LTIP1978A - Fucolsylated glycosides as inhibitor of bacterial adherence - Google Patents
Fucolsylated glycosides as inhibitor of bacterial adherenceInfo
- Publication number
- LTIP1978A LTIP1978A LTIP1978A LTIP1978A LTIP1978A LT IP1978 A LTIP1978 A LT IP1978A LT IP1978 A LTIP1978 A LT IP1978A LT IP1978 A LTIP1978 A LT IP1978A LT IP1978 A LTIP1978 A LT IP1978A
- Authority
- LT
- Lithuania
- Prior art keywords
- fucolsylated
- glycosides
- inhibitor
- bacterial adherence
- adherence
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK93761A DK76193D0 (en) | 1993-06-25 | 1993-06-25 | CARBOHYDRATE DERIVATIVES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LTIP1978A true LTIP1978A (en) | 1995-01-31 |
| LT3446B LT3446B (en) | 1995-10-25 |
Family
ID=8097261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTIP1978A LT3446B (en) | 1993-06-25 | 1994-06-27 | Fucolsylated glycosides as inhibitor of bacterial adherence |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0706528A1 (en) |
| JP (1) | JPH08512026A (en) |
| AU (1) | AU7089194A (en) |
| CA (1) | CA2164961A1 (en) |
| DK (1) | DK76193D0 (en) |
| IL (1) | IL110074A0 (en) |
| IS (1) | IS4181A (en) |
| LT (1) | LT3446B (en) |
| WO (1) | WO1995000527A1 (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204431B1 (en) | 1994-03-09 | 2001-03-20 | Abbott Laboratories | Transgenic non-human mammals expressing heterologous glycosyltransferase DNA sequences produce oligosaccharides and glycoproteins in their milk |
| JPH1160590A (en) * | 1997-08-22 | 1999-03-02 | Yakult Honsha Co Ltd | Oligofucose derivative or oligorhamnose derivative and method for producing the same |
| SE9901007D0 (en) * | 1999-03-19 | 1999-03-19 | Thomas Boren | Use of fucosylated sialylated N-acetyl lactosamine carbohydrate structures for inhibition of bacterial adherence |
| US7517980B2 (en) * | 2005-08-09 | 2009-04-14 | Glycomimetics, Inc. | Glycomimetric inhibitors of the PA-IL lectin, PA-IIL lectin or both the lectins from Pseudomonas |
| US8921328B2 (en) | 2010-09-14 | 2014-12-30 | Glycomimetics, Inc. | E-selectin antagonists |
| EP2794626B3 (en) | 2011-12-22 | 2020-08-05 | GlycoMimetics, Inc. | E-selectin antagonist compounds |
| EP2692740A1 (en) * | 2012-07-30 | 2014-02-05 | Le Centre National De La Recherche Scientifique | Glycan compositions, processes for preparing the same and their uses as a drug |
| SI2928476T1 (en) | 2012-12-07 | 2018-06-29 | Glycomimetics, Inc. | Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells |
| EP2950801A1 (en) * | 2013-01-31 | 2015-12-09 | Pioneer Hi-Bred International, Inc. | Synthetic lipochitooligosaccharides for improvement of plant growth and yield |
| WO2014210397A1 (en) * | 2013-06-26 | 2014-12-31 | Academia Sinica | Rm2 antigens and use thereof |
| HUE045542T2 (en) | 2014-12-03 | 2019-12-30 | Glycomimetics Inc | Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors |
| CA3009836A1 (en) | 2016-01-22 | 2017-07-27 | Glycomimetics, Inc. | Glycomimetic inhibitors of pa-il and pa-iil lectins |
| WO2017151708A1 (en) | 2016-03-02 | 2017-09-08 | Glycomimetics, Inc. | Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin |
| WO2018031445A1 (en) | 2016-08-08 | 2018-02-15 | Glycomimetics, Inc. | Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4 |
| BR112019006642A2 (en) | 2016-10-07 | 2019-07-02 | Glycomimetics Inc | highly potent multimeric e-selectin antagonists |
| CA3054605A1 (en) | 2017-03-15 | 2018-09-20 | Glycomimetics, Inc. | Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists |
| EP3717013A1 (en) | 2017-11-30 | 2020-10-07 | GlycoMimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
| JP7304863B2 (en) | 2017-12-29 | 2023-07-07 | グリコミメティクス， インコーポレイテッド | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| KR20200128025A (en) | 2018-03-05 | 2020-11-11 | 글리코미메틱스, 인크. | Methods of treatment of acute myeloid leukemia and related conditions |
| CN112638944A (en) | 2018-08-23 | 2021-04-09 | 西进公司 | anti-TIGIT antibody |
| AU2019416330A1 (en) | 2018-12-27 | 2021-07-01 | Glycomimetics, Inc. | Galectin-3 inhibiting c-glycosides |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1603609A (en) * | 1977-04-14 | 1981-11-25 | Chembiomed Ltd | O-protected 2-azido-2-deoxy-glycosyl nitrates |
| FR2509313A1 (en) * | 1981-07-08 | 1983-01-14 | Choay Sa | 3-FUCOSYL-N-ACETYL LACTOSAMINE DERIVATIVES, THEIR PREPARATION AND THEIR BIOLOGICAL APPLICATIONS |
| DE3220427A1 (en) * | 1982-05-29 | 1983-12-01 | Behringwerke Ag, 3550 Marburg | SS-D-GALACTOSE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE |
| DK17685D0 (en) * | 1985-01-14 | 1985-01-14 | Hans Goeran Magnusson | glycoside |
| EP0348143A3 (en) * | 1988-06-21 | 1991-03-13 | MARION LABORATORIES, INC. (a Delaware corporation) | Bismuth derivatives of saccharide phosphates and sulphates |
-
1993
- 1993-06-25 DK DK93761A patent/DK76193D0/en not_active Application Discontinuation
-
1994
- 1994-06-17 EP EP94919945A patent/EP0706528A1/en not_active Withdrawn
- 1994-06-17 JP JP7502720A patent/JPH08512026A/en active Pending
- 1994-06-17 CA CA002164961A patent/CA2164961A1/en not_active Abandoned
- 1994-06-17 WO PCT/SE1994/000604 patent/WO1995000527A1/en not_active Ceased
- 1994-06-17 AU AU70891/94A patent/AU7089194A/en not_active Abandoned
- 1994-06-21 IL IL11007494A patent/IL110074A0/en unknown
- 1994-06-22 IS IS4181A patent/IS4181A/en unknown
- 1994-06-27 LT LTIP1978A patent/LT3446B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0706528A1 (en) | 1996-04-17 |
| AU7089194A (en) | 1995-01-17 |
| WO1995000527A1 (en) | 1995-01-05 |
| IS4181A (en) | 1994-12-26 |
| DK76193D0 (en) | 1993-06-25 |
| IL110074A0 (en) | 1994-10-07 |
| LT3446B (en) | 1995-10-25 |
| CA2164961A1 (en) | 1995-01-05 |
| JPH08512026A (en) | 1996-12-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM9A | Lapsed patents |
Effective date: 19960627 |