IT1146744B - Acidi 2 ammino 3 idrossi fenil metel fenilacetici loro esteri ed ammidi particolarmente utili come antiinfiammatori - Google Patents

Acidi 2 ammino 3 idrossi fenil metel fenilacetici loro esteri ed ammidi particolarmente utili come antiinfiammatori

Info

Publication number
IT1146744B
IT1146744B IT67177/81A IT6717781A IT1146744B IT 1146744 B IT1146744 B IT 1146744B IT 67177/81 A IT67177/81 A IT 67177/81A IT 6717781 A IT6717781 A IT 6717781A IT 1146744 B IT1146744 B IT 1146744B
Authority
IT
Italy
Prior art keywords
phenylacetics
inflammatory
esters
acids
amino
Prior art date
Application number
IT67177/81A
Other languages
English (en)
Italian (it)
Other versions
IT8167177A0 (it
Inventor
William John Welstead Jr
Henry Wayne Moran
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of IT8167177A0 publication Critical patent/IT8167177A0/it
Application granted granted Critical
Publication of IT1146744B publication Critical patent/IT1146744B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT67177/81A 1980-02-19 1981-02-09 Acidi 2 ammino 3 idrossi fenil metel fenilacetici loro esteri ed ammidi particolarmente utili come antiinfiammatori IT1146744B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12254480A 1980-02-19 1980-02-19

Publications (2)

Publication Number Publication Date
IT8167177A0 IT8167177A0 (it) 1981-02-09
IT1146744B true IT1146744B (it) 1986-11-19

Family

ID=22403319

Family Applications (1)

Application Number Title Priority Date Filing Date
IT67177/81A IT1146744B (it) 1980-02-19 1981-02-09 Acidi 2 ammino 3 idrossi fenil metel fenilacetici loro esteri ed ammidi particolarmente utili come antiinfiammatori

Country Status (11)

Country Link
JP (1) JPS56131552A (de)
AU (1) AU538240B2 (de)
BE (1) BE887566A (de)
CA (1) CA1156655A (de)
CH (1) CH648283A5 (de)
DE (1) DE3105285A1 (de)
FR (1) FR2476071A1 (de)
GB (1) GB2071086B (de)
IL (1) IL61945A (de)
IT (1) IT1146744B (de)
NL (1) NL8100808A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues
IL64724A0 (en) * 1981-02-17 1982-03-31 Robins Co Inc A H 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
AR030346A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
WO2002078681A2 (en) 2001-04-02 2002-10-10 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac
TWI358290B (en) 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
CA2755314A1 (en) * 2009-03-12 2010-09-16 Medichem, S.A. New crystals of a benzoylbenzeneacetamide derivative
EP2389354A1 (de) * 2009-04-06 2011-11-30 Medichem, S.A. 2-{2-amino-3-[hydroxy(phenyl)methyl]phenyl}-acetamid
CN106631881B (zh) * 2016-09-08 2018-09-21 南京工业大学 2-（3-苄基-2-（二甲基氨基）苯基）乙酰胺及合成方法和用途
CN112794809B (zh) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 一种高纯度奈帕芬胺中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
FR2366015A1 (fr) * 1975-11-05 1978-04-28 Robins Co Inc A H Nouveaux acides amino-2 benzoyl-3 (5 et 6) phenylacetiques et leurs esters et sels de metaux alcalins, utiles notamment comme anti-inflammatoires, et leur procede de preparation
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues

Also Published As

Publication number Publication date
IL61945A0 (en) 1981-02-27
FR2476071B1 (de) 1984-05-11
GB2071086B (en) 1984-02-08
IT8167177A0 (it) 1981-02-09
JPH0153266B2 (de) 1989-11-13
JPS56131552A (en) 1981-10-15
BE887566A (fr) 1981-06-15
AU6733081A (en) 1981-08-27
AU538240B2 (en) 1984-08-02
NL8100808A (nl) 1981-09-16
DE3105285A1 (de) 1982-01-21
GB2071086A (en) 1981-09-16
CA1156655A (en) 1983-11-08
IL61945A (en) 1984-09-30
FR2476071A1 (fr) 1981-08-21
CH648283A5 (fr) 1985-03-15

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