IN2014MN02213A - - Google Patents
Info
- Publication number
- IN2014MN02213A IN2014MN02213A IN2213MUN2014A IN2014MN02213A IN 2014MN02213 A IN2014MN02213 A IN 2014MN02213A IN 2213MUN2014 A IN2213MUN2014 A IN 2213MUN2014A IN 2014MN02213 A IN2014MN02213 A IN 2014MN02213A
- Authority
- IN
- India
- Prior art keywords
- formulations
- incision
- infiltration
- api
- administered
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Botany (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261645066P | 2012-05-10 | 2012-05-10 | |
| US201261649400P | 2012-05-21 | 2012-05-21 | |
| US201361781625P | 2013-03-14 | 2013-03-14 | |
| US201361781595P | 2013-03-14 | 2013-03-14 | |
| PCT/IL2013/050404 WO2013168167A1 (en) | 2012-05-10 | 2013-05-09 | Depot formulations of a hydrophobic active ingredient and methods for preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN02213A true IN2014MN02213A (forum.php) | 2015-07-10 |
Family
ID=49550270
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2214MUN2014 IN2014MN02214A (forum.php) | 2012-05-10 | 2013-05-09 | |
| IN2213MUN2014 IN2014MN02213A (forum.php) | 2012-05-10 | 2013-05-09 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2214MUN2014 IN2014MN02214A (forum.php) | 2012-05-10 | 2013-05-09 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9849088B2 (forum.php) |
| EP (2) | EP2846772A4 (forum.php) |
| JP (4) | JP2015516411A (forum.php) |
| CN (2) | CN104427977B (forum.php) |
| AU (2) | AU2013257608B2 (forum.php) |
| CA (2) | CA2871820C (forum.php) |
| IN (2) | IN2014MN02214A (forum.php) |
| RU (2) | RU2678433C2 (forum.php) |
| WO (2) | WO2013168167A1 (forum.php) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2846772A4 (en) * | 2012-05-10 | 2015-12-30 | Painreform Ltd | DEPOT FORMULATIONS OF A HYDROPHOBIC ACTIVE SUBSTANCE AND METHOD FOR THE PRODUCTION THEREOF |
| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| LT3331516T (lt) * | 2015-07-13 | 2024-12-27 | Neon Laboratories Ltd. | Ropivakaino hidrochlorido hiperbarinis injekcinis tirpalas ir jo paruošimo procesas |
| CA3078555A1 (en) | 2017-10-06 | 2019-04-11 | Foundry Therapeutics, Inc. | Implantable depots for the controlled release of therapeutic agents |
| US10716774B1 (en) | 2018-01-05 | 2020-07-21 | Yale Pharmaceuticals LLC | Pharmaceutical compositions containing isotretinoin with improved dissolution profile and enhanced stability |
| CN116650732A (zh) | 2018-01-08 | 2023-08-29 | 铸造疗法股份有限公司 | 经由治疗剂的控制递送用于治疗腔内癌症的装置、系统和方法 |
| WO2019226599A1 (en) * | 2018-05-22 | 2019-11-28 | Alkalidx, Inc. | Diagnostics and treatments of anesthetic insensitive subjects |
| EP3843710A1 (en) | 2018-08-28 | 2021-07-07 | Foundry Therapeutics, Inc. | Polymer implants |
| CN109316602A (zh) * | 2018-11-13 | 2019-02-12 | 西安力邦医药科技有限责任公司 | 一种长效镇痛并促进伤口愈合的复方缓释递药系统的组方与应用 |
| JP7378929B2 (ja) * | 2018-12-27 | 2023-11-14 | 花王株式会社 | リポソームの製造方法 |
| CN111388418B (zh) * | 2018-12-31 | 2022-09-06 | 北京泰德制药股份有限公司 | 一种含有罗哌卡因或其药用盐的药物组合物 |
| JP7660079B2 (ja) * | 2019-06-28 | 2025-04-10 | 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 | 徐放脂質組成物及びその製造方法 |
| CN113116813B (zh) * | 2020-01-14 | 2022-11-29 | 中国科学院上海药物研究所 | 一种储库型罗哌卡因药物组合物及其制备方法和用途 |
| CN114762676B (zh) | 2021-01-14 | 2024-03-08 | 南京清普生物科技有限公司 | 一种缓释制剂组合物 |
| US11992483B2 (en) | 2021-03-31 | 2024-05-28 | Cali Biosciences Us, Llc | Emulsions for local anesthetics |
| CN115463084B (zh) * | 2021-06-10 | 2024-05-28 | 北京泰德制药股份有限公司 | 一种长效镇痛用复方油溶液制剂及其制备方法 |
| WO2023043876A1 (en) * | 2021-09-15 | 2023-03-23 | Ocusoft, Inc. | Ointments for treating dry skin |
| WO2024050176A1 (en) * | 2022-08-27 | 2024-03-07 | Rubin Darren Alexander | Injectable methods to treat deficiencies in glutathione metabolism and homocystinuria |
Family Cites Families (114)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4252793A (en) | 1979-06-18 | 1981-02-24 | American Lecithin Company | Injectable lecithin preparation |
| EP0158441B2 (en) | 1984-03-08 | 2001-04-04 | Phares Pharmaceutical Research N.V. | Liposome-forming composition |
| US5173219A (en) | 1986-02-12 | 1992-12-22 | Research Development Foundation | Uniform spherical multilamellar liposomes of defined and adjustable size distribution |
| US5723147A (en) | 1987-02-23 | 1998-03-03 | Depotech Corporation | Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride |
| NZ223660A (en) | 1987-03-05 | 1990-11-27 | Liposome Co Inc | Low toxicity drug-lipid complexes; methods of making them; and method of determining their toxicity |
| CH681427A5 (forum.php) | 1987-07-01 | 1993-03-31 | Zambon Spa | |
| US5807572A (en) | 1988-02-18 | 1998-09-15 | Depotech Corporation | Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride |
| US5576017A (en) | 1988-05-30 | 1996-11-19 | Depotech Corporation | Heterovesicular liposomes |
| US5422120A (en) | 1988-05-30 | 1995-06-06 | Depotech Corporation | Heterovesicular liposomes |
| US5538739A (en) | 1989-07-07 | 1996-07-23 | Sandoz Ltd. | Sustained release formulations of water soluble peptides |
| MY107937A (en) | 1990-02-13 | 1996-06-29 | Takeda Chemical Industries Ltd | Prolonged release microcapsules. |
| AU2699892A (en) | 1991-10-04 | 1993-05-03 | Gs Biochem Ab | Particles, method of preparing said particles and uses thereof |
| SE9200952D0 (sv) * | 1992-03-27 | 1992-03-27 | Kabi Pharmacia Ab | Pharmaceutical carrier system containing defined lipids |
| US5922340A (en) | 1992-09-10 | 1999-07-13 | Children's Medical Center Corporation | High load formulations and methods for providing prolonged local anesthesia |
| SI9300468A (en) | 1992-10-14 | 1994-06-30 | Hoffmann La Roche | Injectable composition for the sustained release of biologically active compounds |
| AU670168B2 (en) | 1992-12-02 | 1996-07-04 | Alkermes Controlled Therapeutics, Inc. | Controlled release growth hormone containing microspheres |
| ATE227979T1 (de) | 1993-04-22 | 2002-12-15 | Skyepharma Inc | Multivesikuläre liposomen mit verkapseltem cyclodextrin und pharmakologisch wirksamen verbindungen sowie verfahren zu deren verwendung |
| US5455044A (en) | 1993-05-14 | 1995-10-03 | Depotech Corporation | Method for treating neurological disorders |
| SE9302218D0 (sv) * | 1993-06-28 | 1993-06-28 | Ab Astra | New use |
| JP3479535B2 (ja) * | 1993-07-08 | 2003-12-15 | ザ リポソーム カンパニー、インコーポレーテッド | リポソームの粒径を制御する方法 |
| RO116341B1 (ro) | 1993-11-16 | 2001-01-30 | Depotech Corp La Jolia | Lipozom multivezicular si procedeu de obtinere a acestuia |
| US5766627A (en) | 1993-11-16 | 1998-06-16 | Depotech | Multivescular liposomes with controlled release of encapsulated biologically active substances |
| JP3645906B2 (ja) | 1993-11-19 | 2005-05-11 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | マイクロカプセル封入された3−ピペリジニル−置換1,2−ベンズイソオキサゾール類及び1,2−ベンズイソチアゾール類 |
| US5635206A (en) | 1994-01-20 | 1997-06-03 | Hoffmann-La Roche Inc. | Process for liposomes or proliposomes |
| US5693337A (en) | 1994-07-13 | 1997-12-02 | Wakamoto Pharmaceutical Co., Ltd. | Stable lipid emulsion |
| US5993850A (en) | 1994-09-13 | 1999-11-30 | Skyepharma Inc. | Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances |
| HU223475B1 (hu) | 1994-10-24 | 2004-07-28 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. | Selegilint tartalmazó liposzoma-készítmény és eljárás ennek előállítására |
| US5660854A (en) | 1994-11-28 | 1997-08-26 | Haynes; Duncan H | Drug releasing surgical implant or dressing material |
| US5955504A (en) | 1995-03-13 | 1999-09-21 | Loma Linda University Medical Center | Colorectal chemoprotective composition and method of preventing colorectal cancer |
| US6160018A (en) | 1995-03-13 | 2000-12-12 | Loma Linda University Medical Center | Prophylactic composition and method for alzheimer's Disease |
| US5981592A (en) | 1995-03-13 | 1999-11-09 | Loma Linda University Medical Center | Method and composition for treating cystic fibrosis |
| US5931809A (en) | 1995-07-14 | 1999-08-03 | Depotech Corporation | Epidural administration of therapeutic compounds with sustained rate of release |
| WO1997007794A1 (en) * | 1995-08-28 | 1997-03-06 | Showa Yakuhin Kako Co., Ltd. | Composition for local anesthesia |
| ES2138130T3 (es) * | 1995-10-28 | 2000-01-01 | Braun Melsungen Ag | Composicion farmaceutica que contiene un anestesico local y/o un analgesico de accion central. |
| US5744337A (en) | 1995-12-26 | 1998-04-28 | The United States Of America As Represented By The Secretary Of The Navy | Internal gelation method for forming multilayer microspheres and product thereof |
| FR2753626B1 (fr) | 1996-09-20 | 1998-11-06 | Centre International De Rech Dermatologiques Galderma Cird Galderma | Nouvelles compositions topiques sous forme d'emulsion fluide h/e a forte teneur en glycol pro-penetrant |
| US5997899A (en) | 1996-10-01 | 1999-12-07 | Skyepharma Inc. | Method for producing liposomes with increased percent of compound encapsulated |
| US5891467A (en) | 1997-01-31 | 1999-04-06 | Depotech Corporation | Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes |
| US6326020B1 (en) * | 1997-05-16 | 2001-12-04 | Children's Medical Center Corporation | Local anesthetic formulations |
| GB2326337A (en) | 1997-06-20 | 1998-12-23 | Phares Pharma Holland | Homogeneous lipid compositions for drug delivery |
| US6306432B1 (en) | 1997-09-08 | 2001-10-23 | Chiron Corporation | High and low load formulations of IGF-I in multivesicular liposomes |
| US6106858A (en) | 1997-09-08 | 2000-08-22 | Skyepharma, Inc. | Modulation of drug loading in multivescular liposomes |
| ES2343767T3 (es) | 1997-09-18 | 2010-08-09 | Pacira Pharmaceuticals, Inc. | Composiciones anestesicas liposomicas de liberacion sostenida. |
| SE512663C2 (sv) | 1997-10-23 | 2000-04-17 | Biogram Ab | Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer |
| ATE286743T1 (de) * | 1997-10-31 | 2005-01-15 | Us Army | Verwendung von inhibitoren der komplementaktivierung zur herstellung eines medikaments zur inhibierung von nebenwirkungen von pharmazeutischen zusammensetzungen, die amphiphile träger oder wirkstoffträger moleküle enthalten |
| WO1999025319A1 (en) | 1997-11-14 | 1999-05-27 | Depotech Corporation | Production of multivesicular liposomes |
| BE1011899A6 (fr) * | 1998-04-30 | 2000-02-01 | Ucb Sa | Compositions pharmaceutiques gelifiables utilisables. |
| AU752225B2 (en) | 1998-07-17 | 2002-09-12 | Pacira Pharmaceuticals, Inc. | Biodegradable compositions for the controlled release of encapsulated substances |
| EP0982035B1 (en) * | 1998-08-18 | 2004-03-31 | Panacea Biotec Limited | Cyclosporin composition comprising an hydrophilic carrier |
| US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| GB9907715D0 (en) | 1999-04-01 | 1999-05-26 | Scherer Corp R P | Pharmaceutical compositions |
| EP1189597A4 (en) | 1999-06-04 | 2008-06-18 | Pacira Pharmaceuticals Inc | COMPOSITIONS USING AN OIL CORE FOR DELAYED RELEASE HYDROPHOLE MEDICAMENTS |
| KR100343125B1 (ko) | 1999-09-14 | 2002-07-05 | 임정옥 | 도포용 리포좀형 혼합국소마취제 및 그 제조방법 |
| EP1138313A1 (de) | 2000-03-28 | 2001-10-04 | Primacare S.A. | Pro-liposomen |
| US6761901B1 (en) | 2000-05-02 | 2004-07-13 | Enzrel Inc. | Liposome drug delivery |
| IL139177A0 (en) | 2000-10-20 | 2001-11-25 | S C Republic Dev S R L | Sustained release drug delivery system |
| CA2447990C (en) | 2001-05-31 | 2012-01-31 | Skyepharma Inc. | Encapsulation of nanosuspensions in liposomes and microspheres |
| US20030099674A1 (en) | 2001-08-11 | 2003-05-29 | Chen Andrew X. | Lyophilized injectable formulations containing paclitaxel or other taxoid drugs |
| AU2002363959B2 (en) | 2001-12-03 | 2007-12-13 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin D compounds |
| AU2003226285B2 (en) | 2002-04-10 | 2008-01-03 | Conforma Therapeutics Corporation | Ansamycin formulations and methods for producing and using same |
| US20030236306A1 (en) | 2002-06-20 | 2003-12-25 | Chen Andrew X. | Stabilized formulations of alpha adrenergic receptor antagonists and the uses thereof |
| US7229630B2 (en) | 2002-06-20 | 2007-06-12 | Novalar Pharmaceuticals, Inc. | Stabilized formulations of alpha adrenergic receptor antagonists and the uses thereof |
| AU2003266159A1 (en) | 2002-09-16 | 2004-04-30 | Zicam, Llc. | System and method for delivering a composition to the nasal membrane |
| WO2004032845A2 (en) | 2002-10-07 | 2004-04-22 | Encore Pharmaceuticals, Inc. | R-nsaid esters and their use |
| US20050026877A1 (en) | 2002-12-03 | 2005-02-03 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin D compounds |
| US20050020546A1 (en) | 2003-06-11 | 2005-01-27 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin D compounds |
| US20060189586A1 (en) | 2003-06-11 | 2006-08-24 | Cleland Jeffrey L | Pharmaceutical compositions comprising active vitamin D compounds |
| US20050049209A1 (en) | 2003-08-06 | 2005-03-03 | Chen Andrew Xian | Pharmaceutical compositions for delivering macrolides |
| US20050118206A1 (en) * | 2003-11-14 | 2005-06-02 | Luk Andrew S. | Surfactant-based gel as an injectable, sustained drug delivery vehicle |
| US7968122B2 (en) | 2003-12-10 | 2011-06-28 | Adventrx Pharmaceuticals, Inc. | Anti-viral pharmaceutical compositions |
| US20050186230A1 (en) | 2004-01-23 | 2005-08-25 | Sd Pharmaceuticals, Inc. | Elemene compositions containing liquid oil |
| EP1729784A1 (en) | 2004-02-23 | 2006-12-13 | Attenuon, LLC | Formulations of thiomolybdate or thiotungstate compounds and uses thereof |
| AU2005249274B2 (en) | 2004-06-04 | 2011-02-24 | Camurus Ab | Liquid depot formulations |
| WO2006002050A1 (en) | 2004-06-15 | 2006-01-05 | Encore Therapeutics, Inc. | Phospholipid compositions and methods for their preparation and use |
| US7871632B2 (en) | 2004-07-12 | 2011-01-18 | Adventrx Pharmaceuticals, Inc. | Compositions for delivering highly water soluble drugs |
| AU2005269383A1 (en) | 2004-07-28 | 2006-02-09 | Sd Pharmaceuticals, Inc. | Stable injectable composition of alpha tocopheryl succinate, analogues and salts thereof |
| US8557861B2 (en) | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
| KR20080039400A (ko) | 2005-07-07 | 2008-05-07 | 파남 컴퍼니스 인크. | 고수용성 약물의 서방성 약학 조성물 |
| WO2007041476A2 (en) * | 2005-09-30 | 2007-04-12 | Vyteris, Inc. | Indications for local transport of anaesthetic agents by electrotransport devices |
| WO2007064968A2 (en) | 2005-12-02 | 2007-06-07 | Adventrx Pharmaceuticals, Inc. | Stable pharmaceutical compositions of 5,10 methylenetetrahydrofolate |
| CN100518738C (zh) * | 2006-01-06 | 2009-07-29 | 中国药科大学 | 一种含喜树碱类药物的自组装前体脂质体及其制备方法 |
| CN100563715C (zh) * | 2006-01-06 | 2009-12-02 | 中国药科大学 | 一种紫杉醇自组装前体脂质体及其制备方法 |
| CN100486569C (zh) * | 2006-01-06 | 2009-05-13 | 中国药科大学 | 一种多烯紫杉醇自组装前体脂质体及其制备方法 |
| TWI376239B (en) | 2006-02-01 | 2012-11-11 | Andrew Xian Chen | Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof |
| JP2010512341A (ja) * | 2006-12-07 | 2010-04-22 | リオトロピック セラピュティックス アイエヌシー. | 麻酔薬および他の化合物の逆転および解毒用組成物ならびにその使用方法 |
| EP1938801A1 (en) | 2006-12-22 | 2008-07-02 | Biofrontera Bioscience GmbH | Nanoemulsion |
| US20100041704A1 (en) | 2007-01-12 | 2010-02-18 | Aberg A K Gunnar | Dermal compositions of substituted amides and the use thereof as medication for pain and pruritus |
| CN101652128B (zh) | 2007-03-02 | 2012-12-19 | 法纳姆公司 | 使用蜡状材料的缓释组合物 |
| WO2008114274A1 (en) | 2007-03-19 | 2008-09-25 | Fresenius Kabi Onclology Ltd. | Proliposomal and liposomal compositions |
| BRPI0704542B8 (pt) | 2007-05-15 | 2021-05-25 | Univ Estadual Campinas Unicamp | composição farmacêutica, processo de obtenção da composição farmacêutica, uso de uma quantidade farmaceuticamente eficaz de anestésico e agente gelificante, produto e método de tratamento |
| RU2429242C2 (ru) | 2007-05-30 | 2011-09-20 | Учреждение Российской Академии Наук Институт Проблем Химической Физики Ран (Ипхф Ран) | Применение тетранитрозильного комплекса железа с тиофенолом в качестве противоопухолевого лекарственного средства |
| HUP0700426A2 (en) | 2007-06-19 | 2010-03-29 | Invencio 21 Gyogyhatasu Keszit | Liposomal compound |
| EP2178893A4 (en) | 2007-07-16 | 2012-09-19 | Poniard Pharmaceuticals Inc | ORAL FORMULATIONS FOR PICOPLATIN |
| FR2924024B1 (fr) | 2007-11-27 | 2012-08-17 | Centre Nat Rech Scient | Nanoparticules d'actifs therapeutiques de faible solubilite aqueuse |
| CN101485629B (zh) | 2008-01-16 | 2013-01-23 | 沈阳药科大学 | 一种给药系统及其制备方法 |
| JP5608653B2 (ja) | 2008-09-04 | 2014-10-15 | ファーナム・カンパニーズ・インコーポレーテッド | チュアブルな徐放性製剤 |
| CN102202672A (zh) | 2008-10-10 | 2011-09-28 | 达拉生物科学公司 | 使用穗霉素衍生物治疗或预防疼痛的方法 |
| WO2010138918A1 (en) | 2009-05-29 | 2010-12-02 | Pacira Pharmaceuticals, Inc. | Hyaluronidase as an adjuvant for increasing the injection volume and dispersion of large diameter synthetic membrane vesicles containing a therapeutic agent |
| WO2011031462A2 (en) | 2009-08-25 | 2011-03-17 | Latitude Pharmaceuticals Incorporated | Compositions for delivery of insoluble agents |
| WO2011075623A1 (en) | 2009-12-18 | 2011-06-23 | Latitude Pharmaceuticals, Inc. | One - phase gel compos ition compri s ing phos pholi pids |
| EP2336286A1 (en) * | 2009-12-18 | 2011-06-22 | The Procter & Gamble Company | Composition comprising microcapsules |
| WO2011096953A1 (en) | 2010-02-05 | 2011-08-11 | Cenerx Biopharma, Inc. | Oral antidepressant formulation with reduced excipient load |
| CN102892408A (zh) | 2010-04-01 | 2013-01-23 | 帕玛内斯特公司 | 适于局部麻醉剂的无水药物组合物 |
| JP6043278B2 (ja) | 2010-04-09 | 2016-12-14 | パシラ ファーマシューティカルズ インコーポレーテッド | 多小胞リポソームを作製するための方法、大直径合成膜小胞を調製するための方法、および蒸発装置 |
| US9770414B2 (en) | 2010-05-13 | 2017-09-26 | Pacira Pharmaceuticals, Inc. | Sustained release formulation of methotrexate as a disease-modifying antirheumatic drug (DMARD) and an anti-cancer agent |
| WO2011153513A2 (en) | 2010-06-03 | 2011-12-08 | Latitude Pharma | Nanoemulsion composition containing vitamin k |
| AU2011276552B2 (en) | 2010-06-29 | 2015-09-03 | Verastem, Inc. | Oral formulation of kinase inhibitors |
| US8697746B2 (en) | 2010-07-14 | 2014-04-15 | Senju Pharmaceutical Co., Ltd. | Solid dispersion of alpha-ketoamide derivatives |
| CA2809022C (en) | 2010-08-20 | 2017-01-03 | Dr. Reddy`S Laboratories, Inc. | Phospholipid depot |
| US20130203701A1 (en) | 2010-09-17 | 2013-08-08 | Maine Natural Health, Inc. | Compositions containing omega-3 oil and uses thereof |
| AU2011317237B2 (en) | 2010-10-22 | 2015-02-05 | Dr. Reddy's Laboratories Sa | Use of storage stable viscous phospholipid depot to treat wounds |
| US10610486B2 (en) | 2010-10-28 | 2020-04-07 | Pacira Pharmaceuticals, Inc. | Sustained release formulation of a non-steroidal anti-inflammatory drug |
| AU2012267721A1 (en) | 2011-06-09 | 2013-12-19 | Amylin Pharmaceuticals, Llc | Gel compositions |
| EP2846772A4 (en) * | 2012-05-10 | 2015-12-30 | Painreform Ltd | DEPOT FORMULATIONS OF A HYDROPHOBIC ACTIVE SUBSTANCE AND METHOD FOR THE PRODUCTION THEREOF |
-
2013
- 2013-05-09 EP EP13787409.5A patent/EP2846772A4/en active Pending
- 2013-05-09 IN IN2214MUN2014 patent/IN2014MN02214A/en unknown
- 2013-05-09 CA CA2871820A patent/CA2871820C/en active Active
- 2013-05-09 JP JP2015510942A patent/JP2015516411A/ja active Pending
- 2013-05-09 RU RU2014144501A patent/RU2678433C2/ru active
- 2013-05-09 JP JP2015510944A patent/JP2015516412A/ja active Pending
- 2013-05-09 US US14/399,884 patent/US9849088B2/en active Active
- 2013-05-09 AU AU2013257608A patent/AU2013257608B2/en active Active
- 2013-05-09 CN CN201380036700.XA patent/CN104427977B/zh active Active
- 2013-05-09 RU RU2014144500A patent/RU2664700C2/ru active
- 2013-05-09 IN IN2213MUN2014 patent/IN2014MN02213A/en unknown
- 2013-05-09 US US14/399,815 patent/US9668974B2/en active Active
- 2013-05-09 CA CA2871821A patent/CA2871821C/en active Active
- 2013-05-09 WO PCT/IL2013/050404 patent/WO2013168167A1/en active Application Filing
- 2013-05-09 AU AU2013257546A patent/AU2013257546B2/en active Active
- 2013-05-09 CN CN201380036669.XA patent/CN104427976B/zh active Active
- 2013-05-09 WO PCT/IL2013/050410 patent/WO2013168172A1/en active Application Filing
- 2013-05-09 EP EP13787930.0A patent/EP2846773A4/en active Pending
-
2017
- 2017-05-02 US US15/584,391 patent/US10206876B2/en active Active
- 2017-10-03 JP JP2017193516A patent/JP6574228B2/ja active Active
- 2017-10-04 JP JP2017194260A patent/JP6577548B2/ja active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2014MN02213A (forum.php) | ||
| AU2018256640A1 (en) | Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives | |
| MX2021006035A (es) | Formulaciones cannabinoides estables. | |
| MX2016005395A (es) | Formulacion estable de insulina glulisina. | |
| MX2014011181A (es) | Microemulsiones basadas en ciclodextrina y usos dermatologicos de las mismas. | |
| MX2015017964A (es) | Inhibidores de bromodominio. | |
| MX388963B (es) | Formulacion farmaceutica acuosa de tapentadol para administracion oral | |
| MD20150050A2 (ro) | Soluţii midriatice şi antiinflamatorii stabile fără conservanţi pentru injectare | |
| IN2014MN01470A (forum.php) | ||
| EP4360621A3 (en) | Formulations of bendamustine | |
| IN2014DN00277A (forum.php) | ||
| JO3683B1 (ar) | صياغة صلبة عبر الفم تحتوي على إرينوتيكان وطريقة لتحضيرها | |
| MX384877B (es) | Composiciones de éster de colina de ácido lipoico y métodos de uso. | |
| MX2016015211A (es) | Formulaciones topicas y usos de las mismas. | |
| PH12015502556A1 (en) | Modified release formulation | |
| EP2981258B8 (en) | Pharmaceutical formulations for subcutaneous administration of furosemide | |
| JO3587B1 (ar) | أشكال جرعات بينداموستين عن طريق الفم | |
| WO2013100869A3 (en) | Lipid-based nanocarrier systems for using cancer treatment | |
| IN2014DN09246A (forum.php) | ||
| GB201204632D0 (en) | Delivery system | |
| BR112017019364A2 (pt) | dispersões sólidas | |
| EP2668952A3 (en) | Aqueous formulations of bisphosphonates, vitamin D and benzyl alcohol suitable for subcutaneous or intramuscular use | |
| EA201491477A1 (ru) | Фармацевтические составы, содержащие флупиртин | |
| EP3010534A4 (en) | Pharmaceutical formulations and methods for oral delivery of biologically active ingredient | |
| IN2013MU03544A (forum.php) |