IL98070A0 - Muteins of the granulocyte colony stimulating factor(g-csf)and pharmaceutical compositions containing them - Google Patents

Muteins of the granulocyte colony stimulating factor(g-csf)and pharmaceutical compositions containing them

Info

Publication number
IL98070A0
IL98070A0 IL98070A IL9807091A IL98070A0 IL 98070 A0 IL98070 A0 IL 98070A0 IL 98070 A IL98070 A IL 98070A IL 9807091 A IL9807091 A IL 9807091A IL 98070 A0 IL98070 A0 IL 98070A0
Authority
IL
Israel
Prior art keywords
muteins
csf
pharmaceutical compositions
compositions containing
stimulating factor
Prior art date
Application number
IL98070A
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of IL98070A0 publication Critical patent/IL98070A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23K—SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
    • B23K26/00—Working by laser beam, e.g. welding, cutting or boring
    • B23K26/351—Working by laser beam, e.g. welding, cutting or boring for trimming or tuning of electrical components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plasma & Fusion (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL98070A 1990-05-08 1991-05-06 Muteins of the granulocyte colony stimulating factor(g-csf)and pharmaceutical compositions containing them IL98070A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4014750A DE4014750A1 (en) 1990-05-08 1990-05-08 MUTEINE OF THE GRANULOCYTE-STIMULATING FACTOR (G-CSF)

Publications (1)

Publication Number Publication Date
IL98070A0 true IL98070A0 (en) 1992-06-21

Family

ID=6405959

Family Applications (1)

Application Number Title Priority Date Filing Date
IL98070A IL98070A0 (en) 1990-05-08 1991-05-06 Muteins of the granulocyte colony stimulating factor(g-csf)and pharmaceutical compositions containing them

Country Status (17)

Country Link
EP (1) EP0456200A1 (en)
JP (1) JPH04225998A (en)
KR (1) KR940000757B1 (en)
CN (1) CN1057862A (en)
AU (1) AU631312B2 (en)
CA (1) CA2041439A1 (en)
CS (1) CS133391A3 (en)
DE (1) DE4014750A1 (en)
FI (1) FI912203A (en)
HU (1) HUT58801A (en)
IE (1) IE911359A1 (en)
IL (1) IL98070A0 (en)
NO (1) NO911786L (en)
NZ (1) NZ237975A (en)
PL (1) PL290166A1 (en)
PT (1) PT97611A (en)
ZA (1) ZA913430B (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5718893A (en) * 1984-04-15 1998-02-17 Foster; Preston F. Use of G-CSF to reduce acute rejection
GB9107846D0 (en) * 1990-04-30 1991-05-29 Ici Plc Polypeptides
US5581476A (en) * 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
US5536495A (en) * 1994-04-15 1996-07-16 Foster; Preston F. Use of G-CSF to reduce acute rejection
US20030053982A1 (en) 1994-09-26 2003-03-20 Kinstler Olaf B. N-terminally chemically modified protein compositions and methods
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
KR100440460B1 (en) * 1998-07-08 2004-10-08 주식회사유한양행 Gene, recombinant vector and transformant of hG-CSF and method of producing hG-CSF using the same
US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
DE19860801A1 (en) * 1998-12-30 2000-07-06 Rhein Biotech Proz & Prod Gmbh Recombinant growth factor with the biological activity of a G-CSF (Granulocyte Colony Stimulating Factor)
CA2421760A1 (en) 2000-09-08 2002-03-14 Massachusetts Institute Of Technology G-csf analog compositions and methods
WO2002069232A2 (en) 2001-02-19 2002-09-06 Merck Patent Gmbh Method for identification of t-cell epitopes and use for preparing molecules with reeduced immunogenicity
JP4444652B2 (en) 2001-07-11 2010-03-31 マキシゲン・ホールディングズ・リミテッド G-CSF conjugate
US7695723B2 (en) 2002-12-31 2010-04-13 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
US7785601B2 (en) 2002-12-31 2010-08-31 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
US7220407B2 (en) 2003-10-27 2007-05-22 Amgen Inc. G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
DE102004041639A1 (en) 2004-08-27 2006-03-02 Bioceuticals Arzneimittel Ag Method for obtaining biologically active human G-CSF from inclusion bodies
EP1817047B1 (en) 2004-11-05 2012-02-08 Northwestern University Use of scf and g-csf in the treatment of cerebral ischemia and neurological disorders
CN101193658B (en) 2005-06-01 2011-08-31 马克西根控股公司 Pegylated G-CSF polypeptides and methods of producing same
DE102005033250A1 (en) 2005-07-15 2007-01-18 Bioceuticals Arzneimittel Ag Process for purifying G-CSF
DE202006020194U1 (en) 2006-03-01 2007-12-06 Bioceuticals Arzneimittel Ag G-CSF liquid formulation
EP2185689A2 (en) 2007-08-09 2010-05-19 Genzyme Corporation Method of treating autoimmune disease with mesenchymal stem cells
DE202007018629U1 (en) 2007-08-27 2008-12-24 Biogenerix Ag Liquid formulation of G-CSF
BRPI0815280A2 (en) 2007-08-27 2018-11-27 Biogenerix Ag medicament comprising an aqueous liquid formulation of g-csf, receptacle for the administration of liquid medicaments, syringe or ampoule, kit for parenteral administration of g-csf
RS53404B (en) 2007-08-27 2014-10-31 Ratiopharm Gmbh Liquid formulation of g-csf conjugate
WO2009046015A2 (en) 2007-09-30 2009-04-09 University Of Florida Research Foundation, Inc. Combination therapies for treating type 1 diabetes
ES2639398T3 (en) 2010-03-04 2017-10-26 Pfenex Inc. Method for producing soluble recombinant interferon protein without denaturation
US8455218B2 (en) 2010-04-01 2013-06-04 Pfenex, Inc. Methods for G-CSF production in a Pseudomonas host cell
EP2399572A1 (en) 2010-06-22 2011-12-28 Sandoz AG Long-term storage of non-glycosylated recombinant human G-CSF

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06102021B2 (en) * 1985-12-03 1994-12-14 中外製薬株式会社 Novel polypeptide
JPS63500636A (en) * 1985-08-23 1988-03-10 麒麟麦酒株式会社 DNA encoding multipotent granulocyte colony stimulating factor
JPH01500483A (en) * 1986-08-11 1989-02-23 シタス　コーポレイション Expression of G-CSF and its muteins
HU215241B (en) * 1986-10-24 1998-11-30 Cetus Corp. Process for producing new forms of colony stimulating factor-1 and expression cassette, vector and recombinant host cells used in the process
DK174044B1 (en) * 1986-12-23 2002-05-06 Kyowa Hakko Kogyo Kk Polypeptide derived from human granulocyte colony stimulating factor, and method of preparation thereof, DNA encoding said polypeptide, recombinant plasmid containing said DNA, and microorganisms containing said recombinant plasmid .......

Also Published As

Publication number Publication date
PT97611A (en) 1992-03-31
NO911786L (en) 1991-11-11
DE4014750A1 (en) 1991-11-14
NZ237975A (en) 1992-09-25
JPH04225998A (en) 1992-08-14
FI912203A (en) 1991-11-09
CA2041439A1 (en) 1991-11-09
FI912203A0 (en) 1991-05-07
CN1057862A (en) 1992-01-15
AU631312B2 (en) 1992-11-19
CS133391A3 (en) 1992-01-15
HUT58801A (en) 1992-03-30
NO911786D0 (en) 1991-05-07
AU7638091A (en) 1991-11-14
HU911529D0 (en) 1991-11-28
EP0456200A1 (en) 1991-11-13
PL290166A1 (en) 1992-01-13
KR910020033A (en) 1991-12-19
ZA913430B (en) 1992-02-26
KR940000757B1 (en) 1994-01-29
IE911359A1 (en) 1991-11-20

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