IS4181A - Fúkósýleruð glýkósíð sem hindra viðloðun baktería - Google Patents
Fúkósýleruð glýkósíð sem hindra viðloðun bakteríaInfo
- Publication number
- IS4181A IS4181A IS4181A IS4181A IS4181A IS 4181 A IS4181 A IS 4181A IS 4181 A IS4181 A IS 4181A IS 4181 A IS4181 A IS 4181A IS 4181 A IS4181 A IS 4181A
- Authority
- IS
- Iceland
- Prior art keywords
- fucosylated
- glycosides
- bacteria
- inhibit
- adhesion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK93761A DK76193D0 (da) | 1993-06-25 | 1993-06-25 | Kulhydratderivater |
Publications (1)
Publication Number | Publication Date |
---|---|
IS4181A true IS4181A (is) | 1994-12-26 |
Family
ID=8097261
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IS4181A IS4181A (is) | 1993-06-25 | 1994-06-22 | Fúkósýleruð glýkósíð sem hindra viðloðun baktería |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0706528A1 (is) |
JP (1) | JPH08512026A (is) |
AU (1) | AU7089194A (is) |
CA (1) | CA2164961A1 (is) |
DK (1) | DK76193D0 (is) |
IL (1) | IL110074A0 (is) |
IS (1) | IS4181A (is) |
LT (1) | LT3446B (is) |
WO (1) | WO1995000527A1 (is) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6204431B1 (en) | 1994-03-09 | 2001-03-20 | Abbott Laboratories | Transgenic non-human mammals expressing heterologous glycosyltransferase DNA sequences produce oligosaccharides and glycoproteins in their milk |
JPH1160590A (ja) * | 1997-08-22 | 1999-03-02 | Yakult Honsha Co Ltd | オリゴフコース誘導体又はオリゴラムノース誘導体及びその製造法 |
SE9901007D0 (sv) * | 1999-03-19 | 1999-03-19 | Thomas Boren | Use of fucosylated sialylated N-acetyl lactosamin carbohydrate structures for inhibition of bacterial adherence |
ATE528311T1 (de) * | 2005-08-09 | 2011-10-15 | Glycomimetics Inc | Glycomimetische inhibitoren des pa-il-lectins, pa-iil-lectins oder beider lectine aus pseudomonas |
WO2012037034A1 (en) | 2010-09-14 | 2012-03-22 | Glycomimetics, Inc. | E-selectin antagonists |
AU2012358150B2 (en) | 2011-12-22 | 2017-07-20 | Glycomimetics, Inc. | E-selectin antagonist compounds, compositions, and methods of use |
EP2692740A1 (en) * | 2012-07-30 | 2014-02-05 | Le Centre National De La Recherche Scientifique | Glycan compositions, processes for preparing the same and their uses as a drug |
CA2891514C (en) | 2012-12-07 | 2020-08-25 | Glycomimetics, Inc. | Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells |
WO2014120799A1 (en) * | 2013-01-31 | 2014-08-07 | Pioneer Hi-Bred International, Inc. | Synthetic lipochitooligosaccharides for improvement of plant growth and yield |
EP3013365B1 (en) * | 2013-06-26 | 2019-06-05 | Academia Sinica | Rm2 antigens and use thereof |
CA2968391C (en) | 2014-12-03 | 2022-04-26 | Glycomimetics, Inc. | Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors |
WO2017127422A1 (en) | 2016-01-22 | 2017-07-27 | Glycomimetics, Inc. | Glycomimetic inhibitors of pa-il and pa-iil lectins |
US11291678B2 (en) | 2016-03-02 | 2022-04-05 | Glycomimetics, Inc | Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin |
EP3497131B1 (en) | 2016-08-08 | 2022-03-09 | GlycoMimetics, Inc. | Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4. |
JP7069136B2 (ja) | 2016-10-07 | 2022-05-17 | グリコミメティクス, インコーポレイテッド | 極めて強力な多量体e-セレクチンアンタゴニスト |
US11197877B2 (en) | 2017-03-15 | 2021-12-14 | Glycomimetics. Inc. | Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists |
US11712446B2 (en) | 2017-11-30 | 2023-08-01 | Glycomimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
EP3732186A1 (en) | 2017-12-29 | 2020-11-04 | GlycoMimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
CN111867601A (zh) | 2018-03-05 | 2020-10-30 | 糖模拟物有限公司 | 用于治疗急性髓系白血病及相关病症的方法 |
CN112638944A (zh) | 2018-08-23 | 2021-04-09 | 西进公司 | 抗tigit抗体 |
CA3122321A1 (en) | 2018-12-27 | 2020-07-02 | Glycomimetics, Inc. | Galectin-3 inhibiting c-glycosides |
US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1603609A (en) * | 1977-04-14 | 1981-11-25 | Chembiomed Ltd | O-protected 2-azido-2-deoxy-glycosyl nitrates |
FR2509313A1 (fr) * | 1981-07-08 | 1983-01-14 | Choay Sa | Derives de 3-fucosyl-n-acetyl lactosamine, leur preparation et leurs applications biologiques |
DE3220427A1 (de) * | 1982-05-29 | 1983-12-01 | Behringwerke Ag, 3550 Marburg | Ss-d-galactosederivate, verfahren zu ihrer herstellung und ihre verwendung |
DK17685D0 (da) * | 1985-01-14 | 1985-01-14 | Hans Goeran Magnusson | Glycosidderivater |
EP0348143A3 (en) * | 1988-06-21 | 1991-03-13 | MARION LABORATORIES, INC. (a Delaware corporation) | Bismuth derivatives of saccharide phosphates and sulphates |
-
1993
- 1993-06-25 DK DK93761A patent/DK76193D0/da not_active Application Discontinuation
-
1994
- 1994-06-17 CA CA002164961A patent/CA2164961A1/en not_active Abandoned
- 1994-06-17 JP JP7502720A patent/JPH08512026A/ja active Pending
- 1994-06-17 WO PCT/SE1994/000604 patent/WO1995000527A1/en not_active Application Discontinuation
- 1994-06-17 EP EP94919945A patent/EP0706528A1/en not_active Withdrawn
- 1994-06-17 AU AU70891/94A patent/AU7089194A/en not_active Abandoned
- 1994-06-21 IL IL11007494A patent/IL110074A0/xx unknown
- 1994-06-22 IS IS4181A patent/IS4181A/is unknown
- 1994-06-27 LT LTIP1978A patent/LT3446B/lt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1995000527A1 (en) | 1995-01-05 |
DK76193D0 (da) | 1993-06-25 |
CA2164961A1 (en) | 1995-01-05 |
LTIP1978A (en) | 1995-01-31 |
EP0706528A1 (en) | 1996-04-17 |
JPH08512026A (ja) | 1996-12-17 |
IL110074A0 (en) | 1994-10-07 |
LT3446B (en) | 1995-10-25 |
AU7089194A (en) | 1995-01-17 |
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