IL96655A - נוגדנים מונוקלונלים המגיבים עם אנטיגן הקשור לאתרומה של אדם - Google Patents
נוגדנים מונוקלונלים המגיבים עם אנטיגן הקשור לאתרומה של אדםInfo
- Publication number
- IL96655A IL96655A IL9665590A IL9665590A IL96655A IL 96655 A IL96655 A IL 96655A IL 9665590 A IL9665590 A IL 9665590A IL 9665590 A IL9665590 A IL 9665590A IL 96655 A IL96655 A IL 96655A
- Authority
- IL
- Israel
- Prior art keywords
- antibody
- antigen
- hybridoma cell
- cell line
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45139989A | 1989-12-15 | 1989-12-15 | |
US07/599,549 US5196324A (en) | 1989-12-15 | 1990-10-17 | Monoclonal antibodies reactive with a human atheroma associated antigen |
Publications (2)
Publication Number | Publication Date |
---|---|
IL96655A0 IL96655A0 (en) | 1991-09-16 |
IL96655A true IL96655A (he) | 1995-12-31 |
Family
ID=27036357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9665590A IL96655A (he) | 1989-12-15 | 1990-12-13 | נוגדנים מונוקלונלים המגיבים עם אנטיגן הקשור לאתרומה של אדם |
Country Status (9)
Country | Link |
---|---|
US (2) | US5196324A (he) |
EP (1) | EP0433088B1 (he) |
JP (1) | JPH04159300A (he) |
AT (1) | ATE154613T1 (he) |
AU (1) | AU639282B2 (he) |
CA (1) | CA2032359A1 (he) |
DE (1) | DE69030947D1 (he) |
DK (1) | DK0433088T3 (he) |
IL (1) | IL96655A (he) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5955584A (en) * | 1986-03-31 | 1999-09-21 | Charter Ventures | Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof |
US5811248A (en) * | 1986-03-31 | 1998-09-22 | Charter Ventures | Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof |
US6025477A (en) * | 1986-03-31 | 2000-02-15 | Calenoff; Emanuel | Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof |
JP3115587B2 (ja) * | 1990-11-07 | 2000-12-11 | 第一化学薬品株式会社 | モノクローナル抗体及びマロンジアルデヒド化低比重リポタンパクの測定法 |
WO1994008038A1 (en) * | 1992-10-02 | 1994-04-14 | Trustees Of Dartmouth College | Bispecific reagents for redirected targeting of low density lipoprotein |
US5753227A (en) | 1993-07-23 | 1998-05-19 | Strahilevitz; Meir | Extracorporeal affinity adsorption methods for the treatment of atherosclerosis, cancer, degenerative and autoimmune diseases |
JP4044972B2 (ja) * | 1994-02-24 | 2008-02-06 | 協和メデックス株式会社 | ヒト粥状硬化病巣関連抗原を認識するモノクローナル抗体 |
US5449679A (en) * | 1994-07-29 | 1995-09-12 | Leonard; Robert J. | Process and products for reducing biological fluid levels of a lipid soluble waste |
US6605588B1 (en) | 1996-11-27 | 2003-08-12 | Boston Heart Foundation, Inc. | Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis |
US6355451B1 (en) | 1996-11-27 | 2002-03-12 | Boston Heart Foundation, Inc. | Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis |
US6632923B1 (en) * | 1996-11-27 | 2003-10-14 | Boston Heart Foundation, Inc. | Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis |
US6727102B1 (en) | 1997-06-20 | 2004-04-27 | Leuven Research & Development Vzw | Assays, antibodies, and standards for detection of oxidized and MDA-modified low density lipoproteins |
US6225070B1 (en) * | 1997-08-07 | 2001-05-01 | The Regents Of The University Of California | Antibodies to oxidation-specific epitopes on lipoprotein and methods for their use in detecting, monitoring and inhibiting the growth of atheroma |
US6309888B1 (en) * | 1998-09-04 | 2001-10-30 | Leuven Research & Development Vzw | Detection and determination of the stages of coronary artery disease |
US20050197283A1 (en) * | 1998-10-04 | 2005-09-08 | Vascular Biogenics Ltd. | Compositions containing beta 2-glycoprotein I for the prevention and/or treatment of vascular disease |
IL126447A (he) * | 1998-10-04 | 2004-09-27 | Vascular Biogenics Ltd | תכשיר חיסוני המקנה סבילות במתן פומי ושימושו במניעה ו/או טיפול בטרשת עורקים |
WO2004030607A2 (en) * | 2002-10-04 | 2004-04-15 | Forskarpatent I Syd Ab | Peptide-based passive immunization therapy for treatment of atherosclerosis |
SE0302312D0 (sv) * | 2002-10-04 | 2003-08-27 | Forskarpatent I Syd Ab | Peptide-based passive immunization therapy for treatment of atherosclerosis |
US20050181451A1 (en) * | 2004-02-12 | 2005-08-18 | Bates Harold M. | Detection of asymptomatic coronary artery disease using atherogenic proteins and acute phase reactants |
US8129123B2 (en) | 2004-10-05 | 2012-03-06 | The Regents Of The University Of California | Methods for assessing atherogenesis by determining oxidized phospholipid to apolipoprotein B ratios |
WO2006109312A2 (en) * | 2005-04-15 | 2006-10-19 | Vascular Biogenics Ltd. | Compositions containing beta 2-glycoprotein i-derived peptides for the prevention and/or treatment of vascular disease |
US20090163698A1 (en) * | 2007-05-11 | 2009-06-25 | John Joseph Grigsby | Method for Preparing Antibody Conjugates |
CU23736A1 (es) | 2009-05-04 | 2011-11-15 | Centro Inmunologia Molecular | Anticuerpos que reconocen sulfatidos y proteoglicanos sulfatados y su uso |
JP5854474B2 (ja) * | 2010-04-28 | 2016-02-09 | 国立大学法人北海道大学 | 軽度に酸化された酸化低密度リポタンパク質に対するモノクローナル抗体およびこれを産生するハイブリドーマ |
AU2016233398A1 (en) * | 2015-03-16 | 2017-09-07 | F. Hoffmann-La Roche Ag | Methods of detecting and quantifying IL-13 and uses in diagnosing and treating Th2-associated diseases |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4376110A (en) * | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
US4632901A (en) * | 1984-05-11 | 1986-12-30 | Hybritech Incorporated | Method and apparatus for immunoassays |
JPS61130238A (ja) * | 1984-11-30 | 1986-06-18 | Res Dev Corp Of Japan | 動脈硬化巣認識モノクロナル抗体および反応試薬 |
US4885256A (en) * | 1986-06-17 | 1989-12-05 | The United States Of America As Represented By The United States Army | Monoclonal antibodies to cholesterol and methods |
EP0250119A3 (en) * | 1986-06-20 | 1990-04-18 | Vasocor | Atherosclerotic anti-idiotype antibody immunoassay and reagents |
IL84160A0 (en) * | 1986-10-16 | 1988-03-31 | Vasocor | Method and kit for immune complex assay |
EP0293524A1 (en) * | 1987-06-02 | 1988-12-07 | Vasocor | Atherosclerotic plaque immunoassay |
EP0327418B1 (fr) * | 1988-01-19 | 1995-04-12 | Institut Pasteur | Procédé immunométrique pour le dosage de particules de lipoprotéine, anticorps monoclonaux anti-Lp(a) et application au diagnostic de l'athérosclérose |
CA1320461C (en) * | 1988-02-04 | 1993-07-20 | Tatsuya Takano | Monoclonal antibody capable of recognizing human arteriosclerosis and process for preparing same |
US4945040A (en) * | 1988-02-29 | 1990-07-31 | Arch Development Corporation | Immunoassay for lipoprotein(a) |
CA2060663A1 (en) * | 1989-07-31 | 1991-02-01 | Emanuel Calenoff | Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof |
-
1990
- 1990-10-17 US US07/599,549 patent/US5196324A/en not_active Expired - Lifetime
- 1990-12-13 IL IL9665590A patent/IL96655A/he not_active IP Right Cessation
- 1990-12-14 AT AT90313688T patent/ATE154613T1/de not_active IP Right Cessation
- 1990-12-14 EP EP90313688A patent/EP0433088B1/en not_active Revoked
- 1990-12-14 DE DE69030947T patent/DE69030947D1/de not_active Expired - Lifetime
- 1990-12-14 JP JP2410826A patent/JPH04159300A/ja not_active Withdrawn
- 1990-12-14 DK DK90313688.5T patent/DK0433088T3/da active
- 1990-12-14 CA CA002032359A patent/CA2032359A1/en not_active Abandoned
- 1990-12-14 AU AU68135/90A patent/AU639282B2/en not_active Ceased
-
1995
- 1995-03-30 US US08/413,738 patent/US5597726A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU639282B2 (en) | 1993-07-22 |
US5597726A (en) | 1997-01-28 |
IL96655A0 (en) | 1991-09-16 |
DK0433088T3 (da) | 1997-07-07 |
CA2032359A1 (en) | 1991-06-16 |
ATE154613T1 (de) | 1997-07-15 |
EP0433088A1 (en) | 1991-06-19 |
AU6813590A (en) | 1991-06-20 |
JPH04159300A (ja) | 1992-06-02 |
DE69030947D1 (de) | 1997-07-24 |
US5196324A (en) | 1993-03-23 |
EP0433088B1 (en) | 1997-06-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |