PL2807153T3 - Związki heterocykliczne i sposoby ich zastosowania - Google Patents
Związki heterocykliczne i sposoby ich zastosowaniaInfo
- Publication number
- PL2807153T3 PL2807153T3 PL13741446T PL13741446T PL2807153T3 PL 2807153 T3 PL2807153 T3 PL 2807153T3 PL 13741446 T PL13741446 T PL 13741446T PL 13741446 T PL13741446 T PL 13741446T PL 2807153 T3 PL2807153 T3 PL 2807153T3
- Authority
- PL
- Poland
- Prior art keywords
- methods
- heterocyclic compounds
- heterocyclic
- compounds
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2012900286A AU2012900286A0 (en) | 2012-01-25 | "Methods of treatment or prophylaxis" | |
| PCT/AU2013/000061 WO2013110134A1 (en) | 2012-01-25 | 2013-01-25 | Heterocyclic compounds and methods for their use |
| EP13741446.2A EP2807153B1 (en) | 2012-01-25 | 2013-01-25 | Heterocyclic compounds and methods for their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2807153T3 true PL2807153T3 (pl) | 2020-09-07 |
Family
ID=48872832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13741446T PL2807153T3 (pl) | 2012-01-25 | 2013-01-25 | Związki heterocykliczne i sposoby ich zastosowania |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20150011565A1 (pl) |
| EP (1) | EP2807153B1 (pl) |
| JP (2) | JP6258867B2 (pl) |
| CN (1) | CN104470903B (pl) |
| AU (1) | AU2013202973C9 (pl) |
| CA (1) | CA2861231C (pl) |
| ES (1) | ES2798289T3 (pl) |
| NZ (1) | NZ627560A (pl) |
| PL (1) | PL2807153T3 (pl) |
| PT (1) | PT2807153T (pl) |
| WO (1) | WO2013110134A1 (pl) |
| ZA (1) | ZA201405255B (pl) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2621708C2 (ru) | 2011-06-22 | 2017-06-07 | ПУРДЬЮ ФАРМА Эл. Пи. | Антагонисты trpv1, включающие дигидроксигруппу в качестве заместителя, и их применение |
| AU2013202982C1 (en) | 2012-01-06 | 2017-01-05 | Novartis Ag | Heterocyclic compounds and methods for their use |
| CN104470903B (zh) * | 2012-01-25 | 2017-02-22 | 诺华股份有限公司 | 杂环化合物和它们的使用方法 |
| NZ630908A (en) | 2013-07-08 | 2017-08-25 | Novartis Ag | Heterocyclic compounds and methods of their use |
| TR201807959T4 (tr) | 2013-07-22 | 2018-06-21 | Idorsia Pharmaceuticals Ltd | 1-(Piperazın-1-il)-2- ([1,2,4] triazol-1-il)-etanon türevleri. |
| WO2015063709A1 (en) * | 2013-10-31 | 2015-05-07 | Ranbaxy Laboratories Limited | Process for the preparation of 1-(3-methyl-1-phenyl-1h-pyrazol-5-yl)piperazine |
| EP3245198B1 (en) | 2015-01-13 | 2020-03-11 | Novartis AG | Pyrrolidine derivatives as angiotensin ii type 2 antagonists |
| AR103399A1 (es) | 2015-01-15 | 2017-05-10 | Actelion Pharmaceuticals Ltd | Derivados de (r)-2-metil-piperazina como moduladores del receptor cxcr3 |
| TN2017000278A1 (en) | 2015-01-15 | 2019-01-16 | Idorsia Pharmaceuticals Ltd | Hydroxyalkyl-piperazine derivatives as cxcr3 receptor modulators |
| ES2898635T3 (es) | 2015-03-12 | 2022-03-08 | Novartis Ag | Compuestos heterocíclicos y métodos para su uso |
| CN105503787A (zh) * | 2015-12-31 | 2016-04-20 | 阜阳欣奕华材料科技有限公司 | 一种索非布韦中间体的纯化方法 |
| WO2019040105A2 (en) * | 2017-08-21 | 2019-02-28 | Acadia Pharmaceuticals Inc. | COMPOUNDS, SALTS THEREOF AND METHODS FOR THE TREATMENT OF DISEASES |
| TWI810229B (zh) | 2017-12-15 | 2023-08-01 | 瑞士商英夕亞生物科技公司 | 側氧哌嗪衍生物 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4400511A (en) * | 1982-05-07 | 1983-08-23 | American Home Products Corporation | 2-Substituted octahydropyrrolo(1,2-A)-pyrazine-3-carboxylic acids |
| CA2017020A1 (en) * | 1989-05-18 | 1990-11-18 | Alan Naylor | Chemical compounds |
| WO1992020661A1 (en) * | 1991-05-22 | 1992-11-26 | Merck & Co., Inc. | N, n-diacylpiperazines |
| US5344830A (en) * | 1992-12-10 | 1994-09-06 | Merck & Co., Inc. | N,N-diacylpiperazine tachykinin antagonists |
| US5348955A (en) * | 1993-06-22 | 1994-09-20 | Merck & Co., Inc. | N,N-diacylpiperazines |
| US5464788A (en) * | 1994-03-24 | 1995-11-07 | Merck & Co., Inc. | Tocolytic oxytocin receptor antagonists |
| EP0926138A4 (en) * | 1996-08-23 | 2006-04-12 | Kowa Co | DIAMIDE COMPOUNDS AND MEDICAMENTS CONTAINING SAME |
| DE69825589T2 (de) * | 1997-06-17 | 2005-09-08 | Schering Corp. | Benzpyrido cycloheptan derivate mit farnesyl protein transferase inhibierender wirkung |
| US5968938A (en) * | 1997-06-18 | 1999-10-19 | Merck & Co., Inc. | Piperazine oxytocin receptor antagonists |
| US6951862B2 (en) * | 1998-06-30 | 2005-10-04 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
| US20060084660A1 (en) * | 1998-06-30 | 2006-04-20 | Neuromed Technologies Inc. | Calcium channel blockers comprising two benzhydril moieties |
| US20050256130A1 (en) * | 2002-06-12 | 2005-11-17 | Chemocentryx, Inc. | Substituted piperazines |
| US7589199B2 (en) * | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
| EP1656368A4 (en) * | 2002-07-09 | 2009-08-26 | Bristol Myers Squibb Co | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS ANTIDIABETIC AGENTS AND ANTIABESITY AND THEIR MANUFACTURING PROCESS |
| DE10309005A1 (de) * | 2003-03-01 | 2004-09-09 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen, die Dipetidyl Peptidase (DPPIV) und Neurale Endopeptidase (NEP) inhibieren |
| KR20070044803A (ko) * | 2004-04-09 | 2007-04-30 | 뉴로메드 파머큐티칼즈 리미티드 | 칼슘 채널 차단제로서 디아릴아민 유도체 |
| PT1830869E (pt) | 2004-12-24 | 2013-08-22 | Spinifex Pharm Pty Ltd | Método de tratamento ou profilaxia |
| WO2006086609A2 (en) * | 2005-02-10 | 2006-08-17 | Axys Pharmaceuticals, Inc. | Inhibitors of tryptase |
| US20070049578A1 (en) * | 2005-08-24 | 2007-03-01 | Astrazeneca Ab | Cinnamamide compounds as metabotropic glutamate receptor antagonists |
| WO2007063934A1 (ja) * | 2005-12-02 | 2007-06-07 | Mitsubishi Tanabe Pharma Corporation | 脂環式複素環化合物 |
| US8551950B2 (en) | 2006-03-20 | 2013-10-08 | Spinifex Pharmaceuticals Pty Ltd | Method of treatment or prophylaxis of inflammatory pain |
| US8362021B2 (en) * | 2006-05-11 | 2013-01-29 | Zalicus Pharmaceuticals Ltd. | Method for increasing the bioavailability of benzhydryl piperazine containing compounds |
| JP2008031064A (ja) * | 2006-07-27 | 2008-02-14 | Astellas Pharma Inc | ジアシルピペラジン誘導体 |
| JP2009007341A (ja) * | 2007-06-01 | 2009-01-15 | Mitsubishi Tanabe Pharma Corp | 医薬組成物 |
| JP5433690B2 (ja) | 2008-06-25 | 2014-03-05 | ブリストル−マイヤーズ スクイブ カンパニー | 抗−ｈｉｖ薬としてのジケト縮合アゾロピペリジンおよびアゾロピペラジン |
| JP6232184B2 (ja) | 2010-01-19 | 2017-11-15 | ノバルティス アーゲー | 神経伝導速度改善のための方法および組成物 |
| AU2013202982C1 (en) | 2012-01-06 | 2017-01-05 | Novartis Ag | Heterocyclic compounds and methods for their use |
| CA2861233C (en) | 2012-01-25 | 2021-05-04 | Spinifex Pharmaceuticals Pty Ltd | Heterocyclic compounds and methods for their use |
| CN104470903B (zh) * | 2012-01-25 | 2017-02-22 | 诺华股份有限公司 | 杂环化合物和它们的使用方法 |
-
2013
- 2013-01-25 CN CN201380016259.9A patent/CN104470903B/zh active Active
- 2013-01-25 WO PCT/AU2013/000061 patent/WO2013110134A1/en not_active Ceased
- 2013-01-25 JP JP2014553581A patent/JP6258867B2/ja active Active
- 2013-01-25 CA CA2861231A patent/CA2861231C/en active Active
- 2013-01-25 AU AU2013202973A patent/AU2013202973C9/en active Active
- 2013-01-25 US US14/373,355 patent/US20150011565A1/en not_active Abandoned
- 2013-01-25 ES ES13741446T patent/ES2798289T3/es active Active
- 2013-01-25 PL PL13741446T patent/PL2807153T3/pl unknown
- 2013-01-25 PT PT137414462T patent/PT2807153T/pt unknown
- 2013-01-25 NZ NZ627560A patent/NZ627560A/en unknown
- 2013-01-25 EP EP13741446.2A patent/EP2807153B1/en active Active
-
2014
- 2014-07-17 ZA ZA2014/05255A patent/ZA201405255B/en unknown
-
2016
- 2016-05-09 US US15/149,641 patent/US9708275B2/en active Active
-
2017
- 2017-10-25 JP JP2017205744A patent/JP2018076297A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU2013202973B9 (en) | 2016-11-24 |
| NZ627560A (en) | 2016-08-26 |
| PT2807153T (pt) | 2020-06-18 |
| ZA201405255B (en) | 2019-04-24 |
| JP2018076297A (ja) | 2018-05-17 |
| US20160257656A1 (en) | 2016-09-08 |
| EP2807153B1 (en) | 2020-03-25 |
| WO2013110134A1 (en) | 2013-08-01 |
| ES2798289T3 (es) | 2020-12-10 |
| CA2861231A1 (en) | 2013-08-01 |
| CA2861231C (en) | 2021-04-13 |
| HK1201533A1 (en) | 2015-09-04 |
| AU2013202973C9 (en) | 2016-12-22 |
| AU2013202973C1 (en) | 2016-11-24 |
| EP2807153A1 (en) | 2014-12-03 |
| EP2807153A4 (en) | 2015-06-10 |
| CN104470903A (zh) | 2015-03-25 |
| CN104470903B (zh) | 2017-02-22 |
| JP2015504900A (ja) | 2015-02-16 |
| US9708275B2 (en) | 2017-07-18 |
| JP6258867B2 (ja) | 2018-01-10 |
| US20150011565A1 (en) | 2015-01-08 |
| AU2013202973B2 (en) | 2016-06-02 |
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