IT7824650A0 - Derivati antrachinonici per il trattamento di artriti. - Google Patents
Derivati antrachinonici per il trattamento di artriti.Info
- Publication number
- IT7824650A0 IT7824650A0 IT7824650A IT2465078A IT7824650A0 IT 7824650 A0 IT7824650 A0 IT 7824650A0 IT 7824650 A IT7824650 A IT 7824650A IT 2465078 A IT2465078 A IT 2465078A IT 7824650 A0 IT7824650 A0 IT 7824650A0
- Authority
- IT
- Italy
- Prior art keywords
- arthritis
- treatment
- anthraquinone derivatives
- anthraquinone
- derivatives
- Prior art date
Links
- PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Natural products CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 title 1
- 150000004056 anthraquinones Chemical class 0.000 title 1
- 206010003246 arthritis Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C66/00—Quinone carboxylic acids
- C07C66/02—Anthraquinone carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/34—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having three rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ZA00761627A ZA761627B (en) | 1976-03-16 | 1976-03-16 | Improvements in or relating to the treatment of arthritis |
US05/773,406 US4244968A (en) | 1976-03-16 | 1977-03-01 | Treatment of arthritis and substances for use in such treatment |
GB10259/77A GB1578452A (en) | 1976-03-16 | 1977-03-10 | Pharmaceutical or veterinary formulations or compositions containing anthraquinone derivatives |
JP2915377A JPS52128229A (en) | 1976-03-16 | 1977-03-16 | Arthritis treating medical composition |
DE2760258A DE2760258C2 (it) | 1976-03-16 | 1977-03-16 | |
DE19772711493 DE2711493A1 (de) | 1976-03-16 | 1977-03-16 | Substanzen zur behandlung von arthritis |
IT24650/78A IT1098332B (it) | 1976-03-16 | 1978-06-16 | Derivati antrachinonici per il trattamento di artriti |
BE0/194914A BE875945A (fr) | 1976-03-16 | 1979-04-27 | Derives anthraquinoniques pour le traitement des arthrites |
US06/264,817 US4346103A (en) | 1976-03-16 | 1981-05-18 | Treatment for arthritis and substances for use in such treatment |
FR8113115A FR2508798B1 (fr) | 1976-03-16 | 1981-07-03 | Derives anthraquinoniques pour le traitement des arthrites |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ZA00761627A ZA761627B (en) | 1976-03-16 | 1976-03-16 | Improvements in or relating to the treatment of arthritis |
IT24650/78A IT1098332B (it) | 1976-03-16 | 1978-06-16 | Derivati antrachinonici per il trattamento di artriti |
FR8113115A FR2508798B1 (fr) | 1976-03-16 | 1981-07-03 | Derives anthraquinoniques pour le traitement des arthrites |
Publications (2)
Publication Number | Publication Date |
---|---|
IT7824650A0 true IT7824650A0 (it) | 1978-06-16 |
IT1098332B IT1098332B (it) | 1985-09-07 |
Family
ID=27251059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT24650/78A IT1098332B (it) | 1976-03-16 | 1978-06-16 | Derivati antrachinonici per il trattamento di artriti |
Country Status (8)
Country | Link |
---|---|
US (2) | US4244968A (it) |
JP (1) | JPS52128229A (it) |
BE (1) | BE875945A (it) |
DE (2) | DE2711493A1 (it) |
FR (1) | FR2508798B1 (it) |
GB (1) | GB1578452A (it) |
IT (1) | IT1098332B (it) |
ZA (1) | ZA761627B (it) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA761627B (en) * | 1976-03-16 | 1978-01-25 | C Friedmann | Improvements in or relating to the treatment of arthritis |
JPS58210009A (ja) * | 1983-04-11 | 1983-12-07 | プロツタ−・エス・ピ−・エ− | 関節炎治療薬組成物 |
IT1189097B (it) * | 1986-05-02 | 1988-01-28 | Proter Spa | Sali di diacetilreina e loro impiego terapeutico nel trattamento dell'artrosi |
IT1244886B (it) * | 1990-12-11 | 1994-09-13 | Gentili Ist Spa | Dicarbonati e uretani dell'acido 4,5-diidrossi- e 4,5,8-triidrossi- 9,10-diidro-9,10-diosso-2-antracencarbossilico ad azione terapeutica |
IT1244773B (it) * | 1991-03-12 | 1994-08-08 | Gentili Ist Spa | N-(4,5-diidrossi-e 4,5,8-triidrossi-9,10-diidro-9,10-diosso-2- antracen-il)carbonil) amminoacidi utilizzabili nella terapia delle affezioni osteoarticolari |
IT1247884B (it) * | 1991-05-03 | 1995-01-05 | Gentili Ist Spa | Esteri arilalchilici dell'acido 4,5 diidrossi-9,10-diidro-9,10-diosso 2-antracencarbossilico ad azione terapeutica |
DE4120990C2 (de) * | 1991-06-25 | 1995-07-27 | Madaus Ag | Verfahren zur Herstellung von Diacetylrhein |
US5393898A (en) * | 1991-06-25 | 1995-02-28 | Madaus Ag | Method of preparing diacetyl rhein |
DE4120989C2 (de) * | 1991-06-25 | 1995-07-27 | Madaus Ag | Verfahren zur Herstellung von Diacetylrhein |
CA2090743A1 (en) * | 1992-02-28 | 1993-08-29 | Michael Brunavs | Pharmaceutical compounds |
IT1264545B1 (it) * | 1993-07-30 | 1996-10-02 | Medidom Lab | Procedimento per la preparazione della diacereina |
GB9316912D0 (en) * | 1993-08-13 | 1993-09-29 | Lilly Industries Ltd | Pharmaceutical compounds |
GB9417102D0 (en) * | 1994-08-24 | 1994-10-12 | Lilly Industries Ltd | Pharmaceutical compounds |
CH689279A5 (fr) * | 1995-02-07 | 1999-01-29 | Steba Beheer Bv | Procédé de purification de la diacétylrhéine. |
US5652265A (en) * | 1995-03-29 | 1997-07-29 | Wisconsin Alumni Research Foundation | Production of rhein and rhein derivatives |
NL1003503C2 (nl) * | 1996-07-04 | 1998-01-07 | Negma Steba International Dev | Farmaceutische samenstelling voor orale toediening. |
IT1283771B1 (it) * | 1996-07-31 | 1998-04-30 | Medidom Lab | Procedimento per la preparazione di derivati della reina |
IT1283772B1 (it) * | 1996-07-31 | 1998-04-30 | Medidom Lab | Procedimento per la preparazione di reina e diacereina |
FR2757397B1 (fr) * | 1996-12-23 | 1999-03-05 | Mazal Pharma | Composition pharmaceutique a base de rheine ou de diacerheine a biodisponibilite amelioree |
AR026801A1 (es) * | 2000-01-12 | 2003-02-26 | Medidom Lab | Sustancias para uso en el tratamiento de la psoriasis |
US6610750B1 (en) * | 2000-09-15 | 2003-08-26 | Laboratoires Negma | Treatment of osteoarthritis |
US20020128317A1 (en) * | 2001-01-23 | 2002-09-12 | Laboratories Negma | Treatment of pathological conditions characterized by an increased IL-1 level |
US6797727B2 (en) * | 2001-07-16 | 2004-09-28 | Transition Therapeutics Inc. | Use of rhein or diacerhein compounds for the treatment or prevention of vascular diseases |
FR2842738B1 (fr) * | 2002-07-23 | 2006-02-10 | Negma Lerads | Utilisation d'une rheine pour la preparation d'un medicament pour le traitement de l'inflammation chronique, la prevention et le traitement du rejet des transplantations d'organes et de tissus |
DE10349722A1 (de) * | 2003-10-23 | 2005-06-16 | Beschorner, Katharina, Dr. | Zusammensetzung zur Arthrose-/Arthritisbehandlung, insbesondere von Gelenken |
GB0404953D0 (en) * | 2004-03-04 | 2004-04-07 | Arakis Ltd | Pro-drugs |
IL165365A0 (en) | 2004-11-24 | 2006-01-15 | Q Core Ltd | Finger-type peristaltic pump |
US7915380B2 (en) * | 2006-03-30 | 2011-03-29 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions, systems and methods for the diagnosis, prevention and treatment of disorders associated with azetidine-2-carboxylic acid |
EP2060562A1 (en) * | 2007-11-16 | 2009-05-20 | Laboratoire Medidom S.A. | Dioxoanthracene sulphonate derivatives |
TWI473610B (zh) * | 2008-10-28 | 2015-02-21 | Twi Biotechnology Inc | 包含雙醋瑞因(diacerein)之醫藥組合物 |
AR078101A1 (es) * | 2009-08-20 | 2011-10-12 | Anchen Lab Inc | Metodos para diagnosticar la diabetes y determinar la eficacia de tratamientos |
WO2011030350A1 (en) | 2009-09-08 | 2011-03-17 | Lupin Limited | Eco-friendly method for catalytic aerial oxidation of aloe-emodin to rheinal |
ITTO20110120A1 (it) | 2011-02-11 | 2012-08-12 | Icrom Spa | Un nuovo processo di purificazione per derivati antrachinonici |
US20150004229A1 (en) | 2011-12-27 | 2015-01-01 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Combined pharmaceutical formulation containing diacerein |
CN103641703B (zh) * | 2013-12-04 | 2015-09-09 | 西安近代化学研究所 | 1,8-二羟基蒽醌铜化合物及其制备方法和应用 |
EP2954895B1 (en) | 2014-06-11 | 2016-09-21 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical combinations of controlled release flurbiprofen and diacerein |
CN104262162B (zh) * | 2014-09-09 | 2016-12-07 | 西安近代化学研究所 | 一种1,8-二羟基-4,5-二硝基蒽醌铜化合物及其制备方法和应用 |
EP3988097A1 (en) | 2015-01-08 | 2022-04-27 | Selectimmune Pharma AB | Novel therapy |
MX2018011142A (es) | 2018-09-13 | 2019-10-10 | Federico Amezcua Amezcua | Combinacion farmaceutica sinergica de un inhibidor selectivo de la ciclooxigenasa 2 y un derivado de antraquinona. |
JP2022535595A (ja) | 2019-06-07 | 2022-08-09 | セレクティミューン ファーマ アクチエボラグ | 下部尿路における慢性炎症状態の処置および診断 |
US10717699B1 (en) * | 2020-04-09 | 2020-07-21 | Southwest University | Crotonyl alcohol cassic acid ester with antibacterial activity and a method of preparing the same |
GB202201139D0 (en) | 2022-01-28 | 2022-03-16 | Selectimmune Pharma Ab | Therapeutic agent |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1935928A (en) * | 1928-10-17 | 1933-11-21 | Gen Aniline Works Inc | Alpha-hydroxyanthrone derivatives and process of preparing them |
US2841596A (en) * | 1953-07-24 | 1958-07-01 | Pfizer & Co C | Cyclic ketones |
US2881173A (en) * | 1957-02-14 | 1959-04-07 | Hoffmann La Roche | Basic ethers of hydroxy anthraquinones |
US3983248A (en) * | 1968-11-21 | 1976-09-28 | Richardson-Merrell Inc. | Bis(aminoalkylsulfamoyl)anthraquinone antiviral agents |
US3974186A (en) * | 1970-05-14 | 1976-08-10 | Richardson-Merrell Inc. | Bis-basic ethers of 2,6- and 2,7-dihydroxyanthraquinones |
ZA714759B (en) | 1970-08-05 | 1972-04-26 | Allen & Hanburys Ltd | Anthraquinone derivatives |
US3873538A (en) * | 1970-08-05 | 1975-03-25 | Allen & Hanburys Ltd | Amino-9,10-dihydro-9,10-dioxo-2-anthroic acids |
US4035509A (en) * | 1974-04-22 | 1977-07-12 | Syntex (U.S.A.) Inc. | Methods and compositions for the use of 2-carboxy-5-oxo-5H-dibenzo[a,d]cycloheptenes, salts and esters thereof |
US4041173A (en) * | 1975-10-06 | 1977-08-09 | Syntex (U.S.A.) Inc. | 2-Carboxy-(7-,8- and 9-substituted)-5-oxo-5H-dibenzo (a,d) cycloheptenes and the corresponding 10,11-dihydro compounds |
ZA761627B (en) * | 1976-03-16 | 1978-01-25 | C Friedmann | Improvements in or relating to the treatment of arthritis |
-
1976
- 1976-03-16 ZA ZA00761627A patent/ZA761627B/xx unknown
-
1977
- 1977-03-01 US US05/773,406 patent/US4244968A/en not_active Expired - Lifetime
- 1977-03-10 GB GB10259/77A patent/GB1578452A/en not_active Expired
- 1977-03-16 JP JP2915377A patent/JPS52128229A/ja active Pending
- 1977-03-16 DE DE19772711493 patent/DE2711493A1/de active Granted
- 1977-03-16 DE DE2760258A patent/DE2760258C2/de not_active Expired
-
1978
- 1978-06-16 IT IT24650/78A patent/IT1098332B/it active
-
1979
- 1979-04-27 BE BE0/194914A patent/BE875945A/xx not_active IP Right Cessation
-
1981
- 1981-05-18 US US06/264,817 patent/US4346103A/en not_active Expired - Fee Related
- 1981-07-03 FR FR8113115A patent/FR2508798B1/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE2711493C2 (it) | 1987-12-03 |
BE875945A (fr) | 1979-08-16 |
IT1098332B (it) | 1985-09-07 |
ZA761627B (en) | 1978-01-25 |
DE2711493A1 (de) | 1977-10-06 |
DE2760258C2 (it) | 1989-12-21 |
US4346103A (en) | 1982-08-24 |
FR2508798B1 (fr) | 1986-04-25 |
US4244968A (en) | 1981-01-13 |
FR2508798A1 (fr) | 1983-01-07 |
JPS52128229A (en) | 1977-10-27 |
GB1578452A (en) | 1980-11-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ITCP | Complementary protection certificate |
Free format text: CCP 316 |
|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970630 |