IS7630A - Skiptitengdar heterósýklískar afleiður, og aðferð, gagnlegar sem virk efni gegn sykursýki og offitu - Google Patents
Skiptitengdar heterósýklískar afleiður, og aðferð, gagnlegar sem virk efni gegn sykursýki og offituInfo
- Publication number
- IS7630A IS7630A IS7630A IS7630A IS7630A IS 7630 A IS7630 A IS 7630A IS 7630 A IS7630 A IS 7630A IS 7630 A IS7630 A IS 7630A IS 7630 A IS7630 A IS 7630A
- Authority
- IS
- Iceland
- Prior art keywords
- exchangeable
- diabetic
- obesity agent
- method useful
- heterocyclic derivatives
- Prior art date
Links
- 230000003178 anti-diabetic effect Effects 0.000 title 1
- 239000000883 anti-obesity agent Substances 0.000 title 1
- 239000003472 antidiabetic agent Substances 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39450802P | 2002-07-09 | 2002-07-09 | |
PCT/US2003/022149 WO2004004665A2 (en) | 2002-07-09 | 2003-07-02 | Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method |
Publications (1)
Publication Number | Publication Date |
---|---|
IS7630A true IS7630A (is) | 2005-01-05 |
Family
ID=30115727
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IS7630A IS7630A (is) | 2002-07-09 | 2005-01-05 | Skiptitengdar heterósýklískar afleiður, og aðferð, gagnlegar sem virk efni gegn sykursýki og offitu |
Country Status (9)
Country | Link |
---|---|
US (2) | US7279485B2 (is) |
EP (1) | EP1656368A4 (is) |
JP (1) | JP4579681B2 (is) |
AU (1) | AU2003259131A1 (is) |
IS (1) | IS7630A (is) |
NO (1) | NO329938B1 (is) |
PL (1) | PL374860A1 (is) |
TW (1) | TW200422298A (is) |
WO (1) | WO2004004665A2 (is) |
Families Citing this family (34)
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JP2005519876A (ja) * | 2001-11-27 | 2005-07-07 | メルク エンド カムパニー インコーポレーテッド | 2−アミノキノリン化合物 |
WO2003045920A1 (en) * | 2001-11-27 | 2003-06-05 | Merck & Co., Inc. | 4-aminoquinoline compounds |
BR0315713A (pt) * | 2002-11-15 | 2005-09-13 | Cadila Healthcare Ltd | Composto, processo para a preparação do composto, composição farmacêutica, métodos para reduzir a glicose, para a prevenção ou para o tratamento de doenças e uso do composto |
WO2004069798A1 (ja) * | 2003-02-10 | 2004-08-19 | Banyu Pharmaceutical Co.,Ltd. | ピペリジン誘導体を有効成分とするメラニン凝集ホルモン受容体拮抗剤 |
DE10308355A1 (de) | 2003-02-27 | 2004-12-23 | Aventis Pharma Deutschland Gmbh | Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel |
CA2581596A1 (en) * | 2004-09-29 | 2006-04-13 | Schering Corporation | Combinations of substituted azetidonones and cb1 antagonists |
GB0505969D0 (en) | 2005-03-23 | 2005-04-27 | Novartis Ag | Organic compounds |
JP5140577B2 (ja) | 2005-03-31 | 2013-02-06 | タケダ カリフォルニア インコーポレイテッド | ヒドロキシステロイドデヒドロゲナーゼ阻害剤 |
PE20070097A1 (es) * | 2005-06-28 | 2007-03-08 | Merck Sharp & Dohme | Agonistas del receptor de niacina y composiciones que contienen tales compuestos |
US7879997B2 (en) * | 2005-08-12 | 2011-02-01 | Schering Corporation | Compounds for the treatment of inflammatory disorders |
MY147393A (en) | 2005-09-14 | 2012-11-30 | Takeda Pharmaceutical | Administration of dipeptidyl peptidase inhibitors |
CN102675221A (zh) | 2005-09-16 | 2012-09-19 | 武田药品工业株式会社 | 用于制备嘧啶二酮衍生物的方法中的中间体 |
ES2430139T3 (es) | 2005-12-30 | 2013-11-19 | Novartis Ag | Compuestos de piperidina 3,5-sustituido como inhibidores de renina |
WO2007112347A1 (en) | 2006-03-28 | 2007-10-04 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US8324383B2 (en) | 2006-09-13 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile |
TW200838536A (en) | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
US8093236B2 (en) | 2007-03-13 | 2012-01-10 | Takeda Pharmaceuticals Company Limited | Weekly administration of dipeptidyl peptidase inhibitors |
CN101687847B (zh) | 2007-06-25 | 2013-11-06 | 诺华股份有限公司 | 用作肾素抑制剂的n5-(2-乙氧基乙基)-n3-(2-吡啶基)-3,5-哌啶二甲酰胺衍生物 |
SG172217A1 (en) * | 2008-12-16 | 2011-07-28 | Hoffmann La Roche | Process for the preparation of pyrollidine-3-carboxylic acids |
AR075177A1 (es) * | 2009-01-28 | 2011-03-16 | Sanofi Aventis | Derivados de tiadiazoles y oxadiazoles, metodo de preparacion, intermediarios de sintesis, composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento de trastornos metabolicos, tales como obesidad y diabetes, entre otros. |
FR2941457A1 (fr) * | 2009-01-28 | 2010-07-30 | Sanofi Aventis | Derives de thiadiazoles et d'oxadiazoles leur preparation et leur application en therapeutique |
BR112012007979A2 (pt) * | 2009-10-06 | 2016-03-29 | Bristol Myers Squibb Co | moduladores de gpr40 de pirrolidina |
CA2801074A1 (en) | 2010-06-04 | 2011-12-08 | Albany Molecular Research, Inc. | Glycine transporter-1 inhibitors, methods of making them, and uses thereof |
AU2013202982C1 (en) | 2012-01-06 | 2017-01-05 | Novartis Ag | Heterocyclic compounds and methods for their use |
PL2807153T3 (pl) * | 2012-01-25 | 2020-09-07 | Novartis Ag | Związki heterocykliczne i sposoby ich zastosowania |
CN104812748B (zh) | 2012-11-16 | 2017-10-24 | 百时美施贵宝公司 | 二氢吡唑gpr40调节剂 |
US9701860B2 (en) * | 2013-02-19 | 2017-07-11 | Sun Chemical Corporation | Printable radiation curable barrier coatings |
US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
JP2017119628A (ja) * | 2014-05-09 | 2017-07-06 | 日産化学工業株式会社 | 置換アゾール化合物及び糖尿病治療薬 |
CN107677753B (zh) * | 2017-11-24 | 2021-03-16 | 中山奕安泰医药科技有限公司 | 一种依替米贝中间体的检测方法 |
EP3886854A4 (en) | 2018-11-30 | 2022-07-06 | Nuvation Bio Inc. | PYRROLE AND PYRAZOLE COMPOUNDS AND METHODS OF USE THERE |
CN112876427B (zh) * | 2021-01-18 | 2022-04-22 | 万华化学集团股份有限公司 | 一种安赛蜜的制备方法 |
CN112679407B (zh) * | 2021-03-17 | 2021-06-04 | 南京桦冠生物技术有限公司 | 一种手性5-取代脯氨酸类化合物的制备方法 |
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JPH05213884A (ja) | 1991-06-14 | 1993-08-24 | Upjohn Co:The | 新規な4−アミノキノリン類およびこれを有効成分とする高血圧・鬱血性心不全の予防・治療剤 |
GB9113628D0 (en) | 1991-06-25 | 1991-08-14 | Ici Plc | Heterocyclic derivatives |
US5631365A (en) * | 1993-09-21 | 1997-05-20 | Schering Corporation | Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents |
US5686442A (en) | 1993-12-28 | 1997-11-11 | Meiji Seika Kabushiki Kaisha | Tricyclic benzazepine and benzothiazepine derivatives |
JPH08325263A (ja) | 1995-05-31 | 1996-12-10 | Sumitomo Metal Ind Ltd | 新規2−アミノ−3−フェニルプロピオン酸誘導体 |
US6143718A (en) * | 1995-06-07 | 2000-11-07 | Amylin Pharmaceuticals, Inc. | Treatment of Type II diabetes mellutis with amylin agonists |
KR100286494B1 (ko) | 1995-06-15 | 2001-04-16 | 이치로 키타사토 | 삼환성벤즈아제핀화합물 |
WO1997027847A1 (en) | 1996-02-02 | 1997-08-07 | Merck & Co., Inc. | Method of treating diabetes and related disease states |
AU1856997A (en) | 1996-02-02 | 1997-08-22 | Merck & Co., Inc. | Method for raising hdl cholesterol levels |
ATE236137T1 (de) | 1996-02-02 | 2003-04-15 | Merck & Co Inc | Heterocyclische verbindungen als antidiabetische mittel und für die behandlung von fettleibigkeit |
EP0904079B1 (en) | 1996-02-02 | 2004-03-24 | Merck & Co., Inc. | Antidiabetic agents |
GB9604242D0 (en) | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
IL121202A (en) | 1996-07-01 | 2001-08-26 | Lilly Co Eli | Hypoglycemic and hypolipidemic compounds, process for their preparation, pharmaceutial compositions comprising same, and uses thereof |
ATE277907T1 (de) | 1996-07-01 | 2004-10-15 | Lilly Co Eli | Blutzuckersenkende und lipidsenkende verbindungen |
JP2001511767A (ja) | 1996-12-23 | 2001-08-14 | メルク エンド カンパニー インコーポレーテッド | 糖尿病薬 |
WO1999007357A1 (fr) | 1997-08-08 | 1999-02-18 | Ono Pharmaceutical Co., Ltd. | REGULATEURS DE TYPE η DE RECEPTEUR ACTIVE D'AGENT DE PROLIFERATION DE PEROXYSOME |
AU8750298A (en) | 1997-08-28 | 1999-03-22 | Ono Pharmaceutical Co. Ltd. | Peroxisome proliferator-activated receptor controllers |
AU9002798A (en) | 1997-09-19 | 1999-04-12 | Ono Pharmaceutical Co. Ltd. | Fused or nonfused benzene compounds |
US6372735B1 (en) | 1997-09-29 | 2002-04-16 | Meiji Seika Kaisha, Ltd. | Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic |
CA2306825A1 (en) | 1997-10-17 | 1999-04-29 | Avantis Pharmaceuticals Products Inc. | Therapeutic uses of quinoline derivatives |
CN1280574A (zh) | 1997-10-27 | 2001-01-17 | 雷迪研究基金会 | 新的杂环化合物及其在医药中的应用、它们的制备方法和含有它们的药物组合物 |
EP1067109B1 (en) * | 1998-03-10 | 2009-12-09 | Ono Pharmaceutical Co., Ltd. | Carboxylic acid derivatives and drugs containing the same as the active ingredient |
CN1208326C (zh) | 1998-04-23 | 2005-06-29 | 雷迪实验室有限公司 | 杂环化合物及其在医药方面的应用、其制备方法及含有它们的药物组合物 |
OA11577A (en) * | 1998-06-30 | 2004-07-26 | Pfizer Prod Inc | Non-peptidyl inhibitors of VLA-4 dependent cell vinding useful in treating inflammatory, autoimmune,and respiratory diseases. |
GB9817118D0 (en) | 1998-08-07 | 1998-10-07 | Glaxo Group Ltd | Pharmaceutical compounds |
JP4598278B2 (ja) | 1999-04-28 | 2010-12-15 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Ppar受容体リガンドとしてのジアリール酸誘導体 |
SK15522001A3 (sk) | 1999-04-28 | 2002-06-04 | Aventis Pharma Deutschland Gmbh | Deriváty kyselín s tromi arylovými zvyškami ako ligandy receptorov PPAR a farmaceutické kompozície, ktoré ich obsahujú |
US6414002B1 (en) * | 1999-09-22 | 2002-07-02 | Bristol-Myers Squibb Company | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method |
TWI260321B (en) * | 1999-09-22 | 2006-08-21 | Bristol Myers Squibb Co | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method |
ES2225252T3 (es) * | 1999-11-10 | 2005-03-16 | Takeda Chemical Industries, Ltd. | Compuestos n-heterociclicos de 5 miembros con actividad hipoglucemica e hipolipidemica. |
US7105556B2 (en) * | 2001-05-30 | 2006-09-12 | Bristol-Myers Squibb Company | Conformationally constrained analogs useful as antidiabetic and antiobesity agents and method |
US6967212B2 (en) * | 2001-05-30 | 2005-11-22 | Bristol-Myers Squibb Company | Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method |
-
2003
- 2003-07-02 PL PL03374860A patent/PL374860A1/xx not_active Application Discontinuation
- 2003-07-02 WO PCT/US2003/022149 patent/WO2004004665A2/en active Application Filing
- 2003-07-02 EP EP03763485A patent/EP1656368A4/en not_active Withdrawn
- 2003-07-02 JP JP2004520148A patent/JP4579681B2/ja not_active Expired - Fee Related
- 2003-07-02 AU AU2003259131A patent/AU2003259131A1/en not_active Abandoned
- 2003-07-07 TW TW092118514A patent/TW200422298A/zh unknown
- 2003-07-08 US US10/616,365 patent/US7279485B2/en active Active
-
2005
- 2005-01-05 IS IS7630A patent/IS7630A/is unknown
- 2005-01-06 NO NO20050077A patent/NO329938B1/no not_active IP Right Cessation
-
2007
- 2007-07-18 US US11/779,319 patent/US7951793B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
PL374860A1 (en) | 2005-11-14 |
WO2004004665A2 (en) | 2004-01-15 |
US20040063700A1 (en) | 2004-04-01 |
NO20050077L (no) | 2005-02-03 |
US20070287713A1 (en) | 2007-12-13 |
EP1656368A4 (en) | 2009-08-26 |
NO329938B1 (no) | 2011-01-24 |
US7951793B2 (en) | 2011-05-31 |
AU2003259131A8 (en) | 2004-01-23 |
TW200422298A (en) | 2004-11-01 |
JP4579681B2 (ja) | 2010-11-10 |
WO2004004665A3 (en) | 2004-03-25 |
US7279485B2 (en) | 2007-10-09 |
EP1656368A2 (en) | 2006-05-17 |
AU2003259131A1 (en) | 2004-01-23 |
JP2005536494A (ja) | 2005-12-02 |
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