AU631312B2 - Muteins of the granulocyte colony stimulating factor (g-csf) - Google Patents

Muteins of the granulocyte colony stimulating factor (g-csf)

Info

Publication number
AU631312B2
AU631312B2 AU76380/91A AU7638091A AU631312B2 AU 631312 B2 AU631312 B2 AU 631312B2 AU 76380/91 A AU76380/91 A AU 76380/91A AU 7638091 A AU7638091 A AU 7638091A AU 631312 B2 AU631312 B2 AU 631312B2
Authority
AU
Australia
Prior art keywords
muteins
csf
stimulating factor
colony stimulating
granulocyte colony
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU76380/91A
Other versions
AU7638091A (en
Inventor
Carola Dony
Gunther Schumacher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of AU7638091A publication Critical patent/AU7638091A/en
Application granted granted Critical
Publication of AU631312B2 publication Critical patent/AU631312B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23K—SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
    • B23K26/00—Working by laser beam, e.g. welding, cutting or boring
    • B23K26/351—Working by laser beam, e.g. welding, cutting or boring for trimming or tuning of electrical components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Plasma & Fusion (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU76380/91A 1990-05-08 1991-05-06 Muteins of the granulocyte colony stimulating factor (g-csf) Ceased AU631312B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4014750 1990-05-08
DE4014750A DE4014750A1 (en) 1990-05-08 1990-05-08 MUTEINE OF THE GRANULOCYTE-STIMULATING FACTOR (G-CSF)

Publications (2)

Publication Number Publication Date
AU7638091A AU7638091A (en) 1991-11-14
AU631312B2 true AU631312B2 (en) 1992-11-19

Family

ID=6405959

Family Applications (1)

Application Number Title Priority Date Filing Date
AU76380/91A Ceased AU631312B2 (en) 1990-05-08 1991-05-06 Muteins of the granulocyte colony stimulating factor (g-csf)

Country Status (17)

Country Link
EP (1) EP0456200A1 (en)
JP (1) JPH04225998A (en)
KR (1) KR940000757B1 (en)
CN (1) CN1057862A (en)
AU (1) AU631312B2 (en)
CA (1) CA2041439A1 (en)
CS (1) CS133391A3 (en)
DE (1) DE4014750A1 (en)
FI (1) FI912203A (en)
HU (1) HUT58801A (en)
IE (1) IE911359A1 (en)
IL (1) IL98070A0 (en)
NO (1) NO911786L (en)
NZ (1) NZ237975A (en)
PL (1) PL290166A1 (en)
PT (1) PT97611A (en)
ZA (1) ZA913430B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7381805B2 (en) 2005-06-01 2008-06-03 Maxygen Holdings, Ltd. Compositions comprising mixtures of positional PEG isomers of PEGylated G-CSF
US7550566B2 (en) 2000-01-10 2009-06-23 Maxygen Holdings Ltd. G-CSF conjugates

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5718893A (en) * 1984-04-15 1998-02-17 Foster; Preston F. Use of G-CSF to reduce acute rejection
GB9107846D0 (en) * 1990-04-30 1991-05-29 Ici Plc Polypeptides
US5581476A (en) 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
US5536495A (en) * 1994-04-15 1996-07-16 Foster; Preston F. Use of G-CSF to reduce acute rejection
US20030053982A1 (en) 1994-09-26 2003-03-20 Kinstler Olaf B. N-terminally chemically modified protein compositions and methods
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
KR100440460B1 (en) * 1998-07-08 2004-10-08 주식회사유한양행 Gene, recombinant vector and transformant of hG-CSF and method of producing hG-CSF using the same
US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
DE19860801A1 (en) * 1998-12-30 2000-07-06 Rhein Biotech Proz & Prod Gmbh Recombinant growth factor with the biological activity of a G-CSF (Granulocyte Colony Stimulating Factor)
AU9096001A (en) 2000-09-08 2002-03-22 Amgen Inc G-csf analog compositions and methods
HUP0303199A2 (en) 2001-02-19 2003-12-29 Merck Patent Gmbh Method for identification of t-cell epitopes and use for preparing molecules with reeduced immunogenicity
US7695723B2 (en) 2002-12-31 2010-04-13 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
US7785601B2 (en) 2002-12-31 2010-08-31 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
US7220407B2 (en) 2003-10-27 2007-05-22 Amgen Inc. G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
DE102004041639A1 (en) 2004-08-27 2006-03-02 Bioceuticals Arzneimittel Ag Method for obtaining biologically active human G-CSF from inclusion bodies
US20060153799A1 (en) 2004-11-05 2006-07-13 Northwestern University Use of SCF and G-CSF in the treatment of cerebral ischemia and neurological disorders
DE102005033250A1 (en) 2005-07-15 2007-01-18 Bioceuticals Arzneimittel Ag Process for purifying G-CSF
DE102006009437A1 (en) 2006-03-01 2007-09-13 Bioceuticals Arzneimittel Ag G-CSF liquid formulation
EP2581441A1 (en) 2007-08-09 2013-04-17 Genzyme Corporation Method of treating autoimmune disease with mesenchymal stem cells
EP2471510A1 (en) 2007-08-27 2012-07-04 BioGeneriX AG Liquid formulation of G-CSF
DE202007018629U1 (en) 2007-08-27 2008-12-24 Biogenerix Ag Liquid formulation of G-CSF
MX2010002448A (en) 2007-08-27 2010-10-04 Biogenerix Ag Liquid formulation of g-csf conjugate.
WO2009046015A2 (en) 2007-09-30 2009-04-09 University Of Florida Research Foundation, Inc. Combination therapies for treating type 1 diabetes
BR112012022292A2 (en) 2010-03-04 2017-01-10 Pfenex Inc method for producing recombinant soluble interferon protein without denaturation.
NZ603033A (en) 2010-04-01 2014-06-27 Pfenex Inc Methods for g-csf production in a pseudomonas host cell
EP2399572A1 (en) 2010-06-22 2011-12-28 Sandoz AG Long-term storage of non-glycosylated recombinant human G-CSF

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6298086A (en) * 1985-09-17 1987-03-19 Chugai Seiyaku Kabushiki Kaisha Human granulocyte colony stimulating factor
AU8007087A (en) * 1986-10-24 1988-04-28 Cetus Corporation New forms of colony stimulating factor-1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06102021B2 (en) * 1985-12-03 1994-12-14 中外製薬株式会社 Novel polypeptide
JPS63500636A (en) * 1985-08-23 1988-03-10 麒麟麦酒株式会社 DNA encoding multipotent granulocyte colony stimulating factor
EP0256843A1 (en) * 1986-08-11 1988-02-24 Cetus Corporation Expression of g-csf and muteins thereof and their use
DK174044B1 (en) * 1986-12-23 2002-05-06 Kyowa Hakko Kogyo Kk Polypeptide derived from human granulocyte colony stimulating factor, and method of preparation thereof, DNA encoding said polypeptide, recombinant plasmid containing said DNA, and microorganisms containing said recombinant plasmid .......

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6298086A (en) * 1985-09-17 1987-03-19 Chugai Seiyaku Kabushiki Kaisha Human granulocyte colony stimulating factor
AU8007087A (en) * 1986-10-24 1988-04-28 Cetus Corporation New forms of colony stimulating factor-1

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7550566B2 (en) 2000-01-10 2009-06-23 Maxygen Holdings Ltd. G-CSF conjugates
US7550565B2 (en) 2000-01-10 2009-06-23 Maxygen Holdings Ltd. G-CSF conjugates
US7696153B2 (en) 2000-01-10 2010-04-13 Maxygen, Inc. G-CSF conjugates
US7381805B2 (en) 2005-06-01 2008-06-03 Maxygen Holdings, Ltd. Compositions comprising mixtures of positional PEG isomers of PEGylated G-CSF
US7655766B2 (en) 2005-06-01 2010-02-02 Carsten Germansen Compositions comprising positional isomers of PEGylated G-CSF

Also Published As

Publication number Publication date
EP0456200A1 (en) 1991-11-13
PT97611A (en) 1992-03-31
CA2041439A1 (en) 1991-11-09
HUT58801A (en) 1992-03-30
IE911359A1 (en) 1991-11-20
CN1057862A (en) 1992-01-15
NO911786D0 (en) 1991-05-07
FI912203A (en) 1991-11-09
KR910020033A (en) 1991-12-19
AU7638091A (en) 1991-11-14
ZA913430B (en) 1992-02-26
KR940000757B1 (en) 1994-01-29
PL290166A1 (en) 1992-01-13
DE4014750A1 (en) 1991-11-14
NO911786L (en) 1991-11-11
CS133391A3 (en) 1992-01-15
JPH04225998A (en) 1992-08-14
HU911529D0 (en) 1991-11-28
NZ237975A (en) 1992-09-25
IL98070A0 (en) 1992-06-21
FI912203A0 (en) 1991-05-07

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