IL98988A - Enzymatic preparation of basic fibroblast growth factor - Google Patents

Enzymatic preparation of basic fibroblast growth factor

Info

Publication number
IL98988A
IL98988A IL9898891A IL9898891A IL98988A IL 98988 A IL98988 A IL 98988A IL 9898891 A IL9898891 A IL 9898891A IL 9898891 A IL9898891 A IL 9898891A IL 98988 A IL98988 A IL 98988A
Authority
IL
Israel
Prior art keywords
bfgf
growth factor
thr
fibroblast growth
adduct
Prior art date
Application number
IL9898891A
Other languages
English (en)
Other versions
IL98988A0 (en
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of IL98988A0 publication Critical patent/IL98988A0/xx
Publication of IL98988A publication Critical patent/IL98988A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
IL9898891A 1990-08-02 1991-07-29 Enzymatic preparation of basic fibroblast growth factor IL98988A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909017008A GB9017008D0 (en) 1990-08-02 1990-08-02 Process for the enzymatic preparation of basic fibroblast growth factor

Publications (2)

Publication Number Publication Date
IL98988A0 IL98988A0 (en) 1992-07-15
IL98988A true IL98988A (en) 1997-02-18

Family

ID=10680087

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9898891A IL98988A (en) 1990-08-02 1991-07-29 Enzymatic preparation of basic fibroblast growth factor

Country Status (27)

Country Link
US (1) US5348863A (cs)
EP (1) EP0495049B1 (cs)
JP (1) JPH05501655A (cs)
KR (1) KR100191697B1 (cs)
CN (1) CN1033810C (cs)
AT (1) ATE152122T1 (cs)
AU (1) AU643822B2 (cs)
CA (1) CA2066174A1 (cs)
CZ (1) CZ286237B6 (cs)
DE (1) DE69125810T2 (cs)
DK (1) DK0495049T3 (cs)
ES (1) ES2103822T3 (cs)
FI (1) FI921428L (cs)
GB (1) GB9017008D0 (cs)
GR (1) GR3024111T3 (cs)
HU (1) HU212671B (cs)
IE (1) IE912729A1 (cs)
IL (1) IL98988A (cs)
MY (1) MY107334A (cs)
NO (1) NO301480B1 (cs)
NZ (1) NZ239204A (cs)
PH (1) PH31240A (cs)
PT (1) PT98544B (cs)
RU (1) RU2093519C1 (cs)
WO (1) WO1992002539A1 (cs)
YU (1) YU48309B (cs)
ZA (1) ZA916026B (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015753A1 (en) * 1992-02-14 1993-08-19 Kaken Pharmaceutical Co., Ltd. Remedy for airway diseases
CA2188395A1 (en) * 1994-04-21 1995-11-02 Hans Jakob Hem Flodgaard Heparin-binding protein for the treatment of sepsis and processes for its preparation
US5939390A (en) * 1995-03-09 1999-08-17 Novo Nordisk A/S Pharmaceutical composition
US6274712B1 (en) 1997-12-23 2001-08-14 3-Dimensional Pharmaceuticals, Inc. Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamute 89, aspartate 101 or leucine 137
RU2187118C2 (ru) * 2000-07-13 2002-08-10 Российский научно-исследовательский нейрохирургический институт им. проф. А.Л. Поленова Способ диагностики возможности рецидивов церебральных рацемозных артериовенозных мальформаций
IL141647A0 (en) 2001-02-26 2002-03-10 Yeda Res & Dev Synthetic human peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus
EP1583562B1 (en) 2003-01-06 2011-06-15 Angiochem Inc. Angiopep-1, related compounds, and uses thereof
AU2004206844A1 (en) 2003-01-14 2004-08-05 Teva Pharmaceutical Industries, Ltd. Parenteral formulations of a peptide for the treatment of systemic lupus erythematosus
ES2395087T3 (es) 2004-05-05 2013-02-08 Valorisation-Recherche, Société en Commandite Antagonistas del receptor de interleuquina-1, composiciones y métodos de tratamiento
US8618054B2 (en) 2004-05-05 2013-12-31 Valorisation-Rechereche Société en Commandite Interleukin-1 receptor antagonists, compositions, and methods of treatment
JP2008542685A (ja) 2005-05-05 2008-11-27 ヴァロリザーシヨン・アッシュエスジ，ソシエテ・アン・コマンディット サイトカイン受容体修飾因子及びその使用
US9365634B2 (en) 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
EP2789628A3 (en) 2007-05-29 2015-03-04 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
CN102026667B (zh) 2008-04-18 2014-06-25 安吉奥开米公司 紫杉醇、紫杉醇类似物或紫杉醇结合物的药物组合物及相关制备方法和用途
MX2011004017A (es) 2008-10-15 2011-06-24 Angiochem Inc Conjugados de agonistas glp-1 y usos de los mismos.
AU2009304505A1 (en) 2008-10-15 2010-04-22 Angiochem Inc. Etoposide and doxorubicin conjugates for drug delivery
AU2009322043A1 (en) 2008-12-05 2011-07-07 Angiochem Inc. Conjugates of neurotensin or neurotensin analogs and uses thereof
CN102300987A (zh) 2008-12-17 2011-12-28 安吉奥开米公司 膜型-1基质金属蛋白抑制剂及其用途
BRPI1015295A2 (pt) 2009-04-20 2016-05-31 Angiochem Inc traamento de câncer de ovário usando um agente anticâncer conjugado a um análogo angiopep-2.
CA2766537A1 (en) 2009-07-02 2011-01-06 Angiochem Inc. Multimeric peptide conjugates and uses thereof
MX2013000250A (es) 2010-07-02 2013-10-28 Angiochem Inc Polipeptidos cortos y que contienen d-aminoacido para conjugados terapeuticos y usos de los mismos.
MX2015015814A (es) * 2013-05-16 2016-06-02 Agency Science Tech & Res Sulfatos de heparán.
SG11201704086WA (en) 2014-11-19 2017-06-29 Agency Science Tech & Res Cosmetic use of heparan sulphate
WO2016080916A1 (en) 2014-11-19 2016-05-26 Agency For Science, Technology And Research Heparan sulphates for use in repair and/or regeneration of skin
WO2016205367A1 (en) 2015-06-15 2016-12-22 Angiochem Inc. Methods for the treatment of leptomeningeal carcinomatosis
CN105294851B (zh) * 2015-12-07 2019-02-12 中国科学院长春应用化学研究所 与几丁质特异结合的碱性成纤维细胞生长因子及其编码基因、制备方法与应用
CN114965839A (zh) * 2022-05-11 2022-08-30 朗肽生物制药股份有限公司 人碱性成纤维细胞生长因子的肽图分析方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4956455A (en) * 1984-03-05 1990-09-11 The Salk Institute For Biological Studies Bovine fibroblast growth factor
US4785079A (en) * 1984-11-09 1988-11-15 The Salk Institute For Biological Studies Isolation of fibroblast growth factor
US5026839A (en) * 1985-12-17 1991-06-25 Synergen, Inc DNA encoding a basic fibroblast growth factor
DE3811921A1 (de) * 1988-04-09 1989-10-19 Hoechst Ag Verfahren zur herstellung von proteinen, die n-terminal mit prolin beginnen
US5136025A (en) * 1990-04-04 1992-08-04 California Biotechnology Inc. Method to purify basic fibroblast growth factor

Also Published As

Publication number Publication date
CS236291A3 (en) 1992-02-19
CN1058597A (zh) 1992-02-12
DE69125810D1 (de) 1997-05-28
NO921236L (no) 1992-03-30
KR920702371A (ko) 1992-09-03
FI921428A0 (fi) 1992-04-01
FI921428A7 (fi) 1992-04-01
YU131991A (sh) 1994-05-10
KR100191697B1 (ko) 1999-06-15
NO301480B1 (no) 1997-11-03
PT98544B (pt) 1999-01-29
AU8304491A (en) 1992-03-02
IL98988A0 (en) 1992-07-15
CA2066174A1 (en) 1992-02-03
NO921236D0 (no) 1992-03-30
IE912729A1 (en) 1992-02-12
EP0495049B1 (en) 1997-04-23
ES2103822T3 (es) 1997-10-01
EP0495049A1 (en) 1992-07-22
GB9017008D0 (en) 1990-09-19
DK0495049T3 (da) 1997-08-25
RU2093519C1 (ru) 1997-10-20
US5348863A (en) 1994-09-20
MY107334A (en) 1995-11-30
GR3024111T3 (en) 1997-10-31
DE69125810T2 (de) 1997-08-07
AU643822B2 (en) 1993-11-25
CZ286237B6 (cs) 2000-02-16
PT98544A (pt) 1992-06-30
ATE152122T1 (de) 1997-05-15
FI921428L (fi) 1992-04-01
PH31240A (en) 1998-06-18
HU212671B (en) 1996-09-30
WO1992002539A1 (en) 1992-02-20
NZ239204A (en) 1993-11-25
CN1033810C (zh) 1997-01-15
HUT64564A (en) 1994-01-28
JPH05501655A (ja) 1993-04-02
ZA916026B (en) 1992-04-29
HU9201101D0 (en) 1992-08-28
YU48309B (sh) 1998-05-15

Similar Documents

Publication Publication Date Title
IL98988A0 (en) Enzymatic preparation of basic fibroblast growth factor
EP0528858A4 (en) Inhibitors of dipeptidyl-aminopeptidase type iv
EP1715057A3 (en) Methods of modifying carbohydrate moieties
DE69020794D1 (de) Enzymatische Entfernung einer aminoterminalen Proteinsequenz.
EP1277762A3 (en) Low allergenic protein variants
HU9401992D0 (en) A human kunitz-type protease inhibitor variant
EP0292220A3 (en) Condom
CA2232240A1 (en) Peptide for inhibiting growth of smooth muscle cells
WO1995015161A3 (de) Arzneimittel zur behandlung der herzinsuffizienz
CA2035917A1 (en) Stabilized sulfonate, sulfate, phosphonate and phosphate derivatives of hirudin
ES2147233T3 (es) Procedimiento de realizacion de motivos sobre objetos, especialmente articulos de ceramica.
EP0992513A3 (en) Isolated metallopeptide: compositions and synthetic methods
CA2114862A1 (en) Process for the synthesis of semi-synthetic glycosaminoglycans with heparin or heparan structure modified in position 2 of the .alpha.-l-iduronic-2-0-sulfate acid
FR2708603B1 (fr) Procédé de préparation d'hydroperoxyde de cumène.
SE9000793L (sv) Sdk-peptider,foerfarande foer framstaellning daerav och terapeutiska kompositioner innehaallande dem
CA2078000A1 (en) Neutrophil stimulating peptides
CA2234504A1 (en) Implantable tubular prosthesis
EP0414171A3 (en) Process for the enzymatic synthesis of components of galactosylated glycoproteins
DE59805677D1 (de) Froststabilisierung von wässrigen überzugsmitteln durch frostschutzproteine
Trickett BS 5750: Implications?
WO1995020602A3 (en) ANALOGS OF THYMOSIN α¿1?
HUT58832A (en) Galvanising bath for process for producing decorative chromine coating
IT1238692B (it) Composizioni farmaceutiche a base di calcitonina per la somministrazione sublinguale
IT8920399A0 (it) Procedimento perfezionato per la preparazione di superfici metalliche per l'applicazione di rivestimenti, particolarmente per la produzione di pentolame.

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
RH Patent void