FR2683146B1 - Compositions pharmaceutiques a liberation reglee de la substance medicamenteuse. - Google Patents

Compositions pharmaceutiques a liberation reglee de la substance medicamenteuse.

Info

Publication number
FR2683146B1
FR2683146B1 FR9212932A FR9212932A FR2683146B1 FR 2683146 B1 FR2683146 B1 FR 2683146B1 FR 9212932 A FR9212932 A FR 9212932A FR 9212932 A FR9212932 A FR 9212932A FR 2683146 B1 FR2683146 B1 FR 2683146B1
Authority
FR
France
Prior art keywords
pharmaceutical compositions
controlled release
drug substance
drug
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9212932A
Other languages
English (en)
Other versions
FR2683146A1 (fr
Inventor
Yogendra Dandiker
Derrick Huckle Paul
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919123044A external-priority patent/GB9123044D0/en
Priority claimed from GB919123026A external-priority patent/GB9123026D0/en
Priority claimed from GB929203364A external-priority patent/GB9203364D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FR2683146A1 publication Critical patent/FR2683146A1/fr
Application granted granted Critical
Publication of FR2683146B1 publication Critical patent/FR2683146B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2813Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
FR9212932A 1991-10-30 1992-10-29 Compositions pharmaceutiques a liberation reglee de la substance medicamenteuse. Expired - Lifetime FR2683146B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919123044A GB9123044D0 (en) 1991-10-30 1991-10-30 Compositions
GB919123026A GB9123026D0 (en) 1991-10-30 1991-10-30 Compositions
GB929203364A GB9203364D0 (en) 1992-02-18 1992-02-18 Compositions

Publications (2)

Publication Number Publication Date
FR2683146A1 FR2683146A1 (fr) 1993-05-07
FR2683146B1 true FR2683146B1 (fr) 1995-05-12

Family

ID=27265908

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9212932A Expired - Lifetime FR2683146B1 (fr) 1991-10-30 1992-10-29 Compositions pharmaceutiques a liberation reglee de la substance medicamenteuse.

Country Status (21)

Country Link
US (1) US5425950A (fr)
EP (1) EP0546593B1 (fr)
JP (1) JPH05194188A (fr)
KR (1) KR930007439A (fr)
AU (1) AU666880B2 (fr)
BE (1) BE1005490A3 (fr)
CA (1) CA2081709C (fr)
CH (1) CH685536A5 (fr)
CZ (1) CZ325792A3 (fr)
DE (1) DE69222006T2 (fr)
ES (1) ES2106818T3 (fr)
FR (1) FR2683146B1 (fr)
GB (1) GB2262445B (fr)
IE (1) IE922775A1 (fr)
IL (1) IL103593A0 (fr)
IT (1) IT1263253B (fr)
LU (1) LU88186A1 (fr)
MX (1) MX9206236A (fr)
NO (1) NO924183L (fr)
NZ (1) NZ244921A (fr)
TW (1) TW299236B (fr)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5609884A (en) * 1992-08-31 1997-03-11 G. D. Searle & Co. Controlled release naproxen sodium plus naproxen combination tablet
GB9401894D0 (en) 1994-02-01 1994-03-30 Rhone Poulenc Rorer Ltd New compositions of matter
JPH07223970A (ja) * 1994-02-10 1995-08-22 Tanabe Seiyaku Co Ltd 消化管内適所放出製剤
US6887461B1 (en) * 1998-10-26 2005-05-03 Genetics Institute, Llc Method of using IL-11 for treating mucositis
US6548084B2 (en) 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
JPH0940561A (ja) * 1995-08-02 1997-02-10 Fujitsukusu Kk 瀉下剤
US5922736A (en) * 1995-12-04 1999-07-13 Celegene Corporation Chronic, bolus administration of D-threo methylphenidate
US6486177B2 (en) * 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
US5837284A (en) * 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US8022095B2 (en) * 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
GB9706089D0 (en) * 1997-03-24 1997-05-14 Scherer Ltd R P Pharmaceutical composition
US6962997B1 (en) * 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
IN186245B (fr) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US6607751B1 (en) * 1997-10-10 2003-08-19 Intellipharamaceutics Corp. Controlled release delivery device for pharmaceutical agents incorporating microbial polysaccharide gum
AU2004222771B2 (en) * 1998-07-30 2006-09-21 Pfizer Inc. Prevention of Migraine Recurrence
GB9816556D0 (en) * 1998-07-30 1998-09-30 Pfizer Ltd Therapy
US6602521B1 (en) * 1998-09-29 2003-08-05 Impax Pharmaceuticals, Inc. Multiplex drug delivery system suitable for oral administration
US20080118556A1 (en) * 1998-11-02 2008-05-22 Elan Corporation, Plc Modified Release of Compositions Containing a Combination of Carbidopa, Levodopa and Entacapone
CN100444830C (zh) * 1998-11-02 2008-12-24 伊兰公司,Plc 多颗粒改进释放组合物
US20090149479A1 (en) * 1998-11-02 2009-06-11 Elan Pharma International Limited Dosing regimen
US20060240105A1 (en) * 1998-11-02 2006-10-26 Elan Corporation, Plc Multiparticulate modified release composition
PE20001302A1 (es) * 1998-11-27 2000-11-30 Hoffmann La Roche Preparaciones de una combinacion farmaceutica que contiene carvedilol e hidroclorotiazida
US6270807B1 (en) 1999-03-02 2001-08-07 L. Perrigo Company Taste-masked pharmaceutical composition
US6632451B2 (en) * 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
EP1064938A1 (fr) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Formes pharmaceutiques à libération contrôlée avec au moins une impulsion temporelle
US20040258750A1 (en) * 1999-06-28 2004-12-23 Gerard Alaux Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof
US6620431B1 (en) 2000-04-17 2003-09-16 Charles Signorino Shellac film coatings providing release at selected pH and method
US20020028240A1 (en) * 2000-04-17 2002-03-07 Toyohiro Sawada Timed-release compression-coated solid composition for oral administration
IT1318571B1 (it) * 2000-06-09 2003-08-27 Farmaka Srl Composizioni cosmetiche per la cura del cuoio capelluto e dei capelli.
US6500457B1 (en) 2000-08-14 2002-12-31 Peirce Management, Llc Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent
US20050020671A1 (en) * 2001-02-14 2005-01-27 Matilde Fernandez Ibanez Pharmaceutical formulation
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US20030072731A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing starch or dextrin
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
US20030104052A1 (en) * 2001-10-25 2003-06-05 Bret Berner Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
CA2409552A1 (fr) * 2001-10-25 2003-04-25 Depomed, Inc. Forme posologique orale pouvant etre retenue dans l'estomac dont la liberation est limitee a la partie inferieure du tube digestif
CN1620284B (zh) * 2001-12-24 2010-04-28 特瓦制药工业有限公司 含有用粉末或粒状材料的压缩环状体包鞘的有效成分片芯的剂型,及其生产工艺和工具
US20040052843A1 (en) * 2001-12-24 2004-03-18 Lerner E. Itzhak Controlled release dosage forms
EP1496867A1 (fr) * 2002-04-08 2005-01-19 Lavipharm Laboratories, Inc. Microparticules complexe-medicament et procedes et utilisations correspondants
BR0312795A (pt) * 2002-07-19 2005-05-10 Ranbaxy Lab Ltd Apresentação farmacêutica de sumatriptan, processo para sua preparação e método para tratar a enxaqueca
US7429619B2 (en) * 2002-08-02 2008-09-30 Mcneil Consumer Healthcare Polyacrylic film forming compositions
US20040068000A1 (en) * 2002-10-02 2004-04-08 Mintong Guo Compression coated tablets
US20080220074A1 (en) * 2002-10-04 2008-09-11 Elan Corporation Plc Gamma radiation sterilized nanoparticulate docetaxel compositions and methods of making same
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
DK1575566T3 (da) * 2002-12-26 2012-03-26 Pozen Inc Flerlagsdoseringsformer indeholdende naproxen og triptaner
US20060177506A1 (en) * 2003-03-17 2006-08-10 Shigeo Yanai Release control compositions
US20040241252A1 (en) * 2003-05-29 2004-12-02 Abney Christopher Charles Pharmaceutical compositions for oral administration comprising lithium carbonate, processes of making the same, and methods of administering the same
WO2004110492A2 (fr) * 2003-06-06 2004-12-23 Glaxo Group Limited Composition pharmaceutique
US7390503B1 (en) * 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
JP2007507491A (ja) * 2003-09-29 2007-03-29 シージェー コーポレーション 徐放性製剤
GB0400452D0 (en) * 2004-01-09 2004-02-11 Norton Healthcare Ltd A pharmaceutical composition
GB0403628D0 (en) * 2004-02-18 2004-03-24 Arrow Group Ltd Compression-coated tablets and the manufacture thereof
US20050239830A1 (en) * 2004-04-26 2005-10-27 Vikram Khetani Methods of diminishing co-abuse potential
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
WO2005115345A1 (fr) * 2004-05-28 2005-12-08 Imaginot Pty Ltd Systeme d'administration orale de compose therapeutique
US20060024361A1 (en) * 2004-07-28 2006-02-02 Isa Odidi Disintegrant assisted controlled release technology
WO2006010640A1 (fr) * 2004-07-29 2006-02-02 Sanofi-Aventis Comprime pharmaceutique multicouche pouvant liberer lentement des principes actifs dont la solubilite est fortement tributaire du ph
US20060024368A1 (en) * 2004-07-30 2006-02-02 Reza Fassihi Compressed composite delivery system for release-rate modulation of bioactives
US10624858B2 (en) * 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US20070269510A1 (en) * 2004-09-29 2007-11-22 Sudarshan Nimbalkar Solid Unit Dosage Forms of 5-Ht1 Agonist
EP1799264A2 (fr) * 2004-10-08 2007-06-27 Neuromolecular Pharmaceuticals Inc Methodes et compositions de traitement de la douleur de migraine
US20060121112A1 (en) * 2004-12-08 2006-06-08 Elan Corporation, Plc Topiramate pharmaceutical composition
KR20070087643A (ko) * 2004-12-09 2007-08-28 셀진 코포레이션 D-트레오 메틸페니데이트를 이용한 치료
KR20080007586A (ko) * 2005-04-12 2008-01-22 엘란 파마 인터내셔널 리미티드 세균감염증의 치료를 위한 세팔로스포린 함유 조절 방출조성물
US20100136106A1 (en) * 2005-06-08 2010-06-03 Gary Liversidge Modified Release Famciclovir Compositions
US9757455B2 (en) * 2005-11-28 2017-09-12 Johnson & Johnson Consumer Inc. Oral therapeutic compound delivery system
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
EP1993518A4 (fr) * 2006-03-06 2012-12-12 Pozen Inc Formes pharmaceutiques pour l'administration d'associations de medicaments
US9265732B2 (en) 2006-03-06 2016-02-23 Pozen Inc. Dosage forms for administering combinations of drugs
JP5457830B2 (ja) 2006-04-03 2014-04-02 オディディ,イサ オルガノゾル被膜を含む制御放出送達デバイス
EP2010162A4 (fr) * 2006-04-03 2013-01-09 Isa Odidi Composition d'administration de médicament
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
PL2049123T5 (pl) 2006-08-03 2017-09-29 Horizon Pharma Ag Leczenie choroby reumatoidalnej glukokortykoidem o opóźnionym uwalnianiu
EP2124556B1 (fr) 2006-10-09 2014-09-03 Charleston Laboratories, Inc. Compositions pharmaceutiques
KR100885029B1 (ko) * 2007-02-07 2009-02-23 지엘팜텍 주식회사 경구투여용 서방성 삼중정제
EP1970056A1 (fr) * 2007-03-15 2008-09-17 Polichem S.A. Formules de dosages à libération retardée/pulsatile spécifique au temps
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine
CA2749273C (fr) 2008-01-09 2018-09-04 Charleston Laboratories, Inc. Forme de dosage pharmaceutique oral renfermant un triptan et un antiemetique
EP3000462A1 (fr) * 2008-04-28 2016-03-30 Zogenix, Inc. Compositions inédites destinées au traitement de la migraine
TWI494108B (zh) * 2009-01-26 2015-08-01 Nitec Pharma Ag 糖皮質激素用以製備嚴重夜間氣喘用之於延遲釋放型的藥物之用途
NZ582836A (en) * 2009-01-30 2011-06-30 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid arthritis by improving signs and symptoms, showing major or complete clinical response and by preventing from joint damage
EP2403487A2 (fr) * 2009-03-04 2012-01-11 Fdc Limited Nouvelles formes galéniques orales à libération contrôlée pour médicaments hydrosolubles
CA2767576C (fr) 2009-07-08 2020-03-10 Charleston Laboratories Inc. Compositions pharmaceutiques refermant un antiemetique et un analgesiqueopioide
GB201003734D0 (en) 2010-03-05 2010-04-21 Univ Strathclyde Delayed prolonged drug delivery
GB201003731D0 (en) 2010-03-05 2010-04-21 Univ Strathclyde Immediate/delayed drug delivery
GB201003766D0 (en) 2010-03-05 2010-04-21 Univ Strathclyde Pulsatile drug release
PT2826467T (pt) 2010-12-22 2017-10-25 Purdue Pharma Lp Formas envolvidas de dosamento de libertação controlada resistentes à adulteração
NZ612996A (en) 2010-12-23 2015-05-29 Purdue Pharma Lp Tamper resistant solid oral dosage forms
EA201500742A1 (ru) 2013-02-05 2015-12-30 Пердью Фарма Л.П. Защищенные от нецелевого использования фармацевтические композиции
CA2903657A1 (fr) * 2013-02-27 2014-09-04 Shionogi & Co., Ltd. Derives d'indole et d'azaindole ayant chacun une activite d'activation d'ampk
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
KR20170020336A (ko) * 2014-06-13 2017-02-22 애버리 데니슨 코포레이션 의료용으로 사용되는 개선된 감압 접착제
JP2019507181A (ja) 2016-03-04 2019-03-14 チャールストン ラボラトリーズ,インコーポレイテッド 医薬組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892742A (en) * 1985-11-18 1990-01-09 Hoffmann-La Roche Inc. Controlled release compositions with zero order release
DE3720757A1 (de) * 1987-06-24 1989-01-05 Bayer Ag Dhp-manteltablette
DE3814532A1 (de) * 1988-04-29 1989-11-09 Bayer Ag Dhp-retard-zubereitung
US4880636A (en) * 1988-05-13 1989-11-14 Franz Robert M Film coated tablet of ranitidine HCl
US5032406A (en) * 1989-02-21 1991-07-16 Norwich Eaton Pharmaceuticals, Inc. Dual-action tablet
US5085865A (en) * 1989-04-12 1992-02-04 Warner-Lambert Company Sustained release pharmaceutical preparations containing an analgesic and a decongestant
GB9104890D0 (en) * 1991-03-08 1991-04-24 Glaxo Group Ltd Compositions

Also Published As

Publication number Publication date
CH685536A5 (fr) 1995-08-15
GB2262445A (en) 1993-06-23
EP0546593A1 (fr) 1993-06-16
GB9222662D0 (en) 1992-12-09
MX9206236A (es) 1993-04-01
IL103593A0 (en) 1993-03-15
KR930007439A (ko) 1993-05-20
CA2081709A1 (fr) 1993-05-01
DE69222006D1 (de) 1997-10-09
FR2683146A1 (fr) 1993-05-07
NO924183L (no) 1993-05-03
DE69222006T2 (de) 1998-01-22
GB2262445B (en) 1996-05-15
LU88186A1 (fr) 1993-05-17
ITRM920788A0 (it) 1992-10-29
IE922775A1 (en) 1993-05-05
AU2746992A (en) 1993-05-06
AU666880B2 (en) 1996-02-29
ITRM920788A1 (it) 1994-04-29
ES2106818T3 (es) 1997-11-16
NO924183D0 (no) 1992-10-29
IT1263253B (it) 1996-08-05
CA2081709C (fr) 2003-09-02
EP0546593B1 (fr) 1997-09-03
BE1005490A3 (fr) 1993-08-10
TW299236B (fr) 1997-03-01
US5425950A (en) 1995-06-20
JPH05194188A (ja) 1993-08-03
NZ244921A (en) 1995-04-27
CZ325792A3 (en) 1993-10-13

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