FR2508798B1 - Derives anthraquinoniques pour le traitement des arthrites - Google Patents

Derives anthraquinoniques pour le traitement des arthrites

Info

Publication number
FR2508798B1
FR2508798B1 FR8113115A FR8113115A FR2508798B1 FR 2508798 B1 FR2508798 B1 FR 2508798B1 FR 8113115 A FR8113115 A FR 8113115A FR 8113115 A FR8113115 A FR 8113115A FR 2508798 B1 FR2508798 B1 FR 2508798B1
Authority
FR
France
Prior art keywords
arthrites
anthraquinon
derivatives
treatment
anthraquinon derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8113115A
Other languages
English (en)
Other versions
FR2508798A1 (fr
Inventor
Charles Aubrey Friedmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proter SpA
Original Assignee
Proter SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27251059&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2508798(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to ZA00761627A priority Critical patent/ZA761627B/xx
Priority to US05/773,406 priority patent/US4244968A/en
Priority to GB10259/77A priority patent/GB1578452A/en
Priority to JP2915377A priority patent/JPS52128229A/ja
Priority to DE2760258A priority patent/DE2760258C2/de
Priority to DE19772711493 priority patent/DE2711493A1/de
Priority to IT24650/78A priority patent/IT1098332B/it
Priority to BE0/194914A priority patent/BE875945A/fr
Priority to US06/264,817 priority patent/US4346103A/en
Application filed by Proter SpA filed Critical Proter SpA
Priority to FR8113115A priority patent/FR2508798B1/fr
Publication of FR2508798A1 publication Critical patent/FR2508798A1/fr
Publication of FR2508798B1 publication Critical patent/FR2508798B1/fr
Application granted granted Critical
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C66/00Quinone carboxylic acids
    • C07C66/02Anthraquinone carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00Preparation of quinones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00Quinones
    • C07C50/26Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/34Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having three rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8113115A 1976-03-16 1981-07-03 Derives anthraquinoniques pour le traitement des arthrites Expired FR2508798B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
ZA00761627A ZA761627B (en) 1976-03-16 1976-03-16 Improvements in or relating to the treatment of arthritis
US05/773,406 US4244968A (en) 1976-03-16 1977-03-01 Treatment of arthritis and substances for use in such treatment
GB10259/77A GB1578452A (en) 1976-03-16 1977-03-10 Pharmaceutical or veterinary formulations or compositions containing anthraquinone derivatives
DE2760258A DE2760258C2 (fr) 1976-03-16 1977-03-16
DE19772711493 DE2711493A1 (de) 1976-03-16 1977-03-16 Substanzen zur behandlung von arthritis
JP2915377A JPS52128229A (en) 1976-03-16 1977-03-16 Arthritis treating medical composition
IT24650/78A IT1098332B (it) 1976-03-16 1978-06-16 Derivati antrachinonici per il trattamento di artriti
BE0/194914A BE875945A (fr) 1976-03-16 1979-04-27 Derives anthraquinoniques pour le traitement des arthrites
US06/264,817 US4346103A (en) 1976-03-16 1981-05-18 Treatment for arthritis and substances for use in such treatment
FR8113115A FR2508798B1 (fr) 1976-03-16 1981-07-03 Derives anthraquinoniques pour le traitement des arthrites

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ZA00761627A ZA761627B (en) 1976-03-16 1976-03-16 Improvements in or relating to the treatment of arthritis
IT24650/78A IT1098332B (it) 1976-03-16 1978-06-16 Derivati antrachinonici per il trattamento di artriti
FR8113115A FR2508798B1 (fr) 1976-03-16 1981-07-03 Derives anthraquinoniques pour le traitement des arthrites

Publications (2)

Publication Number Publication Date
FR2508798A1 FR2508798A1 (fr) 1983-01-07
FR2508798B1 true FR2508798B1 (fr) 1986-04-25

Family

ID=27251059

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8113115A Expired FR2508798B1 (fr) 1976-03-16 1981-07-03 Derives anthraquinoniques pour le traitement des arthrites

Country Status (8)

Country Link
US (2) US4244968A (fr)
JP (1) JPS52128229A (fr)
BE (1) BE875945A (fr)
DE (2) DE2711493A1 (fr)
FR (1) FR2508798B1 (fr)
GB (1) GB1578452A (fr)
IT (1) IT1098332B (fr)
ZA (1) ZA761627B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2497761A1 (fr) 2011-02-11 2012-09-12 ICROM S.p.A. Un procédé de purification de composés anthraquinones

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA761627B (en) * 1976-03-16 1978-01-25 C Friedmann Improvements in or relating to the treatment of arthritis
JPS58210009A (ja) * 1983-04-11 1983-12-07 プロツタ−・エス・ピ−・エ− 関節炎治療薬組成物
IT1189097B (it) * 1986-05-02 1988-01-28 Proter Spa Sali di diacetilreina e loro impiego terapeutico nel trattamento dell'artrosi
IT1244886B (it) * 1990-12-11 1994-09-13 Gentili Ist Spa Dicarbonati e uretani dell'acido 4,5-diidrossi- e 4,5,8-triidrossi- 9,10-diidro-9,10-diosso-2-antracencarbossilico ad azione terapeutica
IT1244773B (it) * 1991-03-12 1994-08-08 Gentili Ist Spa N-(4,5-diidrossi-e 4,5,8-triidrossi-9,10-diidro-9,10-diosso-2- antracen-il)carbonil) amminoacidi utilizzabili nella terapia delle affezioni osteoarticolari
IT1247884B (it) * 1991-05-03 1995-01-05 Gentili Ist Spa Esteri arilalchilici dell'acido 4,5 diidrossi-9,10-diidro-9,10-diosso 2-antracencarbossilico ad azione terapeutica
US5393898A (en) * 1991-06-25 1995-02-28 Madaus Ag Method of preparing diacetyl rhein
DE4120989C2 (de) * 1991-06-25 1995-07-27 Madaus Ag Verfahren zur Herstellung von Diacetylrhein
DE4120990C2 (de) * 1991-06-25 1995-07-27 Madaus Ag Verfahren zur Herstellung von Diacetylrhein
EP0570091A1 (fr) * 1992-02-28 1993-11-18 Lilly Industries Limited Dérivés d'anthraquinone, procédés pour leur préparation et leur utilisation comme médicaments
IT1264545B1 (it) * 1993-07-30 1996-10-02 Medidom Lab Procedimento per la preparazione della diacereina
GB9316912D0 (en) * 1993-08-13 1993-09-29 Lilly Industries Ltd Pharmaceutical compounds
GB9417102D0 (en) 1994-08-24 1994-10-12 Lilly Industries Ltd Pharmaceutical compounds
CH689279A5 (fr) * 1995-02-07 1999-01-29 Steba Beheer Bv Procédé de purification de la diacétylrhéine.
US5652265A (en) * 1995-03-29 1997-07-29 Wisconsin Alumni Research Foundation Production of rhein and rhein derivatives
NL1003503C2 (nl) * 1996-07-04 1998-01-07 Negma Steba International Dev Farmaceutische samenstelling voor orale toediening.
IT1283771B1 (it) * 1996-07-31 1998-04-30 Medidom Lab Procedimento per la preparazione di derivati della reina
IT1283772B1 (it) * 1996-07-31 1998-04-30 Medidom Lab Procedimento per la preparazione di reina e diacereina
FR2757397B1 (fr) * 1996-12-23 1999-03-05 Mazal Pharma Composition pharmaceutique a base de rheine ou de diacerheine a biodisponibilite amelioree
AR026801A1 (es) * 2000-01-12 2003-02-26 Medidom Lab Sustancias para uso en el tratamiento de la psoriasis
US6610750B1 (en) * 2000-09-15 2003-08-26 Laboratoires Negma Treatment of osteoarthritis
US20020128317A1 (en) * 2001-01-23 2002-09-12 Laboratories Negma Treatment of pathological conditions characterized by an increased IL-1 level
US6797727B2 (en) * 2001-07-16 2004-09-28 Transition Therapeutics Inc. Use of rhein or diacerhein compounds for the treatment or prevention of vascular diseases
FR2842738B1 (fr) * 2002-07-23 2006-02-10 Negma Lerads Utilisation d'une rheine pour la preparation d'un medicament pour le traitement de l'inflammation chronique, la prevention et le traitement du rejet des transplantations d'organes et de tissus
DE10349722A1 (de) * 2003-10-23 2005-06-16 Beschorner, Katharina, Dr. Zusammensetzung zur Arthrose-/Arthritisbehandlung, insbesondere von Gelenken
GB0404953D0 (en) * 2004-03-04 2004-04-07 Arakis Ltd Pro-drugs
IL165365A0 (en) 2004-11-24 2006-01-15 Q Core Ltd Finger-type peristaltic pump
US7915380B2 (en) * 2006-03-30 2011-03-29 The Board Of Trustees Of The Leland Stanford Junior University Compositions, systems and methods for the diagnosis, prevention and treatment of disorders associated with azetidine-2-carboxylic acid
EP2060562A1 (fr) 2007-11-16 2009-05-20 Laboratoire Medidom S.A. Dérivés de sulfonate de dioxoanthracène
TWI473610B (zh) * 2008-10-28 2015-02-21 Twi Biotechnology Inc 包含雙醋瑞因(diacerein)之醫藥組合物
AR078101A1 (es) * 2009-08-20 2011-10-12 Anchen Lab Inc Metodos para diagnosticar la diabetes y determinar la eficacia de tratamientos
WO2011030350A1 (fr) 2009-09-08 2011-03-17 Lupin Limited Procédé respectueux de l'environnement permettant l'oxydation catalytique par l'air de l'aloé-émodine en rheinal
US20150004229A1 (en) 2011-12-27 2015-01-01 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Combined pharmaceutical formulation containing diacerein
CN103641703B (zh) * 2013-12-04 2015-09-09 西安近代化学研究所 1,8-二羟基蒽醌铜化合物及其制备方法和应用
EP2954895B1 (fr) 2014-06-11 2016-09-21 Sanovel Ilac Sanayi ve Ticaret A.S. Combinaisons pharmaceutiques de diacéréine et flurbiprofène à libération contrôlée
CN104262162B (zh) * 2014-09-09 2016-12-07 西安近代化学研究所 一种1,8-二羟基-4,5-二硝基蒽醌铜化合物及其制备方法和应用
US11013786B2 (en) 2015-01-08 2021-05-25 Selectimmune Pharma Ab Therapy
MX2018011142A (es) 2018-09-13 2019-10-10 Federico Amezcua Amezcua Combinacion farmaceutica sinergica de un inhibidor selectivo de la ciclooxigenasa 2 y un derivado de antraquinona.
US20220252625A1 (en) 2019-06-07 2022-08-11 Selectimmune Pharma Ab Treatment and diagnosis of chronic inflammatory conditions in the lower urinary tract
US10717699B1 (en) * 2020-04-09 2020-07-21 Southwest University Crotonyl alcohol cassic acid ester with antibacterial activity and a method of preparing the same
GB202201139D0 (en) 2022-01-28 2022-03-16 Selectimmune Pharma Ab Therapeutic agent

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1935928A (en) * 1928-10-17 1933-11-21 Gen Aniline Works Inc Alpha-hydroxyanthrone derivatives and process of preparing them
US2841596A (en) * 1953-07-24 1958-07-01 Pfizer & Co C Cyclic ketones
US2881173A (en) * 1957-02-14 1959-04-07 Hoffmann La Roche Basic ethers of hydroxy anthraquinones
US3983248A (en) * 1968-11-21 1976-09-28 Richardson-Merrell Inc. Bis(aminoalkylsulfamoyl)anthraquinone antiviral agents
US3974186A (en) * 1970-05-14 1976-08-10 Richardson-Merrell Inc. Bis-basic ethers of 2,6- and 2,7-dihydroxyanthraquinones
US3873538A (en) * 1970-08-05 1975-03-25 Allen & Hanburys Ltd Amino-9,10-dihydro-9,10-dioxo-2-anthroic acids
ZA714759B (en) 1970-08-05 1972-04-26 Allen & Hanburys Ltd Anthraquinone derivatives
US4035509A (en) * 1974-04-22 1977-07-12 Syntex (U.S.A.) Inc. Methods and compositions for the use of 2-carboxy-5-oxo-5H-dibenzo[a,d]cycloheptenes, salts and esters thereof
US4041173A (en) * 1975-10-06 1977-08-09 Syntex (U.S.A.) Inc. 2-Carboxy-(7-,8- and 9-substituted)-5-oxo-5H-dibenzo (a,d) cycloheptenes and the corresponding 10,11-dihydro compounds
ZA761627B (en) * 1976-03-16 1978-01-25 C Friedmann Improvements in or relating to the treatment of arthritis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2497761A1 (fr) 2011-02-11 2012-09-12 ICROM S.p.A. Un procédé de purification de composés anthraquinones

Also Published As

Publication number Publication date
BE875945A (fr) 1979-08-16
JPS52128229A (en) 1977-10-27
IT1098332B (it) 1985-09-07
FR2508798A1 (fr) 1983-01-07
DE2711493C2 (fr) 1987-12-03
ZA761627B (en) 1978-01-25
GB1578452A (en) 1980-11-05
US4346103A (en) 1982-08-24
US4244968A (en) 1981-01-13
DE2760258C2 (fr) 1989-12-21
IT7824650A0 (it) 1978-06-16
DE2711493A1 (de) 1977-10-06

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