IN2014CN00953A - - Google Patents
Info
- Publication number
- IN2014CN00953A IN2014CN00953A IN953CHN2014A IN2014CN00953A IN 2014CN00953 A IN2014CN00953 A IN 2014CN00953A IN 953CHN2014 A IN953CHN2014 A IN 953CHN2014A IN 2014CN00953 A IN2014CN00953 A IN 2014CN00953A
- Authority
- IN
- India
- Prior art keywords
- influenza
- viruses
- binding molecules
- well
- group
- Prior art date
Links
- 241000712431 Influenza A virus Species 0.000 abstract 2
- 241000713196 Influenza B virus Species 0.000 abstract 2
- 101710154606 Hemagglutinin Proteins 0.000 abstract 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 abstract 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 abstract 1
- 101710176177 Protein A56 Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000000185 hemagglutinin Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1018—Orthomyxoviridae, e.g. influenza virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/11—Orthomyxoviridae, e.g. influenza virus
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161572417P | 2011-07-14 | 2011-07-14 | |
| EP11173953 | 2011-07-14 | ||
| PCT/EP2012/063637 WO2013007770A1 (en) | 2011-07-14 | 2012-07-12 | Human binding molecules capable of neutralizing influenza a viruses of phylogenetic group 1 and phylogenetic group 2 and influenza b viruses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN00953A true IN2014CN00953A (es) | 2015-04-10 |
Family
ID=47505543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN953CHN2014 IN2014CN00953A (es) | 2011-07-14 | 2012-07-12 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8961978B2 (es) |
| EP (1) | EP2731967B1 (es) |
| JP (1) | JP5683752B2 (es) |
| KR (1) | KR101941724B1 (es) |
| CN (1) | CN103906763B (es) |
| AU (1) | AU2012282504B2 (es) |
| BR (1) | BR112014000263B1 (es) |
| CA (1) | CA2838999C (es) |
| DK (1) | DK2731967T3 (es) |
| EA (1) | EA027054B1 (es) |
| ES (1) | ES2608321T3 (es) |
| HR (1) | HRP20161740T1 (es) |
| IL (1) | IL230222A (es) |
| IN (1) | IN2014CN00953A (es) |
| MX (1) | MX346206B (es) |
| MY (1) | MY166282A (es) |
| WO (1) | WO2013007770A1 (es) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY166282A (en) | 2011-07-14 | 2018-06-25 | Crucell Holland Bv | Human binding molecules capable of neutralizing influenza a viruses of phylogenetic group 1 and phylogenetic group 2 and influenza b viruses |
| IN2014CN04742A (es) | 2011-11-28 | 2015-09-18 | Crucell Holland Bv | |
| CA2861515A1 (en) | 2011-12-05 | 2013-06-13 | Trellis Bioscience, Llc | Antibodies useful in passive influenza immunization |
| US9969794B2 (en) | 2012-05-10 | 2018-05-15 | Visterra, Inc. | HA binding agents |
| CN105209071A (zh) | 2013-03-14 | 2015-12-30 | 抗非特公司 | 用于提高疗效的基于鼻内递送中和抗体的组合物和方法 |
| US9649375B2 (en) | 2013-03-14 | 2017-05-16 | The Administrators Of The Tulane Educational Fund | Immunogenic peptide conjugate and method for inducing an anti-influenza therapeutic antibody response therewith |
| KR20140118682A (ko) * | 2013-03-29 | 2014-10-08 | (주)셀트리온 | 2 이상의 인플루엔자 ａ 바이러스 중화 결합 분자를 포함하는 조성물 |
| MX369317B (es) | 2013-05-30 | 2019-11-05 | Janssen Vaccines & Prevention Bv | Vacunas contra el virus de la influenza y sus usos. |
| CN113667012A (zh) | 2013-10-02 | 2021-11-19 | 免疫医疗有限责任公司 | 中和抗甲型流感抗体及其用途 |
| RU2682049C2 (ru) * | 2014-01-27 | 2019-03-14 | Дженентек, Инк. | Лечение вируса гриппа а h7n9 |
| US10639370B2 (en) | 2014-02-04 | 2020-05-05 | Contrafect Corporation | Antibodies useful in passive influenza immunization, and compositions, combinations and methods for use thereof |
| RU2720282C1 (ru) * | 2014-02-04 | 2020-04-28 | Контрафект Корпорейшн | Антитела, подходящие для пассивной иммунизации против гриппа, и их композиции, комбинации и способы применения |
| CN105992772A (zh) | 2014-02-10 | 2016-10-05 | Igm生命科学股份有限公司 | IgA多特异性结合分子 |
| BR112016022113A2 (pt) | 2014-03-27 | 2017-10-31 | Genentech Inc | anticorpos anti-hemaglutinina do vírus influenza b e métodos de uso |
| KR101628331B1 (ko) * | 2014-03-28 | 2016-06-08 | 주식회사 녹십자엠에스 | 인플루엔자 a 바이러스 특이적 단클론 항체 및 이를 이용한 인플루엔자 감염 치료 및 진단 방법 |
| WO2016005482A1 (en) | 2014-07-10 | 2016-01-14 | Crucell Holland B.V. | Influenza virus vaccines and uses thereof |
| EA038400B1 (ru) | 2014-07-10 | 2021-08-23 | Янссен Вэксинс Энд Превеншн Б.В. | Полипептид стеблевого домена гемагглютинина вируса гриппа и его применение |
| JP6837434B2 (ja) | 2014-07-15 | 2021-03-03 | メディミューン，エルエルシー | 抗ｂ型インフルエンザ抗体の中和及びその使用 |
| TWI702229B (zh) | 2014-12-19 | 2020-08-21 | 美商再生元醫藥公司 | 流行性感冒病毒血球凝集素之人類抗體 |
| US10174127B2 (en) | 2015-02-05 | 2019-01-08 | Janssen Vaccines & Prevention B.V. | Human neutralizing antibodies binding to influenza neuraminidase |
| CA2975655C (en) * | 2015-02-05 | 2023-09-19 | Janssen Vaccines & Prevention B.V. | Binding molecules directed against influenza hemagglutinin and uses thereof |
| KR20170133507A (ko) | 2015-04-08 | 2017-12-05 | 다나-파버 캔서 인스티튜트 인크. | 인간화된 인플루엔자 모노클로날 항체 및 그의 사용 방법 |
| WO2016180826A1 (en) | 2015-05-11 | 2016-11-17 | Janssen Vaccines & Prevention B.V. | Influenza virus neutralizing peptidomimetic compounds |
| WO2016200543A2 (en) | 2015-05-13 | 2016-12-15 | The Trustees Of The University Of Pennsylvania | Aav-mediated expression of anti-inluenza antibodies and methods of use thereof |
| PT3303384T (pt) | 2015-06-01 | 2021-10-14 | Medimmune Llc | Moléculas de ligação neutralizantes anti-influenza e suas utilizações |
| EP3374390A1 (en) | 2015-11-13 | 2018-09-19 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
| CN108697789A (zh) | 2016-01-13 | 2018-10-23 | 免疫医疗有限责任公司 | 治疗甲型流感的方法 |
| US10703803B2 (en) | 2016-03-01 | 2020-07-07 | Janssen Vaccines & Prevention B.V. | Human neutralizing antibodies binding to influenza B neuraminidase |
| WO2017192589A1 (en) * | 2016-05-02 | 2017-11-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to influenza ha and their use and identification |
| WO2018038096A1 (ja) * | 2016-08-23 | 2018-03-01 | 国立大学法人東京大学 | モノクローナル抗体又はその抗原結合フラグメント及びその使用 |
| KR20190071714A (ko) | 2016-10-27 | 2019-06-24 | 얀센 백신스 앤드 프리벤션 비.브이. | 인플루엔자 바이러스 중화 화합물 |
| WO2018138681A1 (en) * | 2017-01-27 | 2018-08-02 | National Research Council Of Canada | Hemagglutinin-specific antibodies and uses thereof |
| EP3577107A1 (en) | 2017-02-02 | 2019-12-11 | Janssen Vaccines & Prevention B.V. | Piperazine derivatives for influenza virus inhibition |
| WO2018141854A1 (en) | 2017-02-02 | 2018-08-09 | Janssen Vaccines & Prevention B.V. | Piperazine derivatives for influenza virus inhibition |
| JOP20190200A1 (ar) | 2017-02-28 | 2019-08-27 | Univ Pennsylvania | تركيبات نافعة في معالجة ضمور العضل النخاعي |
| WO2018160573A1 (en) | 2017-02-28 | 2018-09-07 | The Trustees Of The University Of Pennsylvania | Influenza vaccines based on aav vectors |
| SG10201912976WA (en) | 2017-02-28 | 2020-02-27 | Univ Pennsylvania | Adeno-associated virus (aav) clade f vector and uses therefor |
| DK3743106T3 (da) | 2018-01-23 | 2022-09-05 | Janssen Vaccines & Prevention Bv | Influenzavirusvacciner og anvendelser deraf |
| MA51681A (fr) | 2018-01-26 | 2021-05-05 | Regeneron Pharma | Anticorps humains contre l'hémagglutinine de la grippe |
| US11230593B2 (en) | 2019-03-25 | 2022-01-25 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
| MX2022002766A (es) * | 2019-09-05 | 2022-04-06 | Janssen Vaccines & Prevention Bv | Vacunas contra el virus de la gripe y usos de las mismas. |
| WO2021173965A1 (en) | 2020-02-28 | 2021-09-02 | Massachusetts Institute Of Technology | Identification of variable influenza residues and uses thereof |
| WO2021201677A1 (en) | 2020-04-01 | 2021-10-07 | Kiadis Pharma Intellectual Property B.V. | Compositions and methods targeting influenza |
| US11175293B1 (en) | 2021-01-04 | 2021-11-16 | University Of Utah Research Foundation | Rapid assay for detection of SARS-CoV-2 antibodies |
| WO2022166767A1 (zh) | 2021-02-04 | 2022-08-11 | 四川海思科制药有限公司 | Ha抑制剂化合物的盐及晶型 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
| NL9101953A (nl) | 1991-11-21 | 1993-06-16 | Seed Capital Investments | Testinrichting omvattende een plaat met een veelvoud van putjes met een bijbehorende doseerinrichting, alsmede een kit die deze inrichtingen omvat en toepassing van de inrichtingen. |
| US6265150B1 (en) | 1995-06-07 | 2001-07-24 | Becton Dickinson & Company | Phage antibodies |
| ATE230850T1 (de) | 1996-10-08 | 2003-01-15 | Bisys B V U | Verfahren und mittel zur auswahl von peptiden und proteinen mit spezifischer affinität zu einem zielmolekül |
| CN100457914C (zh) | 1999-04-15 | 2009-02-04 | 荷兰克鲁塞尔公司 | 用编码腺病毒e1蛋白的序列在人体细胞中生产重组蛋白 |
| CA2449071C (en) | 2001-06-15 | 2008-12-16 | Crucell Holland B.V. | Chimaeric phages |
| AU2007293662B2 (en) * | 2006-09-07 | 2012-10-04 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza virus H5N1 and uses thereof |
| FR2921928B1 (fr) * | 2007-10-08 | 2011-03-04 | Sanofi Pasteur | Anticorps monoclonaux specifiques de l'hemagglutinine du virus grippal |
| CA2733218A1 (en) | 2008-07-25 | 2010-01-28 | Institute For Research In Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
| EP2168987A1 (en) * | 2008-09-22 | 2010-03-31 | Mucosis B.V. | Multifunctional linker protein containing an antibody against hemagglutinin, a conserved influenza antigen and an immunostimulating carrier binding domain |
| CN102448986B (zh) | 2009-05-11 | 2015-11-25 | 克鲁塞尔荷兰公司 | 能中和流感病毒h3n2的人结合分子及其应用 |
| MY166282A (en) | 2011-07-14 | 2018-06-25 | Crucell Holland Bv | Human binding molecules capable of neutralizing influenza a viruses of phylogenetic group 1 and phylogenetic group 2 and influenza b viruses |
-
2012
- 2012-07-12 MY MYPI2014700068A patent/MY166282A/en unknown
- 2012-07-12 EP EP12735516.2A patent/EP2731967B1/en active Active
- 2012-07-12 IN IN953CHN2014 patent/IN2014CN00953A/en unknown
- 2012-07-12 CA CA2838999A patent/CA2838999C/en active Active
- 2012-07-12 EA EA201490288A patent/EA027054B1/ru not_active IP Right Cessation
- 2012-07-12 BR BR112014000263-0A patent/BR112014000263B1/pt active IP Right Grant
- 2012-07-12 KR KR1020137035132A patent/KR101941724B1/ko active IP Right Grant
- 2012-07-12 DK DK12735516.2T patent/DK2731967T3/en active
- 2012-07-12 CN CN201280034558.0A patent/CN103906763B/zh active Active
- 2012-07-12 ES ES12735516.2T patent/ES2608321T3/es active Active
- 2012-07-12 US US14/126,404 patent/US8961978B2/en active Active
- 2012-07-12 MX MX2014000373A patent/MX346206B/es active IP Right Grant
- 2012-07-12 JP JP2014519551A patent/JP5683752B2/ja active Active
- 2012-07-12 AU AU2012282504A patent/AU2012282504B2/en active Active
- 2012-07-12 WO PCT/EP2012/063637 patent/WO2013007770A1/en active Application Filing
-
2013
- 2013-12-29 IL IL230222A patent/IL230222A/en active IP Right Grant
-
2015
- 2015-01-14 US US14/597,016 patent/US9593159B2/en active Active
-
2016
- 2016-12-19 HR HRP20161740TT patent/HRP20161740T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA201490288A1 (ru) | 2014-05-30 |
| JP5683752B2 (ja) | 2015-03-11 |
| MX2014000373A (es) | 2014-03-31 |
| MY166282A (en) | 2018-06-25 |
| NZ618530A (en) | 2016-05-27 |
| US9593159B2 (en) | 2017-03-14 |
| BR112014000263B1 (pt) | 2022-01-18 |
| KR101941724B1 (ko) | 2019-01-23 |
| CA2838999C (en) | 2021-02-16 |
| BR112014000263A2 (pt) | 2017-02-14 |
| KR20140095017A (ko) | 2014-07-31 |
| HRP20161740T1 (hr) | 2017-02-10 |
| US20140120113A1 (en) | 2014-05-01 |
| EA027054B1 (ru) | 2017-06-30 |
| US8961978B2 (en) | 2015-02-24 |
| IL230222A (en) | 2017-09-28 |
| EP2731967A1 (en) | 2014-05-21 |
| EP2731967B1 (en) | 2016-10-12 |
| CN103906763B (zh) | 2016-10-12 |
| CN103906763A (zh) | 2014-07-02 |
| AU2012282504A1 (en) | 2014-02-06 |
| WO2013007770A1 (en) | 2013-01-17 |
| ES2608321T3 (es) | 2017-04-07 |
| JP2014527403A (ja) | 2014-10-16 |
| AU2012282504B2 (en) | 2017-07-20 |
| US20150274811A1 (en) | 2015-10-01 |
| MX346206B (es) | 2017-03-09 |
| CA2838999A1 (en) | 2013-01-17 |
| DK2731967T3 (en) | 2017-01-16 |
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