IN2014DN00185A - - Google Patents
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- Publication number
- IN2014DN00185A IN2014DN00185A IN185DEN2014A IN2014DN00185A IN 2014DN00185 A IN2014DN00185 A IN 2014DN00185A IN 185DEN2014 A IN185DEN2014 A IN 185DEN2014A IN 2014DN00185 A IN2014DN00185 A IN 2014DN00185A
- Authority
- IN
- India
- Prior art keywords
- formula
- alzheimer
- salt
- compound represented
- diagnostic agent
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- 210000004556 brain Anatomy 0.000 abstract 2
- 229940039227 diagnostic agent Drugs 0.000 abstract 2
- 239000000032 diagnostic agent Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000002349 favourable effect Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000002285 radioactive effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011140069 | 2011-06-24 | ||
| PCT/JP2012/063726 WO2012176587A1 (ja) | 2011-06-24 | 2012-05-29 | 新規アミロイド親和性化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN00185A true IN2014DN00185A (enExample) | 2015-07-10 |
Family
ID=47422429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN185DEN2014 IN2014DN00185A (enExample) | 2011-06-24 | 2012-05-29 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9211350B2 (enExample) |
| EP (1) | EP2725027B1 (enExample) |
| JP (1) | JP5167436B2 (enExample) |
| KR (1) | KR101854228B1 (enExample) |
| CN (1) | CN103596950B (enExample) |
| AU (1) | AU2012274639B2 (enExample) |
| CA (1) | CA2839199C (enExample) |
| ES (1) | ES2619830T3 (enExample) |
| IN (1) | IN2014DN00185A (enExample) |
| TW (1) | TWI554511B (enExample) |
| WO (1) | WO2012176587A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3197277T3 (pl) * | 2014-08-29 | 2022-04-04 | Chdi Foundation, Inc. | Sondy do obrazowania molekularnego białka huntingtyny |
| WO2019056098A1 (en) * | 2017-09-19 | 2019-03-28 | The Governors Of The University Of Alberta | BIOREDUCTION-ACTIVATED COMPOUNDS, THEIR PRODRUGS, RADIOPHARMACEUTICAL PRODUCTS, COMPOSITIONS AND THEIR APPLICATIONS IN THE MULTIMODAL THERANOSTIC MANAGEMENT OF HYPOXIA, INCLUDING CANCER |
| JP6831802B2 (ja) * | 2018-01-12 | 2021-02-17 | 上海富吉医療器械有限公司Ｓｈａｎｇｈａｉ Ｃｈａｒｔｗｅｌｌ Ｍｅｄｉｃａｌ Ｉｎｓｔｒｕｍｅｎｔ Ｃｏ．， Ｌｔｄ． | 放射性核種標識化合物及びこれを含有するイメージング剤 |
| WO2022244680A1 (ja) * | 2021-05-18 | 2022-11-24 | 国立大学法人大阪大学 | 画像診断用磁気ナノ粒子及び画像診断用造影剤 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1105163A4 (en) | 1998-08-20 | 2003-05-02 | Univ California | METHOD FOR MARKING AMYLOID PLAQUES AND NEUROFIBRILLIC GIFTS |
| RU2324686C2 (ru) | 2000-08-24 | 2008-05-20 | Юнивесити Оф Питсбэг | ПРОИЗВОДНЫЕ ТИОФЛАВИНА, СВЯЗЫВАЮЩИЕ АМИЛОИД, СПОСОБ ОБНАРУЖЕНИЯ in vivo ОТЛОЖЕНИЙ АМИЛОИДА И СПОСОБ РАСПОЗНАВАНИЯ БОЛЕЗНИ АЛЬЦГЕЙМЕРА |
| CA2444214A1 (en) | 2001-04-23 | 2002-10-31 | The Trustees Of The University Of Pennsylvania | Amyloid plaque aggregation inhibitors and diagnostic imaging agents |
| AU2002323417B2 (en) | 2001-08-27 | 2008-05-15 | The Trustees Of The University Of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
| WO2007033080A2 (en) * | 2005-09-12 | 2007-03-22 | Emory University | Alzheimer's disease imaging agents |
| US8022075B2 (en) * | 2005-11-30 | 2011-09-20 | Fujifilm Ri Pharma Co., Ltd. | Diagnostic and remedy for disease caused by amyloid aggregation and/or deposition |
| JP5238496B2 (ja) | 2006-05-19 | 2013-07-17 | 日本メジフィジックス株式会社 | 新規アミロイド親和性化合物 |
| CN101501033B (zh) | 2006-06-21 | 2012-08-01 | 通用电气医疗有限公司 | 对淀粉状蛋白具有亲和性的化合物 |
| CN101595108A (zh) | 2006-11-30 | 2009-12-02 | 日本医事物理股份有限公司 | 对淀粉状蛋白具有亲和性的新化合物 |
| AU2008208091A1 (en) | 2007-01-22 | 2008-07-31 | Astrazeneca Ab | Novel heteroaryl substituted imidazo [1,2 -a] pyridine derivatives |
| TW200918102A (en) | 2007-10-24 | 2009-05-01 | Nihon Mediphysics Co Ltd | Novel compound having affinity for amyloid |
| CN101903383A (zh) | 2007-10-26 | 2010-12-01 | 日本医事物理股份有限公司 | 对淀粉样蛋白具有亲和性的新化合物 |
| KR20100101577A (ko) * | 2007-10-30 | 2010-09-17 | 니혼 메디피직스 가부시키가이샤 | 신규 아밀로이드 친화성 화합물의 사용 및 제조 방법 |
| CA2704168A1 (en) | 2007-10-30 | 2009-05-07 | Nihon Medi-Physics Co., Ltd. | Use of novel compound having affinity for amyloid, and process for production of the same |
| KR20100089858A (ko) | 2007-10-30 | 2010-08-12 | 니혼 메디피직스 가부시키가이샤 | 신규 아밀로이드 친화성 화합물의 사용 및 제조 방법 |
| EP2296474A1 (en) * | 2008-05-30 | 2011-03-23 | Merck Sharp & Dohme Corp. | Novel substituted indoles |
| EP2218464A1 (en) * | 2009-02-11 | 2010-08-18 | Technische Universität München | Compounds for non-invasive measurement of aggregates of amyloid peptides |
| JPWO2010128595A1 (ja) * | 2009-05-07 | 2012-11-01 | 富士フイルムＲｉファーマ株式会社 | 放射性ヨウ素標識イミダゾピリジン誘導体の製造法 |
| US20120263646A1 (en) | 2009-10-15 | 2012-10-18 | Guerbet | Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases |
| KR20140040722A (ko) * | 2011-05-20 | 2014-04-03 | 니혼 메디피직스 가부시키가이샤 | 신규 아밀로이드 친화성 화합물 |
-
2012
- 2012-05-29 IN IN185DEN2014 patent/IN2014DN00185A/en unknown
- 2012-05-29 KR KR1020137032274A patent/KR101854228B1/ko not_active Expired - Fee Related
- 2012-05-29 AU AU2012274639A patent/AU2012274639B2/en not_active Ceased
- 2012-05-29 CA CA2839199A patent/CA2839199C/en not_active Expired - Fee Related
- 2012-05-29 CN CN201280027545.0A patent/CN103596950B/zh active Active
- 2012-05-29 US US14/128,903 patent/US9211350B2/en active Active
- 2012-05-29 ES ES12802179.7T patent/ES2619830T3/es active Active
- 2012-05-29 JP JP2012540219A patent/JP5167436B2/ja active Active
- 2012-05-29 WO PCT/JP2012/063726 patent/WO2012176587A1/ja not_active Ceased
- 2012-05-29 EP EP12802179.7A patent/EP2725027B1/en active Active
- 2012-05-31 TW TW101119585A patent/TWI554511B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| TWI554511B (zh) | 2016-10-21 |
| TW201300388A (zh) | 2013-01-01 |
| WO2012176587A1 (ja) | 2012-12-27 |
| CA2839199A1 (en) | 2012-12-27 |
| KR101854228B1 (ko) | 2018-05-03 |
| EP2725027A1 (en) | 2014-04-30 |
| AU2012274639A1 (en) | 2014-02-06 |
| KR20140040735A (ko) | 2014-04-03 |
| US9211350B2 (en) | 2015-12-15 |
| US20140121377A1 (en) | 2014-05-01 |
| CA2839199C (en) | 2018-11-06 |
| AU2012274639B2 (en) | 2016-08-11 |
| CN103596950B (zh) | 2017-12-19 |
| CN103596950A (zh) | 2014-02-19 |
| JPWO2012176587A1 (ja) | 2015-02-23 |
| JP5167436B2 (ja) | 2013-03-21 |
| ES2619830T3 (es) | 2017-06-27 |
| EP2725027A4 (en) | 2015-02-25 |
| EP2725027B1 (en) | 2017-03-01 |
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