IN2012DN00696A - - Google Patents
Download PDFInfo
- Publication number
- IN2012DN00696A IN2012DN00696A IN696DEN2012A IN2012DN00696A IN 2012DN00696 A IN2012DN00696 A IN 2012DN00696A IN 696DEN2012 A IN696DEN2012 A IN 696DEN2012A IN 2012DN00696 A IN2012DN00696 A IN 2012DN00696A
- Authority
- IN
- India
- Prior art keywords
- iodophenylamino
- dihydroxypropyl
- cyclopropane
- sulfonamide
- difluoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/38—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
- C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
- C07C29/80—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment by distillation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22850909P | 2009-07-24 | 2009-07-24 | |
| US22850109P | 2009-07-24 | 2009-07-24 | |
| PCT/EP2010/004222 WO2011009541A1 (en) | 2009-07-24 | 2010-07-10 | Preparation of (r)- and (s)-n-(3, 4-difluoro-2-(2-fluoro-4-iodophenylamino)--6-methoxyphenyl) -1- (2, 3-dihydroxypropyl)cyclopropane-1-sulfonamide and protected derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN00696A true IN2012DN00696A (es) | 2015-06-19 |
Family
ID=42830488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN696DEN2012 IN2012DN00696A (es) | 2009-07-24 | 2010-07-10 |
Country Status (32)
| Country | Link |
|---|---|
| US (3) | US8513443B2 (es) |
| EP (1) | EP2462111B1 (es) |
| JP (1) | JP5776115B2 (es) |
| KR (1) | KR101763437B1 (es) |
| CN (2) | CN103848808B (es) |
| AR (1) | AR079183A1 (es) |
| AU (1) | AU2010275780B2 (es) |
| BR (1) | BR112012001592A2 (es) |
| CA (2) | CA2768788C (es) |
| CL (1) | CL2012000192A1 (es) |
| CO (1) | CO6491075A2 (es) |
| CR (1) | CR20120044A (es) |
| CU (1) | CU24113B1 (es) |
| DO (1) | DOP2012000017A (es) |
| EA (1) | EA023623B1 (es) |
| EC (1) | ECSP12011621A (es) |
| GT (1) | GT201200017A (es) |
| HK (2) | HK1171218A1 (es) |
| HN (1) | HN2012000142A (es) |
| IL (1) | IL217312A (es) |
| IN (1) | IN2012DN00696A (es) |
| MA (1) | MA33452B1 (es) |
| MX (2) | MX2012001063A (es) |
| MY (1) | MY160421A (es) |
| NZ (1) | NZ597738A (es) |
| PE (1) | PE20120573A1 (es) |
| PH (1) | PH12014500158A1 (es) |
| SG (1) | SG177535A1 (es) |
| TN (1) | TN2012000027A1 (es) |
| TW (1) | TWI524890B (es) |
| UY (1) | UY32800A (es) |
| WO (1) | WO2011009541A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI524890B (zh) * | 2009-07-24 | 2016-03-11 | 亞德生化公司 | （ｒ）－ｎ－（３，４－二氟－２－（２－氟－４－碘苯胺基）－６－甲氧基苯基）－１－（２，３－二羥丙基）環丙烷－１－磺醯胺及（ｓ）－ｎ－（３，４－二氟－２－（２－氟－４－碘苯胺基）－６－甲氧基苯基）－１－（２，３－二羥丙基）環丙烷－１－磺醯胺之製備 |
| PE20140580A1 (es) | 2011-05-27 | 2014-06-01 | Bayer Ip Gmbh | Sintesis quiral de n-{3,4-difluoro-2-[(2-fluoro-4-yodofenil)amino]-6-metoxifenil}-1-[2,3-dihidroxi-propil]ciclopropanosulfonamidas |
| EP2796455A4 (en) * | 2011-12-19 | 2015-08-19 | Sumitomo Chemical Co | PROCESS FOR PRODUCING SULFONATE |
| EP2848246A1 (en) | 2013-09-13 | 2015-03-18 | Bayer Pharma Aktiengesellschaft | Pharmaceutical compositions containing refametinib |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8101799B2 (en) * | 2005-07-21 | 2012-01-24 | Ardea Biosciences | Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK |
| CN101495118B (zh) * | 2005-07-21 | 2012-09-05 | 阿迪亚生命科学公司 | Mek的n-(芳基氨基)磺酰胺抑制剂 |
| US7842836B2 (en) | 2006-04-11 | 2010-11-30 | Ardea Biosciences | N-aryl-N'alkyl sulfamides as MEK inhibitors |
| CA2649122C (en) | 2006-04-18 | 2015-06-30 | Ardea Biosciences, Inc. | Pyridone sulfonamides and pyridone sulfamides as mek inhibitors |
| EP2175885B1 (en) * | 2007-07-30 | 2016-10-12 | Ardea Biosciences, Inc. | Combinations of mek inhibitors and raf kinase inhibitors and uses thereof |
| EP2291350A4 (en) * | 2008-04-14 | 2012-09-19 | Ardea Biosciences Inc | COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE AND USE |
| TWI524890B (zh) * | 2009-07-24 | 2016-03-11 | 亞德生化公司 | （ｒ）－ｎ－（３，４－二氟－２－（２－氟－４－碘苯胺基）－６－甲氧基苯基）－１－（２，３－二羥丙基）環丙烷－１－磺醯胺及（ｓ）－ｎ－（３，４－二氟－２－（２－氟－４－碘苯胺基）－６－甲氧基苯基）－１－（２，３－二羥丙基）環丙烷－１－磺醯胺之製備 |
-
2010
- 2010-07-09 TW TW099122740A patent/TWI524890B/zh not_active IP Right Cessation
- 2010-07-10 AU AU2010275780A patent/AU2010275780B2/en not_active Ceased
- 2010-07-10 EP EP10734043.2A patent/EP2462111B1/en active Active
- 2010-07-10 CN CN201310670649.XA patent/CN103848808B/zh not_active Expired - Fee Related
- 2010-07-10 EA EA201200175A patent/EA023623B1/ru not_active IP Right Cessation
- 2010-07-10 SG SG2012000964A patent/SG177535A1/en unknown
- 2010-07-10 NZ NZ597738A patent/NZ597738A/en not_active IP Right Cessation
- 2010-07-10 CN CN201080031572.6A patent/CN102471246B/zh not_active Expired - Fee Related
- 2010-07-10 IN IN696DEN2012 patent/IN2012DN00696A/en unknown
- 2010-07-10 PE PE2012000092A patent/PE20120573A1/es not_active Application Discontinuation
- 2010-07-10 BR BR112012001592A patent/BR112012001592A2/pt not_active Application Discontinuation
- 2010-07-10 JP JP2012520927A patent/JP5776115B2/ja not_active Expired - Fee Related
- 2010-07-10 US US13/386,519 patent/US8513443B2/en not_active Expired - Fee Related
- 2010-07-10 CA CA2768788A patent/CA2768788C/en not_active Expired - Fee Related
- 2010-07-10 KR KR1020127001737A patent/KR101763437B1/ko active IP Right Grant
- 2010-07-10 MY MYPI2012000099A patent/MY160421A/en unknown
- 2010-07-10 WO PCT/EP2010/004222 patent/WO2011009541A1/en active Application Filing
- 2010-07-10 CA CA2990097A patent/CA2990097A1/en not_active Abandoned
- 2010-07-10 CU CUP2012000014A patent/CU24113B1/es active IP Right Grant
- 2010-07-10 MA MA34562A patent/MA33452B1/fr unknown
- 2010-07-10 MX MX2012001063A patent/MX2012001063A/es active IP Right Grant
- 2010-07-22 UY UY0001032800A patent/UY32800A/es not_active Application Discontinuation
- 2010-07-23 AR ARP100102678A patent/AR079183A1/es unknown
-
2012
- 2012-01-01 IL IL217312A patent/IL217312A/en not_active IP Right Cessation
- 2012-01-19 TN TNP2012000027A patent/TN2012000027A1/en unknown
- 2012-01-23 CR CR20120044A patent/CR20120044A/es unknown
- 2012-01-24 GT GT201200017A patent/GT201200017A/es unknown
- 2012-01-24 HN HN2012000142A patent/HN2012000142A/es unknown
- 2012-01-24 EC EC2012011621A patent/ECSP12011621A/es unknown
- 2012-01-24 CO CO12010431A patent/CO6491075A2/es active IP Right Grant
- 2012-01-24 MX MX2014000732A patent/MX344965B/es unknown
- 2012-01-24 DO DO2012000017A patent/DOP2012000017A/es unknown
- 2012-01-24 CL CL2012000192A patent/CL2012000192A1/es unknown
- 2012-11-23 HK HK12112020.5A patent/HK1171218A1/xx not_active IP Right Cessation
-
2013
- 2013-04-23 US US13/868,621 patent/US8884058B2/en not_active Expired - Fee Related
-
2014
- 2014-01-16 PH PH12014500158A patent/PH12014500158A1/en unknown
- 2014-08-25 US US14/467,424 patent/US9296686B2/en not_active Expired - Fee Related
- 2014-11-24 HK HK14111856A patent/HK1198364A1/zh not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12017502300A1 (en) | Pesticidal compositions and processes related thereto | |
| WO2011061330A3 (de) | Verwendung physiologischer kühlwirkstoffe und mittel enthaltend solche wirkstoffe | |
| MX2013009175A (es) | Composiciones que comprenden acido peroxi alfa-cetocarboxilico y metodos para producirlas y usarlas. | |
| MX341825B (es) | Compuestos de heteroarilo y usos de los mismos. | |
| IN2012DN06629A (es) | ||
| WO2011106322A3 (en) | Biomarkers for acute ischemic stroke | |
| MX2011014019A (es) | Derivados de diazahomoadamantano y sus metodos de uso. | |
| EP2606139A4 (en) | BIOCATALYSTS AND METHODS FOR SYNTHESIZING (1R, 2R) -2- (3,4-DIMETHOXYPHENYL ETHYL) CYCLOHEXANAMINE | |
| WO2010118291A3 (en) | Biphenyl-3-carboxylic acid modulators of beta-3-adrenoreceptor | |
| IN2012DN00696A (es) | ||
| MX2012011382A (es) | Nuevo polimero. | |
| EP2576575A4 (en) | PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, THEIR METHODS OF MANUFACTURE AND USES THEREOF | |
| WO2011054804A3 (en) | Skin care compositions comprising phenoxyalkyl amines | |
| UA106762C2 (uk) | Спосіб одержання (r)- та (s)-n-(3,4-дифтор-2-(2-фтор-4-йодфеніламіно)-6-метоксифеніл)-1-(2,3-дигідроксипропіл)циклопропан-1-сульфанаміду та його захищених похідних | |
| SG178929A1 (en) | Use of cathepsin h | |
| WO2012027274A3 (en) | Compositions and methods for imaging | |
| AU2017202012A1 (en) | Preparation and use of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo(3.1.0)hexane in the treatment of conditions affected by monoamine neurotransmitters | |
| UA106192C2 (en) | N-(1,1-dioxotetrahydrothiophen-3-yl)bicyclo[2.2.1]hept-5-ene-endo,endo-2,3- dicarboximide and n-(1,1-dioxotetrahydrothiophen-3-yl)-exo-5,6-epoxybicyclo-[2.2.1]heptane-endo,endo-2,3-dicarboximide exhibiting analgetic and anticonvulsant action | |
| UA91166C2 (en) | use of ethyl ether N-[(2-oxoindolylinylydene-3)-2-oxyacetyl]-aminoacetic acid of the general formula as nootropic and anxyolytic agent | |
| UA35660U (en) | Use of antihomotoxic preparations as cytoprotectors | |
| UA48043U (ru) | Применение перфторана в качестве эхоконтрастного препарата при проведении интервенционных эндоваскулярных вмешательств | |
| UA59343U (ru) | Применение теобона-дитиомикоцида (n -(1,1-диоксотиолан-3-ил)-дитиокарбамата калия) как средства для лечения инфекционных поражений кожи | |
| UA52529U (ru) | Применение уретроскопа комбинированного (модель 513) как троакарной системы для эпицистостомии | |
| UA60476U (ru) | Применение (1,1-диоксотиолан-3-ил)дитиокарбамата калия в качестве антимикробного средства | |
| UA96059C2 (ru) | Применение липина как средства фригопротекторного действия |