IN2014KN00866A - - Google Patents

Info

Publication number
IN2014KN00866A
IN2014KN00866A IN866KON2014A IN2014KN00866A IN 2014KN00866 A IN2014KN00866 A IN 2014KN00866A IN 866KON2014 A IN866KON2014 A IN 866KON2014A IN 2014KN00866 A IN2014KN00866 A IN 2014KN00866A
Authority
IN
India
Prior art keywords
amino acid
seq
acid sequence
hydantoinase
catalytic activity
Prior art date
Application number
Other languages
English (en)
Inventor
Steffen Osswald
Heiko Schuster
Jürgen Roos
Andreas Karau
Ulrich Schwaneberg
Ronny Martinez
Hemanshu Mundhada
Ursula Holter
Original Assignee
Evonik Industries Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Industries Ag filed Critical Evonik Industries Ag
Publication of IN2014KN00866A publication Critical patent/IN2014KN00866A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/22Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227Tryptophan
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/009Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y305/00Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/02Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amides (3.5.2)
    • C12Y305/02002Dihydropyrimidinase (3.5.2.2), i.e. hydantoinase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IN866KON2014 2011-11-16 2012-11-16 IN2014KN00866A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11189395 2011-11-16
PCT/EP2012/072891 WO2013072486A1 (en) 2011-11-16 2012-11-16 Mutants of hydantoinase

Publications (1)

Publication Number Publication Date
IN2014KN00866A true IN2014KN00866A (ja) 2015-10-02

Family

ID=47189946

Family Applications (1)

Application Number Title Priority Date Filing Date
IN866KON2014 IN2014KN00866A (ja) 2011-11-16 2012-11-16

Country Status (12)

Country Link
US (2) US9957536B2 (ja)
EP (1) EP2780451B1 (ja)
JP (1) JP6279478B2 (ja)
KR (1) KR102027201B1 (ja)
CN (2) CN104053772A (ja)
BR (1) BR112014011664A2 (ja)
CA (1) CA2856127C (ja)
DK (1) DK2780451T3 (ja)
ES (1) ES2652387T3 (ja)
IN (1) IN2014KN00866A (ja)
PL (1) PL2780451T3 (ja)
WO (1) WO2013072486A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112175929A (zh) * 2020-10-10 2021-01-05 山西大学 一种重组海因消旋酶工程菌及其构建方法和用途
EP4105335A1 (en) 2021-06-16 2022-12-21 Evonik Operations GmbH Enzymatic method for the production of l-glufosinate p-alkyl esters
WO2023174511A1 (en) 2022-03-14 2023-09-21 Evonik Operations Gmbh Enzymatic method for the production of l-glufosinate p-esters
WO2023222226A1 (en) 2022-05-19 2023-11-23 Evonik Operations Gmbh Enzymatic method for producing l-glufosinate
WO2023222227A1 (en) 2022-05-19 2023-11-23 Evonik Operations Gmbh Enzymatic method for producing l-glufosinate
WO2023232225A1 (en) 2022-05-31 2023-12-07 Evonik Operations Gmbh Enzymatic method for the diastereoselective production of l-glufosinate p-esters

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5391189A (en) * 1976-12-30 1978-08-10 Kanegafuchi Chem Ind Co Ltd Preparation of d-n-carbamoyl-alpha-amino acids
JPS6225990A (ja) * 1986-07-19 1987-02-03 Kanegafuchi Chem Ind Co Ltd D−α−アミノ酸類の製造方法
DE4316928C2 (de) 1993-05-19 1995-03-16 Degussa Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
US6524837B1 (en) * 1999-03-29 2003-02-25 California Institute Of Technology Hydantoinase variants with improved properties and their use for the production of amino acids
DE10114999A1 (de) 2001-03-26 2002-10-10 Degussa D-Carbamoylase aus Arthrobacter crystallopoietes DSM 20117
DE10155928A1 (de) 2001-11-15 2003-06-12 Degussa recA-negativer und rhaB-negativer Mikroorganismus
CN1260347C (zh) * 2002-05-13 2006-06-21 中国人民解放军军事医学科学院生物工程研究所 一株产乙内酰脲酶系的节杆菌
DE10251184A1 (de) 2002-11-04 2004-05-13 Degussa Ag Mutanten zur Herstellung von D-Aminosäuren
JP2007189949A (ja) * 2006-01-19 2007-08-02 Kaneka Corp 新規ヒダントイナーゼ及び光学活性アミノ酸誘導体の製造方法

Also Published As

Publication number Publication date
CN109468304A (zh) 2019-03-15
WO2013072486A1 (en) 2013-05-23
US20150056667A1 (en) 2015-02-26
JP2014533497A (ja) 2014-12-15
KR102027201B1 (ko) 2019-10-01
BR112014011664A2 (pt) 2017-05-09
PL2780451T3 (pl) 2018-03-30
CN109468304B (zh) 2022-04-19
DK2780451T3 (en) 2018-01-02
CA2856127C (en) 2021-04-06
JP6279478B2 (ja) 2018-02-14
KR20140092835A (ko) 2014-07-24
EP2780451B1 (en) 2017-09-20
US10822627B2 (en) 2020-11-03
EP2780451A1 (en) 2014-09-24
ES2652387T3 (es) 2018-02-01
CN104053772A (zh) 2014-09-17
US20180237814A1 (en) 2018-08-23
CA2856127A1 (en) 2013-05-23
US9957536B2 (en) 2018-05-01

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