IT1196682B - Preparazione farmaceutica a base di n''-ciano-n-4-piridil-n'-1,2,2-trimetilpropilguanidina,particolarmente per il trattamento dell'ipertensione - Google Patents

Preparazione farmaceutica a base di n''-ciano-n-4-piridil-n'-1,2,2-trimetilpropilguanidina,particolarmente per il trattamento dell'ipertensione

Info

Publication number
IT1196682B
IT1196682B IT67131/84A IT6713184A IT1196682B IT 1196682 B IT1196682 B IT 1196682B IT 67131/84 A IT67131/84 A IT 67131/84A IT 6713184 A IT6713184 A IT 6713184A IT 1196682 B IT1196682 B IT 1196682B
Authority
IT
Italy
Prior art keywords
trimethylpropylguanidine
hypertension
cyan
pyridyl
treatment
Prior art date
Application number
IT67131/84A
Other languages
English (en)
Italian (it)
Other versions
IT8467131A0 (it
IT8467131A1 (it
Inventor
Erik Johannes Didriksen
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of IT8467131A0 publication Critical patent/IT8467131A0/it
Publication of IT8467131A1 publication Critical patent/IT8467131A1/it
Application granted granted Critical
Publication of IT1196682B publication Critical patent/IT1196682B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
IT67131/84A 1983-02-11 1984-02-13 Preparazione farmaceutica a base di n''-ciano-n-4-piridil-n'-1,2,2-trimetilpropilguanidina,particolarmente per il trattamento dell'ipertensione IT1196682B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK0589/83A DK58983D0 (da) 1983-02-11 1983-02-11 Farmaceutisk praeparat

Publications (3)

Publication Number Publication Date
IT8467131A0 IT8467131A0 (it) 1984-02-13
IT8467131A1 IT8467131A1 (it) 1985-08-13
IT1196682B true IT1196682B (it) 1988-11-25

Family

ID=8095276

Family Applications (1)

Application Number Title Priority Date Filing Date
IT67131/84A IT1196682B (it) 1983-02-11 1984-02-13 Preparazione farmaceutica a base di n''-ciano-n-4-piridil-n'-1,2,2-trimetilpropilguanidina,particolarmente per il trattamento dell'ipertensione

Country Status (15)

Country Link
US (1) US4600577A (enExample)
JP (1) JPS59155312A (enExample)
BE (1) BE898882A (enExample)
DE (1) DE3404595A1 (enExample)
DK (1) DK58983D0 (enExample)
ES (1) ES8608490A1 (enExample)
FR (1) FR2540727B1 (enExample)
GB (1) GB2134785B (enExample)
IE (1) IE56604B1 (enExample)
IT (1) IT1196682B (enExample)
NL (1) NL8400430A (enExample)
NZ (1) NZ207010A (enExample)
PH (1) PH21734A (enExample)
SE (1) SE447871B (enExample)
ZA (1) ZA84856B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS604120A (ja) * 1983-06-22 1985-01-10 Shionogi & Co Ltd 作用持続型ピナシジル製剤
US5286494A (en) * 1986-07-02 1994-02-15 Schering Aktiengesellschaft Medicinal agents with sustained action
US4861598A (en) * 1986-07-18 1989-08-29 Euroceltique, S.A. Controlled release bases for pharmaceuticals
EP0302595B1 (en) * 1987-07-07 1994-02-02 Beecham Group Plc Pinacidil for treatment of pulmonary hypertension or right heart failure
US5009894A (en) * 1988-03-07 1991-04-23 Baker Cummins Pharmaceuticals, Inc. Arrangement for and method of administering a pharmaceutical preparation
DE3822095A1 (de) * 1988-06-30 1990-01-04 Klinge Co Chem Pharm Fab Neue arzneimittelformulierung sowie verfahren zu deren herstellung
IT1246382B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
US5328697A (en) * 1992-02-10 1994-07-12 Mallinckrodt Veterinary, Inc. Compositions and processes for the sustained release of drugs
JP2002535353A (ja) 1999-01-29 2002-10-22 ロザン ファルマ ゲゼルシャフトミットベシュレンクテルハフツンク 医薬品組成物
US6210716B1 (en) * 1999-02-26 2001-04-03 Andrx Pharmaceuticals, Inc. Controlled release bupropion formulation
US6417207B1 (en) * 1999-05-12 2002-07-09 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
JP5502254B2 (ja) * 2001-01-31 2014-05-28 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング 少なくとも２種類の異なる被覆ペレット形から成る多粒子剤形
US8461187B2 (en) 2004-06-16 2013-06-11 Takeda Pharmaceuticals U.S.A., Inc. Multiple PPI dosage form
RU2010119041A (ru) 2007-10-12 2011-11-20 Такеда Фармасьютикалз Норт Америка, Инк. (Us) Способы лечения нарушений желудочно-кишечного тракта, независимого от потребления пищи

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1489879A (en) * 1974-12-20 1977-10-26 Leo Pharm Prod Ltd N'-cyano-n'-3-pyridylguanidines
JPS54129115A (en) * 1978-03-31 1979-10-06 Yasuyo Miyauchi Long acting amoxycilin preparation
FR2453639A1 (fr) * 1979-04-09 1980-11-07 Sanofi Sa Composition medicamenteuse a liberation programmee immediate-retard a base de naftidrofuryl
DE3000979A1 (de) * 1980-01-12 1981-07-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
FR2477015A1 (fr) * 1980-03-03 1981-09-04 Fabre Sa Pierre Composition pharmaceutique a base d'un alcaloide de l'ergot de seigle, a activite regulatrice sur le tonus vasculaire
JPS6056122B2 (ja) * 1980-05-21 1985-12-09 塩野義製薬株式会社 徐放性製剤
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
DE3127984A1 (de) * 1981-07-15 1983-02-03 Klinge Pharma GmbH, 8000 München Orale arzneimittel fuer die kariesprophylaxe

Also Published As

Publication number Publication date
IT8467131A0 (it) 1984-02-13
FR2540727A1 (fr) 1984-08-17
GB2134785A (en) 1984-08-22
ZA84856B (en) 1984-09-26
DE3404595C2 (enExample) 1993-04-29
PH21734A (en) 1988-02-10
GB2134785B (en) 1986-07-02
BE898882A (fr) 1984-08-10
IE840146L (en) 1984-08-11
DE3404595A1 (de) 1984-08-16
SE8400723L (sv) 1984-08-12
FR2540727B1 (fr) 1987-01-23
US4600577A (en) 1986-07-15
JPS59155312A (ja) 1984-09-04
IT8467131A1 (it) 1985-08-13
GB8403572D0 (en) 1984-03-14
ES8608490A1 (es) 1986-06-16
JPH0451528B2 (enExample) 1992-08-19
NL8400430A (nl) 1984-09-03
SE8400723D0 (sv) 1984-02-10
IE56604B1 (en) 1991-10-09
NZ207010A (en) 1987-06-30
SE447871B (sv) 1986-12-22
DK58983D0 (da) 1983-02-11
ES529660A0 (es) 1986-06-16

Similar Documents

Publication Publication Date Title
FI894711A7 (fi) Staongfoerpackning med applikatoryta.
IT8567478A0 (it) Composizione farmaceutica a base di difosfonati per il trattamento dell artrosi
IT8467131A0 (it) Preparazione farmaceutica a base di n"-ciano-n-4-piridil-n'-1,2,2-trime tilpropilguanidina,particolarmente per il trattamento dell'ipertensione
IT1184730B (it) Procedimento per produrre difenilammine oppure n,n'-difenil-fenilendiammine
IT8522425A0 (it) Procedimento di sintesi dell'amikacina.
IT8521498A0 (it) Isoindolinil-alchil-piperazine adattivita' farmaceutica.
ITMI913465A1 (it) Procedimento per la depurazione dell'1, 1, 1-trifluoro-2-fluoroetano
FR2576635B1 (fr) Plate-forme d'aube.
IT1230068B (it) Procedimento per la preparazione di n sulfoniluree.
IT1216560B (it) Procedimento per la preparazione di bis(2,2,6,6_tetrametil_4_piperidil)ammina.
IT1209577B (it) Sintesi dell'aspartame.
IT8922246A0 (it) Procedimento di preparazione di 3-ciano-3,5,5'-trimetil-1-cicloesanone
IT1187681B (it) Metodo per la preparazione di 3,4-epossibutirrati alchilici
IT8021542A0 (it) Procedimento per la preparazione di idrossiderivati dell'isopropilammino-pirimidina (attraverso una base minerale).
IT8520234A0 (it) Composizione farmaceutiche adattivita' dopominergica.
IT1213320B (it) Composizione farmaceutica orale a base di ubichinoni.
IT1212097B (it) Sintesi dell'aspartame.
IT1190604B (it) Procedimento per la preparazione di 4,4-dialchil-2-azetidinoni
IT1208537B (it) Processo per la preparazione dell'isosorbide-5-monoidrato.
IT8321080A0 (it) Procedimento per la preparazione dell'estere metilico di alfa-l-aspartil-l-fenil-alanina.
IT1217950B (it) Sali di (r,s) 3 (4 fenil 1 piperazinil) 1,2 propandtolo
IT8719475A0 (it) Procedimento per la preparazione di encainide.
IT8323029A0 (it) Processo per la sintesi di copolimeri a blocchi a base di pivalolattone.
FR2605885B1 (fr) Association medicamenteuse a base d'un inhibiteur calcique
IT1222698B (it) Composti a base di 7-ossabiciclo (2.2.1) eptano aventi attivita' farmaceutica

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19990226