ES529660A0 - Procedimiento de obtencion de una preparacion farmaceutica en forma de liberacion lenta y que comprende pinacidil (n'-ciano-n-4-piridil-n'-1, 2, 2-trimetil-propilguanidina), opcionalmente junto con otros componentes - Google Patents

Procedimiento de obtencion de una preparacion farmaceutica en forma de liberacion lenta y que comprende pinacidil (n'-ciano-n-4-piridil-n'-1, 2, 2-trimetil-propilguanidina), opcionalmente junto con otros componentes

Info

Publication number
ES529660A0
ES529660A0 ES529660A ES529660A ES529660A0 ES 529660 A0 ES529660 A0 ES 529660A0 ES 529660 A ES529660 A ES 529660A ES 529660 A ES529660 A ES 529660A ES 529660 A0 ES529660 A0 ES 529660A0
Authority
ES
Spain
Prior art keywords
piridil
propylguanidine
ciano
pinacidil
trimethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES529660A
Other languages
English (en)
Other versions
ES8608490A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo Pharma AS
Original Assignee
Leo Pharmaceutical Products Ltd AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharmaceutical Products Ltd AS filed Critical Leo Pharmaceutical Products Ltd AS
Publication of ES8608490A1 publication Critical patent/ES8608490A1/es
Publication of ES529660A0 publication Critical patent/ES529660A0/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
ES529660A 1983-02-11 1984-02-10 Procedimiento de obtencion de una preparacion farmaceutica en forma de liberacion lenta y que comprende pinacidil (n'-ciano-n-4-piridil-n'-1, 2, 2-trimetil-propilguanidina), opcionalmente junto con otros componentes Expired ES8608490A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK0589/83A DK58983D0 (da) 1983-02-11 1983-02-11 Farmaceutisk praeparat

Publications (2)

Publication Number Publication Date
ES8608490A1 ES8608490A1 (es) 1986-06-16
ES529660A0 true ES529660A0 (es) 1986-06-16

Family

ID=8095276

Family Applications (1)

Application Number Title Priority Date Filing Date
ES529660A Expired ES8608490A1 (es) 1983-02-11 1984-02-10 Procedimiento de obtencion de una preparacion farmaceutica en forma de liberacion lenta y que comprende pinacidil (n'-ciano-n-4-piridil-n'-1, 2, 2-trimetil-propilguanidina), opcionalmente junto con otros componentes

Country Status (15)

Country Link
US (1) US4600577A (es)
JP (1) JPS59155312A (es)
BE (1) BE898882A (es)
DE (1) DE3404595A1 (es)
DK (1) DK58983D0 (es)
ES (1) ES8608490A1 (es)
FR (1) FR2540727B1 (es)
GB (1) GB2134785B (es)
IE (1) IE56604B1 (es)
IT (1) IT1196682B (es)
NL (1) NL8400430A (es)
NZ (1) NZ207010A (es)
PH (1) PH21734A (es)
SE (1) SE447871B (es)
ZA (1) ZA84856B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS604120A (ja) * 1983-06-22 1985-01-10 Shionogi & Co Ltd 作用持続型ピナシジル製剤
US5286494A (en) * 1986-07-02 1994-02-15 Schering Aktiengesellschaft Medicinal agents with sustained action
US4861598A (en) * 1986-07-18 1989-08-29 Euroceltique, S.A. Controlled release bases for pharmaceuticals
EP0579260A1 (en) * 1987-07-07 1994-01-19 Beecham Group Plc Use of a vasodilator for the treatment of pulmonary hypertension and/or right heart failure-related conditions
US5009894A (en) * 1988-03-07 1991-04-23 Baker Cummins Pharmaceuticals, Inc. Arrangement for and method of administering a pharmaceutical preparation
DE3822095A1 (de) * 1988-06-30 1990-01-04 Klinge Co Chem Pharm Fab Neue arzneimittelformulierung sowie verfahren zu deren herstellung
IT1246382B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
US5328697A (en) * 1992-02-10 1994-07-12 Mallinckrodt Veterinary, Inc. Compositions and processes for the sustained release of drugs
MXPA01007463A (es) 1999-01-29 2002-06-04 Losan Pharma Gmbh Composiciones farmaceuticas.
US6210716B1 (en) * 1999-02-26 2001-04-03 Andrx Pharmaceuticals, Inc. Controlled release bupropion formulation
AU4841700A (en) 1999-05-12 2000-11-21 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
ATE380022T1 (de) * 2001-01-31 2007-12-15 Evonik Roehm Gmbh Multipartikuläre arzneiform, enthaltend mindestens zwei unterschiedlich überzogene pelletformen
EP1768668A2 (en) 2004-06-16 2007-04-04 Tap Pharmaceutical Products, Inc. Multiple ppi dosage form
RU2013106514A (ru) 2007-10-12 2015-03-10 Такеда Фармасьютикалз Норт Америка, Инк. Способы лечения нарушений желудочно-кишечного тракта независимо от потребления пищи

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1489879A (en) * 1974-12-20 1977-10-26 Leo Pharm Prod Ltd N'-cyano-n'-3-pyridylguanidines
JPS54129115A (en) * 1978-03-31 1979-10-06 Yasuyo Miyauchi Long acting amoxycilin preparation
FR2453639A1 (fr) * 1979-04-09 1980-11-07 Sanofi Sa Composition medicamenteuse a liberation programmee immediate-retard a base de naftidrofuryl
DE3000979A1 (de) * 1980-01-12 1981-07-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
FR2477015A1 (fr) * 1980-03-03 1981-09-04 Fabre Sa Pierre Composition pharmaceutique a base d'un alcaloide de l'ergot de seigle, a activite regulatrice sur le tonus vasculaire
JPS6056122B2 (ja) * 1980-05-21 1985-12-09 塩野義製薬株式会社 徐放性製剤
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
DE3127984A1 (de) * 1981-07-15 1983-02-03 Klinge Pharma GmbH, 8000 München Orale arzneimittel fuer die kariesprophylaxe

Also Published As

Publication number Publication date
SE8400723L (sv) 1984-08-12
ES8608490A1 (es) 1986-06-16
PH21734A (en) 1988-02-10
DK58983D0 (da) 1983-02-11
DE3404595C2 (es) 1993-04-29
ZA84856B (en) 1984-09-26
DE3404595A1 (de) 1984-08-16
US4600577A (en) 1986-07-15
IE56604B1 (en) 1991-10-09
SE8400723D0 (sv) 1984-02-10
IE840146L (en) 1984-08-11
NZ207010A (en) 1987-06-30
FR2540727A1 (fr) 1984-08-17
NL8400430A (nl) 1984-09-03
GB2134785A (en) 1984-08-22
IT8467131A0 (it) 1984-02-13
GB2134785B (en) 1986-07-02
BE898882A (fr) 1984-08-10
GB8403572D0 (en) 1984-03-14
JPS59155312A (ja) 1984-09-04
FR2540727B1 (fr) 1987-01-23
SE447871B (sv) 1986-12-22
IT1196682B (it) 1988-11-25
JPH0451528B2 (es) 1992-08-19

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