LTIP1978A - Fucolsylated glycosides as inhibitor of bacterial adherence - Google Patents
Fucolsylated glycosides as inhibitor of bacterial adherenceInfo
- Publication number
- LTIP1978A LTIP1978A LTIP1978A LTIP1978A LTIP1978A LT IP1978 A LTIP1978 A LT IP1978A LT IP1978 A LTIP1978 A LT IP1978A LT IP1978 A LTIP1978 A LT IP1978A LT IP1978 A LTIP1978 A LT IP1978A
- Authority
- LT
- Lithuania
- Prior art keywords
- fucolsylated
- glycosides
- inhibitor
- bacterial adherence
- adherence
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK93761A DK76193D0 (en) | 1993-06-25 | 1993-06-25 | CARBOHYDRATE DERIVATIVES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LTIP1978A true LTIP1978A (en) | 1995-01-31 |
| LT3446B LT3446B (en) | 1995-10-25 |
Family
ID=8097261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTIP1978A LT3446B (en) | 1993-06-25 | 1994-06-27 | Fucolsylated glycosides as inhibitor of bacterial adherence |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0706528A1 (en) |
| JP (1) | JPH08512026A (en) |
| AU (1) | AU7089194A (en) |
| CA (1) | CA2164961A1 (en) |
| DK (1) | DK76193D0 (en) |
| IL (1) | IL110074A0 (en) |
| IS (1) | IS4181A (en) |
| LT (1) | LT3446B (en) |
| WO (1) | WO1995000527A1 (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204431B1 (en) | 1994-03-09 | 2001-03-20 | Abbott Laboratories | Transgenic non-human mammals expressing heterologous glycosyltransferase DNA sequences produce oligosaccharides and glycoproteins in their milk |
| JPH1160590A (en) * | 1997-08-22 | 1999-03-02 | Yakult Honsha Co Ltd | Oligofucose derivative or oligorhamnose derivative and method for producing the same |
| SE9901007D0 (en) * | 1999-03-19 | 1999-03-19 | Thomas Boren | Use of fucosylated sialylated N-acetyl lactosamine carbohydrate structures for inhibition of bacterial adherence |
| JP5175190B2 (en) * | 2005-08-09 | 2013-04-03 | グリコミメティクス， インコーポレイテッド | Pseudomonas-derived PA-IL lectin, PA-IIL lectin or a glycomimetic inhibitor of both lectins |
| US8921328B2 (en) | 2010-09-14 | 2014-12-30 | Glycomimetics, Inc. | E-selectin antagonists |
| SI2794626T1 (en) | 2011-12-22 | 2018-02-28 | Glycomimetics, Inc. | E-selectin antagonist compounds |
| EP2692740A1 (en) * | 2012-07-30 | 2014-02-05 | Le Centre National De La Recherche Scientifique | Glycan compositions, processes for preparing the same and their uses as a drug |
| LT2928476T (en) | 2012-12-07 | 2018-05-25 | Glycomimetics, Inc. | Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells |
| CA2893927A1 (en) * | 2013-01-31 | 2014-08-07 | Pioneer Hi-Bred International, Inc. | Synthetic lipochitooligosaccharides for improvement of plant growth and yield |
| US10086054B2 (en) * | 2013-06-26 | 2018-10-02 | Academia Sinica | RM2 antigens and use thereof |
| HUE045542T2 (en) | 2014-12-03 | 2019-12-30 | Glycomimetics Inc | Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors |
| WO2017127422A1 (en) | 2016-01-22 | 2017-07-27 | Glycomimetics, Inc. | Glycomimetic inhibitors of pa-il and pa-iil lectins |
| WO2017151708A1 (en) | 2016-03-02 | 2017-09-08 | Glycomimetics, Inc. | Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin |
| EP3497131B1 (en) | 2016-08-08 | 2022-03-09 | GlycoMimetics, Inc. | Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4. |
| CA3037850A1 (en) | 2016-10-07 | 2018-04-12 | Glycomimetics, Inc. | Highly potent multimeric e-selectin antagonists |
| CA3054605A1 (en) | 2017-03-15 | 2018-09-20 | Glycomimetics, Inc. | Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists |
| EP3717013A1 (en) | 2017-11-30 | 2020-10-07 | GlycoMimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
| EP3732186A1 (en) | 2017-12-29 | 2020-11-04 | GlycoMimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
| US11707474B2 (en) | 2018-03-05 | 2023-07-25 | Glycomimetics, Inc. | Methods for treating acute myeloid leukemia and related conditions |
| BR112021003156A2 (en) | 2018-08-23 | 2021-05-11 | Seagen, Inc. | composition, antibody that binds to human tigi, pharmaceutical formulation, isolated polynucleotide, vector, host cell, methods for producing an antibody that binds to human tigi and fucosylated antibodies that bind to tigi, and for the treatment of cancer , and, kit. |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| CA3122321A1 (en) | 2018-12-27 | 2020-07-02 | Glycomimetics, Inc. | Galectin-3 inhibiting c-glycosides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1603609A (en) * | 1977-04-14 | 1981-11-25 | Chembiomed Ltd | O-protected 2-azido-2-deoxy-glycosyl nitrates |
| FR2509313A1 (en) * | 1981-07-08 | 1983-01-14 | Choay Sa | 3-FUCOSYL-N-ACETYL LACTOSAMINE DERIVATIVES, THEIR PREPARATION AND THEIR BIOLOGICAL APPLICATIONS |
| DE3220427A1 (en) * | 1982-05-29 | 1983-12-01 | Behringwerke Ag, 3550 Marburg | SS-D-GALACTOSE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE |
| DK17685D0 (en) * | 1985-01-14 | 1985-01-14 | Hans Goeran Magnusson | glycoside |
| AU609999B2 (en) * | 1988-06-21 | 1991-05-09 | Marion Laboratories, Inc. | Bismuth (phosph/sulf)ated saccharides |
-
1993
- 1993-06-25 DK DK93761A patent/DK76193D0/en not_active Application Discontinuation
-
1994
- 1994-06-17 JP JP7502720A patent/JPH08512026A/en active Pending
- 1994-06-17 WO PCT/SE1994/000604 patent/WO1995000527A1/en not_active Ceased
- 1994-06-17 CA CA002164961A patent/CA2164961A1/en not_active Abandoned
- 1994-06-17 AU AU70891/94A patent/AU7089194A/en not_active Abandoned
- 1994-06-17 EP EP94919945A patent/EP0706528A1/en not_active Withdrawn
- 1994-06-21 IL IL11007494A patent/IL110074A0/en unknown
- 1994-06-22 IS IS4181A patent/IS4181A/en unknown
- 1994-06-27 LT LTIP1978A patent/LT3446B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU7089194A (en) | 1995-01-17 |
| LT3446B (en) | 1995-10-25 |
| IL110074A0 (en) | 1994-10-07 |
| IS4181A (en) | 1994-12-26 |
| EP0706528A1 (en) | 1996-04-17 |
| JPH08512026A (en) | 1996-12-17 |
| DK76193D0 (en) | 1993-06-25 |
| CA2164961A1 (en) | 1995-01-05 |
| WO1995000527A1 (en) | 1995-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM9A | Lapsed patents |
Effective date: 19960627 |