IN2014DE00737A - - Google Patents

Info

Publication number
IN2014DE00737A
IN2014DE00737A IN737DE2014A IN2014DE00737A IN 2014DE00737 A IN2014DE00737 A IN 2014DE00737A IN 737DE2014 A IN737DE2014 A IN 737DE2014A IN 2014DE00737 A IN2014DE00737 A IN 2014DE00737A
Authority
IN
India
Prior art keywords
solvent
branched
alcohol
linear
water content
Prior art date
Application number
Other languages
English (en)
Inventor
Alexander Zabudkin
Victor Matvienko
Alexey Matvyeyev
Original Assignee
Synbias Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synbias Pharma Ltd filed Critical Synbias Pharma Ltd
Publication of IN2014DE00737A publication Critical patent/IN2014DE00737A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • A61K31/015Hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
IN737DE2014 2013-03-15 2014-03-13 IN2014DE00737A (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361787097P 2013-03-15 2013-03-15
EP13159392.3A EP2778171A1 (en) 2013-03-15 2013-03-15 Crystalline monohydrate of epirubicin hydrochloride

Publications (1)

Publication Number Publication Date
IN2014DE00737A true IN2014DE00737A (ro) 2015-06-19

Family

ID=48013735

Family Applications (1)

Application Number Title Priority Date Filing Date
IN737DE2014 IN2014DE00737A (ro) 2013-03-15 2014-03-13

Country Status (15)

Country Link
US (2) US20140271874A1 (ro)
EP (2) EP2778171A1 (ro)
JP (1) JP5964339B2 (ro)
KR (1) KR101751099B1 (ro)
CN (1) CN104045672B (ro)
DK (1) DK2778172T3 (ro)
ES (1) ES2623218T3 (ro)
HK (1) HK1199264A1 (ro)
HU (1) HUE034152T2 (ro)
IN (1) IN2014DE00737A (ro)
PL (1) PL2778172T3 (ro)
PT (1) PT2778172T (ro)
RS (1) RS55850B1 (ro)
RU (2) RU2630692C2 (ro)
SI (1) SI2778172T1 (ro)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016159092A1 (ja) * 2015-03-30 2016-10-06 Meiji Seikaファルマ株式会社 エピルビシンの製造方法およびその新規な製造中間体
CN104861014B (zh) * 2015-06-03 2017-09-29 道中道(菏泽)制药有限公司 一种盐酸表阿霉素结晶的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1155446B (it) 1982-12-23 1987-01-28 Erba Farmitalia Procedimento per la purificazione di glucosidi antraciclinonici mediante adsobimento selettivo su resine
CN1761457B (zh) * 2003-03-21 2010-05-12 帝斯曼知识产权资产管理有限公司 三水羟氨苄青霉素
WO2005004805A2 (en) * 2003-07-02 2005-01-20 Solux Corporation Thermally stable crystalline epirubicin hydrochloride and method of making the same
US20090099346A1 (en) * 2003-07-02 2009-04-16 Victor Matvienko Thermally stable crystalline epirubicin hydrochloride
GB0902009D0 (en) * 2009-02-09 2009-03-11 Innospec Ltd Improvements in fuels
ES2351494B1 (es) * 2009-06-30 2011-11-28 Consejo Superior De Investigaciones Cientificas (Csic) (85,7%) Material organo-inorganico microporoso cristalino basado en cationes alcalinoterreos, procedimiento de preparacion y usos
KR101125460B1 (ko) 2010-03-24 2012-03-28 동아제약주식회사 에피루비신 염산염의 신규한 결정형
CN102120750B (zh) * 2011-01-30 2013-04-03 山东新时代药业有限公司 一种盐酸表柔比星的纯化方法
DE102011103751A1 (de) * 2011-05-31 2012-12-06 Heraeus Precious Metals Gmbh & Co. Kg Kristallisierung von Epirubicinhydrochlorid

Also Published As

Publication number Publication date
CN104045672A (zh) 2014-09-17
HK1199264A1 (en) 2015-06-26
EP2778171A1 (en) 2014-09-17
EP2778172B1 (en) 2017-02-01
SI2778172T1 (sl) 2017-07-31
PT2778172T (pt) 2017-05-03
RU2014109682A (ru) 2015-09-20
RU2630692C2 (ru) 2017-09-12
KR101751099B1 (ko) 2017-06-26
RU2017117890A3 (ro) 2018-11-26
ES2623218T3 (es) 2017-07-10
KR20140113441A (ko) 2014-09-24
JP2014181235A (ja) 2014-09-29
PL2778172T3 (pl) 2017-08-31
DK2778172T3 (en) 2017-04-10
CN104045672B (zh) 2017-09-15
RU2017117890A (ru) 2018-11-26
JP5964339B2 (ja) 2016-08-03
US20190382432A1 (en) 2019-12-19
HUE034152T2 (en) 2018-01-29
US20140271874A1 (en) 2014-09-18
RS55850B1 (sr) 2017-08-31
RU2700683C2 (ru) 2019-09-19
EP2778172A1 (en) 2014-09-17

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