IT1167937B - Composti collegati alla bestatina come immunopotenziatore - Google Patents

Composti collegati alla bestatina come immunopotenziatore

Info

Publication number
IT1167937B
IT1167937B IT09465/81A IT946581A IT1167937B IT 1167937 B IT1167937 B IT 1167937B IT 09465/81 A IT09465/81 A IT 09465/81A IT 946581 A IT946581 A IT 946581A IT 1167937 B IT1167937 B IT 1167937B
Authority
IT
Italy
Prior art keywords
immunopotentiator
skewer
compounds linked
linked
compounds
Prior art date
Application number
IT09465/81A
Other languages
English (en)
Other versions
IT8109465A0 (it
Inventor
Hamao Umezawa
Tomio Takeuchi
Takaaki Aoyagi
Kenji Kawamura
Shunzo Fukatsu
Original Assignee
Microbial Chem Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9169080A external-priority patent/JPS5716842A/ja
Priority claimed from JP9169280A external-priority patent/JPS5718610A/ja
Priority claimed from JP55091691A external-priority patent/JPS6014040B2/ja
Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found
Publication of IT8109465A0 publication Critical patent/IT8109465A0/it
Application granted granted Critical
Publication of IT1167937B publication Critical patent/IT1167937B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT09465/81A 1980-07-07 1981-07-06 Composti collegati alla bestatina come immunopotenziatore IT1167937B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP9169080A JPS5716842A (en) 1980-07-07 1980-07-07 Substance related to bestatin and its preparation
JP9169280A JPS5718610A (en) 1980-07-07 1980-07-07 Immunizator
JP55091691A JPS6014040B2 (ja) 1980-07-07 1980-07-07 ベスタチン新誘導体及びその製造法

Publications (2)

Publication Number Publication Date
IT8109465A0 IT8109465A0 (it) 1981-07-06
IT1167937B true IT1167937B (it) 1987-05-20

Family

ID=27306812

Family Applications (2)

Application Number Title Priority Date Filing Date
IT1981A09465A IT8109465A1 (it) 1980-07-07 1981-07-06 Composti collegati alla bestatina come immunopotenziatore
IT09465/81A IT1167937B (it) 1980-07-07 1981-07-06 Composti collegati alla bestatina come immunopotenziatore

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IT1981A09465A IT8109465A1 (it) 1980-07-07 1981-07-06 Composti collegati alla bestatina come immunopotenziatore

Country Status (6)

Country Link
US (1) US4370318A (it)
CA (1) CA1178610A (it)
DE (2) DE3153030C2 (it)
FR (1) FR2485924A1 (it)
GB (1) GB2083046B (it)
IT (2) IT8109465A1 (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5767516A (en) * 1980-09-24 1982-04-24 Microbial Chem Res Found Novel analgesic agent
JPS58121259A (ja) * 1982-01-09 1983-07-19 Microbial Chem Res Found ベスタチン新規誘導体
WO1983003254A1 (en) * 1982-03-11 1983-09-29 Arthur Babson Stabilization of diazonium salt solutions
WO1986004334A1 (en) * 1985-01-18 1986-07-31 MERCK Patent Gesellschaft mit beschränkter Haftung Immunoregulatory peptides
JPS63233800A (ja) * 1987-03-20 1988-09-29 Toyo Jozo Co Ltd レシチンコレステロ−ルアシルトランスフエラ−ゼの活性測定法
EP0657415B1 (en) * 1993-06-29 1999-09-08 Kaneka Corporation Method of producing 3-amino-2-hydroxy-4-phenyl-butyric acid derivatives and 3-amino-1-nitro-4-phenyl-2-butanol intermediates
WO1998048826A1 (en) * 1997-04-30 1998-11-05 Northwestern University Inhibition of nitric oxide synthase by amino acids and dipeptides
EP3268085A4 (en) 2015-03-13 2018-10-31 The Board of Trustees of The Leland Stanford Junior University Ltb4 inhibition to prevent and treat human lymphedema
CN104984318B (zh) * 2015-06-12 2018-02-06 上海来益生物药物研究开发中心有限责任公司 3‑氨基‑2‑羟基‑4‑苯基‑缬氨酰‑异亮氨酸的新应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1510477A (en) * 1975-07-22 1978-05-10 Microbial Chem Res Found Peptides and to amino acid intermediates thereof
DE2725732C2 (de) * 1977-06-07 1983-01-05 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai, Tokyo Bestatin-Analoga, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
CH650265A5 (de) * 1978-11-25 1985-07-15 Nippon Kayaku Kk Verfahren zur herstellung von substituierten threo-3-amino-2-hydroxybutanoylaminoessigsaeuren.

Also Published As

Publication number Publication date
DE3126606A1 (de) 1982-05-19
US4370318A (en) 1983-01-25
FR2485924A1 (fr) 1982-01-08
IT8109465A0 (it) 1981-07-06
FR2485924B1 (it) 1984-02-17
DE3126606C2 (de) 1986-09-18
DE3153030C2 (de) 1986-01-09
GB2083046B (en) 1984-01-11
GB2083046A (en) 1982-03-17
IT8109465A1 (it) 1983-01-06
CA1178610A (en) 1984-11-27

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970728