IT1272990B - "composizione farmaceutica contenente carbazolone per il trattamento di emicrania e disturbi psicotici e relativo metodo di preparazione edapplicazione". - Google Patents
"composizione farmaceutica contenente carbazolone per il trattamento di emicrania e disturbi psicotici e relativo metodo di preparazione edapplicazione".Info
- Publication number
- IT1272990B IT1272990B ITRM940322A ITRM940322A IT1272990B IT 1272990 B IT1272990 B IT 1272990B IT RM940322 A ITRM940322 A IT RM940322A IT RM940322 A ITRM940322 A IT RM940322A IT 1272990 B IT1272990 B IT 1272990B
- Authority
- IT
- Italy
- Prior art keywords
- treatment
- pharmaceutical composition
- carbazolone
- headache
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Abstract
La invenzione si riferisce ad una composizione farmaceutica per somministrazione rettale comprendente 1, 2, 3, 9-tetraidro-9-metil-3[(2-metil-1H-imidazol-1-il) metil]-4H-carbazol-4-one sotto forma di sua base libera oppure di un suo solvato farmaceuticamente accettabile come ingrediente attivo, insieme con uno o più veicoli od eccipienti farmaceuticamente accettabili.Vengono anche descritti metodi per la produzione di tali composizioni e per il loro impiego nel trattamento di condizioni mediate dall'azione di 5-idrossitriptamina in corrispondenza di 5-HT3 recettori.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939310756A GB9310756D0 (en) | 1993-05-25 | 1993-05-25 | Compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM940322A0 ITRM940322A0 (it) | 1994-05-24 |
| ITRM940322A1 ITRM940322A1 (it) | 1995-11-24 |
| IT1272990B true IT1272990B (it) | 1997-07-01 |
Family
ID=10736089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITRM940322A IT1272990B (it) | 1993-05-25 | 1994-05-24 | "composizione farmaceutica contenente carbazolone per il trattamento di emicrania e disturbi psicotici e relativo metodo di preparazione edapplicazione". |
Country Status (38)
| Country | Link |
|---|---|
| US (1) | US5741806A (it) |
| EP (1) | EP0700290B1 (it) |
| JP (1) | JP2965703B2 (it) |
| KR (1) | KR100297212B1 (it) |
| CN (1) | CN1106194C (it) |
| AP (1) | AP544A (it) |
| AT (1) | ATE183643T1 (it) |
| AU (1) | AU680918B2 (it) |
| BE (1) | BE1007158A3 (it) |
| BR (1) | BR1100046A (it) |
| CA (1) | CA2162919C (it) |
| CO (1) | CO4230094A1 (it) |
| CY (1) | CY2411B1 (it) |
| CZ (1) | CZ291041B6 (it) |
| DE (1) | DE69420266T2 (it) |
| DK (1) | DK0700290T3 (it) |
| EC (1) | ECSP941088A (it) |
| ES (1) | ES2136198T3 (it) |
| FR (1) | FR2705569B1 (it) |
| GB (2) | GB9310756D0 (it) |
| GR (1) | GR3031669T3 (it) |
| HR (2) | HRP940315B1 (it) |
| HU (1) | HU227121B1 (it) |
| IE (1) | IE80632B1 (it) |
| IL (1) | IL109749A (it) |
| IS (1) | IS1868B (it) |
| IT (1) | IT1272990B (it) |
| MY (1) | MY111445A (it) |
| NO (1) | NO306448B1 (it) |
| NZ (1) | NZ267415A (it) |
| PE (1) | PE13395A1 (it) |
| PL (1) | PL175578B1 (it) |
| RU (1) | RU2132684C1 (it) |
| SA (1) | SA94150003B1 (it) |
| SG (1) | SG48119A1 (it) |
| SI (1) | SI0700290T1 (it) |
| WO (1) | WO1994027599A1 (it) |
| ZA (1) | ZA943593B (it) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1464333A3 (en) * | 1998-06-15 | 2004-12-15 | Sepracor Inc. | Use of optically pure (-) norcisapride in the treatment of apnea, bulimia, and other disorders |
| EP1468685A3 (en) * | 1998-06-15 | 2004-12-15 | Sepracor Inc. | Use of optically pure (+)-norcisapride for treating apnea, bulimia and other disorders |
| SK19062000A3 (sk) * | 1998-06-15 | 2001-07-10 | Sepracor, Inc. | Použitie (-)-norcisapridu alebo jeho farmaceuticky prijateľnej soli, v podstate bez jeho (+) stereoizoméru, na liečenie apnoe, bulímie a iných porúch |
| BR9911299A (pt) * | 1998-06-15 | 2001-03-13 | Sepracor Inc | Processos para tratar bulimia, para tratar distúrbios mediados por atividade vagal, para tratar sìndrome de intestino irritável, para tratar bradicardia ou bradiarritmia, para tratar asma, para tratar incontinência urinária, para tratar apnéia ou distúrbios de apnéia,ou distúrbios de apnéia, para prevenir ou controlar bulimia, distúrbios mediados por atividade vagal, sìndrome de intestino irritável, bradicardia ou bradiarritmia, asma, incontinência urinária, e, apnéia ou distúrbios da apnéia, em um paciente |
| US6362202B1 (en) | 1999-03-02 | 2002-03-26 | Sepracor Inc. | Methods and compositions using (−) norcisapride in combination with proton pump inhibitors or H2 receptor antagonists |
| US6353005B1 (en) | 1999-03-02 | 2002-03-05 | Sepracor, Inc. | Method and compositions using (+) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist |
| BR0112969A (pt) * | 2000-08-04 | 2004-06-22 | Dmi Biosciences Inc | Método de utilização de dicetopiperazinas e composições contendo-as |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4695578A (en) * | 1984-01-25 | 1987-09-22 | Glaxo Group Limited | 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances |
| DE3502508A1 (de) * | 1984-01-25 | 1985-08-14 | Glaxo Group Ltd., London | Heterocyclische verbindungen |
| GB8627909D0 (en) * | 1986-11-21 | 1986-12-31 | Glaxo Group Ltd | Medicaments |
| GB8816187D0 (en) * | 1988-07-07 | 1988-08-10 | Glaxo Group Ltd | Medicaments |
| US5166145A (en) * | 1990-09-10 | 1992-11-24 | Alza Corporation | Antiemetic therapy |
-
1993
- 1993-05-25 GB GB939310756A patent/GB9310756D0/en active Pending
-
1994
- 1994-05-17 EC EC1994001088A patent/ECSP941088A/es unknown
- 1994-05-17 SG SG1996007139A patent/SG48119A1/en unknown
- 1994-05-17 GB GB9409835A patent/GB2279008B/en not_active Expired - Lifetime
- 1994-05-19 IS IS4168A patent/IS1868B/is unknown
- 1994-05-20 MY MYPI94001305A patent/MY111445A/en unknown
- 1994-05-23 HR HR940315A patent/HRP940315B1/xx not_active IP Right Cessation
- 1994-05-23 PE PE1994242905A patent/PE13395A1/es not_active IP Right Cessation
- 1994-05-23 CO CO94021615A patent/CO4230094A1/es unknown
- 1994-05-23 IE IE940420A patent/IE80632B1/en not_active IP Right Cessation
- 1994-05-23 AP APAP/P/1994/000643A patent/AP544A/en active
- 1994-05-24 CZ CZ19953085A patent/CZ291041B6/cs not_active IP Right Cessation
- 1994-05-24 IT ITRM940322A patent/IT1272990B/it active IP Right Grant
- 1994-05-24 RU RU95122578A patent/RU2132684C1/ru active
- 1994-05-24 SI SI9430263T patent/SI0700290T1/xx unknown
- 1994-05-24 CA CA002162919A patent/CA2162919C/en not_active Expired - Lifetime
- 1994-05-24 WO PCT/EP1994/001652 patent/WO1994027599A1/en active IP Right Grant
- 1994-05-24 DE DE69420266T patent/DE69420266T2/de not_active Expired - Lifetime
- 1994-05-24 CN CN94192243A patent/CN1106194C/zh not_active Expired - Lifetime
- 1994-05-24 EP EP94918355A patent/EP0700290B1/en not_active Expired - Lifetime
- 1994-05-24 AU AU69709/94A patent/AU680918B2/en not_active Expired
- 1994-05-24 US US08/537,950 patent/US5741806A/en not_active Expired - Lifetime
- 1994-05-24 KR KR1019950705280A patent/KR100297212B1/ko not_active IP Right Cessation
- 1994-05-24 ZA ZA943593A patent/ZA943593B/xx unknown
- 1994-05-24 AT AT94918355T patent/ATE183643T1/de active
- 1994-05-24 IL IL10974994A patent/IL109749A/en not_active IP Right Cessation
- 1994-05-24 PL PL94311721A patent/PL175578B1/pl unknown
- 1994-05-24 HU HU9503375A patent/HU227121B1/hu unknown
- 1994-05-24 FR FR9406252A patent/FR2705569B1/fr not_active Expired - Lifetime
- 1994-05-24 NZ NZ267415A patent/NZ267415A/en not_active IP Right Cessation
- 1994-05-24 BE BE9400528A patent/BE1007158A3/fr not_active IP Right Cessation
- 1994-05-24 DK DK94918355T patent/DK0700290T3/da active
- 1994-05-24 ES ES94918355T patent/ES2136198T3/es not_active Expired - Lifetime
- 1994-05-24 JP JP7500204A patent/JP2965703B2/ja not_active Expired - Lifetime
- 1994-06-12 SA SA94150003A patent/SA94150003B1/ar unknown
-
1995
- 1995-11-24 NO NO954783A patent/NO306448B1/no not_active IP Right Cessation
-
1996
- 1996-09-19 BR BR1100046-5A patent/BR1100046A/pt active IP Right Grant
-
1997
- 1997-06-09 HR HR970315A patent/HRP970315A2/hr not_active Application Discontinuation
-
1999
- 1999-10-27 GR GR990402759T patent/GR3031669T3/el unknown
-
2000
- 2000-06-06 CY CY0000022A patent/CY2411B1/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970530 |