ES2091970T3 - Formulaciones farmaceuticas gastrorresistentes de liberacion controlada para administracion oral que contienen acidos biliares y sus sales. - Google Patents
Formulaciones farmaceuticas gastrorresistentes de liberacion controlada para administracion oral que contienen acidos biliares y sus sales.Info
- Publication number
- ES2091970T3 ES2091970T3 ES92105717T ES92105717T ES2091970T3 ES 2091970 T3 ES2091970 T3 ES 2091970T3 ES 92105717 T ES92105717 T ES 92105717T ES 92105717 T ES92105717 T ES 92105717T ES 2091970 T3 ES2091970 T3 ES 2091970T3
- Authority
- ES
- Spain
- Prior art keywords
- gastrorresistent
- gastro
- oral administration
- controlled release
- biliar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000013270 controlled release Methods 0.000 title abstract 3
- 239000002253 acid Substances 0.000 title abstract 2
- 150000007513 acids Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title 1
- 239000008187 granular material Substances 0.000 abstract 3
- 239000007897 gelcap Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000006187 pill Substances 0.000 abstract 2
- 208000008439 Biliary Liver Cirrhosis Diseases 0.000 abstract 1
- 206010004659 Biliary cirrhosis Diseases 0.000 abstract 1
- 206010008635 Cholestasis Diseases 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 201000006549 dyspepsia Diseases 0.000 abstract 1
- 208000001130 gallstones Diseases 0.000 abstract 1
- 239000007903 gelatin capsule Substances 0.000 abstract 1
- JEGUKCSWCFPDGT-UHFFFAOYSA-N h2o hydrate Chemical compound O.O JEGUKCSWCFPDGT-UHFFFAOYSA-N 0.000 abstract 1
- 208000019423 liver disease Diseases 0.000 abstract 1
- 239000012053 oil suspension Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
FORMULACIONES FARMACEUTICAS GASTRORRESISTENTES DE LIBERACION CONTROLADA DE ADMINISTRACION ORAL QUE CONTIENEN ACIDOS BILIARES. FORMULACIONES FARMACEUTICAS DE LIBERACION CONTROLADA DE ADMINISTRACION ORAL REVESTIDAS CON UNA PELICULA GASTRORRESISTENTE ENTEROSOLUBLE, PREFERENTEMENTE SELECCIONADA DE GRANULOS GASTRORRESISTENTES, PASTILLAS GASTRORRESISTENTES, CAPSULAS DE GELATINA DURA GASTRORRESISTENTES QUE CONTIENEN POLVOS O GRANULOS O DOS O MAS PASTILLAS O SUSPENSIONES ACEITOSAS, CAPSULAS DE GELATINA BLANDA GASTRORRESISTENTES QUE CONTIENEN SUSPENSIONES ACEITOSAS Y CAPSULAS DE GELATINA DURA QUE CONTIENEN GRANULOS GASTRORRESISTENTES O DOS O MAS PASTILLAS GASTRORRESISTENTES, QUE CONTIENEN CANTIDADES TERAPEUTICAMENTE EFECTIVAS DE UNA MEZCLA DE LOS ACIDOS BILIARES Y DE SUS SALES CON METALES ALCALINOS O BASES ORGANICAS, LOS PROCESOS PARA SU PREPARACION Y EL USO TERAPEUTICO DE LAS MISMAS EN EL TRATAMIENTO DE CALCULOS BILIARES, DISPEPSIAS BILIARES, CIRROSIS BILIAR Y HEPATOPATIAS CRONICAS O COLESTATICAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITBO910114A IT1245891B (it) | 1991-04-12 | 1991-04-12 | Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2091970T3 true ES2091970T3 (es) | 1996-11-16 |
Family
ID=11337392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92105717T Expired - Lifetime ES2091970T3 (es) | 1991-04-12 | 1992-04-02 | Formulaciones farmaceuticas gastrorresistentes de liberacion controlada para administracion oral que contienen acidos biliares y sus sales. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5300300A (es) |
| EP (1) | EP0508312B1 (es) |
| JP (1) | JP2509046B2 (es) |
| KR (1) | KR970005177B1 (es) |
| CA (1) | CA2065652C (es) |
| DE (1) | DE69213800T2 (es) |
| ES (1) | ES2091970T3 (es) |
| IT (1) | IT1245891B (es) |
| TW (1) | TW215899B (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9212511D0 (en) * | 1992-06-12 | 1992-07-22 | Cortecs Ltd | Pharmaceutical compositions |
| IT1255968B (it) * | 1992-11-27 | 1995-11-17 | Composizioni farmaceutiche contenenti acido ursodesossicolico | |
| IL109460A (en) * | 1993-05-10 | 1998-03-10 | Euro Celtique Sa | Controlled release formulation comprising tramadol |
| KR100354702B1 (ko) * | 1993-11-23 | 2002-12-28 | 유로-셀티크 소시에떼 아노뉨 | 약학조성물의제조방법및서방형조성물 |
| US5891471A (en) * | 1993-11-23 | 1999-04-06 | Euro-Celtique, S.A. | Pharmaceutical multiparticulates |
| US5843480A (en) * | 1994-03-14 | 1998-12-01 | Euro-Celtique, S.A. | Controlled release diamorphine formulation |
| GB9422154D0 (en) | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
| US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| DE29717252U1 (de) * | 1997-09-26 | 1998-02-19 | Dr. Falk Pharma GmbH, 79108 Freiburg | Arzneimittelkit aus einem Budesonid-haltigen und einem Ursodesoxycholsäure-haltigen Arzneimittel zur Behandlung von cholestatischen Lebererkrankungen |
| JP4790123B2 (ja) | 1998-07-24 | 2011-10-12 | ヨー、セオ、ホン | 胆汁酸を有する透明水溶液型製剤の調剤 |
| US7772220B2 (en) * | 2004-10-15 | 2010-08-10 | Seo Hong Yoo | Methods and compositions for reducing toxicity of a pharmaceutical compound |
| US20050158408A1 (en) * | 1998-07-24 | 2005-07-21 | Yoo Seo H. | Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof |
| US7303768B2 (en) * | 1998-07-24 | 2007-12-04 | Seo Hong Yoo | Preparation of aqueous clear solution dosage forms with bile acids |
| DE19918325A1 (de) | 1999-04-22 | 2000-10-26 | Euro Celtique Sa | Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion |
| BR0108080A (pt) * | 2000-02-04 | 2006-02-07 | Seo Hong Yoo | Preparação de formas de dosagem de solução clara aquosa com ácidos biliares |
| US6821931B2 (en) * | 2002-03-05 | 2004-11-23 | Alpine Mud Products Corporation | Water-based drilling fluid additive containing talc and carrier |
| US20040241252A1 (en) * | 2003-05-29 | 2004-12-02 | Abney Christopher Charles | Pharmaceutical compositions for oral administration comprising lithium carbonate, processes of making the same, and methods of administering the same |
| US7145125B2 (en) * | 2003-06-23 | 2006-12-05 | Advanced Optical Technologies, Llc | Integrating chamber cone light using LED sources |
| WO2005032549A1 (en) * | 2003-09-26 | 2005-04-14 | Smithkline Beecham Corporation | Compositions and methods for treatment of fibrosis |
| US20050181047A1 (en) * | 2004-02-18 | 2005-08-18 | Jaime Romero | Compositions and methods for timed release of water-soluble nutritional supplements |
| US7491263B2 (en) * | 2004-04-05 | 2009-02-17 | Technology Innovation, Llc | Storage assembly |
| EP1789057B1 (en) * | 2004-08-30 | 2010-02-24 | Seo Hong Yoo | Neuroprotective effect of solubilized udca in focal ischemic model |
| EP1809330B1 (en) * | 2004-10-15 | 2011-04-27 | Seo Hong Yoo | Compositions for reducing toxicity of cisplatin, carboplatin, and oxaliplatin |
| US20060142241A1 (en) * | 2004-11-01 | 2006-06-29 | Yoo Seo H | Methods and compositions for reducing neurodegeneration in amyotrophic lateral sclerosis |
| US20060275364A1 (en) * | 2005-05-26 | 2006-12-07 | Ahmed Salah U | Flexible Solid Dosage Forms and Methods of Making and Using the Same |
| LT2124884T (lt) | 2006-12-22 | 2019-08-26 | Ironwood Pharmaceuticals, Inc. | Tulžies rūgščių sekvestrantus apimančios kompozicijos, skirtos stemplės sutrikimų gydymui |
| KR101636958B1 (ko) * | 2009-09-11 | 2016-07-06 | 주식회사 대웅제약 | 우루소데옥시콜린산-합성하이드로탈사이트-유드라짓 혼성체, 이를 함유하는 약학 조성물 및 그 제조방법 |
| WO2013054285A1 (en) | 2011-10-11 | 2013-04-18 | Ranbaxy Laboratories Limited | A gastroretentive dosage system and process of preparation thereof |
| US20170119680A1 (en) | 2015-10-30 | 2017-05-04 | R.P. Scherer Technologies, Llc | Extended release film-coated capsules |
| EP4013401A4 (en) | 2019-08-12 | 2023-07-12 | Massachusetts Institute of Technology | Articles and methods for administration of therapeutic agents |
| CN118217294B (zh) * | 2023-08-08 | 2024-11-29 | 成都赛璟生物医药科技有限公司 | 一种熊去氧胆酸复合物及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2340060A1 (de) * | 1973-08-08 | 1975-02-20 | Scherer Gmbh R P | Magensaftresistente gelatinekapseln und verfahren zu deren herstellung |
| IT1101649B (it) | 1978-12-15 | 1985-10-07 | Lehner Ag | Composizione farmaceutica ad azione prolungata contenente acidi biliari |
| GB2189699A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated acid-labile medicaments |
| IT1212141B (it) | 1987-06-03 | 1989-11-08 | So Ri Far S R L | Composizioni farmaceutiche per la prevenzione e terapia della calcolosi delle vie biliari e della dispepsia biliare. |
-
1991
- 1991-04-12 IT ITBO910114A patent/IT1245891B/it active IP Right Grant
-
1992
- 1992-04-01 US US07/861,462 patent/US5300300A/en not_active Expired - Fee Related
- 1992-04-02 EP EP92105717A patent/EP0508312B1/en not_active Expired - Lifetime
- 1992-04-02 DE DE69213800T patent/DE69213800T2/de not_active Expired - Fee Related
- 1992-04-02 ES ES92105717T patent/ES2091970T3/es not_active Expired - Lifetime
- 1992-04-02 TW TW081102518A patent/TW215899B/zh active
- 1992-04-10 JP JP4091131A patent/JP2509046B2/ja not_active Expired - Fee Related
- 1992-04-10 CA CA002065652A patent/CA2065652C/en not_active Expired - Fee Related
- 1992-04-11 KR KR1019920006053A patent/KR970005177B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2509046B2 (ja) | 1996-06-19 |
| TW215899B (es) | 1993-11-11 |
| JPH0597677A (ja) | 1993-04-20 |
| KR970005177B1 (ko) | 1997-04-14 |
| ITBO910114A0 (it) | 1991-04-12 |
| CA2065652A1 (en) | 1992-10-13 |
| IT1245891B (it) | 1994-10-25 |
| US5300300A (en) | 1994-04-05 |
| DE69213800T2 (de) | 1997-02-20 |
| EP0508312B1 (en) | 1996-09-18 |
| CA2065652C (en) | 1999-01-12 |
| DE69213800D1 (de) | 1996-10-24 |
| EP0508312A1 (en) | 1992-10-14 |
| KR920019360A (ko) | 1992-11-19 |
| ITBO910114A1 (it) | 1992-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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