IL98349A - ליפופפטיד דאצילאזה - Google Patents

ליפופפטיד דאצילאזה

Info

Publication number
IL98349A
IL98349A IL9834991A IL9834991A IL98349A IL 98349 A IL98349 A IL 98349A IL 9834991 A IL9834991 A IL 9834991A IL 9834991 A IL9834991 A IL 9834991A IL 98349 A IL98349 A IL 98349A
Authority
IL
Israel
Prior art keywords
deacylase
kcl
ala
activity
gly
Prior art date
Application number
IL9834991A
Other languages
English (en)
Other versions
IL98349A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL98349A0 publication Critical patent/IL98349A0/xx
Publication of IL98349A publication Critical patent/IL98349A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Prostheses (AREA)
  • External Artificial Organs (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Peptides Or Proteins (AREA)
IL9834991A 1990-06-07 1991-06-03 ליפופפטיד דאצילאזה IL98349A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53439490A 1990-06-07 1990-06-07

Publications (2)

Publication Number Publication Date
IL98349A0 IL98349A0 (en) 1992-07-15
IL98349A true IL98349A (he) 1995-05-26

Family

ID=24129856

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9834991A IL98349A (he) 1990-06-07 1991-06-03 ליפופפטיד דאצילאזה

Country Status (14)

Country Link
US (1) US5573936A (he)
EP (1) EP0460882B1 (he)
JP (1) JP2994486B2 (he)
KR (1) KR0169994B1 (he)
AT (1) ATE140728T1 (he)
CA (1) CA2043762C (he)
DE (1) DE69121018T2 (he)
DK (1) DK0460882T3 (he)
ES (1) ES2089133T3 (he)
GR (1) GR3021292T3 (he)
HU (1) HU215232B (he)
IE (1) IE75885B1 (he)
IL (1) IL98349A (he)
TW (1) TW197471B (he)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
KR100545506B1 (ko) * 1996-03-08 2006-10-04 아스테라스 세이야쿠 가부시키가이샤 환상 리포펩티드 물질의 탈아실화 방법
EP1666587A1 (en) * 1996-06-13 2006-06-07 Astellas Pharma Inc. Cyclic lipopeptide acylase
US6361988B1 (en) 1997-03-25 2002-03-26 California Institute Of Technology ECB deacylase mutants
US6153410A (en) * 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
US5936074A (en) * 1997-04-17 1999-08-10 Eli Lilly And Company Teicoplanin deacylation process and product
US6323176B1 (en) 1998-02-25 2001-11-27 Eli Lilly And Company Cyclic peptide antifungal agents
KR20010101151A (ko) 1998-12-09 2001-11-14 피터 지. 스트링거 에키노칸딘 시클로펩티드 화합물의 정제
JP2002538097A (ja) 1999-03-03 2002-11-12 イーライ リリー アンド カンパニー 薬学的経口ｅｃｂ処方物および組成物の作製方法
KR100613136B1 (ko) 1999-03-03 2006-08-17 일라이 릴리 앤드 캄파니 미셀-형성 계면활성제를 함유하는 에키노칸딘 제약학적조제물
ES2204548T3 (es) 1999-03-03 2004-05-01 Eli Lilly And Company Complejos de equinocandina/carbohidrato.
DE60030415T2 (de) 1999-03-03 2007-08-30 Eli Lilly And Co., Indianapolis Bildung und anionenaustausch von inneren kristallinen ammoniumsalzen des echinocandins b
EP1198471A1 (en) * 1999-07-15 2002-04-24 Eli Lilly And Company Process for deacylation of lipodepsipeptides
WO2001044272A2 (en) * 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Daptomycin analogs as antibacterial agents
BR0017028A (pt) * 1999-12-15 2003-01-07 Cubist Pharm Inc Lipopepìdeos como agentes antibacterianos
WO2001044274A1 (en) * 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
IL160171A0 (en) * 2001-08-06 2004-07-25 Cubist Pharm Inc Depsipeptide derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
DE102004060750A1 (de) * 2004-12-15 2006-07-13 Sanofi-Aventis Deutschland Gmbh Verfahren zur Deacylierung von Lipopeptiden
BRPI0923567A2 (pt) * 2008-12-22 2016-09-27 Cubist Pharm Inc agentes antibactericidas novos para o tratamento de infecções gram positivas
US9394340B2 (en) * 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
EP2897971B1 (en) 2012-09-24 2017-05-31 DSM Sinochem Pharmaceuticals Netherlands B.V. Method for producing a cyclic peptide
KR101425108B1 (ko) * 2012-09-25 2014-07-31 동국제약 주식회사 탈아실화된 환상 리포펩티드의 제조방법
CN108410929B (zh) * 2018-05-30 2024-01-26 博瑞生物医药（苏州）股份有限公司 阿尼芬净前体的制备方法
CN109593809A (zh) * 2018-12-07 2019-04-09 成都雅途生物技术有限公司 一种固定化微生物酶转化棘白菌素b的方法
CN113215185B (zh) * 2021-04-22 2022-04-29 浙江工业大学 一种用于重组表达棘白菌素b脱酰基酶的重组基因序列

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1159450A (en) * 1979-12-13 1983-12-27 Manuel Debono Process for the preparation of derivatives of cyclic peptide nuclei

Also Published As

Publication number Publication date
DE69121018D1 (de) 1996-08-29
IE911939A1 (en) 1991-12-18
IL98349A0 (en) 1992-07-15
IE75885B1 (en) 1997-09-24
HUT61587A (en) 1993-01-28
US5573936A (en) 1996-11-12
EP0460882A3 (en) 1992-04-22
EP0460882B1 (en) 1996-07-24
ATE140728T1 (de) 1996-08-15
TW197471B (he) 1993-01-01
EP0460882A2 (en) 1991-12-11
DE69121018T2 (de) 1996-12-19
HU911897D0 (en) 1991-12-30
CA2043762C (en) 2001-05-29
GR3021292T3 (en) 1997-01-31
CA2043762A1 (en) 1991-12-08
ES2089133T3 (es) 1996-10-01
JPH04228072A (ja) 1992-08-18
KR920000919A (ko) 1992-01-29
HU215232B (hu) 1998-11-30
DK0460882T3 (da) 1996-08-26
JP2994486B2 (ja) 1999-12-27
KR0169994B1 (ko) 1999-02-01

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