IS4181A - Fúkósýleruð glýkósíð sem hindra viðloðun baktería - Google Patents
Fúkósýleruð glýkósíð sem hindra viðloðun bakteríaInfo
- Publication number
- IS4181A IS4181A IS4181A IS4181A IS4181A IS 4181 A IS4181 A IS 4181A IS 4181 A IS4181 A IS 4181A IS 4181 A IS4181 A IS 4181A IS 4181 A IS4181 A IS 4181A
- Authority
- IS
- Iceland
- Prior art keywords
- fucosylated
- glycosides
- bacteria
- inhibit
- adhesion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK93761A DK76193D0 (da) | 1993-06-25 | 1993-06-25 | Kulhydratderivater |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS4181A true IS4181A (is) | 1994-12-26 |
Family
ID=8097261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS4181A IS4181A (is) | 1993-06-25 | 1994-06-22 | Fúkósýleruð glýkósíð sem hindra viðloðun baktería |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0706528A1 (fr) |
| JP (1) | JPH08512026A (fr) |
| AU (1) | AU7089194A (fr) |
| CA (1) | CA2164961A1 (fr) |
| DK (1) | DK76193D0 (fr) |
| IL (1) | IL110074A0 (fr) |
| IS (1) | IS4181A (fr) |
| LT (1) | LT3446B (fr) |
| WO (1) | WO1995000527A1 (fr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204431B1 (en) | 1994-03-09 | 2001-03-20 | Abbott Laboratories | Transgenic non-human mammals expressing heterologous glycosyltransferase DNA sequences produce oligosaccharides and glycoproteins in their milk |
| JPH1160590A (ja) * | 1997-08-22 | 1999-03-02 | Yakult Honsha Co Ltd | オリゴフコース誘導体又はオリゴラムノース誘導体及びその製造法 |
| SE9901007D0 (sv) * | 1999-03-19 | 1999-03-19 | Thomas Boren | Use of fucosylated sialylated N-acetyl lactosamin carbohydrate structures for inhibition of bacterial adherence |
| AU2006280101B2 (en) * | 2005-08-09 | 2012-06-28 | Glycomimetics, Inc. | Glycomimetic inhibitors of the PA-IL lectin, PA-IIL lectin or both the lectins from Pseudomonas |
| WO2012037034A1 (fr) | 2010-09-14 | 2012-03-22 | Glycomimetics, Inc. | Antagonistes de l'e-sélectine |
| JP2015500887A (ja) | 2011-12-22 | 2015-01-08 | グリコミメティクス， インコーポレイテッド | Ｅ−セレクチンアンタゴニスト化合物、組成物および使用方法 |
| EP2692740A1 (fr) * | 2012-07-30 | 2014-02-05 | Le Centre National De La Recherche Scientifique | Compositions de glycane, leurs procédés de préparation et leurs utilisations en tant que médicament |
| AU2013355238B2 (en) | 2012-12-07 | 2017-12-14 | Glycomimetics, Inc. | Compounds, compositions and methods using E-selectin antagonists for mobilization of hematopoietic cells |
| CN105101972A (zh) * | 2013-01-31 | 2015-11-25 | 先锋国际良种公司 | 用于改善植物生长和产量的合成型脂质几丁寡糖 |
| EP3013365B1 (fr) * | 2013-06-26 | 2019-06-05 | Academia Sinica | Antigènes rm2 et leur utilisation |
| SI3227310T1 (sl) | 2014-12-03 | 2019-11-29 | Glycomimetics Inc | Heterobifunkcionalni inhibitorji e-selektinov in receptorjev kemokina CXCR4 |
| CA3009836A1 (fr) | 2016-01-22 | 2017-07-27 | Glycomimetics, Inc. | Inhibiteurs glycomimetiques des lectines pa-il et pa-iil |
| US11291678B2 (en) | 2016-03-02 | 2022-04-05 | Glycomimetics, Inc | Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin |
| WO2018031445A1 (fr) | 2016-08-08 | 2018-02-15 | Glycomimetics, Inc. | Combinaison d'inhibiteurs des points de contrôle des lymphocytes t avec des inhibiteurs de e-sélectine ou de cxcr4, ou avec des inhibiteurs hétérobifonctionnels de e-sélectine et de cxcr4 |
| JP7069136B2 (ja) | 2016-10-07 | 2022-05-17 | グリコミメティクス， インコーポレイテッド | 極めて強力な多量体ｅ－セレクチンアンタゴニスト |
| EP3596096A1 (fr) | 2017-03-15 | 2020-01-22 | GlycoMimetics, Inc. | Dérivés de galactopyranosyle-cyclohexyle utilisés en tant qu'antagonistes d'e-sélectine |
| JP7275131B2 (ja) | 2017-11-30 | 2023-05-17 | グリコミメティクス， インコーポレイテッド | 骨髄浸潤リンパ球を動員する方法、およびその使用 |
| CN111566117A (zh) | 2017-12-29 | 2020-08-21 | 糖模拟物有限公司 | E-选择蛋白和半乳凝素-3的异双功能抑制剂 |
| JP7455064B2 (ja) | 2018-03-05 | 2024-03-25 | グリコミメティクス， インコーポレイテッド | 急性骨髄性白血病および関連状態を処置する方法 |
| KR20210057053A (ko) | 2018-08-23 | 2021-05-20 | 씨젠 인크. | 항-tigit 항체 |
| AU2019416330A1 (en) | 2018-12-27 | 2021-07-01 | Glycomimetics, Inc. | Galectin-3 inhibiting c-glycosides |
| WO2020139962A1 (fr) | 2018-12-27 | 2020-07-02 | Glycomimetics, Inc. | Inhibiteurs hétérobifonctionnels d'e-sélectine et de galectine-3 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1603609A (en) * | 1977-04-14 | 1981-11-25 | Chembiomed Ltd | O-protected 2-azido-2-deoxy-glycosyl nitrates |
| FR2509313A1 (fr) * | 1981-07-08 | 1983-01-14 | Choay Sa | Derives de 3-fucosyl-n-acetyl lactosamine, leur preparation et leurs applications biologiques |
| DE3220427A1 (de) * | 1982-05-29 | 1983-12-01 | Behringwerke Ag, 3550 Marburg | Ss-d-galactosederivate, verfahren zu ihrer herstellung und ihre verwendung |
| DK17685D0 (da) * | 1985-01-14 | 1985-01-14 | Hans Goeran Magnusson | Glycosidderivater |
| AU609999B2 (en) * | 1988-06-21 | 1991-05-09 | Marion Laboratories, Inc. | Bismuth (phosph/sulf)ated saccharides |
-
1993
- 1993-06-25 DK DK93761A patent/DK76193D0/da not_active Application Discontinuation
-
1994
- 1994-06-17 EP EP94919945A patent/EP0706528A1/fr not_active Withdrawn
- 1994-06-17 AU AU70891/94A patent/AU7089194A/en not_active Abandoned
- 1994-06-17 WO PCT/SE1994/000604 patent/WO1995000527A1/fr not_active Application Discontinuation
- 1994-06-17 CA CA002164961A patent/CA2164961A1/fr not_active Abandoned
- 1994-06-17 JP JP7502720A patent/JPH08512026A/ja active Pending
- 1994-06-21 IL IL11007494A patent/IL110074A0/xx unknown
- 1994-06-22 IS IS4181A patent/IS4181A/is unknown
- 1994-06-27 LT LTIP1978A patent/LT3446B/lt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU7089194A (en) | 1995-01-17 |
| WO1995000527A1 (fr) | 1995-01-05 |
| LTIP1978A (en) | 1995-01-31 |
| JPH08512026A (ja) | 1996-12-17 |
| CA2164961A1 (fr) | 1995-01-05 |
| DK76193D0 (da) | 1993-06-25 |
| IL110074A0 (en) | 1994-10-07 |
| EP0706528A1 (fr) | 1996-04-17 |
| LT3446B (en) | 1995-10-25 |
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