HUP0103784A2 - MUC-1-et kódoló DNS molekulák és ezek alkalmazása tumorellenes vakcinálásban - Google Patents

MUC-1-et kódoló DNS molekulák és ezek alkalmazása tumorellenes vakcinálásban

Info

Publication number
HUP0103784A2
HUP0103784A2 HU0103784A HUP0103784A HUP0103784A2 HU P0103784 A2 HUP0103784 A2 HU P0103784A2 HU 0103784 A HU0103784 A HU 0103784A HU P0103784 A HUP0103784 A HU P0103784A HU P0103784 A2 HUP0103784 A2 HU P0103784A2
Authority
HU
Hungary
Prior art keywords
dna molecules
molecules encoding
tumor vaccination
encoding muc
muc
Prior art date
Application number
HU0103784A
Other languages
English (en)
Hungarian (hu)
Inventor
Rita De Santis
Anna Maria Di Massimo
Dino Parente
Original Assignee
Menarini Ricerche S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche S.P.A. filed Critical Menarini Ricerche S.P.A.
Publication of HUP0103784A2 publication Critical patent/HUP0103784A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001136—Cytokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4727—Mucins, e.g. human intestinal mucin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU0103784A 1998-10-30 1999-10-18 MUC-1-et kódoló DNS molekulák és ezek alkalmazása tumorellenes vakcinálásban HUP0103784A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI002330A IT1303683B1 (it) 1998-10-30 1998-10-30 Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica.
PCT/EP1999/007874 WO2000025827A2 (en) 1998-10-30 1999-10-18 Dna molecules encoding muc-1 and use thereof in tumor vaccination

Publications (1)

Publication Number Publication Date
HUP0103784A2 true HUP0103784A2 (hu) 2002-02-28

Family

ID=11380969

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103784A HUP0103784A2 (hu) 1998-10-30 1999-10-18 MUC-1-et kódoló DNS molekulák és ezek alkalmazása tumorellenes vakcinálásban

Country Status (19)

Country Link
EP (1) EP1124956A2 (de)
JP (1) JP2002528519A (de)
CN (1) CN1324406A (de)
AR (1) AR020927A1 (de)
AU (1) AU1152200A (de)
BG (1) BG105458A (de)
BR (1) BR9914892A (de)
CA (1) CA2348745A1 (de)
CO (1) CO5231134A1 (de)
CZ (1) CZ20011521A3 (de)
EA (1) EA200100395A1 (de)
HU (1) HUP0103784A2 (de)
IT (1) IT1303683B1 (de)
MX (1) MXPA01004186A (de)
PE (1) PE20001287A1 (de)
PL (1) PL348156A1 (de)
SK (1) SK5712001A3 (de)
TR (1) TR200101141T2 (de)
WO (1) WO2000025827A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548643B1 (en) 1994-11-16 2003-04-15 Austin Research Institute Antigen carbohydrate compounds and their use in immunotherapy
WO2001057068A1 (en) * 2000-02-01 2001-08-09 The Austin Research Institute Mucin-1 derived antigens and their use in immunotherapy
AU9263101A (en) * 2000-09-11 2002-03-26 Donald W Kufe Muc1 extracellular domain and cancer treatment compositions and methods derived therefrom
JP4276432B2 (ja) 2000-12-22 2009-06-10 ダナ−ファーバー キャンサー インスティテュート，インコーポレイテッド Ｍｕｃ１による細胞増殖調節方法
JP4616827B2 (ja) * 2003-03-24 2011-01-19 ザ スクリプス リサーチ インスティチュート 腫瘍成長に対するｄｎａワクチン及びその使用方法
US7696306B2 (en) 2003-07-11 2010-04-13 Board of Agents of the University of Nebraska Compositions and methods for preventing or treating cancer
US8129506B2 (en) 2003-10-24 2012-03-06 Genzyme Corporation Modulation of the interaction of MUC1 with MUC1 ligands
US7871784B2 (en) 2007-02-02 2011-01-18 Dana-Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of apoptosis by MUC1 and BH3-containing proapoptotic proteins
US7972870B2 (en) 2007-02-02 2011-07-05 Dana-Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of MUC1 by HSF1 and STAT3
CN106279435B (zh) * 2016-08-16 2019-06-07 新乡医学院 靶向VEGF与mucin1的抗肿瘤疫苗、编码基因、表达载体、表达工程菌及应用
CN113321724B (zh) * 2021-03-24 2022-02-01 深圳市新靶向生物科技有限公司 一种与食道癌驱动基因突变相关的抗原肽及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1262545B (it) * 1993-10-25 1996-07-02 Menarini Ricerche Sud S P A A Sistema di espressione per linee cellulari eucariotiche
CA2282300C (en) * 1997-02-24 2011-08-02 Therion Biologics Corporation Recombinant pox virus for immunization against muc1 tumor-associated antigen

Also Published As

Publication number Publication date
ITMI982330A1 (it) 2000-04-30
EA200100395A1 (ru) 2001-10-22
WO2000025827A3 (en) 2000-08-10
SK5712001A3 (en) 2002-04-04
CO5231134A1 (es) 2002-12-27
JP2002528519A (ja) 2002-09-03
AR020927A1 (es) 2002-06-05
MXPA01004186A (es) 2002-06-04
ITMI982330A0 (it) 1998-10-30
CN1324406A (zh) 2001-11-28
BG105458A (en) 2002-06-28
TR200101141T2 (tr) 2001-09-21
CZ20011521A3 (cs) 2001-10-17
WO2000025827A2 (en) 2000-05-11
PE20001287A1 (es) 2000-12-07
EP1124956A2 (de) 2001-08-22
IT1303683B1 (it) 2001-02-23
BR9914892A (pt) 2001-07-17
AU1152200A (en) 2000-05-22
CA2348745A1 (en) 2000-05-11
PL348156A1 (en) 2002-05-06

Similar Documents

Publication Publication Date Title
IL132281A0 (en) Modified tnf alpha molecules dna encoding such modified tnf alpha molecules and vaccines comprising such modified tnf alpha molecules and dna
HUP9801216A3 (en) Dna molecules, preparation thereof and use thereof in gene therapy
AU4941101A (en) Novel prostate-specific or testis-specific nucleic acid molecules, polypeptides,and diagnostic and therapeutic methods
PL361887A1 (en) 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy
AP2002002690A0 (en) Antibody molecules having specificity for human tumor necrosis factor alphs and use thereof
SG54275A1 (en) Dna coding for decarbamylase improved in thermostability and use thereof
PL345243A1 (en) Gene coding for heliomicine and use thereof
HUP0103784A2 (hu) MUC-1-et kódoló DNS molekulák és ezek alkalmazása tumorellenes vakcinálásban
HUP9901035A3 (en) Parapoxviruses containing foreign dna, their production and their use in vaccines
HUP0300005A3 (en) Modified cytokines for use in cancer therapy
IL155613A0 (en) Novel human nucleic acid molecules and polypeptides emcoding a novel human ion channel expressed in spinal cord and brain
AU5874798A (en) Vaccination methods and molecules
AU2868601A (en) Biaryl compounds, their preparation and their use in therapy
IL146952A0 (en) Sulphonylamides and carboxamides and their use in asymmmetical catalysis
HK1042504A1 (en) Human cervical cancer 1 protooncogene and protein encoded therein
AU8308901A (en) Novel proteins and nucleic acids encoding same
EP1293568A4 (de) Protein und dessen dns
IL145775A0 (en) 13 transmembrane protein expressed in prostate cancer
IL144287A0 (en) Dna molecules encoding human clax proteins and their soluble fusion proteins
AU4328399A (en) Nucleic acid-cobalamin complexes and their use in gene therapy
EP1044216A4 (de) DNS-MOLEKÜLE, DIE FÜR DIE MENSCHLICHEN KERNREZPTOR-PROTEINE nNR7 UND nNR7-1 KODIEREN.
AU1926699A (en) Cathepsin dc proteins, dna encoding the proteins, and their use in human cancer prognosis
EP1331943A4 (de) Nukleinsäure-moleküle und polypeptide zur immunmodulation
AU2001269078A1 (en) Cyk-4 polypeptides, dna molecules encoding them and their use in screening methods
EP1142999A4 (de) Protein und dessen dns