IN2012DN03391A - - Google Patents
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- Publication number
- IN2012DN03391A IN2012DN03391A IN3391DEN2012A IN2012DN03391A IN 2012DN03391 A IN2012DN03391 A IN 2012DN03391A IN 3391DEN2012 A IN3391DEN2012 A IN 3391DEN2012A IN 2012DN03391 A IN2012DN03391 A IN 2012DN03391A
- Authority
- IN
- India
- Prior art keywords
- compound
- methyl
- processes
- relates
- luoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26226309P | 2009-11-18 | 2009-11-18 | |
| PCT/SE2010/051269 WO2011062550A1 (fr) | 2009-11-18 | 2010-11-17 | Composés de benzoimidazole et utilisations de ceux-ci |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN03391A true IN2012DN03391A (fr) | 2015-10-23 |
Family
ID=44059844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3391DEN2012 IN2012DN03391A (fr) | 2009-11-18 | 2010-11-17 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8530467B2 (fr) |
| EP (1) | EP2501697B1 (fr) |
| JP (1) | JP5657018B2 (fr) |
| KR (1) | KR20120113709A (fr) |
| CN (1) | CN102741245B (fr) |
| AR (1) | AR079050A1 (fr) |
| AU (1) | AU2010322478B2 (fr) |
| BR (1) | BR112012011518B8 (fr) |
| CA (1) | CA2777746C (fr) |
| ES (1) | ES2442797T3 (fr) |
| IN (1) | IN2012DN03391A (fr) |
| MX (1) | MX2012005329A (fr) |
| RU (1) | RU2542582C2 (fr) |
| TW (1) | TW201121957A (fr) |
| UY (1) | UY33037A (fr) |
| WO (1) | WO2011062550A1 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012158117A1 (fr) * | 2011-05-17 | 2012-11-22 | Astrazeneca Ab | Traitements combinés pour le traitement de la douleur |
| EP2951177B1 (fr) * | 2013-01-31 | 2018-04-04 | Neomed Institute | Composés imidazopyridine et leurs utilisations |
| WO2015093586A1 (fr) * | 2013-12-20 | 2015-06-25 | 塩野義製薬株式会社 | Procédés pour produire respectivement, un composé optiquement actif présentant une activité agoniste sur les récepteurs de la thrombopoïétine et un intermédiaire dudit composé |
| EP3164132A4 (fr) * | 2014-07-03 | 2018-02-21 | Afferent Pharmaceuticals Inc. | Méthodes et compositions pour le traitement de maladies et d'affections |
| US10111883B1 (en) * | 2017-09-18 | 2018-10-30 | Bellus Health Cough Inc. | Selective P2X3 modulators |
| CN108904507A (zh) * | 2018-02-11 | 2018-11-30 | 赖英杰 | P2x3受体调节剂苯并咪唑化合物在制备抗呼吸疾病药物中的应用 |
| JP2022515879A (ja) * | 2018-12-29 | 2022-02-22 | 武漢朗来科技発展有限公司 | 複素環式化合物、中間体、その製造方法及び応用 本願は、出願日が２０１８年１２月２９日の中国特許出願ｃｎ ２０１８１１６４２３１９、出願日が２０１９年０５月２４日の中国特許出願ｃｎ２０１９１０４４０２１４．３及び出願日が２０１９年１０月２４日の中国特許出願ｃｎ２０１９１１０１６１５８．７に基づいて優先権を主張する。また、上記中国特許出願の全文は本願に援用される。 |
| CN115835867A (zh) * | 2020-08-13 | 2023-03-21 | 上海拓界生物医药科技有限公司 | 苯并咪唑类衍生物、其制备方法及医药用途 |
| WO2022117062A1 (fr) * | 2020-12-04 | 2022-06-09 | 上海拓界生物医药科技有限公司 | Composés contenant un noyau tricyclique condensé et leur utilisation pharmaceutique |
| CN114478508A (zh) * | 2021-12-31 | 2022-05-13 | 淮北师范大学 | 一种苯并咪唑化合物的结晶形式 |
| WO2023151660A1 (fr) * | 2022-02-11 | 2023-08-17 | 江苏恒瑞医药股份有限公司 | Forme cristalline d'un antagoniste du récepteur p2x3 et son procédé de préparation |
| WO2023151658A1 (fr) * | 2022-02-11 | 2023-08-17 | 江苏恒瑞医药股份有限公司 | Sel pharmaceutiquement acceptable d'un antagoniste du récepteur p2x3 et son procédé de préparation |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6026A (en) * | 1849-01-09 | Cast-iron car-wheel | ||
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| BR9707495A (pt) | 1996-02-13 | 1999-07-27 | Zeneca Ltd | Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente |
| KR100489174B1 (ko) | 1996-03-05 | 2005-09-30 | 제네카-파마 소시에떼아노님 | 4-아닐리노퀴나졸린유도체 |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| ATE482946T1 (de) | 1999-02-10 | 2010-10-15 | Astrazeneca Ab | Chinazolinderivate als angiogenesehemmer und zwischenprodukte dafür |
| DE60130865T2 (de) * | 2000-01-17 | 2008-07-17 | Teijin Pharma Ltd. | Benzimidazol-derivate als menschliche chymase - inhibitoren |
| IL152682A0 (en) | 2000-05-31 | 2003-06-24 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| UA73993C2 (uk) | 2000-06-06 | 2005-10-17 | Астразенека Аб | Хіназолінові похідні для лікування пухлин та фармацевтична композиція |
| MXPA02012905A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como agentes de dano vascular.. |
| HUP0301742A3 (en) | 2000-07-07 | 2005-08-29 | Angiogene Pharm Ltd | Colchinol derivatives as angiogenesis inhibitors, process for producing them, pharmaceutical compositions containing them and their use |
| RU2374234C2 (ru) * | 2004-09-24 | 2009-11-27 | Астразенека Аб | Бензимидазольные производные, содержащие их композиции, их получение и применение |
| KR20090127902A (ko) * | 2007-03-02 | 2009-12-14 | 쉐링 코포레이션 | 벤즈이미다졸 유도체 및 이의 사용방법 |
| US20090099195A1 (en) | 2007-05-08 | 2009-04-16 | Astrazeneca Ab | Therapeutic Compounds 570 |
| AU2008319308B2 (en) * | 2007-10-31 | 2013-01-31 | Merck Sharp & Dohme Corp. | P2X3, receptor antagonists for treatment of pain |
-
2010
- 2010-11-17 AR ARP100104240A patent/AR079050A1/es unknown
- 2010-11-17 MX MX2012005329A patent/MX2012005329A/es active IP Right Grant
- 2010-11-17 IN IN3391DEN2012 patent/IN2012DN03391A/en unknown
- 2010-11-17 KR KR1020127012726A patent/KR20120113709A/ko not_active Application Discontinuation
- 2010-11-17 TW TW099139607A patent/TW201121957A/zh unknown
- 2010-11-17 BR BR112012011518A patent/BR112012011518B8/pt active IP Right Grant
- 2010-11-17 JP JP2012539853A patent/JP5657018B2/ja active Active
- 2010-11-17 ES ES10831876.7T patent/ES2442797T3/es active Active
- 2010-11-17 AU AU2010322478A patent/AU2010322478B2/en active Active
- 2010-11-17 WO PCT/SE2010/051269 patent/WO2011062550A1/fr active Application Filing
- 2010-11-17 CA CA2777746A patent/CA2777746C/fr active Active
- 2010-11-17 CN CN201080061596.6A patent/CN102741245B/zh active Active
- 2010-11-17 EP EP10831876.7A patent/EP2501697B1/fr active Active
- 2010-11-17 RU RU2012124268/04A patent/RU2542582C2/ru active
- 2010-11-18 UY UY0001033037A patent/UY33037A/es not_active Application Discontinuation
-
2012
- 2012-05-16 US US13/472,825 patent/US8530467B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2442797T3 (es) | 2014-02-13 |
| JP5657018B2 (ja) | 2015-01-21 |
| WO2011062550A1 (fr) | 2011-05-26 |
| US20120289504A1 (en) | 2012-11-15 |
| BR112012011518B1 (pt) | 2020-03-10 |
| KR20120113709A (ko) | 2012-10-15 |
| CA2777746C (fr) | 2019-05-14 |
| CN102741245B (zh) | 2014-11-05 |
| EP2501697A1 (fr) | 2012-09-26 |
| AR079050A1 (es) | 2011-12-21 |
| EP2501697B1 (fr) | 2013-10-23 |
| RU2012124268A (ru) | 2013-12-27 |
| CA2777746A1 (fr) | 2011-05-26 |
| RU2542582C2 (ru) | 2015-02-20 |
| AU2010322478A1 (en) | 2012-05-31 |
| TW201121957A (en) | 2011-07-01 |
| BR112012011518A2 (pt) | 2016-06-28 |
| JP2013511517A (ja) | 2013-04-04 |
| US8530467B2 (en) | 2013-09-10 |
| MX2012005329A (es) | 2012-05-29 |
| AU2010322478B2 (en) | 2013-11-14 |
| CN102741245A (zh) | 2012-10-17 |
| UY33037A (es) | 2011-06-30 |
| BR112012011518B8 (pt) | 2023-01-10 |
| EP2501697A4 (fr) | 2013-04-24 |
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