IL98070A0 - Muteins of the granulocyte colony stimulating factor(g-csf)and pharmaceutical compositions containing them - Google Patents

Muteins of the granulocyte colony stimulating factor(g-csf)and pharmaceutical compositions containing them

Info

Publication number
IL98070A0
IL98070A0 IL98070A IL9807091A IL98070A0 IL 98070 A0 IL98070 A0 IL 98070A0 IL 98070 A IL98070 A IL 98070A IL 9807091 A IL9807091 A IL 9807091A IL 98070 A0 IL98070 A0 IL 98070A0
Authority
IL
Israel
Prior art keywords
muteins
csf
pharmaceutical compositions
compositions containing
stimulating factor
Prior art date
Application number
IL98070A
Other languages
English (en)
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of IL98070A0 publication Critical patent/IL98070A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23K—SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
    • B23K26/00—Working by laser beam, e.g. welding, cutting or boring
    • B23K26/351—Working by laser beam, e.g. welding, cutting or boring for trimming or tuning of electrical components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Mechanical Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL98070A 1990-05-08 1991-05-06 Muteins of the granulocyte colony stimulating factor(g-csf)and pharmaceutical compositions containing them IL98070A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4014750A DE4014750A1 (de) 1990-05-08 1990-05-08 Muteine des granulozyten-stimulierenden faktors (g-csf)

Publications (1)

Publication Number Publication Date
IL98070A0 true IL98070A0 (en) 1992-06-21

Family

ID=6405959

Family Applications (1)

Application Number Title Priority Date Filing Date
IL98070A IL98070A0 (en) 1990-05-08 1991-05-06 Muteins of the granulocyte colony stimulating factor(g-csf)and pharmaceutical compositions containing them

Country Status (17)

Country Link
EP (1) EP0456200A1 (cs)
JP (1) JPH04225998A (cs)
KR (1) KR940000757B1 (cs)
CN (1) CN1057862A (cs)
AU (1) AU631312B2 (cs)
CA (1) CA2041439A1 (cs)
CS (1) CS133391A3 (cs)
DE (1) DE4014750A1 (cs)
FI (1) FI912203A7 (cs)
HU (1) HUT58801A (cs)
IE (1) IE911359A1 (cs)
IL (1) IL98070A0 (cs)
NO (1) NO911786L (cs)
NZ (1) NZ237975A (cs)
PL (1) PL290166A1 (cs)
PT (1) PT97611A (cs)
ZA (1) ZA913430B (cs)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5718893A (en) * 1984-04-15 1998-02-17 Foster; Preston F. Use of G-CSF to reduce acute rejection
GB9107846D0 (en) * 1990-04-30 1991-05-29 Ici Plc Polypeptides
US5581476A (en) * 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
US5536495A (en) * 1994-04-15 1996-07-16 Foster; Preston F. Use of G-CSF to reduce acute rejection
US20030053982A1 (en) 1994-09-26 2003-03-20 Kinstler Olaf B. N-terminally chemically modified protein compositions and methods
US5824784A (en) * 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
KR100440460B1 (ko) * 1998-07-08 2004-10-08 주식회사유한양행 인체 과립구 콜로니 자극인자의 유전자, 재조합 벡터 및 형질 전환체 및 그들을 이용한 인체 과립구 콜로니 자극인자의 제조방법
US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
DE19860801A1 (de) * 1998-12-30 2000-07-06 Rhein Biotech Proz & Prod Gmbh Rekombinanter Wachstumsfaktor mit der biologischen Aktivität eines G-CSF (Granulocyte Colony Stimulating Factor)
MXPA03002045A (es) 2000-09-08 2003-07-24 Amgen Inc Composiciones analogas de factor estimulador de colonias de granulocitos y metodos para su elaboracion.
WO2002069232A2 (en) 2001-02-19 2002-09-06 Merck Patent Gmbh Method for identification of t-cell epitopes and use for preparing molecules with reeduced immunogenicity
EP1425304B9 (en) 2001-07-11 2010-09-08 Maxygen, Inc. G-csf conjugates
US20040247562A1 (en) * 2001-09-28 2004-12-09 Sang Yup Lee Diagnostic method for cancer characterized in the detection of the deletion of g-csf exon 3
US7695723B2 (en) 2002-12-31 2010-04-13 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
US7785601B2 (en) 2002-12-31 2010-08-31 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
US7220407B2 (en) 2003-10-27 2007-05-22 Amgen Inc. G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
DE102004041639A1 (de) 2004-08-27 2006-03-02 Bioceuticals Arzneimittel Ag Verfahren zur Gewinnung von biologisch aktivem humanen G-CSF aus Inclusion Bodies
AU2005306894B2 (en) 2004-11-05 2011-11-24 Northwestern University Use of SCF and G-CSF in the treatment of cerebral ischemia and neurological disorders
KR20080027291A (ko) 2005-06-01 2008-03-26 맥시겐 홀딩스 엘티디 피이지화된 지-씨에스에프 폴리펩타이드 및 그 제조방법
DE102005033250A1 (de) 2005-07-15 2007-01-18 Bioceuticals Arzneimittel Ag Verfahren zur Reinigung von G-CSF
DE202006020194U1 (de) 2006-03-01 2007-12-06 Bioceuticals Arzneimittel Ag G-CSF-Flüssigformulierung
US20090324609A1 (en) 2007-08-09 2009-12-31 Genzyme Corporation Method of treating autoimmune disease with mesenchymal stem cells
DE102007040932A1 (de) 2007-08-27 2009-03-05 Biogenerix Ag Flüssigformulierung von G-CSF
MX2010002348A (es) 2007-08-27 2010-07-30 Biogenerix Ag Formulacion liquida de g-csf.
MX2010002448A (es) 2007-08-27 2010-10-04 Biogenerix Ag Formulacion liquida del g-csf conjugado.
WO2009046015A2 (en) 2007-09-30 2009-04-09 University Of Florida Research Foundation, Inc. Combination therapies for treating type 1 diabetes
EP2542574B1 (en) 2010-03-04 2017-08-09 Pfenex Inc. Method for producing soluble recombinant interferon protein without denaturing
AU2011235210B2 (en) 2010-04-01 2015-07-16 Pfenex Inc. Methods for G-CSF production in a Pseudomonas host cell
EP2399572A1 (en) 2010-06-22 2011-12-28 Sandoz AG Long-term storage of non-glycosylated recombinant human G-CSF

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06102021B2 (ja) * 1985-12-03 1994-12-14 中外製薬株式会社 新規なポリペプチド
JPS63500636A (ja) * 1985-08-23 1988-03-10 麒麟麦酒株式会社 多分化能性顆粒球コロニー刺激因子をコードするｄｎａ
AU7675487A (en) * 1986-08-11 1988-05-19 Cetus Corporation Expression of granulocyte colony-stimulating factor
WO1988003173A2 (en) * 1986-10-24 1988-05-05 Cetus Corporation New forms of colony stimulating factor-1
NO176799C (no) * 1986-12-23 1995-05-31 Kyowa Hakko Kogyo Kk DNA som koder for et polypeptid, rekombinant plasmid som koder for og kan uttrykke et polypeptid og fremgangsmåte for fremstilling av dette polypeptid

Also Published As

Publication number Publication date
CA2041439A1 (en) 1991-11-09
ZA913430B (en) 1992-02-26
PL290166A1 (en) 1992-01-13
FI912203L (fi) 1991-11-09
DE4014750A1 (de) 1991-11-14
KR910020033A (ko) 1991-12-19
IE911359A1 (en) 1991-11-20
HUT58801A (en) 1992-03-30
NO911786D0 (no) 1991-05-07
CS133391A3 (en) 1992-01-15
PT97611A (pt) 1992-03-31
AU7638091A (en) 1991-11-14
EP0456200A1 (de) 1991-11-13
CN1057862A (zh) 1992-01-15
FI912203A7 (fi) 1991-11-09
NZ237975A (en) 1992-09-25
HU911529D0 (en) 1991-11-28
NO911786L (no) 1991-11-11
FI912203A0 (fi) 1991-05-07
KR940000757B1 (ko) 1994-01-29
JPH04225998A (ja) 1992-08-14
AU631312B2 (en) 1992-11-19

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