IL96064A - History of 2-] 1-Paneoxy-2-phenylalkyl [imidazoline and 2, 2, 3, 4-tetrahydro-pyrimidine and medicinal preparations containing them - Google Patents

History of 2-] 1-Paneoxy-2-phenylalkyl [imidazoline and 2, 2, 3, 4-tetrahydro-pyrimidine and medicinal preparations containing them

Info

Publication number
IL96064A
IL96064A IL9606490A IL9606490A IL96064A IL 96064 A IL96064 A IL 96064A IL 9606490 A IL9606490 A IL 9606490A IL 9606490 A IL9606490 A IL 9606490A IL 96064 A IL96064 A IL 96064A
Authority
IL
Israel
Prior art keywords
represented
benzo
compound according
compounds
integer
Prior art date
Application number
IL9606490A
Other languages
English (en)
Hebrew (he)
Other versions
IL96064A0 (en
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of IL96064A0 publication Critical patent/IL96064A0/xx
Publication of IL96064A publication Critical patent/IL96064A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL9606490A 1989-10-20 1990-10-19 History of 2-] 1-Paneoxy-2-phenylalkyl [imidazoline and 2, 2, 3, 4-tetrahydro-pyrimidine and medicinal preparations containing them IL96064A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42442989A 1989-10-20 1989-10-20

Publications (2)

Publication Number Publication Date
IL96064A0 IL96064A0 (en) 1991-07-18
IL96064A true IL96064A (en) 1994-11-28

Family

ID=23682608

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9606490A IL96064A (en) 1989-10-20 1990-10-19 History of 2-] 1-Paneoxy-2-phenylalkyl [imidazoline and 2, 2, 3, 4-tetrahydro-pyrimidine and medicinal preparations containing them

Country Status (21)

Country Link
EP (1) EP0423802B1 (da)
JP (1) JP3097696B2 (da)
KR (1) KR0182808B1 (da)
CN (1) CN1028099C (da)
AR (1) AR248400A1 (da)
AT (1) ATE126217T1 (da)
AU (1) AU627627B2 (da)
CA (1) CA2027530C (da)
DE (1) DE69021490T2 (da)
DK (1) DK0423802T3 (da)
ES (1) ES2088936T3 (da)
FI (1) FI104717B (da)
GR (1) GR3017775T3 (da)
HU (1) HU207300B (da)
IE (1) IE67049B1 (da)
IL (1) IL96064A (da)
NO (1) NO179367C (da)
NZ (1) NZ235688A (da)
PH (1) PH27290A (da)
PT (1) PT95637B (da)
ZA (1) ZA908234B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2156868T3 (es) * 1992-02-06 2001-08-01 Merrell Pharma Inc Compuestos de arilalcoxifenoxi-imidazolina.
KR100693139B1 (ko) * 2001-04-19 2007-03-13 엘지전자 주식회사 디스크 드라이브의 트레이 진동방지구조
KR100482010B1 (ko) 2002-11-05 2005-04-14 삼성전자주식회사 모니터장치
EP1958507A1 (en) 2007-02-15 2008-08-20 Syngeta Participations AG Chemical compounds
WO2009003868A2 (en) * 2007-07-02 2009-01-08 F. Hoffmann-La Roche Ag 2 -imidazolines having a good affinity to the trace amine associated receptors (taars)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE614596C (de) * 1931-07-10 1935-06-13 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von ?-Glyoxalidinarylmethylolen
US2893993A (en) * 1958-06-17 1959-07-07 Searle & Co 2-aryloxyaralkyl-1, 4, 5, 6-tetrahydropyrimidines
US3897431A (en) * 1969-04-24 1975-07-29 Sterling Drug Inc 2-{8 {60 -Alkoxy-arylmethyl{9 -2-imidazolines and -1,4,5,6-tetrahydropyrimidines
NL7804482A (nl) * 1977-04-29 1978-10-31 Ciba Geigy Preparaten ter bestrijding van ectoparasieten.
DE2961710D1 (en) * 1978-10-09 1982-02-18 Ciba Geigy Ag 2-(alpha-phenoxy-alkyl)-imidazolines and their salts, their preparation and use, and agents against phytoparasitic and zooparasitic mites containing them
US4260626A (en) * 1979-03-26 1981-04-07 Richardson-Merrell Inc. Tetrahydro and imidazoline antisecretory compounds
IT1231237B (it) * 1987-09-21 1991-11-26 Angeli Inst Spa Derivati eterociclici

Also Published As

Publication number Publication date
NZ235688A (en) 1992-02-25
PT95637A (pt) 1991-09-13
CN1051039A (zh) 1991-05-01
DK0423802T3 (da) 1995-09-18
HU906514D0 (en) 1991-04-29
ES2088936T3 (es) 1996-10-01
JPH03135960A (ja) 1991-06-10
PT95637B (pt) 1998-04-30
DE69021490T2 (de) 1996-02-01
GR3017775T3 (en) 1996-01-31
NO904535L (no) 1991-04-22
ATE126217T1 (de) 1995-08-15
HUT55366A (en) 1991-05-28
AU6456590A (en) 1991-04-26
HU207300B (en) 1993-03-29
ZA908234B (en) 1991-08-28
JP3097696B2 (ja) 2000-10-10
PH27290A (en) 1993-05-04
AR248400A1 (es) 1995-08-18
IE67049B1 (en) 1996-02-21
IE903765A1 (en) 1991-04-24
EP0423802B1 (en) 1995-08-09
NO904535D0 (no) 1990-10-19
FI905168A0 (fi) 1990-10-19
CN1028099C (zh) 1995-04-05
DE69021490D1 (de) 1995-09-14
IL96064A0 (en) 1991-07-18
AU627627B2 (en) 1992-08-27
KR0182808B1 (ko) 1999-05-01
CA2027530A1 (en) 1991-04-21
EP0423802A1 (en) 1991-04-24
NO179367C (no) 1996-09-25
CA2027530C (en) 2001-05-08
KR910007887A (ko) 1991-05-30
NO179367B (no) 1996-06-17
FI104717B (fi) 2000-03-31

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Legal Events

Date Code Title Description
KB Patent renewed
HC Change of name of proprietor(s)
HP Change in proprietorship
RH Patent void
MM9K Patent not in force due to non-payment of renewal fees
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INCORPORATED