667C3 (de) * 1975-10-17 1978-10-12 Ludwig Heumann & Co Gmbh, 8500 Nuernberg 2,4-DiamüH»-5-(3-methoxy-4-hydroxy-5-halogenbenzyl)-pyrimidine, und diese Verbindungen enthaltende Arzneimittel
DE2617967C3 (de) * 1976-04-24 1978-11-02 Nordmark-Werke Gmbh, 2000 Hamburg Verfahren zur Herstellung von 2,4-Diamino-5-benzylpyrimidinen
DE2635765C3 (de) * 1976-08-09 1979-02-08 Ludwig Heumann & Co Gmbh, 8500 Nuernberg Verfahren zur Herstellung von 2,4-EMamino-5-(3',4'r5'-trimethoxybenzyl)-pyrimidin
IL57375A0 (en) * 1978-05-24 1979-09-30 Wellcome Found Benzylpyrimidines, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
HU188588B (en) 1986-04-28
GB2125044A (en) 1984-02-29
GB2125044B (en) 1985-09-18
SU1222194A3 (ru) 1986-03-30
CH657611A5 (de) 1986-09-15
JPS5993061A (ja) 1984-05-29
IT1194372B (it) 1988-09-22
GB8321618D0 (en) 1983-09-14
ATA290583A (de) 1988-05-15
DE3329226A1 (de) 1984-02-23
IT8322540A1 (it) 1985-02-12
AT387216B (de) 1988-12-27

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