IN2014CN02581A - - Google Patents
Info
- Publication number
- IN2014CN02581A IN2014CN02581A IN2581CHN2014A IN2014CN02581A IN 2014CN02581 A IN2014CN02581 A IN 2014CN02581A IN 2581CHN2014 A IN2581CHN2014 A IN 2581CHN2014A IN 2014CN02581 A IN2014CN02581 A IN 2014CN02581A
- Authority
- IN
- India
- Prior art keywords
- inducing
- immune response
- compositions
- humoral
- humoral immune
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000028996 humoral immune response Effects 0.000 abstract 2
- 230000001939 inductive effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 101000831567 Homo sapiens Toll-like receptor 2 Proteins 0.000 abstract 1
- 102100024333 Toll-like receptor 2 Human genes 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000001668 ameliorated effect Effects 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000008348 humoral response Effects 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 239000002502 liposome Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/07—Bacillus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161544020P | 2011-10-06 | 2011-10-06 | |
PCT/CA2012/050705 WO2013049941A1 (en) | 2011-10-06 | 2012-10-05 | Liposome compositions comprising an adjuvant that activates or increases the activity of tlr2 and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014CN02581A true IN2014CN02581A (enrdf_load_stackoverflow) | 2015-08-07 |
Family
ID=48043153
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN2581CHN2014 IN2014CN02581A (enrdf_load_stackoverflow) | 2011-10-06 | 2012-10-05 |
Country Status (12)
Families Citing this family (42)
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US20100233270A1 (en) | 2009-01-08 | 2010-09-16 | Northwestern University | Delivery of Oligonucleotide-Functionalized Nanoparticles |
IN2014CN02581A (enrdf_load_stackoverflow) * | 2011-10-06 | 2015-08-07 | Immunovaccine Technologies Inc | |
CN111905099A (zh) | 2013-03-27 | 2020-11-10 | 免疫疫苗技术有限公司 | 用于改善存活蛋白疫苗在癌症治疗中的功效的方法 |
JP6659535B2 (ja) * | 2013-06-28 | 2020-03-04 | オークランド ユニサービシーズ リミティド | アミノ酸及びペプチド接合体及び接合方法 |
CN105579582A (zh) | 2013-07-25 | 2016-05-11 | 埃克西奎雷股份有限公司 | 用于预防和治疗用途的作为免疫刺激剂的基于球形核酸的构建体 |
JP6527516B2 (ja) | 2013-12-03 | 2019-06-05 | ノースウェスタン ユニバーシティ | リポソーム粒子、前述のものを作製する方法及びその使用 |
WO2015164565A1 (en) * | 2014-04-23 | 2015-10-29 | University Of Florida Research Foundation Incorporated | Lipoteichoic acid from lactobacilli as a potent immune stimulatory adjuvant for vaccine development |
WO2015187966A1 (en) * | 2014-06-04 | 2015-12-10 | Aurasense Therapeutics, Llc | Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications |
US11213593B2 (en) | 2014-11-21 | 2022-01-04 | Northwestern University | Sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates |
EP3237374A4 (en) | 2014-12-23 | 2018-04-25 | Margaret Anne Brimble | Amino acid and peptide conjugates and uses thereof |
CN107531736B (zh) | 2015-01-06 | 2022-04-15 | 免疫疫苗科技公司 | 脂质a模拟物、其制备方法和用途 |
AU2016219379B2 (en) * | 2015-02-10 | 2020-11-26 | Ohio State Innovation Foundation | Chlamydia-activated B cell platforms and methods thereof |
CN106606775A (zh) * | 2015-10-27 | 2017-05-03 | 格里菲斯大学 | 脂质体a群链球菌疫苗 |
EP3373961A4 (en) | 2015-11-10 | 2019-07-31 | Ohio State Innovation Foundation | METHODS AND COMPOSITIONS ASSOCIATED WITH ACCELERATED HUMORAL AFFINITY |
WO2017083963A1 (en) | 2015-11-18 | 2017-05-26 | Immunovaccine Technologies Inc. | Adjuvanting systems and water-free vaccine compositions comprising a polyi:c polynucleotide adjuvant and a lipid-based adjuvant |
CN105483076B (zh) * | 2015-12-23 | 2019-01-25 | 中国科学院生物物理研究所 | 一种脂肪体的制备方法及其应用 |
AU2017223267B2 (en) | 2016-02-26 | 2021-07-22 | Auckland Uniservices Limited | Amino acid and peptide conjugates and conjugation process |
US11260116B2 (en) | 2016-05-04 | 2022-03-01 | Immunovaccine Technologies Inc. | Vaccine compositions comprising an amphipathic compound, a neoantigen and a hydrophobic carrier, and methods of use thereof |
IL319503A (en) * | 2016-05-16 | 2025-05-01 | Access To Advanced Health Inst | PEGylated liposomes and methods of use |
AU2017294751B2 (en) * | 2016-07-13 | 2023-10-05 | Ohio State Innovation Foundation | Platforms and methods for optimizing host antigen presentation and host antitumor and antipathogen immunity |
WO2018039629A2 (en) | 2016-08-25 | 2018-03-01 | Northwestern University | Micellar spherical nucleic acids from thermoresponsive, traceless templates |
WO2018058230A1 (en) | 2016-09-27 | 2018-04-05 | Immunovaccine Technologies Inc. | Methods of using low dose volume b-cell epitope compositions for inducing an antibody immune response in human subjects |
CN110461351B (zh) * | 2017-03-31 | 2024-03-26 | 艾娜呼吸私人有限公司 | 用tlr2激动剂治疗呼吸道感染 |
WO2018209270A1 (en) | 2017-05-11 | 2018-11-15 | Northwestern University | Adoptive cell therapy using spherical nucleic acids (snas) |
AU2017423053A1 (en) * | 2017-07-10 | 2020-01-23 | Immunovaccine Technologies Inc. | Pharmaceutical compositions, methods for preparation using lipid vesicle particles of defined size, and uses thereof |
EP3652186A4 (en) | 2017-07-13 | 2021-03-31 | Northwestern University | GENERAL AND DIRECT PROCESS FOR PREPARING NANOPARTICLES WITH ORGANOMETALLIC STRUCTURE FUNCTIONALIZED BY OLIGONUCLEOTIDES |
KR102098097B1 (ko) * | 2017-08-16 | 2020-05-26 | 주식회사 차백신연구소 | 리포펩티드가 삽입된 리포좀을 유효성분으로 포함하는 백신 아쥬반트 및 이의 용도 |
WO2019119134A1 (en) * | 2017-12-19 | 2019-06-27 | The Governors Of The University Of Alberta | Clostridium perfringens surface glycans and uses thereof |
US12195557B2 (en) | 2017-12-21 | 2025-01-14 | Axelia Oncology Pty Ltd | Optimised compounds |
CN109991422A (zh) * | 2017-12-29 | 2019-07-09 | 复旦大学 | 基于特异抗血清的棕榈酰化修饰蛋白质的检测方法 |
JP2021518373A (ja) * | 2018-03-20 | 2021-08-02 | イミューノヴァクシーン テクノロジーズ インコーポレイテッドImmunovaccine Technologies Inc. | 活性剤及び免疫調節剤のリンパ節への標的化送達のための方法及び組成物 |
JP7713213B2 (ja) | 2018-04-10 | 2025-07-25 | エイシー イミューン ソシエテ アノニム | 抗-aベータ治療用ワクチン |
CA3106358A1 (en) * | 2018-07-12 | 2020-01-16 | The Regents Of The University Of Michigan | Compositions and methods for metal containing formulations capable of modulating immune response |
US20220047698A1 (en) * | 2018-10-26 | 2022-02-17 | Alberta Research Chemicals Inc. | Synthetic innate immune receptor ligands and uses thereof |
MX2021009790A (es) * | 2019-02-15 | 2022-01-18 | Cleveland Clinic Found | Adyuvantes y formulaciones para vacunas. |
US20220388950A1 (en) * | 2019-06-26 | 2022-12-08 | Axelia Oncology Pty Ltd | Novel molecules |
AU2020343725A1 (en) * | 2019-09-04 | 2022-03-24 | Axelia Oncology Pty Ltd | Cancer treatment |
JP2022546806A (ja) * | 2019-09-04 | 2022-11-09 | アクセリア オンコロジー ピーティーワイ リミテッド | 癌免疫療法 |
US12319711B2 (en) | 2019-09-20 | 2025-06-03 | Northwestern University | Spherical nucleic acids with tailored and active protein coronae |
US12378560B2 (en) | 2019-10-29 | 2025-08-05 | Northwestern University | Sequence multiplicity within spherical nucleic acids |
US20220280631A1 (en) * | 2021-03-07 | 2022-09-08 | Henry J. Smith | Viral pandemic vaccine |
CN113181353B (zh) * | 2021-04-09 | 2022-12-13 | 华中师范大学 | 一种抗病毒疫苗分子及其制备方法与应用 |
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- 2012-10-05 JP JP2014533747A patent/JP6240077B2/ja not_active Expired - Fee Related
- 2012-10-05 BR BR112014007927-7A patent/BR112014007927B1/pt not_active IP Right Cessation
- 2012-10-05 CA CA2850857A patent/CA2850857C/en active Active
- 2012-10-05 WO PCT/CA2012/050705 patent/WO2013049941A1/en active Application Filing
- 2012-10-05 ES ES12838879T patent/ES2855474T3/es active Active
- 2012-10-05 AU AU2012321022A patent/AU2012321022B2/en not_active Ceased
- 2012-10-05 CN CN202111215904.2A patent/CN113876945A/zh active Pending
- 2012-10-05 US US14/347,928 patent/US10105435B2/en active Active
- 2012-10-05 SG SG11201401177WA patent/SG11201401177WA/en unknown
- 2012-10-05 EP EP12838879.0A patent/EP2763698B1/en active Active
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2017
- 2017-07-14 JP JP2017138141A patent/JP6625587B2/ja not_active Expired - Fee Related
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- 2018-09-24 US US16/139,361 patent/US11077184B2/en active Active
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US20140234404A1 (en) | 2014-08-21 |
US20210308252A1 (en) | 2021-10-07 |
JP2018008964A (ja) | 2018-01-18 |
US11077184B2 (en) | 2021-08-03 |
ES2855474T3 (es) | 2021-09-23 |
US20190142928A1 (en) | 2019-05-16 |
US10105435B2 (en) | 2018-10-23 |
AU2012321022B2 (en) | 2017-03-23 |
AU2012321022A1 (en) | 2014-04-17 |
CA2850857A1 (en) | 2013-04-11 |
JP2014528955A (ja) | 2014-10-30 |
IL231888B (en) | 2018-02-28 |
SG11201401177WA (en) | 2014-04-28 |
WO2013049941A1 (en) | 2013-04-11 |
EP2763698B1 (en) | 2020-12-02 |
HK1201044A1 (en) | 2015-10-23 |
CN103998058A (zh) | 2014-08-20 |
CN103998058B (zh) | 2021-11-05 |
EP2763698A1 (en) | 2014-08-13 |
BR112014007927A2 (pt) | 2017-04-11 |
CN113876945A (zh) | 2022-01-04 |
CA2850857C (en) | 2022-07-26 |
BR112014007927B1 (pt) | 2021-04-13 |
EP2763698A4 (en) | 2015-08-05 |
IL231888A0 (en) | 2014-05-28 |
JP6625587B2 (ja) | 2019-12-25 |
JP6240077B2 (ja) | 2017-11-29 |
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