IT1263253B - Composizione farmaceutica di emissione regolata per la messa in liberta' di h2-antagonisti od agonisti od antagonisti di serotonina - Google Patents

Composizione farmaceutica di emissione regolata per la messa in liberta' di h2-antagonisti od agonisti od antagonisti di serotonina

Info

Publication number
IT1263253B
IT1263253B ITRM920788A ITRM920788A IT1263253B IT 1263253 B IT1263253 B IT 1263253B IT RM920788 A ITRM920788 A IT RM920788A IT RM920788 A ITRM920788 A IT RM920788A IT 1263253 B IT1263253 B IT 1263253B
Authority
IT
Italy
Prior art keywords
antagonists
pharmaceutical composition
release
agonists
layer
Prior art date
Application number
ITRM920788A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919123026A external-priority patent/GB9123026D0/en
Priority claimed from GB919123044A external-priority patent/GB9123044D0/en
Priority claimed from GB929203364A external-priority patent/GB9203364D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ITRM920788A0 publication Critical patent/ITRM920788A0/it
Publication of ITRM920788A1 publication Critical patent/ITRM920788A1/it
Application granted granted Critical
Publication of IT1263253B publication Critical patent/IT1263253B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2813—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Questa invenzione si riferisce ad una composizione farmaceutica di messa in libertà regolata comprendente:a) uno strato esterno comprendente un polimero idrofilo pH indipendente insieme con uno o più riempitivi;b) uno o più strati interni ognuno comprendente un ingrediente attivo;in cui lo strato esterno è gradualmente eliminato da una combinazione di scioglimento ed erosione successivi alla somministrazione e lo strato o strati interni vengono gradualmente eliminati da una combinazione di scioglimento ed erosione oppure si disintegrano rapidamente una volta esposti; e procedimenti per la sua preparazione. In particolare, l'invenzione si riferisce a composizione farmaceutiche per la messa in libertà regolata di H2-antagonisti oppure agonisti od antagonisti di serotonina.
ITRM920788A 1991-10-30 1992-10-29 Composizione farmaceutica di emissione regolata per la messa in liberta' di h2-antagonisti od agonisti od antagonisti di serotonina IT1263253B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919123026A GB9123026D0 (en) 1991-10-30 1991-10-30 Compositions
GB919123044A GB9123044D0 (en) 1991-10-30 1991-10-30 Compositions
GB929203364A GB9203364D0 (en) 1992-02-18 1992-02-18 Compositions

Publications (3)

Publication Number Publication Date
ITRM920788A0 ITRM920788A0 (it) 1992-10-29
ITRM920788A1 ITRM920788A1 (it) 1994-04-29
IT1263253B true IT1263253B (it) 1996-08-05

Family

ID=27265908

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM920788A IT1263253B (it) 1991-10-30 1992-10-29 Composizione farmaceutica di emissione regolata per la messa in liberta' di h2-antagonisti od agonisti od antagonisti di serotonina

Country Status (21)

Country Link
US (1) US5425950A (it)
EP (1) EP0546593B1 (it)
JP (1) JPH05194188A (it)
KR (1) KR930007439A (it)
AU (1) AU666880B2 (it)
BE (1) BE1005490A3 (it)
CA (1) CA2081709C (it)
CH (1) CH685536A5 (it)
CZ (1) CZ325792A3 (it)
DE (1) DE69222006T2 (it)
ES (1) ES2106818T3 (it)
FR (1) FR2683146B1 (it)
GB (1) GB2262445B (it)
IE (1) IE922775A1 (it)
IL (1) IL103593A0 (it)
IT (1) IT1263253B (it)
LU (1) LU88186A1 (it)
MX (1) MX9206236A (it)
NO (1) NO924183L (it)
NZ (1) NZ244921A (it)
TW (1) TW299236B (it)

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Also Published As

Publication number Publication date
IL103593A0 (en) 1993-03-15
GB2262445B (en) 1996-05-15
TW299236B (it) 1997-03-01
IE922775A1 (en) 1993-05-05
GB9222662D0 (en) 1992-12-09
ITRM920788A0 (it) 1992-10-29
CA2081709C (en) 2003-09-02
LU88186A1 (fr) 1993-05-17
GB2262445A (en) 1993-06-23
CZ325792A3 (en) 1993-10-13
DE69222006D1 (de) 1997-10-09
CA2081709A1 (en) 1993-05-01
ES2106818T3 (es) 1997-11-16
JPH05194188A (ja) 1993-08-03
ITRM920788A1 (it) 1994-04-29
AU2746992A (en) 1993-05-06
EP0546593B1 (en) 1997-09-03
CH685536A5 (fr) 1995-08-15
NZ244921A (en) 1995-04-27
MX9206236A (es) 1993-04-01
US5425950A (en) 1995-06-20
DE69222006T2 (de) 1998-01-22
FR2683146B1 (fr) 1995-05-12
AU666880B2 (en) 1996-02-29
NO924183D0 (no) 1992-10-29
KR930007439A (ko) 1993-05-20
BE1005490A3 (fr) 1993-08-10
NO924183L (no) 1993-05-03
FR2683146A1 (fr) 1993-05-07
EP0546593A1 (en) 1993-06-16

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