IT1245891B - Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali. - Google Patents

Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.

Info

Publication number
IT1245891B
IT1245891B ITBO910114A ITBO910114A IT1245891B IT 1245891 B IT1245891 B IT 1245891B IT BO910114 A ITBO910114 A IT BO910114A IT BO910114 A ITBO910114 A IT BO910114A IT 1245891 B IT1245891 B IT 1245891B
Authority
IT
Italy
Prior art keywords
gastro
resistant
salts
controlled release
pharmaceutical formulations
Prior art date
Application number
ITBO910114A
Other languages
English (en)
Italian (it)
Inventor
Egidio Marchi
Gianfranco Tamagnone
Leone Gabriele Rotini
Original Assignee
Alfa Wassermann Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wassermann Spa filed Critical Alfa Wassermann Spa
Publication of ITBO910114A0 publication Critical patent/ITBO910114A0/it
Priority to ITBO910114A priority Critical patent/IT1245891B/it
Priority to US07/861,462 priority patent/US5300300A/en
Priority to TW081102518A priority patent/TW215899B/zh
Priority to DE69213800T priority patent/DE69213800T2/de
Priority to ES92105717T priority patent/ES2091970T3/es
Priority to EP92105717A priority patent/EP0508312B1/en
Priority to JP4091131A priority patent/JP2509046B2/ja
Priority to CA002065652A priority patent/CA2065652C/en
Priority to KR1019920006053A priority patent/KR970005177B1/ko
Publication of ITBO910114A1 publication Critical patent/ITBO910114A1/it
Application granted granted Critical
Publication of IT1245891B publication Critical patent/IT1245891B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ITBO910114A 1991-04-12 1991-04-12 Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali. IT1245891B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ITBO910114A IT1245891B (it) 1991-04-12 1991-04-12 Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.
US07/861,462 US5300300A (en) 1991-04-12 1992-04-01 Controlled release gastroresistant pharmaceutical formulations for oral administration containing bile acids and their salts
ES92105717T ES2091970T3 (es) 1991-04-12 1992-04-02 Formulaciones farmaceuticas gastrorresistentes de liberacion controlada para administracion oral que contienen acidos biliares y sus sales.
DE69213800T DE69213800T2 (de) 1991-04-12 1992-04-02 Oral anzuwendende magensaftstabile Arzneimittel mit gesteuerter Wirkstoffabgabe enthaltend Gallensäuren und deren Salze
TW081102518A TW215899B (OSRAM) 1991-04-12 1992-04-02
EP92105717A EP0508312B1 (en) 1991-04-12 1992-04-02 Controlled release gastroresistant pharmaceutical formulations for oral administration containing bile acids and their salts
JP4091131A JP2509046B2 (ja) 1991-04-12 1992-04-10 胆汁酸およびその塩を含有する経口投与用の放出制御型胃液耐性製剤
CA002065652A CA2065652C (en) 1991-04-12 1992-04-10 Controlled release gastroresistant pharmaceutical formulations for oral administration containing bile acids and their salts
KR1019920006053A KR970005177B1 (ko) 1991-04-12 1992-04-11 담즙산과 그 염을 함유하는 경구용 방출제어 위내성 위약 의약 포뮬레이션

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITBO910114A IT1245891B (it) 1991-04-12 1991-04-12 Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.

Publications (3)

Publication Number Publication Date
ITBO910114A0 ITBO910114A0 (it) 1991-04-12
ITBO910114A1 ITBO910114A1 (it) 1992-10-12
IT1245891B true IT1245891B (it) 1994-10-25

Family

ID=11337392

Family Applications (1)

Application Number Title Priority Date Filing Date
ITBO910114A IT1245891B (it) 1991-04-12 1991-04-12 Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.

Country Status (9)

Country Link
US (1) US5300300A (OSRAM)
EP (1) EP0508312B1 (OSRAM)
JP (1) JP2509046B2 (OSRAM)
KR (1) KR970005177B1 (OSRAM)
CA (1) CA2065652C (OSRAM)
DE (1) DE69213800T2 (OSRAM)
ES (1) ES2091970T3 (OSRAM)
IT (1) IT1245891B (OSRAM)
TW (1) TW215899B (OSRAM)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9212511D0 (en) * 1992-06-12 1992-07-22 Cortecs Ltd Pharmaceutical compositions
IT1255968B (it) * 1992-11-27 1995-11-17 Composizioni farmaceutiche contenenti acido ursodesossicolico
IL109460A (en) 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE29717252U1 (de) * 1997-09-26 1998-02-19 Dr. Falk Pharma GmbH, 79108 Freiburg Arzneimittelkit aus einem Budesonid-haltigen und einem Ursodesoxycholsäure-haltigen Arzneimittel zur Behandlung von cholestatischen Lebererkrankungen
US20050158408A1 (en) * 1998-07-24 2005-07-21 Yoo Seo H. Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof
PT1113785E (pt) 1998-07-24 2005-08-31 Seo Hong Yoo Solucoes aquosas limpidas de acidos biliares
US7772220B2 (en) * 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
US7303768B2 (en) 1998-07-24 2007-12-04 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
KR100848344B1 (ko) * 2000-02-04 2008-07-25 유서홍 담즙산 함유 청정 수용액 제형의 제조
US6821931B2 (en) * 2002-03-05 2004-11-23 Alpine Mud Products Corporation Water-based drilling fluid additive containing talc and carrier
US20040241252A1 (en) * 2003-05-29 2004-12-02 Abney Christopher Charles Pharmaceutical compositions for oral administration comprising lithium carbonate, processes of making the same, and methods of administering the same
US7145125B2 (en) * 2003-06-23 2006-12-05 Advanced Optical Technologies, Llc Integrating chamber cone light using LED sources
US20070015796A1 (en) * 2003-09-26 2007-01-18 Smithkline Beecham Corporation Compositions and methods for treatment of fibrosis
US20050181047A1 (en) * 2004-02-18 2005-08-18 Jaime Romero Compositions and methods for timed release of water-soluble nutritional supplements
US7491263B2 (en) * 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
US8173627B2 (en) * 2004-08-30 2012-05-08 Seo Hong Yoo Neuroprotective effect of solubilized UDCA in focal ischemic model
WO2006044771A2 (en) * 2004-10-15 2006-04-27 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
CA2585471A1 (en) * 2004-11-01 2006-05-11 Seo Hong Yoo Methods and compositions for reducing neurodegeneration in amyotrophic lateral sclerosis
US20060275364A1 (en) * 2005-05-26 2006-12-07 Ahmed Salah U Flexible Solid Dosage Forms and Methods of Making and Using the Same
CA2673665C (en) * 2006-12-22 2017-03-21 Ironwood Pharmaceuticals, Inc. Method and compositions for treating esophageal disorders
KR101636958B1 (ko) * 2009-09-11 2016-07-06 주식회사 대웅제약 우루소데옥시콜린산-합성하이드로탈사이트-유드라짓 혼성체, 이를 함유하는 약학 조성물 및 그 제조방법
AU2012322323B2 (en) 2011-10-11 2016-04-21 Sun Pharmaceutical Industries Limited A gastroretentive dosage system and process of preparation thereof
US20170119680A1 (en) 2015-10-30 2017-05-04 R.P. Scherer Technologies, Llc Extended release film-coated capsules
BR112022001645A2 (pt) 2019-08-12 2022-05-03 Massachusetts Inst Technology Artigo configurado para liberação de um agente terapêutico, e, métodos para distribuir fármaco intestinal e para administrar um agente terapêutico
CN118217294B (zh) * 2023-08-08 2024-11-29 成都赛璟生物医药科技有限公司 一种熊去氧胆酸复合物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2340060A1 (de) * 1973-08-08 1975-02-20 Scherer Gmbh R P Magensaftresistente gelatinekapseln und verfahren zu deren herstellung
IT1101649B (it) 1978-12-15 1985-10-07 Lehner Ag Composizione farmaceutica ad azione prolungata contenente acidi biliari
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
IT1212141B (it) 1987-06-03 1989-11-08 So Ri Far S R L Composizioni farmaceutiche per la prevenzione e terapia della calcolosi delle vie biliari e della dispepsia biliare.

Also Published As

Publication number Publication date
CA2065652C (en) 1999-01-12
ES2091970T3 (es) 1996-11-16
DE69213800T2 (de) 1997-02-20
JP2509046B2 (ja) 1996-06-19
EP0508312B1 (en) 1996-09-18
KR970005177B1 (ko) 1997-04-14
JPH0597677A (ja) 1993-04-20
ITBO910114A0 (it) 1991-04-12
KR920019360A (ko) 1992-11-19
DE69213800D1 (de) 1996-10-24
TW215899B (OSRAM) 1993-11-11
ITBO910114A1 (it) 1992-10-12
US5300300A (en) 1994-04-05
EP0508312A1 (en) 1992-10-14
CA2065652A1 (en) 1992-10-13

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970423