IT1219779B - Procedimento di purificazione per affinita' in cui si impiegano anticorpi monoclonali - Google Patents

Procedimento di purificazione per affinita' in cui si impiegano anticorpi monoclonali

Info

Publication number
IT1219779B
IT1219779B IT20550/83A IT2055083A IT1219779B IT 1219779 B IT1219779 B IT 1219779B IT 20550/83 A IT20550/83 A IT 20550/83A IT 2055083 A IT2055083 A IT 2055083A IT 1219779 B IT1219779 B IT 1219779B
Authority
IT
Italy
Prior art keywords
affinity
monoclonal antibodies
purifying process
purifying
monoclonal
Prior art date
Application number
IT20550/83A
Other languages
English (en)
Italian (it)
Other versions
IT8320550A0 (it
Inventor
Richard M Bartholomew
Daniel E Beidler
Gary S David
Original Assignee
Hybritech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybritech Inc filed Critical Hybritech Inc
Publication of IT8320550A0 publication Critical patent/IT8320550A0/it
Application granted granted Critical
Publication of IT1219779B publication Critical patent/IT1219779B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IT20550/83A 1982-04-12 1983-04-12 Procedimento di purificazione per affinita' in cui si impiegano anticorpi monoclonali IT1219779B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36778182A 1982-04-12 1982-04-12

Publications (2)

Publication Number Publication Date
IT8320550A0 IT8320550A0 (it) 1983-04-12
IT1219779B true IT1219779B (it) 1990-05-24

Family

ID=23448565

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20550/83A IT1219779B (it) 1982-04-12 1983-04-12 Procedimento di purificazione per affinita' in cui si impiegano anticorpi monoclonali

Country Status (11)

Country Link
EP (1) EP0105359A4 (enrdf_load_html_response)
AT (1) AT393386B (enrdf_load_html_response)
AU (1) AU622099B2 (enrdf_load_html_response)
CA (1) CA1209907A (enrdf_load_html_response)
CH (1) CH672028A5 (enrdf_load_html_response)
DK (1) DK192191A (enrdf_load_html_response)
ES (3) ES521371A0 (enrdf_load_html_response)
FI (1) FI88403C (enrdf_load_html_response)
GB (1) GB2128630B (enrdf_load_html_response)
IT (1) IT1219779B (enrdf_load_html_response)
WO (1) WO1983003678A1 (enrdf_load_html_response)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8328918D0 (en) * 1983-10-28 1983-11-30 Unilever Plc Alkaline phosphatase
GB8331071D0 (en) * 1983-11-22 1983-12-29 Karayiannis P Assay for dna/rna
US4666865A (en) * 1984-01-13 1987-05-19 Centocor, Inc. Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies
US4789631A (en) * 1984-02-17 1988-12-06 Synbiotics Corporation Immunoassay for anti-dirofilaria immitis antibody
GB8426468D0 (en) * 1984-10-19 1984-11-28 Technology Licence Co Ltd Monoclonal antibodies
AU5259786A (en) * 1985-01-30 1986-08-07 United States Of America, The Monoclonal antibodies against chlamydial genes specific lipopolysaccharide
US4859611A (en) * 1985-02-28 1989-08-22 Massachusetts Institute Of Technology Affinity column and process for detection of low molecular weight toxic substances
US4818687A (en) * 1985-02-28 1989-04-04 Massachusetts Institute Of Technology Affinity column and process for detection of low molecular weight toxic substances
IL75828A (en) * 1985-07-17 1991-06-10 Univ Ramot Immobilization by biologically active proteins
NZ218336A (en) * 1985-12-09 1991-08-27 Kirin Amgen Inc Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf)
US5175255A (en) * 1987-03-23 1992-12-29 Amgen Inc. Methods for purification of platelet-derived growth factor
US5190859A (en) * 1987-02-26 1993-03-02 Dana-Farber Cancer Institute, Inc. Purification of LFA-3
SE468653B (sv) * 1987-03-06 1993-02-22 Perstorp Biolytica Adsorbent foer isokratisk affinitetskromatografi
JPS6463599A (en) * 1987-05-01 1989-03-09 Xoma Corp Purification of immunoglobulin by selective anti-idiotype bond
DE3871799D1 (de) * 1987-07-14 1992-07-09 Univ Manchester Verfahren zur diagnose von infektionen, bei welchem lipopolyscaccharidantigene bestimmt werden.
CA1323567C (en) * 1987-10-05 1993-10-26 Gene R. Nathans Method for purification of antibodies
US5582862A (en) 1988-04-04 1996-12-10 General Hospital Corporation Antibodies that bind to α2-antiplasmin crosslinked to fibrin which do not inhibit plasma α2-antiplasmin
US5372812A (en) * 1988-04-04 1994-12-13 The General Hospital Corporation Composition and method for acceleration of clot lysis
AU741338B2 (en) * 1996-09-20 2001-11-29 Bristol-Myers Squibb Company Chimeric, humanized and single chain antibodies to alpha-2-antiplasmin
MY195714A (en) * 2008-04-11 2023-02-07 Chugai Pharmaceutical Co Ltd Antigen-Binding Molecule Capable of Binding to Two or More Antigen Molecules Repeatedly
RU2642318C2 (ru) 2010-11-30 2018-01-24 Чугаи Сейяку Кабусики Кайся Антигенсвязывающая молекула, способная многократно связываться с множеством антигенных молекул
JP6032818B2 (ja) 2011-02-25 2016-11-30 中外製薬株式会社 ＦｃγＲＩＩｂ特異的Ｆｃ抗体
WO2013047748A1 (ja) 2011-09-30 2013-04-04 中外製薬株式会社 複数の生理活性を有する抗原の消失を促進する抗原結合分子
KR20210074395A (ko) 2011-11-30 2021-06-21 추가이 세이야쿠 가부시키가이샤 면역 복합체를 형성하는 세포내로의 운반체（캐리어）를 포함하는 의약
SG10201710322VA (en) 2014-12-19 2018-02-27 Chugai Pharmaceutical Co Ltd Anti-c5 antibodies and methods of use
TWI808330B (zh) 2014-12-19 2023-07-11 日商中外製藥股份有限公司 抗肌抑素之抗體、含變異Fc區域之多胜肽及使用方法
JP7141336B2 (ja) 2015-12-25 2022-09-22 中外製薬株式会社 抗ミオスタチン抗体および使用方法
JP6527643B2 (ja) 2016-08-05 2019-06-05 中外製薬株式会社 Ｉｌ−８関連疾患の治療用又は予防用組成物
JP7191833B2 (ja) 2017-01-30 2022-12-19 中外製薬株式会社 抗スクレロスチン抗体およびその使用
CN110724204B (zh) * 2019-11-18 2021-10-22 广东菲鹏制药股份有限公司 Fc融合蛋白的纯化方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies
EP0059598B1 (en) * 1981-02-26 1985-07-17 Unilever Plc A process and apparatus for the recovery of immunoglobulines
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies

Also Published As

Publication number Publication date
FI88403B (fi) 1993-01-29
FI834530A0 (fi) 1983-12-09
ES8404858A1 (es) 1984-05-16
AT393386B (de) 1991-10-10
ES521371A0 (es) 1984-05-16
EP0105359A1 (en) 1984-04-18
DK192191D0 (da) 1991-11-26
ES528000A0 (es) 1985-08-01
ES8506902A1 (es) 1985-08-01
ATA901983A (de) 1991-03-15
ES8706964A1 (es) 1987-07-01
CA1209907A (en) 1986-08-19
WO1983003678A1 (en) 1983-10-27
FI834530L (fi) 1983-12-09
IT8320550A0 (it) 1983-04-12
CH672028A5 (enrdf_load_html_response) 1989-10-13
EP0105359A4 (en) 1984-08-20
ES528001A0 (es) 1987-07-01
AU7256987A (en) 1987-09-03
DK192191A (da) 1991-11-26
AU622099B2 (en) 1992-04-02
GB2128630B (en) 1986-08-28
FI88403C (fi) 1993-05-10
GB2128630A (en) 1984-05-02
GB8332644D0 (en) 1984-01-11

Similar Documents

Publication Publication Date Title
IT1219779B (it) Procedimento di purificazione per affinita' in cui si impiegano anticorpi monoclonali
GB8316001D0 (en) Monoclonal antibodies
GB8422653D0 (en) Monoclonal antibodies
GB8426467D0 (en) Monoclonal antibodies
GB8426463D0 (en) Monoclonal antibodies
GB8422650D0 (en) Monoclonal antibodies
FR2462513B1 (fr) Trieuse pour l'epuration de suspensions
GB8330331D0 (en) Monoclonal antibody
FI885956A7 (fi) Monoklonaalisia vasta-aineita keuhkokarsinoomaan
NO834535L (no) Fremgangsmaate for affinitetsrensing under anvendelse av monoklonale antistoffer.
GB8426461D0 (en) Monoclonal antibodies
GB8426464D0 (en) Monoclonal antibodies
GB8422649D0 (en) Monoclonal antibodies
GB8426468D0 (en) Monoclonal antibodies
GB8422651D0 (en) Monoclonal antibodies
GB8426459D0 (en) Monoclonal antibodies
GB8431171D0 (en) Monoclonal antibodies
GB8426465D0 (en) Monoclonal antibodies
GB8426470D0 (en) Monoclonal antibodies
IL71877A0 (en) Process for obtaining monoclonal antibodies
GB8426469D0 (en) Monoclonal antibodies
GB8426460D0 (en) Monoclonal antibodies
GB8416845D0 (en) Monoclonal antibodies
GB8419456D0 (en) Monoclonal antibodies
GB8426466D0 (en) Monoclonal antibodies