IT1303683B1 - Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica. - Google Patents

Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica.

Info

Publication number
IT1303683B1
IT1303683B1 IT1998MI002330A ITMI982330A IT1303683B1 IT 1303683 B1 IT1303683 B1 IT 1303683B1 IT 1998MI002330 A IT1998MI002330 A IT 1998MI002330A IT MI982330 A ITMI982330 A IT MI982330A IT 1303683 B1 IT1303683 B1 IT 1303683B1
Authority
IT
Italy
Prior art keywords
dnacodifier
fragments
pharmaceutical composition
antigenic protein
action containing
Prior art date
Application number
IT1998MI002330A
Other languages
English (en)
Italian (it)
Inventor
Dino Parente
MASSIMO Anna Maria DI
Santis Rita De
Original Assignee
Menarini Ricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche Spa filed Critical Menarini Ricerche Spa
Publication of ITMI982330A0 publication Critical patent/ITMI982330A0/it
Priority to IT1998MI002330A priority Critical patent/IT1303683B1/it
Priority to TR2001/01141T priority patent/TR200101141T2/xx
Priority to AU11522/00A priority patent/AU1152200A/en
Priority to SK571-2001A priority patent/SK5712001A3/sk
Priority to HU0103784A priority patent/HUP0103784A2/hu
Priority to PCT/EP1999/007874 priority patent/WO2000025827A2/en
Priority to CN99812745A priority patent/CN1324406A/zh
Priority to EP99971329A priority patent/EP1124956A2/de
Priority to PL99348156A priority patent/PL348156A1/xx
Priority to CA002348745A priority patent/CA2348745A1/en
Priority to MXPA01004186A priority patent/MXPA01004186A/es
Priority to JP2000579265A priority patent/JP2002528519A/ja
Priority to EA200100395A priority patent/EA200100395A1/ru
Priority to BR9914892-7A priority patent/BR9914892A/pt
Priority to CZ20011521A priority patent/CZ20011521A3/cs
Priority to ARP990105316A priority patent/AR020927A1/es
Priority to PE1999001068A priority patent/PE20001287A1/es
Priority to CO99068636A priority patent/CO5231134A1/es
Publication of ITMI982330A1 publication Critical patent/ITMI982330A1/it
Application granted granted Critical
Publication of IT1303683B1 publication Critical patent/IT1303683B1/it
Priority to BG105458A priority patent/BG105458A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4727—Mucins, e.g. human intestinal mucin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001136—Cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT1998MI002330A 1998-10-30 1998-10-30 Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica. IT1303683B1 (it)

Priority Applications (19)

Application Number Priority Date Filing Date Title
IT1998MI002330A IT1303683B1 (it) 1998-10-30 1998-10-30 Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica.
MXPA01004186A MXPA01004186A (es) 1998-10-30 1999-10-18 Composicion farmaceutica, que contiene fragmentos de acido de desoxirribonucleico que codifica una proteina antigenica con efecto anti-tumoral.
EA200100395A EA200100395A1 (ru) 1998-10-30 1999-10-18 Фармацевтическая композиция, содержащая фрагменты днк, кодирующей антигенный белок, обладающая противоопухолевым действием
SK571-2001A SK5712001A3 (en) 1998-10-30 1999-10-18 Pharmaceutical composition
HU0103784A HUP0103784A2 (hu) 1998-10-30 1999-10-18 MUC-1-et kódoló DNS molekulák és ezek alkalmazása tumorellenes vakcinálásban
PCT/EP1999/007874 WO2000025827A2 (en) 1998-10-30 1999-10-18 Dna molecules encoding muc-1 and use thereof in tumor vaccination
CN99812745A CN1324406A (zh) 1998-10-30 1999-10-18 编码muc－1的dna分子及其在肿瘤疫苗中的用途
EP99971329A EP1124956A2 (de) 1998-10-30 1999-10-18 Pharmazeutische zusammensetzung, enthaltend fragmente einer antigenen, für ein protein kodierenden dna; ausgestattet mit einem antitumoreffekt
PL99348156A PL348156A1 (en) 1998-10-30 1999-10-18 Pharmaceutical composition, containing fragments of an antigenic protein encoding dna endowed with anti-tumor effect
CA002348745A CA2348745A1 (en) 1998-10-30 1999-10-18 Dna molecules encoding muc-1 and use thereof in tumor vaccination
TR2001/01141T TR200101141T2 (tr) 1998-10-30 1999-10-18 Antitümör etkiyi haiz antijenik proteini şifreleyen bir DNA'ya mahsus parçalar ihtiva eden farmasötik bileşim
JP2000579265A JP2002528519A (ja) 1998-10-30 1999-10-18 抗腫瘍効果を有する、抗原性タンパク質をコードしているｄｎａを含む医薬組成物
AU11522/00A AU1152200A (en) 1998-10-30 1999-10-18 Pharmaceutical composition, containing fragments of an antigenic protein encoding dna endowed with anti-tumor effect
BR9914892-7A BR9914892A (pt) 1998-10-30 1999-10-18 Composição farmacêutica, contendo fragmentos de um dna de codificação de proteìna antigênica dotado com efeito antitumor
CZ20011521A CZ20011521A3 (cs) 1998-10-30 1999-10-18 Farmaceutický prostředek obsahující fragmenty DNA kódující antigenní protein vykazující protinádorový účinek
ARP990105316A AR020927A1 (es) 1998-10-30 1999-10-21 Composicion farmaceutica que contiene fragmentos de adn codificador de una proteina antigenica dotada de efecto antitumoral
PE1999001068A PE20001287A1 (es) 1998-10-30 1999-10-22 Composicion farmaceutica que contiene fragmentos de adn codificador de una proteina antigenica con efecto antitumoral
CO99068636A CO5231134A1 (es) 1998-10-30 1999-10-29 Composicion farmaceutica que contiene fragmentos de adn codificador de una proteina antigenica con efecto antitumoral
BG105458A BG105458A (en) 1998-10-30 2001-04-20 Dna molecules encoding muc-1 and use thereof in tumor vaccination

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002330A IT1303683B1 (it) 1998-10-30 1998-10-30 Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica.

Publications (3)

Publication Number Publication Date
ITMI982330A0 ITMI982330A0 (it) 1998-10-30
ITMI982330A1 ITMI982330A1 (it) 2000-04-30
IT1303683B1 true IT1303683B1 (it) 2001-02-23

Family

ID=11380969

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998MI002330A IT1303683B1 (it) 1998-10-30 1998-10-30 Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica.

Country Status (19)

Country Link
EP (1) EP1124956A2 (de)
JP (1) JP2002528519A (de)
CN (1) CN1324406A (de)
AR (1) AR020927A1 (de)
AU (1) AU1152200A (de)
BG (1) BG105458A (de)
BR (1) BR9914892A (de)
CA (1) CA2348745A1 (de)
CO (1) CO5231134A1 (de)
CZ (1) CZ20011521A3 (de)
EA (1) EA200100395A1 (de)
HU (1) HUP0103784A2 (de)
IT (1) IT1303683B1 (de)
MX (1) MXPA01004186A (de)
PE (1) PE20001287A1 (de)
PL (1) PL348156A1 (de)
SK (1) SK5712001A3 (de)
TR (1) TR200101141T2 (de)
WO (1) WO2000025827A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548643B1 (en) 1994-11-16 2003-04-15 Austin Research Institute Antigen carbohydrate compounds and their use in immunotherapy
WO2001057068A1 (en) * 2000-02-01 2001-08-09 The Austin Research Institute Mucin-1 derived antigens and their use in immunotherapy
AU9263101A (en) * 2000-09-11 2002-03-26 Donald W Kufe Muc1 extracellular domain and cancer treatment compositions and methods derived therefrom
JP4276432B2 (ja) 2000-12-22 2009-06-10 ダナ−ファーバー キャンサー インスティテュート，インコーポレイテッド Ｍｕｃ１による細胞増殖調節方法
JP4616827B2 (ja) * 2003-03-24 2011-01-19 ザ スクリプス リサーチ インスティチュート 腫瘍成長に対するｄｎａワクチン及びその使用方法
US7696306B2 (en) 2003-07-11 2010-04-13 Board of Agents of the University of Nebraska Compositions and methods for preventing or treating cancer
US8129506B2 (en) 2003-10-24 2012-03-06 Genzyme Corporation Modulation of the interaction of MUC1 with MUC1 ligands
US7871784B2 (en) 2007-02-02 2011-01-18 Dana-Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of apoptosis by MUC1 and BH3-containing proapoptotic proteins
US7972870B2 (en) 2007-02-02 2011-07-05 Dana-Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of MUC1 by HSF1 and STAT3
CN106279435B (zh) * 2016-08-16 2019-06-07 新乡医学院 靶向VEGF与mucin1的抗肿瘤疫苗、编码基因、表达载体、表达工程菌及应用
CN113321724B (zh) * 2021-03-24 2022-02-01 深圳市新靶向生物科技有限公司 一种与食道癌驱动基因突变相关的抗原肽及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1262545B (it) * 1993-10-25 1996-07-02 Menarini Ricerche Sud S P A A Sistema di espressione per linee cellulari eucariotiche
CA2282300C (en) * 1997-02-24 2011-08-02 Therion Biologics Corporation Recombinant pox virus for immunization against muc1 tumor-associated antigen

Also Published As

Publication number Publication date
ITMI982330A1 (it) 2000-04-30
EA200100395A1 (ru) 2001-10-22
WO2000025827A3 (en) 2000-08-10
SK5712001A3 (en) 2002-04-04
CO5231134A1 (es) 2002-12-27
JP2002528519A (ja) 2002-09-03
AR020927A1 (es) 2002-06-05
MXPA01004186A (es) 2002-06-04
ITMI982330A0 (it) 1998-10-30
CN1324406A (zh) 2001-11-28
BG105458A (en) 2002-06-28
TR200101141T2 (tr) 2001-09-21
CZ20011521A3 (cs) 2001-10-17
WO2000025827A2 (en) 2000-05-11
HUP0103784A2 (hu) 2002-02-28
PE20001287A1 (es) 2000-12-07
EP1124956A2 (de) 2001-08-22
BR9914892A (pt) 2001-07-17
AU1152200A (en) 2000-05-22
CA2348745A1 (en) 2000-05-11
PL348156A1 (en) 2002-05-06

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