IL96397A - 5-fluoro and 6-fluoro-2-[(4-cyclopropyl-methoxy-2-pyridinyl) methyl] sulfinyl-1h-benzimidazole-1- yl-methyl ethyl carbonates their preparation and compositions for use in inhibiting gastric acid secretionin mammals - Google Patents

5-fluoro and 6-fluoro-2-[(4-cyclopropyl-methoxy-2-pyridinyl) methyl] sulfinyl-1h-benzimidazole-1- yl-methyl ethyl carbonates their preparation and compositions for use in inhibiting gastric acid secretionin mammals

Info

Publication number
IL96397A
IL96397A IL9639790A IL9639790A IL96397A IL 96397 A IL96397 A IL 96397A IL 9639790 A IL9639790 A IL 9639790A IL 9639790 A IL9639790 A IL 9639790A IL 96397 A IL96397 A IL 96397A
Authority
IL
Israel
Prior art keywords
compound
fluoro
formula
methyl
compounds
Prior art date
Application number
IL9639790A
Other languages
English (en)
Other versions
IL96397A0 (en
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of IL96397A0 publication Critical patent/IL96397A0/xx
Publication of IL96397A publication Critical patent/IL96397A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fertilizers (AREA)
IL9639790A 1989-12-20 1990-11-19 5-fluoro and 6-fluoro-2-[(4-cyclopropyl-methoxy-2-pyridinyl) methyl] sulfinyl-1h-benzimidazole-1- yl-methyl ethyl carbonates their preparation and compositions for use in inhibiting gastric acid secretionin mammals IL96397A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/454,048 US5049674A (en) 1989-12-20 1989-12-20 Therapeutically active fluoro substituted benzimidazoles

Publications (2)

Publication Number Publication Date
IL96397A0 IL96397A0 (en) 1991-08-16
IL96397A true IL96397A (en) 1995-10-31

Family

ID=23803077

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9639790A IL96397A (en) 1989-12-20 1990-11-19 5-fluoro and 6-fluoro-2-[(4-cyclopropyl-methoxy-2-pyridinyl) methyl] sulfinyl-1h-benzimidazole-1- yl-methyl ethyl carbonates their preparation and compositions for use in inhibiting gastric acid secretionin mammals

Country Status (22)

Country Link
US (1) US5049674A (lt)
EP (1) EP0506759A1 (lt)
JP (1) JPH05502448A (lt)
KR (1) KR927003573A (lt)
CN (1) CN1052670A (lt)
AU (1) AU641465B2 (lt)
CA (1) CA2070651A1 (lt)
EG (1) EG19360A (lt)
FI (1) FI922864A0 (lt)
HU (1) HUT61995A (lt)
IE (1) IE904248A1 (lt)
IL (1) IL96397A (lt)
IS (1) IS3658A7 (lt)
LT (1) LT3809B (lt)
LV (1) LV10952A (lt)
NO (1) NO922437L (lt)
NZ (1) NZ236102A (lt)
PL (1) PL167703B1 (lt)
PT (1) PT96256A (lt)
WO (1) WO1991009028A1 (lt)
YU (1) YU47750B (lt)
ZA (1) ZA909142B (lt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2093445T3 (es) * 1992-07-28 1996-12-16 Astra Ab Inyeccion y estuche de inyeccion que contiene omeprazol y sus analogos.
GB9423970D0 (en) * 1994-11-28 1995-01-11 Astra Ab Oxidation
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US176308A (en) 1876-04-18 Improvement in buttons
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (lt) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
HU195220B (en) * 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
NZ234564A (en) * 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
FI96860C (fi) * 1987-06-17 1996-09-10 Eisai Co Ltd Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
ZA889194B (en) * 1987-12-11 1989-08-30 Byk Gulden Lomberg Chemisch Fa Novel benzimidazole derivatives

Also Published As

Publication number Publication date
AU641465B2 (en) 1993-09-23
PT96256A (pt) 1991-09-30
YU237190A (sh) 1994-11-15
CA2070651A1 (en) 1991-06-21
IL96397A0 (en) 1991-08-16
FI922864A (fi) 1992-06-18
HUT61995A (en) 1993-03-29
HU9202071D0 (en) 1992-09-28
WO1991009028A1 (en) 1991-06-27
LTIP1732A (en) 1995-08-25
FI922864A0 (fi) 1992-06-18
KR927003573A (ko) 1992-12-18
NO922437L (no) 1992-08-13
LV10952A (lv) 1995-12-20
AU7038091A (en) 1991-07-18
EP0506759A1 (en) 1992-10-07
CN1052670A (zh) 1991-07-03
NO922437D0 (no) 1992-06-19
YU47750B (sh) 1996-01-08
IS3658A7 (is) 1991-06-21
PL288337A1 (en) 1991-12-02
NZ236102A (en) 1992-12-23
ZA909142B (en) 1991-08-28
IE904248A1 (en) 1991-07-03
EG19360A (en) 1994-12-30
US5049674A (en) 1991-09-17
LT3809B (en) 1996-03-25
JPH05502448A (ja) 1993-04-28
PL167703B1 (en) 1995-10-31

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Legal Events

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RH Patent void