IN2014DN10670A - - Google Patents
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- Publication number
- IN2014DN10670A IN2014DN10670A IN10670DEN2014A IN2014DN10670A IN 2014DN10670 A IN2014DN10670 A IN 2014DN10670A IN 10670DEN2014 A IN10670DEN2014 A IN 10670DEN2014A IN 2014DN10670 A IN2014DN10670 A IN 2014DN10670A
- Authority
- IN
- India
- Prior art keywords
- compound
- treating
- formula
- methods
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261660428P | 2012-06-15 | 2012-06-15 | |
| US201261678795P | 2012-08-02 | 2012-08-02 | |
| PCT/US2013/045919 WO2013188783A1 (en) | 2012-06-15 | 2013-06-14 | Deuterated derivatives of ruxolitinib |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN10670A true IN2014DN10670A (zh) | 2015-08-28 |
Family
ID=48699982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN10670DEN2014 IN2014DN10670A (zh) | 2012-06-15 | 2013-06-14 |
Country Status (11)
| Country | Link |
|---|---|
| EP (3) | EP3450434B1 (zh) |
| AU (3) | AU2013274030B2 (zh) |
| BR (2) | BR112014031204A2 (zh) |
| CA (1) | CA2876306C (zh) |
| DK (1) | DK3450434T3 (zh) |
| EA (1) | EA201492287A1 (zh) |
| ES (1) | ES2867048T3 (zh) |
| IN (1) | IN2014DN10670A (zh) |
| MX (1) | MX360495B (zh) |
| PL (1) | PL3450434T3 (zh) |
| WO (1) | WO2013188783A1 (zh) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2612196T3 (es) | 2005-12-13 | 2017-05-12 | Incyte Holdings Corporation | Pirrolo[2,3-b]piridinas y pirrolo[2,3-b]pirimidinas sustituidas con heteroarilo como inhibidores de quinasas Janus |
| KR102354472B1 (ko) | 2010-03-10 | 2022-01-21 | 인사이트 홀딩스 코포레이션 | Ｊａｋ１ 저해제로서의 피페리딘４일 아제티딘 유도체 |
| JP5876146B2 (ja) | 2011-06-20 | 2016-03-02 | インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ | Ｊａｋ阻害剤としてのアゼチジニルフェニル、ピリジル、またはピラジニルカルボキサミド誘導体 |
| US20150197525A1 (en) | 2012-06-15 | 2015-07-16 | Concert Pharmaceuticals, Inc. | Deuterated derivatives of ruxolitinib |
| IN2014DN10670A (zh) | 2012-06-15 | 2015-08-28 | Concert Pharmaceuticals Inc | |
| HUE055894T2 (hu) | 2012-11-15 | 2021-12-28 | Incyte Holdings Corp | A ruxolitinib nyújtott felszabadulású dózisformái |
| EP3721873A1 (en) | 2013-08-07 | 2020-10-14 | Incyte Corporation | Sustained release dosage forms for a jak1 inhibitor |
| EP3148545B1 (en) | 2014-05-28 | 2023-03-15 | Onco Tracker, Inc. | Anti-cancer effects of jak2 inhibitors in combination with thalidomide derivatives and glucocorticoids |
| US11033490B2 (en) * | 2016-12-14 | 2021-06-15 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a JAK inhibitor and devices |
| AR113922A1 (es) | 2017-12-08 | 2020-07-01 | Incyte Corp | Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas |
| KR20210124345A (ko) * | 2019-02-06 | 2021-10-14 | 콘서트 파마슈티컬즈, 인크. | 거울상 이성질체 풍부한 jak 억제제를 제조하는 방법 |
| WO2021236139A1 (en) | 2020-05-21 | 2021-11-25 | Concert Pharmaceuticals, Inc. | Novel deuterated jak inhibitor and uses thereof |
| US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
| CA3228505A1 (en) | 2021-08-11 | 2023-02-16 | Sun Pharmaceutical Industries, Inc. | Treatment of hair loss disorders with deuterated jak inhibitors |
| WO2023018954A1 (en) | 2021-08-12 | 2023-02-16 | Concert Pharmaceuticals, Inc. | Treatment of jak-inhibition-responsive disorders with prodrugs of jak inhibitors |
| CN117384163A (zh) * | 2022-07-05 | 2024-01-12 | 盛世泰科生物医药技术(苏州)股份有限公司 | 一种含偕二氟基的化合物及其制备方法和用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5304121A (en) | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
| US5886026A (en) | 1993-07-19 | 1999-03-23 | Angiotech Pharmaceuticals Inc. | Anti-angiogenic compositions and methods of use |
| US6099562A (en) | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| GB9925962D0 (en) | 1999-11-02 | 1999-12-29 | Novartis Ag | Organic compounds |
| HU229938B1 (en) | 2001-05-03 | 2015-01-28 | Hoffmann La Roche | Pharmaceutical dosage form of amorphous nelfinavir mesylate |
| EP1392262A1 (en) | 2001-05-24 | 2004-03-03 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
| WO2006039237A1 (en) | 2004-09-29 | 2006-04-13 | Cordis Corporation | Pharmaceutical dosage forms of stable amorphous rapamycin like compounds |
| ES2612196T3 (es) * | 2005-12-13 | 2017-05-12 | Incyte Holdings Corporation | Pirrolo[2,3-b]piridinas y pirrolo[2,3-b]pirimidinas sustituidas con heteroarilo como inhibidores de quinasas Janus |
| CL2008001709A1 (es) | 2007-06-13 | 2008-11-03 | Incyte Corp | Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras. |
| WO2009094216A1 (en) | 2008-01-22 | 2009-07-30 | Concert Pharmaceuticals Inc. | Derivatives of gefitinib |
| JOP20190230A1 (ar) | 2009-01-15 | 2017-06-16 | Incyte Corp | طرق لاصلاح مثبطات انزيم jak و المركبات الوسيطة المتعلقة به |
| IN2014DN10670A (zh) | 2012-06-15 | 2015-08-28 | Concert Pharmaceuticals Inc | |
| HUE055894T2 (hu) * | 2012-11-15 | 2021-12-28 | Incyte Holdings Corp | A ruxolitinib nyújtott felszabadulású dózisformái |
-
2013
- 2013-06-14 IN IN10670DEN2014 patent/IN2014DN10670A/en unknown
- 2013-06-14 ES ES18188152T patent/ES2867048T3/es active Active
- 2013-06-14 CA CA2876306A patent/CA2876306C/en active Active
- 2013-06-14 EP EP18188152.5A patent/EP3450434B1/en active Active
- 2013-06-14 EP EP13732046.1A patent/EP2861600A1/en not_active Withdrawn
- 2013-06-14 WO PCT/US2013/045919 patent/WO2013188783A1/en active Application Filing
- 2013-06-14 DK DK18188152.5T patent/DK3450434T3/da active
- 2013-06-14 PL PL18188152T patent/PL3450434T3/pl unknown
- 2013-06-14 EP EP21156398.6A patent/EP3882249A1/en active Pending
- 2013-06-14 AU AU2013274030A patent/AU2013274030B2/en active Active
- 2013-06-14 MX MX2014015185A patent/MX360495B/es active IP Right Grant
- 2013-06-14 EA EA201492287A patent/EA201492287A1/ru unknown
- 2013-06-14 BR BR112014031204A patent/BR112014031204A2/pt active Search and Examination
- 2013-06-14 BR BR122023027277-3A patent/BR122023027277A2/pt unknown
-
2016
- 2016-10-05 AU AU2016238877A patent/AU2016238877B2/en active Active
-
2018
- 2018-11-26 AU AU2018271227A patent/AU2018271227B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| MX360495B (es) | 2018-11-06 |
| EP3450434B1 (en) | 2021-02-24 |
| CA2876306C (en) | 2024-02-20 |
| EP3882249A1 (en) | 2021-09-22 |
| AU2013274030B2 (en) | 2016-07-07 |
| DK3450434T3 (da) | 2021-05-03 |
| EA201492287A1 (ru) | 2015-07-30 |
| BR112014031204A2 (pt) | 2017-06-27 |
| WO2013188783A8 (en) | 2014-02-27 |
| AU2018271227A1 (en) | 2018-12-13 |
| AU2016238877B2 (en) | 2018-08-30 |
| AU2018271227B2 (en) | 2020-08-27 |
| EP3450434A1 (en) | 2019-03-06 |
| MX2014015185A (es) | 2015-02-17 |
| CA2876306A1 (en) | 2013-12-19 |
| BR122023027277A2 (pt) | 2024-01-23 |
| EP2861600A1 (en) | 2015-04-22 |
| AU2013274030A1 (en) | 2015-01-22 |
| PL3450434T3 (pl) | 2021-10-04 |
| AU2016238877A1 (en) | 2016-10-27 |
| ES2867048T3 (es) | 2021-10-20 |
| WO2013188783A1 (en) | 2013-12-19 |
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